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Journal of Pharmaceutical and Sciences.
Published by Universitas Tjut Nyak Dhien
ISSN : -     EISSN : 26563088     DOI : https://doi.org/10.36490/journal-jps.com
Core Subject : Health, Science, Agriculture, Engineering,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health
Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, Medicinal Chemistry, Molecular Pharmacology, Novel drug delivery system, Nanotechnology, Analytical Chemistry, Organic Chemistry, Natural Chemistry, Polymer Sciences, Clinical Pharmacy, pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, government policies related to pharmacy, pharmaceutical care, Medical Biotechnology, Biochemistry, food chemistry, health and applied sciences relevant to the field of pharmacy. Journal of Pharmaceutical and Sciences (JPS) accepts manuscripts in Indonesian Language (Bahasa Indonesia) with titles and abstracts in bilingual, both Indonesian and English. We accept article manuscripts in the form of original research, literature reviews, and systematic reviews. We do not accept articles in the form of case reports
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 654 Documents
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Pengaruh EMO DEMO Pemberian Makan Bayi Dan Anak (PMBA) Terhadap Peningkatan Pengetahuan Ibu Sebagai Upaya Pencegahan Stunting Pada Balita Di Posyandu Rangkaian Melati Yulita, Yulita; Jairani, Eka Nenni; Nababan, Agnes Sry Vera
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 4 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i4.610

Abstract

The problem of stunting does not only occur in Indonesia, but is also a global issue. The high rate of stunting in children under 5 years of age requires serious attention because it can affect their growth and development. Infant and young child feeding practices (PMBA) have great benefits in preventing stunting and supporting optimal growth and development processes. Inappropriate feeding in infants and toddlers can be one of the factors causing growth and development disorders known as stunting. This study aims to determine the effect of infant and young child feeding through emo-demo as an effort to prevent stunting in toddlers. The type of research is a quasi-experiment, with a one-group pretest-posttest design with a sample size of 30 mothers of toddlers. The results showed that there was an increase in the median score of maternal knowledge before and after being given an emo demo with a P-value of 0.000. The conclusion is that there is an effect of the emo demo about MP-ASI on changes in maternal knowledge before and after being given an emo demo at Posyandu.
Pengaruh Konsumsi Air Kelapa Hijau Terhadap Penurunan Nyeri Disminorhea Pada Siswi Di SMA PAB 6 Helvetia Medan Tahun 2022 Marlina, Marlina; Pratiwi , Debby; Mouliza, Nurul
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 4 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i4.611

Abstract

The problem of menstrual pain is the problem most often complained of when women come to the doctor regarding menstruation. Menstrual pain can attack women who menstruate at any age. There is no age limit, and it is often accompanied by aggravating conditions such as dizziness, cold sweats, and even fainting. The research aimed to determine how giving young green coconut water reduces dysmenorrhea pain in adolescents. This research method uses a pre-experimental design using a one-group pre-test post-test approach. The research population was 40 people, and a quota sampling technique was used. The population in this study was young people, and the sample size was 17 respondents. Based on the results of statistical tests using the Wilcoxon test, the Asymp.The sig (2-tailed) value was 0.00; this value is smaller than the alpha (α) value of 0.05. so it can be concluded that Ha is accepted and Ho is rejected, so it can be concluded that there is a significant effect before and after being given a drink of young green coconut water on reducing dysmenorrhea pain. The results of this study concluded that young green coconut water had a significant effect on lowering dysmenorrhea pain.
Pengaruh Resiliensi terhadap Psychological Well-Being Pada Mahasiswa Program Pertukaran Mahasiswa Merdeka (PMM2) Di Institut Kesehatan Helvetia Tahun 2022 Tarigan , Rahmawati; Chairunisa , Milna; Afriani , Miskah
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 4 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i4.612

