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INDONESIA
JURNAL KESEHATAN YAMASI MAKASSAR
Published by Akademi Farmasi Yamasi Makassar
ISSN : 25488279     EISSN : 28091876     DOI : https://doi.org/10.59060/jurkes.v7i1.250
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Jurnal ini memuat naskah hasil penelitian dengan kajian ilmiah yang berkaitan dengan bidang kesehatan secara umum dan bidang farmasi khususnya. Sebuah jurnal yang didedikasikan untuk publikasi hasil penelitian seluruh aspek ilmu farmasi sebagai berikut : farmasetika, kimia farmasi, biologi farmasi, bioteknologi farmasi, serta farmakologi dan farmasi klinik, namun tak terbatas secara implisit. Jurnal ini terbit dua kali dalam setahun yaitu setiap bulan Januari dan Juli.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 257 Documents
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FORMULASI DAN UJI AKTIVITAS ANTI JAMUR OBAT KUMUR EKSTRAK SARANG SEMUT (Myrmecodia platyrae) TERHADAP JAMUR Candida Albicans Rusmin, Rusmin
Jurnal Kesehatan Yamasi Makassar Vol. 7 No. 2 (2023): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v7i2.295

Abstract

Abstract. This study aims to make a mouthwash formula from ant nest extract (Myrmecodia platyrae) using various extract concentrations of 5%w/v, 10% w/v and 15% w/v. The research design used was laboratory experimental. In this study, ant nest extract was formulated into a mouthwash with a concentration of F1 5% w/v, F2 10% w/v and F3 15% w/v and then activity was tested against Candida albicans using the paper disk method. Physical stability tests for mouthwash preparations using ant nest extract included organoleptic tests, pH tests, homogeneity tests, and stability tests as well as phytochemical screening tests. Based on the results of the study obtained from ant nest extract mouthwash inhibition zone which was produced during the incubation period of 1 x 24 hours F1 10.40 mm, F2 11.32 mm, F3 11.88 mm, positive control 14.67 and during the incubation period 2 x 24 hours obtained F1 11.34 mm, F2 12.02 mm, F3 12.91, positive control 26.44 indicating an inhibitory effect on the growth of Candida albicans
PEMBUATAN DAN UJI MUTU FISIK KRIM EKSTRAK HERBA PEGAGAN (Centella asiatica) (L.) dzulasfi; Suhartini; Agha Izha Fahiza
Jurnal Kesehatan Yamasi Makassar Vol. 7 No. 2 (2023): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v7i2.304

Abstract

This study aims to make and test the Physical Quality Test of Centtella asiatica (L) extract of Centtella asiatica (L) in cream dosage forms with 0.5% and 1% extract concentrations. The type of research carried out is a laboratory experimental research by making Centella asiatica (L) herbal cream and testing the physical quality of the cream by conducting organoleptic, homogeneity, pH and dispersibility tests. The results of the observation of the pH test at a concentration of 0.5% is 6.13, a concentration of 1% is 6.47 while the dispersion test at a concentration of 0.5% is 5.1 cm, and a concentration of 1% is 5.2 cm. The results of the research on making and testing the physical quality of the cream of gotu kola herb extract 0.5% and 1% met the requirements for the physical quality test of cream preparations.
PENENTUAN NILAI SUN PROTECTION FACTOR (SPF) EKSTRAK ETANOL RIMPANG BANGLE (Zingiber purpureum Rovb.) SECARA SPEKTROFOTOMETRI UV-Vis sukirawati, sukirawati; Yusriyani
Jurnal Kesehatan Yamasi Makassar Vol. 7 No. 2 (2023): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v7i2.305

