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Journal of Pharmaceutical Science and Herbal Technology
Published by STIKES Nani Hasanuddin Makassar
ISSN : 25281534     EISSN : 26860449     DOI : 10.35892/jpsht.v1i1
Core Subject : Health, Science,
Immunology & microbiology Medicine & Pharmacology
Jurnal Ilmu Kefarmasian dan Tekhnologi Herbal (Journal Of Pharmaceutical Science And Herbal Technology) P-ISSN: 2528-1534; E-ISSN: 2686-0449 terbit dalam dua kali setahun yakni pada bulan Februari dan Agustus. Jurnal ini merupakan jurnal resmi yang diterbitkan oleh STIKES Nani Hasanuddin dan diunduh secara daring (open acces journal). Jurnal ini merupakan publikasi yang focus pada penelitian ilmu farmasi dan tekhnologi herbal termasuk farmakologi, farmasetika, kimia farmasi, pelayanan kefarmasian, dan herbal medicine. Aksesibilitas. Jurnal ini menawarkan akses terbuka, yang berarti siapa pun dapat dengan bebas mengakses artikel-artikelnya. Hal ini sangat penting untuk menyebarluaskan berbagi pengetahuan dan melakukan penelitian kepada khalayak yang lebih luas.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 54 Documents
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UJI AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL TUNAS REBUNG (Bambusa SP) PADA KAKI TIKUS WISTAR JANTAN YANG DIINDUKSI KARAGENAN Muhammad Asri SR; Winarni; Nielma Auliah; Nurjannah Bachri
Journal of Pharmaceutical Science and Herbal Technology Vol. 8 No. 2 (2023): Journal of Pharmaceutical Science and Herbal Technology
Publisher : STIKES Nani Hasanuddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35892/jpsht.v1i1.1455

Abstract

Penelitian ini bertujuan untuk mengetahui apakah ekstrak etanol tunas rubung (Bambusa SP) memiliki aktivitas sebagai antiinflamasi pada tikus Jantan galur wistar dan berapa konsentrasi yang paling efektif dari ekstrak etanol tunas rebung (Bambusa SP) yang memberikan aktivitas antiinflamasi yang dilihat dari dari parameter penurunan edema pada kaki tikus. Metode penelitian secara eksperimental dengan cara tikus putih Jantan galur wistar sebanyak 15 ekor diinduksi dengan karagenan yang dibagi menjadi 5 kelompok, masing-masing kelompok terdiri dari 3 ekor. Kelompok control negatif diberikan Na-CMC dan control positif diberikan natrium diklofenak. Kelompok I diberikan ekstrak dengan konsentrasi 2%, kelompok II diberikan ekstrak dengan konsentrasi 4% dan untuk kelompok III diberikan ekstrak dengan konsentrasi 6%. Hasil penelitian menunjukkan bahwa : 1. Efek antiinflamasi dari ekstrak tunas rebung sangat kuat 2. Pemberian ekstrak etanol tunas rebung (Bambusa SP) berpengaruh terhadap penurunan edema pada kaki tikus Jantan galur wistar 2. Ada perbedaan pengaruh pemberiaan dosis terhadap penurunan edema pada kaki tikus Jantan galur wistar.
SKRINING FITOKIMIA EKSTRAK METANOL DAUN PANDAN WANGI (Pandanus amarillyfolius Roxb) Rahmasiahi; Shabran Hadiq; Tika Yulianti
Journal of Pharmaceutical Science and Herbal Technology Vol. 8 No. 2 (2023): Journal of Pharmaceutical Science and Herbal Technology
Publisher : STIKES Nani Hasanuddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35892/jpsht.v1i1.1456

