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JURNAL KESEHATAN YAMASI MAKASSAR
Published by Akademi Farmasi Yamasi Makassar
ISSN : 25488279     EISSN : 28091876     DOI : https://doi.org/10.59060/jurkes.v7i1.250
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Jurnal ini memuat naskah hasil penelitian dengan kajian ilmiah yang berkaitan dengan bidang kesehatan secara umum dan bidang farmasi khususnya. Sebuah jurnal yang didedikasikan untuk publikasi hasil penelitian seluruh aspek ilmu farmasi sebagai berikut : farmasetika, kimia farmasi, biologi farmasi, bioteknologi farmasi, serta farmakologi dan farmasi klinik, namun tak terbatas secara implisit. Jurnal ini terbit dua kali dalam setahun yaitu setiap bulan Januari dan Juli.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 265 Documents
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FORMULASI DAN UJI MUTU FISIK GRANUL EFFERVESCENT DARI TEMULAWAK (Curcuma xanthorrhiza Roxb) Rusmin
Jurnal Kesehatan Yamasi Makassar Vol 9 No 2 (2025): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v9i2.392

Abstract

Abstract. Curcuma (Curcuma xanthorrhiza Roxb) is a leading Indonesian medicinal plant that needs to be developed and utilized. Temu buffoonery contains various chemical compounds, starch is one of the most abundant ingredients found in the temu buffoonery plant. This research aims to formulate Curcuma (Curcuma xantoriza Roxb) rhizome, citric acid, tartaric acid, sodium bicarbonate, lactose, 70% alcohol and to test the physical quality of the preparation which includes organoleptic test, flow time test, soluble time test, water content test. , and the pH test resulted that the effervescent granule preparation met the physical quality requirements as a good effervescent preparation. Based on the research results, the best formula concentration data was obtained in each physical quality test of the preparation, namely formula III with a binder concentration of 6% (P <0.05), with an average flow time (9.20 seconds), dissolution time (3.46 minutes) , moisture content (0.54%), pH (6.86). This reaffirms that the research has successfully developed a granular effervescent formulation from Curcuma (Curcuma xanthorrhiza Roxb) that meets physical quality standards, especially in Formula III with a 6% binding concentration. This achievement opens up opportunities for a broader utilization of traditional Indonesian medicinal plants in a more modern and effective form. Furthermore, this finding also emphasizes the need for further research, which can focus on exploring the bioactive potential of Curcuma and further formulation innovation.
UJI AKTIVITAS SABUN MANDI HERBAL ECOENZYME SEBAGAI ANTISEPTIK ALAMI TERHADAP Staphylococcus aureus DAN Propionibacterium acne Tahir, Muhammad
Jurnal Kesehatan Yamasi Makassar Vol 9 No 2 (2025): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v9i2.393

Abstract

Evaluation of the Antiseptic Activity of Herbal Bath Soap Containing Eco Enzyme Against Staphylococcus aureus and Propionibacterium acnes. Herbal bath soap is a skin cleanser formulated with a soap base and permitted additives to enhance its functionality and consumer appeal. The use of natural ingredients, particularly fruit and vegetable waste, offers a sustainable source of active compounds. Through fermentation, these materials can be converted into eco enzyme, which contains various bioactive substances with potential antibacterial properties. This study aimed to assess the antibacterial activity of herbal bath soap formulated with eco enzyme against Staphylococcus aureus and Propionibacterium acnes. The inhibition zone assay demonstrated that soap containing 25% and 50% eco enzyme exhibited average inhibition zones of 1.596 mm and 1.69 mm against P. acnes, respectively, while the negative control produced a zone of 0.88 mm. For S. aureus, the inhibition zones at the same concentrations were 3.44 mm and 1.997 mm. These findings suggest that eco enzyme-based herbal bath soap exhibits antibacterial effects against both tested bacterial strains. However, the observed inhibition remains within the weak category (<5 mm), indicating a limited but measurable antibacterial potential.
UJI DAYA HAMBAT EKSTRAK KULIT DAGING BUAH LONTAR (Borassus flabellifer L.) TERHADAP PERTUMBUHAN Staphylococcus aureus Azis, Arief; Ismail
Jurnal Kesehatan Yamasi Makassar Vol 9 No 2 (2025): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v9i2.395