Abstract

Research has been conducted on the determination of the value of Sun Protection Factor (SPF) extract of rhizome bangle (Zingiber purpureum Roxb.) in spectrophotometer UV-Vis As an active ingredient of sunscreen. This study aims to determine the SPF value using the UV-Vis spectrophotometry method. Rhizome bangle extracted by maceration method using 96% ethanol solvent, then made in a concentration of sample solution 10 ppm, 20 ppm, 30 ppm 40 ppm and 50 ppm. The solution was then measured for absorbance in a UV-Vis spectrophotometer with a wavelength of 290-320 and an interval of 5 nm. Calculation of SPF values using the Petro method, and the results of the study showed that rhizome bangle extract had activity as a dark veil with a minimum level of protection sun protection at a concentration of 20 ppm with a value of SPF 3,60003. A concentration of 30 ppm shows extra protection with an SPF value of 6.30566. The concentration of 40 ppm showed maximum protection with a value of SPF 9,38396 and a concentration of 50 ppm indicating ultra-protil with a value of SPF 28,10936. Based on the results of these tests also obtained a linear relationship between concentration and SPF value.
FORMULASI DAN UJI STABILITAS FISIK FACIAL WASH EKSTRAK ETANOL DAUN KITOLOD (Isotoma longiflora L.) SERTA AKTIVITASNYA TERHADAP Staphylococcus epidermidis Basir, Hernawati; Istianah Purnamasari; Thalib, Muthmainna; A. Tenriugi Daeng Pine; Saldi; Nadia Pratama Nurka Sari
Jurnal Kesehatan Yamasi Makassar Vol. 8 No. 2 (2024): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v8i2.190

Abstract

Daun kitolod merupakan tumbuhan yang jarang dilirik oleh masyarakat secara umum, tumbuhan ini tumbuh liar dan mudah ditemukan. Daun kitolod (Isotoma longiflora L.) mengandung senyawa seperti flavonoid, alkaloid, saponin, dan politerol. Penelitian ini bertujuan untuk memformulasi sediaan facial wash ekstrak etanol daun kitolod dan uji stabilitas fisik serta menguji aktivitasnya terhadap Staphylococcus epidermidis. Metode yang digunakan pada penelitian ini adalah eksperimental laboratorium dimana dilakukan uji stabilitas fisik sediaan facial wash ekstrak etanol daun kitolod (Isotoma longiflora L.) berupa uji organoleptik, pH, homogenitas, daya sebar, daya busa, viskositas, iritasi terhadap kulit, stabilitas penyimpanan, dan aktivitasnya terhadap Staphylococcus epidermidis. Ekstrak etanol daun kitolod (Isotoma longiflora L.) kemudian diformulasikan menjadi sediaan facial wash yang dibuat dalam 3 formulasi yaitu F0:0%, F1:15%, F2:20%. Berdasarkan hasil uji stabilitas fisik Hasil evaluasi uji pH F0, F1, dan F2 berurut adalah 5,3; 5,1 dan 5,1. Hasil uji homogenitas semua formulasi menunjukkan bahwa sediaan homogen. Hasil viskositas F0, F1, dan F2 berurut yaitu 1100 cPs; 553,3 cPs dan 600 Cps. Hasil uji iritasi pada kulit dengan enam sukarelawan menunjukkan tidak terjadi iritasi pada kulit,, hasil uji stabilitas penyimpanan selama 6 siklus atau 12 hari penyimpanan pada suhu bergantian 4°C dan 40°C sediaan tetap stabil, sedangkan pada pengujian aktivitasnya terhadap Staphylococcus epidermidis pada formulasi F1 dan F2 menunjukkan hasil memiliki daya hambat dalam kategori kuat.
TINGKAT PENGETAHUAN MASYARAKAT TENTANG PENGGUNAAN OBAT ANTI HIPERTENSI DI PUSKESMAS MONCOBALANG KABUPATEN GOWA TAHUN 2022 Hamka, Zulfahmi; Syamsuddin, Yulianti
Jurnal Kesehatan Yamasi Makassar Vol. 8 No. 1 (2024): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v8i1.306