Abstract

When a change occurs unexpectedly, a person must adapt to unpleasant conditions and find a way out of the problems experienced. These changes certainly affect the psychological condition of students who move from one province to another and temporarily change their place of study. This study was conducted to obtain a picture of the resilience and psychological well-being of students in the Independent Student Exchange Program (PMM2) at the Helvetia Health Institute in 2022 in facing different situations, such as different lecture systems and cultures from their home areas, and whether there is an influence between resilience and the psychological well-being of students in the Independent Student Exchange Program (PMM2) at the Helvetia Health Institute in 2022. This study uses a quantitative approach. The research participants were 30 Independent Student Exchange Program (PMM2) students. Data was collected using two scales, namely the resilience and psychological well-being questionnaires. Data analysis was carried out using a simple linear regression test.
Komunikasi Terapeutik Dalam Meningkatkan Pelayanan Keperawatan di RS. Mitra Medika Tanjung Mulia Asrul, Asrul; Afriani , Miskah
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 4 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i4.613

Abstract

Through communication, relationships, and trust can be established between individuals. Communication plays a significant role, as every human has the inherent ability to communicate, even if methods vary widely. This is equally true for the demands of the nursing profession. Nurses are not only required to possess medical and health knowledge but must also demonstrate communication skills that are clear, effective, and purposeful. Additionally, nurses must maintain a high moral responsibility in their communication, characterized by empathy, compassion, and a willingness to assist.  This study aims to enhance the quality of nurse services in hospitals, particularly in addressing the diverse characteristics and physical or psychological conditions of patients, demanding effective communication skills to accurately understand and meet patient needs. Communication challenges among nurses present a serious issue, as poor communication can negatively impact patients’ comfort and, ultimately, their healing process.  This study utilizes an experimental method with a one-group pretest-posttest design. This design allows for the comparison of results before and after an intervention, helping to measure the impact of the treatment. The population includes all 266 inpatient nurses at Mitra Medika Tanjung Mulia Hospital in Medan, with a purposive sample of 59 nurses. Data analysis was conducted using paired t-tests. Results indicate that therapeutic communication plays a critical role in supporting patient recovery. To achieve this, nurses must continuously improve their knowledge and therapeutic communication skills within their clinical practice.
Optimasi Sediaan Serum Antiaging Ekstrak Etanol Rambut Baby Corn (Zea mays L.) Dwi Septyani, Vika Rizky; Wicahyo , Septian Maulid; Raharjo , Danang
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 4 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i4.622

Abstract

Skin is one of the organs that serve to protect the body from external influences. Exposure to free radicals causes skin damage, so antioxidant compounds are needed. Baby corn (Zea mays L.) hair contains flavonoids that have the potential to be antioxidants so that they can be formulated into an optimum serum preparation. This experimental study aims to determine the optimal formula concentration and antioxidant activity of anti-aging serum preparation of ethanol extract of Hair (Zea Mays L.). The optimum formula was obtained from the data analysis of Design Expert 13 Simplex Lattice Design method with variations in the concentration of Karbopol and TEA. The results showed that the variation of Karbopol and TEA concentrations affected the physical quality evaluation. The desirability value was 0.903, and the optimum formula concentration was obtained at Karbopol 1.7795% and TEA I2.294%. Data analysis of the optimum formula using the Shapiro-Wilk Normality Test and One Sample T-Test Test resulted in normally distributed data and no significant difference with the predicted value. The antioxidant activity test result of the optimum formula was 65.08 μg/ml with a strong category.
Uji aktivitas antioksidan ekstrak etanol daun benalu Helixanthera cylindrica (Jack) Danser pada tumbuhan kelor (Moringa oleifera) dengan metode 2,2-diphenyl-1-picrylhydrazyl Potalangi, Nerni Olvi; Palandi, Reky Royke; Manoppo, Amalia J.; Tewu, Tewsi M.; Kanter, Jabes Wolter; Sambou, Christel Nataniel
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 4 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i4.626

