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Shannaz Nadia Yusharyahya
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Journal of General Procedural Dermatology and Venereology Indonesia
Published by Universitas Indonesia
ISSN : -     EISSN : 24607991     DOI : https://doi.org/10.19100/jdvi.v1i1.8
Core Subject : Health,
Medicine & Pharmacology
Journal of General-Procedural Dermatology & Venereology Indonesia is an open access and peer-reviewed journal that focuses on dermatology and venereology. This journal publishes original articles, reviews, case reports, and brief communications which contain short features of medicine, current developments in diagnostic procedures, treatments, or other health issues that are relevant and important.
Arjuna Subject : Kedokteran - Dematologi
Articles 164 Documents
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Photodermatoses in Children Fauziah, Siti Nurani; Indriatmi, Wresti; Legiawati, Lili
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 2, No. 2
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Abstract

Photodermatoses cover the skin’s abnormal reactions to sunlight, usually to its ultraviolet (UV) component or visible light. Etiologically, photodermatoses can be classified into 4 categories: (1) immunologically mediated photodermatoses (idiopathic photodermatoses); (2) drug- or chemical-induced photosensitivity; (3) hereditary photodermatoses; and (4) photoaggravated dermatoses. The incidence of photodermatoses in the pediatric population is much lower than in adults, Polymorphous light eruption (PMLE) is the most common form of photodermatoses in children, followed by erythropoietic protoporphyria. Early diagnosis and investigations should be performed to avoid long-term complications. Photoprotection is the mainstay of photodermatoses management, including use of physical protection and sunscreen.
The comparison of skin irritation level between topical cajeput oil and telon oil: A pilot study Ilona, Sri Esa; Cahyono, Aris; Ellistasari, Endra Yustin; Irawanto, Muh. Eko; Kariosentono, Harijono
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 2, No. 3
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Abstract

Background: Cajuputi/Cajeput/Melalueca leucadendron oil is a type of essential oil, widely known and used by Indonesian for infants, children, and elderly. It is also included in telon oil compositions (±42%). Excessive application of cajeput oil and telon oil may lead to skin irritation. Methods: This randomized single-blind control trial was conducted with 10 subjects who met the inclusion criteria. Four areas with diameter of 10 mm each were made on the flexor surface of the upper arm. Area 1 was designated as negative control. Area 2 to 4 were pre-irritated with tape stripping for 40 ± 10 times using Nachitape®, followed by repeated open application test (ROAT) with cajeput oil, telon oil and alcohol (positive control). The skin irritation was examined in 15 minutes after each cycle by measuring transepidermal water loss (TEWL) using Tewameter® TM300 (Courage-Khazaka, Germany) and erythema using Mexameter® MDD4. Data were analyzed using One-way ANOVA with p<0.05 considered significance. Results: The average TEWL and erythema of cajeput oil (15.59; 345.42) were the highest compared to telon oil (12.63; 316.60), alcohol (13.87; 319.06) and negative control (7,48; 296.68). All treatment groups had significant differences in TEWL (p<0.000) and erythema (p<0.002) when compared to the negative control. However, cajeput oil showed the largest difference. Conclusion: Cajeput oil caused the most irritation compared to alcohol and telon oil. Therefore, it should be used with caution.
Non-standard patch test Adelia, Astri; Budianti, Windy Keumala; Marissa, Melani; Effendi, Evita Halim
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 2, No. 3
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Abstract

In managing contact dermatitis, identification of the causative agent is essential to prevent recurrent complaints. Patch test is the gold standard to identify the causative agent. Nowadays, there are many patch test standard materials available in the market, but do not include all the materials that potentially cause contact dermatitis. Patch test using patient’s own products or later we refer to as non-standard materials, is very helpful in identifying the causative agents of contact dermatitis. Guidance is needed in producing non-standard patch test materials in order to avoid test results discrepancy.
Occupational skin cancer and precancerous lesions Raissa, Fifinela; Rahmayunita, Githa; Menaldi, Sri Linuwih; Soemarko, Dewi
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 1, No. 3
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Abstract

Occupational skin cancer and precancerous lesions are skin disorders caused by exposure to chemical carcinogens such as polycyclic hydrocarbons and arsenic, or radiation, such as ultraviolet light and ionizing light in the workplace. Annual increase in skin cancer incidence is believed to be related to various factors such as frequent intense sunlight exposure (i.e. at work, recreational activities, and sun-tanning habit), ozone depletion, an increase in number of geriatric population, and an increase of public awareness in skin cancer. The most common occupational skin cancers are basal cell carcinoma, squamous cell carcinoma, and melanoma. Examples of occupational precancerous lesion of the skin are actinic keratosis and Bowen’s disease. Particular diagnostic criteria to diagnose occupational diseases has been developed. Early detection of occupational skin cancer and precancerous lesion is necessary. An effective prevention program consists of primary prevention such as prevention of hazardous material exposure, secondary prevention such as early detection of disease for early intervention, and tertiary prevention such as minimizing long-term impact of the disease.
Segmental zoster paresis Shihab, Nahla; Pusponegoro, Erdina HD; Yanuar, Ahmad
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 2, No. 1
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Abstract