Abstract

Hipertensi adalah penyakit kronis dengan ciri tekanan darah cenderung naik turun sebagai akibatnya dibutuhkan pengobatan yang lama bahkan seumur hidup. Penelitian ini dilakukan dengan metode deskriptif. Responden pada penelitian ini adalah pasien yang berkunjung di Puskesmas Moncobalang selama penelitian berlangsung. Pengambilan sampel diperoleh dengan teknik purposive sampling yakni pengambilan sampel hanya pada individu yang didasarkan pada pertimbangan dan karakteristik tertentu. Responden pada penelitian ini sebanyak 92 orang sebagai responden. Tingkat pengetauan pasien meliputi enam dimensi yaitu pengetahuan, pemahaman, penerapan, Analisis, Sintesis dan Penilaian. Data yang diperoleh menunjukkan bahwa Tingkat Pengetahuan Masyarakat tentang Penggunaan obat anti hipertensi dengan presentase 64,68% kategori Baik.
UJI ANGKA KAPANG KHAMIR DAN ANGKA LEMPENG TOTAL PADA WEDANG UWUH YANG DIKOMBINASIKAN DENGAN BUAH MAHKOTA DEWA (Phaleria macrocarpa L.) Rusmin, Rusmin; Taufiq
Jurnal Kesehatan Yamasi Makassar Vol. 8 No. 1 (2024): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v8i1.312

Abstract

Abstrak. Penelitian ini bertujuan untuk mengetahui angka kapang khamir dan angka lempeng total pada wedang uwuh yang dikombinasikan dengan buah mahkota dewa. Desain penelitian yang digunakan adalah eksperimental laboratorium yang dilaksanakan di Laboratorium Mikrobiologi Akademi Farmasi Yamasi Makassar. Penelitian ini menggunakan wedang uwuh yang dikombinasikan dengan buah mahkota dewa yang diuji terhadap angka kapang khamir dan angka lempeng total sebagai parameter persyaratan mutu obat tradisional di Indonesia. Pengujian dilakukan selama 2 pekan yang dimana angka pencatatan angka kapang khamir dilihat pada hari ke lima, dan angka lempeng total dilihat pada hari ke tiga di setiap pekannya. Hasil penelitian menunjukkan bahwa pada uji angka kapang khamir, pekan pertama pada pengenceran 10-4 sejumlah 2 x 104, dan pada pekan kedua pengenceran 10-4 sejumlah <10. Sedangkan pada uji angka lempeng total, pekan pertama pada pengenceran 10-6 sejumlah <10, dan pada pekan kedua pengenceran 10-6 sejumlah 6 x 105. Setelah dilakukan standarisasi terhadap peraturan BPOM no 12 tahun 2014 disimpulkan bahwa sediaan wedang uwuh yang dikombinasikan dengan buah mahkota dewa aman untuk dikonsumsi pada parameter angka kapang khamir dan angka lempeng total. Kata Kunci : Wedang uwuh Mahkota dewa , Angka kapang khamir Angka lempeng total
UJI IRITASI SEDIAAN KRIM EKSTRAK ETANOL DAUN CENGKEH (Syzygium aromaticum L.) TERHADAP MENCIT (Mus musculus) Azis, Arief; Fauzan Nursyawal
Jurnal Kesehatan Yamasi Makassar Vol. 8 No. 1 (2024): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v8i1.314

Abstract

This study aims to determine the irritating effect of clove leaf ethanol extract cream (Syzygium aromaticum L.) on mice (Mus musculus) and at what concentration clove leaf extract (Syzygium aromaticum L.) can cause irritation in mice (Mus musculus). Clove leaf extract was prepared in cream preparations with a concentration of 10% and 11%. This test used a laboratory experimental method carried out at the Pharmacology Laboratory of the Yamasi Pharmacy Academy Makassar, then tested the irritating effect of Clove Leaf Extract Cream (Syzygium aromaticum L.) using the draize method on mice (Mus musculus) as test animals and observed for 24 hours,48 hours, 72 hours. Then observed the appearance of erythema and edema that occurred at each concentration of preparations in mice (Mus musculus). Based on the results of the study, it can be concluded that the ethanol extract cream of clove leaves (Syzygium aromaticum L.) at concentrations of 10% and 11% does not cause irritation.
GAMBARAN SISTEM PENYIMPANAN OBAT DI PUSKESMAS GALESONG UTARA KECAMATAN GALESONG UTARA KABUPATEN TAKALAR Muhammad Tahir, Muhammad Tahir; Mutiarah
Jurnal Kesehatan Yamasi Makassar Vol. 8 No. 1 (2024): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v8i1.315