Abstract

Kulit daging buah lontar (Borassus flabellifer L) memiliki banyak kandungan Flavonoid, tanin, dan saponin yang merupakan kandungan kimia yang berkhasiat sebagai pengobatan. Penelitian ini bertujuan untuk mengetahui aktivitas ekstrak kulit daging buah lontar (Borassus flabellifer L.) terhadap Staphyloccous aureus dan menentukan konsentrasi optimal ekstrak kulit daging buah lontar Staphylococcus aureus. kulit daging buah lontar (Borassus flabellifer L.) Dibuat dalam sediaan ekstrak dengan konsentrasi 5%, 10%, 15% pengujian ini menggunakan metode eksperimental kemudian dilakukan pengujian daya hambat ekstrak kulit daging buah lontar (Borassus flabellifer L.) dengan menggunakan variasi konsentrasi 5%, 10%, 15% serta kontrol negatif menggunakan DMSO menggunakan metode paper disk dan medium agar ( NA) sebagai media dan di inkubasi selama 1 x 24 jam. Hasil penelitian menunjukkan bahwa ekstrak kulit daging buah lontar (Borassus flabellifer L.) memiliki daya hambat terhadap pertumbuhan bakteri Staphylococcus aureus. Ekstrak yang digunakan dalam tiga konsentrasi, yaitu 5%, 10%, dan 15%, menunjukkan total diameter zona hambat masing-masing sebesar 44,6 mm, 45,3 mm, dan 52 mm, dengan rata-rata zona hambat sebesar 14,8 mm, 15,1 mm, dan 17,3 mm. Seluruh hasil tersebut termasuk dalam kategori daya hambat kuat.
DISTRIBUSI PENGGUNAAN BERAGAM JENIS VAKSIN COVID-19 DI WILAYAH KERJA PUSKESMAS GENTUNGAN, DESA GENTUNGAN, KECAMATAN BAJENG BARAT, KABUPATEN GOWA TAHUN 2022 Basir, Hernawati; Yuyun Sri Wahyuni; Delvi SJP; A Tenriugi Daeng Pine; Istiana Purnamasari
Jurnal Kesehatan Yamasi Makassar Vol 9 No 2 (2025): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v9i2.396

Abstract

In December 2019, Wuhan City in Hubei Province, China, became the epicenter of a novel coronavirus outbreak, later identified as SARS-CoV-2, the causative agent of COVID-19. Common symptoms of COVID-19 infection include fever, cough, and shortness of breath. This study aimed to determine the percentage distribution of various COVID-19 vaccine types administered at the Gentungan Public Health Center. Employing a non-experimental, descriptive approach, this research analyzed existing data without intervention on test subjects, utilizing a retrospective data collection method. The study population comprised 9,000 individuals, from which a sample of 383 participants was selected. The results indicated the following distribution of vaccine usage: Sinovac was administered to 236 individuals (61.61%), Pfizer to 61 individuals (15.92%), Moderna to 53 individuals (13.83%), and AstraZeneca to 33 individuals (8.61%). Sinovac was the most frequently administered vaccine, likely due to its ample availability and the lack of choice afforded to the public regarding vaccine selection.
PEMBUATAN DAN UJI MUTU FISIK SEDIAAN FACE MIST EKSTRAK DAUN ALPUKAT (Persea americana Mill.) Sukirawati; Burhamin, Yusriyani; Nur Afifah Kamas
Jurnal Kesehatan Yamasi Makassar Vol 9 No 2 (2025): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v9i2.397

Abstract

Avocado leaves are known to contain various bioactive compounds such as flavonoids, saponins, tannins, alkaloids, and phenols that are beneficial for skin health. This study refers to several literatures indicating that avocado leaf extract (Persea americana Mill.) exhibits significant antioxidant and antibacterial activities, which is why it was used as the active ingredient in the preparation of face mist. The aim of this research was to determine the physical quality of face mist formulations made with avocado leaf extract at concentrations of 0% (F0), 5% (F1), 7.5% (F2), and 10% (F3). The study was conducted experimentally in the laboratory, where the avocado leaf extract was obtained through maceration using 96% ethanol as the solvent. Physical quality tests performed included organoleptic evaluation, homogeneity test, pH measurement, spray distribution test, drying time test, and viscosity test. The results showed that avocado leaf extract (Persea americana Mill.) can be formulated into face mist preparations at concentrations of 5%, 7.5%, and 10%, all of which met the physical quality standards for face mist products.
UJI EFEKTIVITAS GEL EKSTRAK DAUN MELINJO (Gnetum gnemon L.) TERHADAP Staphylococcus epidermidis Dzulasfi; Nur Fajrina
Jurnal Kesehatan Yamasi Makassar Vol 9 No 2 (2025): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v9i2.399