Herpes zoster is often associated with neurological manifestation but less frequently associated with motoric nerve involvement. The most common motoric involvement is paresis, seen only in 1-5% of all zoster cases. This case report a 39-year-old male, with recurrent abdominal liposarcoma under chemotherapy, presented with symptoms of fever, and painful and weak right leg for 2 weeks. Vesicles eruption was seen on his right leg nine days after these symptoms occurred. Physical examination revealed groups of haemorrhagic vesicles with erythematous base on the right lower leg. Lumbosacral spine x-ray showed spondylosis with radiculopathy. Electromyography (EMG) examination revealed lower motor neuron total denervation corresponding to right L5 radix. The patient was diagnosed as herpes zoster on right L5-S1 segment, herpetic neuralgia, and segmental zoster paresis with recurrent liposarcoma under chemotherapy. He was treated with oral acyclovir 800 mg five times a day and gabapentin 300 mg twice a day. Physical therapy and rehabilitation were started concurrently. Paresis is a rare complication of herpes zoster. Radicular pain and weakness preceded the skin lesion potentially lead to misdiagnoses. The most frequent diagnosis for patient suffering pain and weakness in the extremities is spinal disorder, such as stenosis and disc herniation. EMG can be helpful to recognise motoric involvement of herpes zoster, and preclude other diagnoses.
Challenge in diagnosis and management of lentigo maligna and lentigo maligna melanoma Anggraini, Ika; Miranda, Elisa; Wibawa, Larisa Paramitha; Krisanti, Roro Inge Ade; Sampurna, Adhimukti T
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 2, No. 1
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Abstract

Lentigo maligna (LM) is a subtype of melanoma in situ, which can evolve into lentigo maligna melanoma (LMM) if treated inadequately. LM and LMM are usually found on chronically sun damaged skin such as the face (cheek and nose) of the elderly on seventh or eight decades. Clinical manifestation of LM may be quite subtle, so early diagnosis is difficult to perform.The treatment of LM and LMM are challenging due to ill-defined clinical margin, predilection on the face with great size, and preponderance of the elderly, which are potential for recurrency and progressiveness from LM into LMM.
Neural Leprosy: A case report Widiawaty, Alida; Sjamsoe-Daili, Emmy Soedarmi; Olivia, Taruli; Menaldi, Sri Linuwih; Marissa, Melani; Octaviana, Fitri
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 1, No. 3
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Abstract

Neural leprosy is characterized by neurological deficit without skin lesions, with a prevalence ranging from 1% to 17.7%. Diagnosis might be difficult and need a multidisciplinary approach. This is a case of axonal type motor and sensory polyradiculoneuropathy of the peripheral facial nerve. A 26-year-old woman was referred from the neurology clinic with facial paralysis, suspected as leprosy. Physical examinations were as follows: no skin lesions, left eye lagophthalmos, thickening of right lateral peroneal and bilateral posterior tibial nerves, sensory impairment, peripheral bilateral facial palsy, and wasting of bilateral distal small muscles of the hands, with normal autonomic function. Nerve Conduction Study revealed multiple demyelinating mononeuropathy of upper and lower extremities. Her serum anti-PGL-1 IgM level was 1721 μ/mL, but after three months of treatment with MDT-PB regimen, it increased to 2815μ/mL. Therefore, the treatment was switched to MDT-MB regimen and 30 mg prednisone. The patient is still undergoing treatment. There has been a slight improvement after treatment with MDT-MB regimen. Nerve biopsy is the gold standard for diagnosis but has its limitations. However, serological test of anti PGL-1 can be a marker and a useful tool as an additional test to confirm the diagnosis, especially for patients with nerve impairments. Difficulties are due to the absence of skin lesions and neuropathy which may be caused by other diseases. Both diagnosis and treatment require multidisciplinary approach. Treatment given is intended to correct nerve damage and prevent further disabilities. Click here to edit this text or paste your document here to convert it to HTML �� This demo allows you to test the features of this online HTML converter. Type in one of the fields and see the other one changing in real time! Set up the cleaning options and press ▼ Clean Work with any of the text areas and see the other one changing in real time: Left: Preview Right: Source code Preview how your document will look when published. Adjust the syntax highlighted HTML code. Check out Pranx.com for nice online pranks.
Pattern of pigmentation disorder in Cosmetic Dermatology Clinic H. Adam Malik General Hospital, Medan, 2012 - 2015 Jusuf, Nelva Karmila
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 2, No. 1
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Abstract