Abstract

Research has been carried out at the North Galesong Health Center, North Galesong District, Takalar Regency to find out the description of the Drug Storage System in the Health Center. This research was conducted by direct interviews and is descriptive in nature. Apt. Hj. Kartini, S. Farm. As the Person in Charge of the Pharmacy stated that the drug storage at North Galesong Health Center had met the existing storage standards starting from the drugs being arranged alphabetically for each dosage form, the drugs being stored on the floor placed on pallets, the method of storing drugs that met the requirements such as the drugs being rotated with the FEFO (First Expired First Out) and FIFO (First In First Out) systems, liquids, ointments and injectable drugs were stored in the center of the shelf, drugs that required cold temperatures were stored in the refrigerator, there were no expired drugs in the drug store, desinfe ctan is placed separately from other drugs, drugs that have the same expiration date are used which arrive first, there are no drugs that are of poor quality, drugs that have a similar appearance and name (LASA; Look Alike Sound Alike) are not placed close together, liquid drugs are separated from solid drugs
UJI HEDONIK SEDIAAN KOSMETIK ARANG AKTIF BAMBU KUNING (Bambusa vulgaris var. Striata) Noena, Raymond Arief N; Base, Nurul Hidayah; Bayu Alfian
Jurnal Kesehatan Yamasi Makassar Vol. 8 No. 1 (2024): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v8i1.316

Abstract

Telah dilakukan penelitian yaitu Uji hedonik sediaan sabun, lulur dan pasta gigi berbahan dasar charcoal atau arang aktif bambu kuning (Bambusa vulgaris var. Striata) dengan tujuan untuk mengetahui tingkat kesukaan panelis terhadap kosmetik herbal dengan pembanding sediaan herbal sejenis yang beredar di pasaran. Uji hedonik dilakukan terhadap warna aroma, rasa, tekstur dan kemasan dan melibatkan panelis sebanyak 30 orang. Hasil penelitian menunjukkan bahwa tingkat kesukaan panelis terhadap sediaan kosmetika berturut turut sebagai berikut : pasta gigi (4,22), sabun sebesar (4,03) dan lulur (3,86) Jadi sediaan kosmetik berbahan dasar arang aktif bambu kuning memiliki potensi untuk dikembangkan menjadi sediaan kosmetik herbal modern.
AKTIVITAS SIRUP EKSTRAK KULIT BUAH RAMBUTAN (Nephelium lappaceum L.) TERHADAP KADAR KOLESTEROL TOTAL DARAH MENCIT (Mus musculus) Djajanti, Agust Dwi Djajanti; Ade Shafira
Jurnal Kesehatan Yamasi Makassar Vol. 8 No. 1 (2024): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v8i1.317

Abstract

This study aims to determine the “Activity of syrup ekstrak from Rambutan Peel (Nephelium lappaceum L.) on reducing total cholesterol levels in the blood of mice (Mus musculus).” This type of research using the pre and post test method. Induction of hypercholesterolemia was carried out by giving high-fat feed, namely duck egg yolk and butter and PTU inducers which were given every day at relatively the same time for 14 days by oral method. On the 15th day the mice were fasted but still given to drink for the next 3 hours. Cholesterol levels were measured after induction for 14 days (induction cholesterol levels). The mice test animals used were 6 mice (Mus musculus) which were divided into 2 treatment groups. On day 15, groups 1 was treated with gemfibrozil 300 mg as a positive control and group 2 was treated with syrup of rambutan peel extract. After 30 minutes, the mice’s cholesterol levels were meansured. On day 16 they were given the same treatment on day 15 and cholesterol levels were menasured 30 minutes after administration. From the results of the study it was concluded that administration of syrup of rambutan peel extract (Naphaleum lappaeum L.) with a level of 250 mg/ml can reduce total cholesterol levels in the blood of mice with an average decrease of 7% and 11%.

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