Abstract

Free radicals can originate from within the human body as a result of metabolic processes from chemical reactions in the body, as well as from external sources or the environment, including emissions from motor vehicles, air pollution from factories, industrial chemicals, food and beverage substances, cigarette smoke, radiation, and sunlight. Antioxidants are components that can prevent cells or molecules from being oxidised by donating electrons or hydrogen atoms to free radicals. The impact of the reactivity of free radical compounds can result in cell or tissue damage, degenerative diseases, and even cancer. One of the parasites on the moringa plant, namely Helixanthera cylindrica (Jack) Danser, contains secondary metabolite compounds such as alkaloids, flavonoids, and saponins. This research aimed to determine whether the leaves of the Helixanthera cylindrica (Jack) Danser mistletoe have antioxidant activity using the 2,2-Diphenyl-1-Picrylhydrazyl (DPPH) method. The research method is a laboratory experiment with five concentrations and three repetitions. Subsequently, the antioxidant activity testing is conducted qualitatively using the DPPH method at a wavelength of 517 nm and utilising a Spectrophotometer UV-Vis. Based on the results of the antioxidant test, the extract of Helixanthera cylindrica (Jack) Danser leaves has extreme activity with an IC50 value of 28.74 ppm. In contrast, the comparison, vitamin C has an IC50 value of 1.57 ppm. The regression equation for the concentration of the mistletoe is y=0.3344x + 40.389 with an R2 value of 0.9726, and Vitamin C shows y=4.4065x + 43.079 with an R² value of 0.9677. It can be concluded that the leaves of Helixanthera cylindrica (Jack) Danser on the Moringa oleifera plant have extreme antioxidant activity.
Uji aktivitas antipiretik ekstrak etanol daun kembang merak (Caesalpinia pulcherrima (L.) terhadap mencit jantan (Mus musculus) yang diinduksi vaksin DPT-HB Handayana, Icha; Mambang, D. Elysa Putri; Nasution , M. Pandapotan; Rahayu , Yayuk Putri
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 4 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i4.627

Abstract

Peacock flower leaves are an ornamental plant Indonesian people use to decorate their yards. Peacock flower leaves contain alkaloids, saponins, tannins, glycosides, and calcium oxalate. Peacock flower leaves are often used as an antipyretic, antibacterial, and liver inflammation. Fever is common in children and adults. The use of paracetamol at this time is usually found in the community, but the use of paracetamol has adverse side effects. The research aims to determine the antipyretic activity of the ethanol extract of peacock flower leaves. This study was experimental; the research method was carried out by screening phytochemicals and administering a suspension of peacock flower leaf extract given orally at a dose of 50,100,200mg/kg in male mice induced with DPT-HB. Paracetamol was used as a comparison, and then the body temperature of the mice was measured using a thermometer every 30 minutes for 3 hours (180 minutes) rectally. Data were analysed using SPSS ver.24 One Way ANOVA and continued with the Tukey test. The results of the phytochemical screening of simplicia powders and extracts contained secondary metabolites of alkaloids, flavonoids, tannins, saponins, triterpenoids/steroids and glycosides. The antipyretic activity obtained in each treatment significantly affected the One-way ANOVA and Tukey test results with a P <0.05. The results showed that peacock flower leaf extract had antipyretic activity, and the greatest antipyretic activity was at a dose of 100mg/kg BW with a very significant difference with 1% Paracetamol. It can be concluded that peacock flower leaf extract has the most effective antipyretic activity at a dose of 100mg/kg BB.
Camilan fungsional sus khi-yam: uji organoleptik dan kimia produk sus kering kacang hijau dan bayam untuk pencegahan anemia Jairani, Eka Nenni; Fatahillah , Sudana; Sari , Dini Novita
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 4 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i4.628