Background: Abnormalities of pigmentation is a cosmetic problem which affects the overall appearance of an individual. Pigmentation disorder are caused by the increase (hypermelanosis) or the decrease (hypomelanosis) amount of melanin. Objective: To determine the pattern of pigmentation disorder in Cosmetic Dermatology Clinic H. Adam Malik General Hospital Medan in 2012-2015. Methods: A retrospective study using subject's medical records from the Cosmetic Dermatology Clinic H. Adam Malik General Hospital Medan in 2012 - 2015, presented descriptively. Results: In 2012 - 2015 the number of patients who visited the Cosmetic Dermatology Clinic were respectively 210, 228, 211, 142. Hypermelanosis were found respectively in 24.76%, 16.20%, 12.79%, 5.63%. Whereas hypomelanosis were found 18.10%, 9.21%, 8.53%, 8.45%. During 2012 - 2015 melasma was the most common disorder found among hypermelanosis group, followed by post inflammatory hyperpigmentation. Meanwhile vitiligo was the only diagnosis in hypomelanosis group. Each year most of the pigmentation disorder patients came from the age group 38-48 years old except in 2015. Women were more affected than men. Conclusion: In 2012-2014, the largest proportion of pigmentation disorder were hypermelanosis, mostly melasma. In 2015, it was hypomelanosis with vitiligo as the diagnosis.
The effectiveness of laser therapy in onychomycosis patients: An evidence-based case report Prayogo, Rizky Lendl; Gaol, Evangelina Lumban; Azizah, Fitri; Lusiana, Lusiana; Rachmawati, Yenny; Rahman, Yusnita; Saldi, Siti Rizny
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 2, No. 1
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Abstract

Background: Onychomycosis may cause nail discoloration, thickening, nail bed separation, and other serious complications. For some cases, oral antifungal treatment is not tolerable because of its potential side effects and drug interactions. Laser therapy is considered as an alternative treatment, owing to the features of simple and effective, with only minor potential side effects. This EBCR was made to collect and appraise studies regarding the effectiveness of laser therapy for onychomycosis, and to suggest laser as an alternative treatment. Methods: Literature searching strategy was performed using Pubmed and Cochrane Library database to address the clinical problem. Keywords used were “laser” AND “onychomycosis”. Results: Seventy-nine articles were obtained from the search strategy procedure. After selection based on exclusion and inclusion criteria, and full-text availability, four relevant articles remained. Discussion: The study by Xu et al. was considered as the most valid study while compared to other three studies. This study used intention to treat analysis and had no loss of follow-up patients. Xu et al. compared mycological and clinical clearance rate between patients receiving laser, oral terbinafine, or combination of those two. It showed that laser therapy was less effective when compared to oral antifungal (Number Needed to Harm = 17). Conclusions: Laser has a lower level of effectiveness while compared to oral terbinafine as the current gold standard therapy for onychomycosis. However, laser therapy can still be used as an adjunctive therapy along with oral antifungal to achieve a better cure rate. More studies are needed to prove this hypothesis.
Vaginal microbiota in menopause Martinus, Martinus; Wibawa, Larisa Paramitha; Effendi, Evita Halim; Yusharyahya, Shannaz Nadia; Nilasari, Hanny; Indriatmi, Wresti
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 1, No. 3
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Abstract

The human vagina together with its resident, microbiota, comprise a dynamic ecosystem. Normal microbiota is dominated by Lactobacillus species, and pathogen microbiota such as Gardnerella species and Bacteroides species can occur due to decrease in Lactobacillus domination. Lactobacillus plays an essential role in keeping normal vaginal microbiota in balance. Vaginal microbiota adapts to pH change and hormonal value. Changes in the vaginal microbiota over a woman’s lifespan will influence the colonization of pathogenic microbes. They include changes in child, puberty, reproductive state, menopause, and postmenopause. Estrogen levels change will affect the colonization of pathogenic microbium, leading to genitourinary syndrome of menopause. Vulvovaginal atrophy is often found in postmenopausal women, and dominated by L. iners, Anaerococcus sp, Peptoniphilus sp, Prevotella sp, and Streptococcus sp. The normal vaginal microbiota’s imbalance in menopause will cause diseases such as bacterial vaginosis, and recurrent vulvovaginal candidiasis due to hormonal therapies. Changes in the vaginal microbiota due to bacterial vaginosis are characterized by decrease in H2O2-producing Lactobacillus. They are also caused by the increase in numbers and concentration of Gardnerella vaginalis, Mycoplasma hominis, and other anaerob species such as Peptostreptococci, Prevotella spp, and Mobiluncus spp.

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