Abstract

Penelitian ini bertujuan Untuk mengetahui efektivitas sediaan gel ekstrak daun melinjo (Gnetum gnemon L.) dalam menghambat pertumbuhan bakteri Staphylococcus epidermidis dan konsentrasi optimum sediaan gel ekstrak daun melinjo dalam menghambat pertumbuhan Staphylococcus epidermidis. Daun melinjo diekstraksi menggunakan metode maserasi dengan etanol 96% dan diformulasikan menjadi sediaan gel konsentrasi 1%, 2%, dan 3%. Uji aktivitas antibakteri dilakukan dengan metode paperdisk pada media Nutrient Agar (NA) yang telah diinokulasi bakteri uji, serta menggunakan klindamisin sebagai kontrol positif dan basis gel sebagai kontrol negatif. Hasil menunjukkan bahwa gel ekstrak daun melinjo efektif dalam menghambat pertumbuhan Staphylococcus epidermidis. Dan konsentrasi optimum dari gel ekstrak daun melinjo yang dapat menghambat pertumbuhan Staphylococcus epidermidis adalah konsentrasi 3% dengan rata-rata diameter zona hambat 14,43 mm dengan kategori kuat.
AKTIVITAS TABIR SURYA EKSTRAK ETANOL DAUN Acacia auriculiformis ASAL KOLAKA MENGGUNAKAN SPEKTROFOMETRI UV-Vis Ardiansyah, Akhmad; Duppa, Muhammad Taufik; Masri, Anshari; Pratama, Andri Anugrah
Jurnal Kesehatan Yamasi Makassar Vol 9 No 2 (2025): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v9i2.401

Abstract

Excessive exposure to UV radiation can cause skin damage. Preventive measures can be taken by using sunscreen. Acacia auriculiformis is a species from the Fabaceae family, many of which are known for their antioxidant activity. Acacia auriculiformis can act as a natural sunscreen because it contains secondary metabolite compounds with conjugated double bond structures, which are known to reduce the intensity of UV exposure on the skin by absorbing ultraviolet radiation. This study aimed to identify the secondary metabolites in the ethanol extract of Acacia auriculiformis leaves from Kolaka and to determine its Sun Protection Factor (SPF) value using UV-Vis spectrophotometry. The extraction of Acacia auriculiformis leaves was carried out using the maceration method with 70% ethanol as the solvent. The sunscreen activity was determined based on the SPF values. The SPF values of the extract at concentrations of 50 ppm, 100 ppm, 150 ppm, and 200 ppm were 3.8712 (minimal protection), 6.4880 (extra protection), 9.5359 (maximum protection), and 12.5816 (maximum protection), respectively. The results indicate that sunscreen activity increases in proportion to the extract concentration. Acacia auriculiformis leaves have the potential to be developed as a sunscreen formulation.
UJI DAYA HAMBAT LOTION EKSTRAK KULIT NANAS (Ananas comosus L.) DENGAN VARIASI KONSENTRASI ASAM STEARAT DAN TRIETANOLAMIN TERHADAP Staphylococcus aureus burhamin, yusriyani; Syarifuddin KA; Sutriana
Jurnal Kesehatan Yamasi Makassar Vol 10 No 1 (2026): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/ggr9bq74

Abstract

Pineapple peel contains secondary metabolites in the form of flavonoids, saponins, and tannins. These metabolite compounds have antibacterial activity against Staphylococcus aureus. These compounds were obtained by maceration using 96% ethanol The extract obtained was then made into a lotion preparation. This study was conducted to determine the effect of varying concentrations of stearate acid and triethanolamine as emulgators of pineapple fruit peel extract lotion preparations (Ananas comosus L.) in inhibiting the growth of Staphylococcus aureus bacteria. The concentration of extract for each formula is 5%. Variation of stearic acid and triethanolain concentrations for formula I (5%; 4%), formula II (5.5%; 3.5%) and formula III (6%; 3%). The results showed that formula I, formula II and formula III had inhibition diameters that were not much different with inhibition zones of 10.21 mm, 9.72 mm and 10.13 mm respectively. Based on the results of the study, it can be concluded that variations in the concentration of stearic acid and triethanolamine in pineapple peel extract lotion preparations (Ananas comosus L.) have no effect on the inhibition of staphylococcus aureus bacteria.
KARAKTERISASI EKSTRAK KULIT UBI JALAR UNGU (Ipomea batatas L Poir) BERDASARKAN BEBERAPA PARAMETER SPESIFIK EKSTRAK Base, Nurul Hidayah; Raymond Arief N Noena; Adnan Ahmad
Jurnal Kesehatan Yamasi Makassar Vol 10 No 1 (2026): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/183x3j29