Abstract

Daun pandan wangi memiliki banyak manfaat yang secara empiris dikenal di kalangan penduduk sekitar sebagai pengawet makanan, pewarna alami, pewangi, pencerah rambut, dan obat tradisional untuk berbagai penyakit. Penelitian ini bertujuan untuk mengetahui adanya senyawa fIavonoid, saponin, tanin, triterpenoid/steroid, aIkaIoid, gIikosida, dan minyak atsiri pada ekstrak metanoI daun Pandan Wangi (Pandanus amaryIIifoIius Roxb) di Kabupaten Sidrap. Penelitian ini merupakan penelitian eksperimental pada proses ekstraksi dilakukan dengan metode maserasi menggunakan pelarut metanol dan dilanjutkan dengan skrining fitokimia. Hasil penelitian menunjukkan bahwa ekstrak metanol daun pandan wangi mengandung senyawa flavonoid, saponin, tanin, triterpenoid, alkaloid, glikosida, minyak atsiri dan negative mengandung steroid. Berdasarkan penelitian yang telah dilakukan, maka dapat disimpulkan bahwa uji skrining fitokimia ekstrak metanol daun pandan wangi (Pandanus amaryllifolius Roxb) mengandung senyawa flavonoid, saponin, tanin, triterpenoid, alkaloid, glikosida dan minyak atsiri sedangkan senyawa steroid negatif mengandung senyawa, hal ini dapat disebabkan oleh lingkungan tempat tumbuh, unsur hara, ketinggian, suhu, kelembapan udara, intensitas cahaya dan pH tanah.
PEMANFAATAN EKSTRAK BIJI PEPAYA (Carica papaya L) SEBAGAI ANTIACNE DALAM BENTUK SEDIAAN MASKER PEEL-OFF Fitriani Fajri Ahmad; Jangga; Hasnaeni
Journal of Pharmaceutical Science and Herbal Technology Vol. 8 No. 2 (2023): Journal of Pharmaceutical Science and Herbal Technology
Publisher : STIKES Nani Hasanuddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35892/jpsht.v1i1.1457

Abstract

Selama ini Biji Pepaya (Carica papaya L) dianggap sebagai limbah karena tak memiliki daya guna. Namun sebagai bagian dari produk alam, komponen dalam biji pepaya juga mengandung senyawa metabolit sekunder yang memiliki efek antibakteri. Dalam upaya memperkaya sumber bahan baku dari alam, telah dilakukan penelitian pemanfaatan ekstrak biji pepaya sebagai antiacne dalam bentuk sediaan masker Peel-Off. Penelitian ini bertujuan untuk mendapatkan konsentrasi optimum ekstrak biji pepaya yang efektif menghambat bakteri Propionibacterium acnes. Biji pepaya diektraksi dengan metode maserasi menggunakan pelarut etanol 96%. Formulasi masker Peel-Off menggunakan basis HPMC dengan konsentrasi ekstrak biji pepaya 10, 15 dan 20%. Formulasi tersebut diuji kestabilannya dengan uji Cycling test selama 6 siklus. Konsentrasi optimum ekstrak biji pepaya yang dapat menghambat bakteri Propionibacterium acnes dilakukan dengan metode sumuran. Data penelitian dianalisis secara statistic uji One-way ANOVA. Hasil penelitian ini menunjukkan bahwa sediaan masker Peel-Off dengan konsentrasi 10 % efektif menghambat bakteri Propionibacterium acnes.
THE EFFECT OF COMBINATION MENIRAN ROOT (Phylanthus niruri L.) AND JAVA ACID LEAVES (Tamarindus indica L.) on ALOKSAN-INDUCED DARNESS GLUCOSA RATS (Rattus norvegicus) Asri SR, Muhammad; Gisela; Muzayyidah
Journal of Pharmaceutical Science and Herbal Technology Vol. 9 No. 1 (2024): Journal of Pharmaceutical Science and Herbal Technology
Publisher : STIKES Nani Hasanuddin Makassar