Abstract

Background: Anemia is when the hemoglobin levels in the blood are lower than the normal range. Anemia can be prevented by consuming foods that are high in protein, iron, and vitamin C. Mung beans (Vigna Radiata) and green spinach (Amaranthus hybridus L.) are foods rich in iron and vitamin C so that they can help hemoglobin formation. Dry Eclairs is a snack enjoyed by all age groups. Adding mung bean flour and spinach flour to prepare dry eclairs aims to make it a healthy snack to prevent anemia. Objectives: The research seeks to determine the organoleptic and chemical test results of dried éclair with mung beans and spinach (Sus Khi-Yam). Methods: The research method used a completely randomized design (CRD) experiment with three treatments (F1, F2, and F3) and two repetitions, resulting in 6 experimental units. The Organoleptic test was conducted with 40 untrained panelists. The Chemical analysis was carried out to determine the levels of iron, antioxidants, vitamin C, fiber, and ash. Results: The organoleptic test showed that the most preferred color by the panelists was in treatment F1, with a preference level of 3.55. For flavor, treatment F2 was the most preferred by the panelists, with a preference level of 3.40. The most preferred taste was also found in the F2 treatment, with a score of 3.50. Meanwhile, the texture of the three treatments did not show significant differences in panelist preference. The Chemical test indicated that the F2 treatment had higher fiber, iron, and antioxidant content than other treatments. Conclusion: Panelist acceptance of Sus Khi-Yam snacks for all treatments (F1, F2, and F3) is acceptable, but the best Sus Khi-Yam snacks according to panelists in terms of color are in F1 treatment, the best Sus Khi-Yam snacks according to panelists in terms of texture are in F3 treatment and the best Sus Khi-Yam snacks according to panelists in terms of taste and aroma are in F2 treatment.
Antibakteri infusa akar mangrove Sonneratia alba pada Escherichia coli dan Staphylococcus aureus Tuda , Aletheia Marvla Windi; Mongi, Jeane; Kanter , Jabes W.; Pareta , Douglas; Ginting , Amal; Hariyadi, Hariyadi
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 4 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i4.636

Abstract

Antibacterial is a substance that stops and kills the growth of bacteria. Mangrove Sonneratia alba is an exciting plant to use as a medicine because of its antibacterial properties. Secondary metabolite compounds such as alkaloids, phenols, tannins, saponins, triterpenoids, and flavonoids present in the roots are antimicrobial. This study aims to determine the antibacterial activity of mangrove root infusion of Sonneratia alba in Staphylococcus aureus and Escherichia coli. This laboratory study uses the agar diffusion technique with a well to test antibacterial. Using three concentrations, namely 25%, 50%, and 100%, this study found that the infusion of the roots of the Sonneratia alba mangrove 25%, 50%, and 100% showed antibacterial activity against Escherichia coli and Staphylococcus aureus bacteria. The results of the Kruskal-Wallis test showed that Escherichia coli bacteria showed a P value of 0.010<0.05 and Staphylococcus aureus bacteria with a P value of 0.011<0.05, which showed that there was a significant difference between the two types of bacteria because the significant value was less than 0.05.
Skrining fitokimia dan uji aktivitas antiinflamasi ekstrak akar Sonneratia alba terhadap luka bakar pada tikus (Rattus norvegicus): Indonesia Mongi, Jeane; Karauwan, Ferdy A.; Tuda, Aletheia
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 4 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i4.639

Abstract

Burns caused by inflammation can lead to severe and potentially fatal conditions, especially if the burn is located in a very sensitive area of the body or if the burn becomes infected. Untreated inflammation can cause very severe inflammation, which can damage cells, tissues, or organs. The roots of Sonneratia alba contain alkaloids, flavonoids, saponins, triterpenoids, and tannins that can help heal burns. The aim of this research is to determine the phytochemistry and the effects of the ethanolic extract of Sonneratia alba roots on the healing of burn wounds on rat skin. Research Method: The research uses an experimental method. The research includes the extraction stage, using 96% ethanol as a solvent in the maceration process, and the ethanol extract of S. alba roots is screened for its chemical content. Testing phase of the anti-inflammatory activity of Sonneratia alba mangrove root extract on burn wound healing. Experimental animals used were 15 Rattus norvegicus rats divided into 5 groups with different concentrations of 3 treatments, that is: the positive control group with Bioplacenton gel, the negative control group with Aquadest, the group with 15% ethanol extract of S. alba root, the group with 30% ethanol extract of S. alba root, and the group with 45% ethanol extract of S. alba root. During the observation phase, the measurement of burn healing diameter was conducted over 32 days using callipers. The research result show that the ethanol extract of Sonneratia alba roots contains alkaloids, flavonoids, saponins, tannins, triterpenoids, and phenolic compounds. The 15%, 30%, and 45% concentrations of the ethanol extract of Sonneratia alba roots have the potential to heal burns in rats. Ethanolic root extract showed an increase in healing power after the 20th day, faster than Biopalcenton gel.

Page 35 of 66 | Total Record : 654

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