Abstract

Anthocyanin is a secondary metabolite of plants that can be used as a natural dye. Purple sweet potato (Ipomea batatas L Poir) is a food ingredient known to contain high anthocyanin compared to other types of sweet potatoes. Purple sweet potato skin which is usually not used can be used as an alternative to obtain anthocyanin as a natural dye. This study aims to determine the characteristics of purple sweet potato skin extract including extract soaking, water content, watersoluble extract content, ethanol-soluble extract content as standard parameters of extract quality. The study showed that the sweet potato skin extract produced was a thick extract, dark purple in color, slightly sweet in taste and distinctive odor, extract soaking value of 7.86% water content 15.28%, watersoluble extract content 32.82% and ethanol-soluble extract content 18.06%. 
FORMULASI  DAN KARAKTERISASI SABUN ANTISEPTIK PADAT BERBASIS MINYAK JELANTAH DIPERKAYA EKSTRAK ETANOL DAUN BIDARA CINA (Ziziphus jujuba) UNTUK PEMANFAATAN BERKELANJUTAN. Thahir, Zakiah; Yuyun Sri Wahyuni; Hernawati Basir; Istianah Purnamasari; Adrival Darwin; Aisyah; Indah Lestari
Jurnal Kesehatan Yamasi Makassar Vol 10 No 1 (2026): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/aap2gh31

Abstract

Minyak jelantah merupakan limbah rumah tangga yang berpotensi mencemari lingkungan, sementara daun bidara cina (Ziziphus jujuba) dikenal memiliki ragam aktivitas biologi, termasuk antibakteri. Pemanfaatan kedua komponen ini dalam formulasi sabun antiseptik padat dapat memberikan nilai tambah dan solusi berkelanjutan. Tujuan: Penelitian ini bertujuan untuk memformulasikan sediaan sabun antiseptik padat berbasis minyak jelantah dengan penambahan ekstrak etanol daun bidara cina yang memenuhi persyaratan mutu SNI, serta mengevaluasi karakteristik fisik, kimia, dan aktivitas antibakterinya. Metode: Minyak jelantah dimurnikan dengan arang sabut kelapa. Ekstrak etanol daun bidara cina ditambahkan ke dalam sabun pada konsentrasi 5% (F1) dan 10% (F2), dibandingkan dengan blanko (F0). Pengujian meliputi organoleptik (bentuk, warna, aroma), pH, tinggi busa, kadar air, asam lemak bebas, dan alkali bebas. Aktivitas antibakteri diuji terhadap Staphylococcus aureus, Staphylococcus epidermidis, dan Propionibacterium acne. Hasil: Semua formula sabun menunjukkan karakteristik organoleptik yang baik (padat, aroma khas) dengan variasi warna sesuai konsentrasi ekstrak. Nilai pH (9.7-10.1) dan tinggi busa (59.67-75.33 mm) memenuhi SNI. Kadar air (8.3-9.31%) dan asam lemak bebas (2.0-2.3%) juga memenuhi standar. Namun, kadar alkali bebas Formula 2 (0.2%) melebihi batas SNI (<0.1%). Semua formula dengan ekstrak menunjukkan zona hambat terhadap ketiga bakteri uji, dan zona hambat meningkat seiring peningkatan konsentrasi ekstrak (terbesar pada 10%) sehingga dapat disimpulkan bahwa  Sabun antiseptik padat berbasis minyak jelantah dan ekstrak etanol daun bidara cina berhasil diformulasikan dan memenuhi sebagian besar standar mutu SNI serta menunjukkan aktivitas antibakteri yang baik, meskipun Formula 2 memerlukan optimasi lebih lanjut terkait kadar alkali bebas.

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