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Abstract

Meniran root (Phylanthus niruri L.) and tamarind (Tamarindus indica L.) have flavonoid compounds that function to repair pancreatic tissue damage caused by DNA alkyl groups from alloxan induction. This study aims to determine the activity of a combination of meniran root extract (Phylanthus niruri L.) and tamarind leaves (Tamarindus indica L.) on blood glucose levels of male rats (Rattus norvegicus) induced by alloxan. This study was carried out experimentally. White rats up to 15 heads were divided into 5 groups. Alloxan induction at a dose of 125 mg/kgBB intraperitoneally to cause pancreatic damage was performed in 5 treatment groups. Three treatment groups were treated with different doses of a combination of meniran and tamarind root extracts, (P1) 7.5 mg/KgBB, (P2) 10 mg/KgBB and (P3) 15 mg/KgBB, one group as negative control (K-) was given 1% Na CMC and positive control (K+) was given 5 mg glibenclamide. The combination of meniran root extract (Phylanthus niruri L.) and tamarind leaf (Tamarindus indica L.) was given for 1 day. Glucose levels were checked after 2 hours, 4 hours, 6 hours and 24 hours of administration. The results showed that the three concentrations of a combination of meniran root extract (Phylanthus niruri L.) and tamarind leaf (Tamarindus indica L.) can reduce the blood glucose levels of male rats (Rattus norvegicus) induced by alloxan.
FORMULATION OF ANTI-ACNE MASK OF PAPAYA LEAF EXTRACT (Carica papaya L.) AND HONEY AGAINST Propionibacterium acn Wali, Putri; Asri SR, Muhammad; Sadsyam, Sriyanty
Journal of Pharmaceutical Science and Herbal Technology Vol. 9 No. 1 (2024): Journal of Pharmaceutical Science and Herbal Technology
Publisher : STIKES Nani Hasanuddin Makassar

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Abstract

Papaya leaves (Carica papaya L.) are ornamental plants that are very useful because they contain alkaloids, flavonoids, saponins, tannins and terpenoids. The alkaloids here have antibacterial properties. Honey is usually used as an antibacterial. Apart from being an antibacterial, honey is also an antioxidant because honey contains vitamin C. Acne (Acne vulgaris) is a skin disease caused by chronic inflammation with a complex pathogenesis, involving the sebaceous glands caused by the bacteria Propiobacerium acne. This research aims to determine whether the anti-acne mask formulation of papaya leaf extract and honey is physically and chemically stable and that the anti-acne mask formulation of papaya leaf extract and honey has anti-acne activity against Propionibacterium acne. This research is an experimental laboratory using the diffusion technique so that the well method is used to determine the diameter of the inhibition zone and for data analysis using the one-way ANOVA test. The results of research on the formulation of an anti-acne mask from papaya leaf extract and honey are physically and chemically stable. The anti-acne mask formulation of papaya leaf and honey extract has antibacterial activity against Propionibacterium acne with an inhibition zone of 17.2 mm (strong) in formulation 1, 19.6 mm (strong) in formulation 2, 19.8 (strong) in formulation 3 and 21.9 mm (very strong) on ​​the positive cotrol, namely benzolac (Benzolic peroxide).
FORMULATION OF LIP TINT FROM EXTRACTS OF KEPOK BANANA FLOWER (Musa paradisiaca Linn.) AND DRAGONFRUIT (Hylocereus polyrhizus) AS NATURAL COLOURS Sudirman, Agriawan; Asri SR, Muhammad; Dahlia
Journal of Pharmaceutical Science and Herbal Technology Vol. 9 No. 1 (2024): Journal of Pharmaceutical Science and Herbal Technology
Publisher : STIKES Nani Hasanuddin Makassar

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Abstract

Lip tint is a cosmetic preparation used to color lips which has liquid texture with a more natural color so that it is easily absorbed and produces a natural color like the lips’ original color. This research aimed to determine whether kepok banana flower peel extract (Musa paradisiaca Linn.) and dragon fruit (Hylocereus polyrhizus) can be formulated in the from of lip tint preparations as natural dyes and to test the antioxidant activity of lip tint preparations. The research method was experimental research by making lip tint formulations with concentrations of FI (2%), FII (6%), and FIII (10%) from banana peel and dragon fruit extracts, evaluating the preparations using physicochemical methods and testing antioxidant activity using the method DPPH using a UV-Vis spectrophotometer. The results showed that the total anthocyanin content in the peel of the kepok banana flower was 0,374 mg/L and in dragon fruit it was 8,232 mg/L. Lip tint preparation formulas with concentrations of 2%, 6% and 10% are physically and chemically stable and the antioxidant activity test in Formula I (2%) obtained an IC50 value of 3,52 µg/mL, Formula II (6%) obtained an IC50 value of 3,91 µg/mL, Formula III (10%) obtained an IC50 value of 1,62 µg/mL and in the positive control comparison (Lip Tint Implora®) an IC50 value of 1,98 µg/mL was obtained. The formula with a concentration of 10% has an IC50 value of 1,62 µg/mL in the very strong category.
FORMULATION OF BRIGHTENING GEL WITH ETANOL EXTRACT OF RED PAWPAW LEAVES (Syzygium oleana) AS ANTIOXIDANT Suryanita; Alfiani Am, Fenni; Asri SR, Muhammad; junita, Nurfitria
Journal of Pharmaceutical Science and Herbal Technology Vol. 9 No. 1 (2024): Journal of Pharmaceutical Science and Herbal Technology
Publisher : STIKES Nani Hasanuddin Makassar

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Abstract

Excessive sun exposure can have a negative impack on the skin. One way that can be done to reduce this impact is to use sunscreen. This research aimed to determine whether the ethanol of red shoot leaves (Syzygium oleana) can be formulated into a gel preparation that is physically and chemically stable and to determine sunscreen activity based on the SPF value using the UV-VIS spectrophotometric method. The method in this research was laboratory experimental. Red shoot leaves were extracted by using the maceration method with a preparation formula designe in three concentration, namely Formula 1 (1%), Formula 2 (3%),and  Formula 3 (5%). Then a stability test was carried out by storing at temperatures of 40C and 400C. Evaluation of preparation qualityincludes organoleptic, homogeneity, pH, viscosity, and spreadability test. An SPF value test was also carried out. The research results that have been carried out show that the ethanol extract of red shoot leaves with concentration of 1% 3% and 5% formulated in gel form produces a stable preparation and meets the quality requirements of the preparation. The SPF value from formula 1 is 2,508349 (minimal protection), formula 2 3,380475 (minimal protection) and formula 3 2,679704 (minimal protection).
THE COMMUNITY KNOWLEDGE ON USE OF TRADITIONAL MEDICINE FOR SELF-MEDICATION IN MANGNGI HAMLET, NOSU SUB-DISTRICT Indrayani, Ferna; Muin, Rahmatullah; Datu, Jumiati
Journal of Pharmaceutical Science and Herbal Technology Vol. 9 No. 1 (2024): Journal of Pharmaceutical Science and Herbal Technology
Publisher : STIKES Nani Hasanuddin Makassar

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Abstract

Traditional medicines are ingredients or ingredients in the form of plants, animals, minerals, galenic preparations or mixtures of various ingredients that have been used for generations as medicine and can be used by the community in accordance with applicable norms. Self-medication or self-medication is an attempt by the community to treat complaints or symptoms of illness on their own without the help of medical personnel. This study aims to determine the description of public knowledge about the use of traditional medicine as self-medication in Mangngi' Hamlet, Nosu District. The type of research used is descriptive research. The research was conducted on June 20-22 2023 for respondents who live in Dusun Mangngi' with the number of respondents using a questionnaire. The description of the use of traditional medicine as self-medication in Dusun Mangngi' is that people who know well (94.74%) and less (5.26%).
THE FORMULATION OF CREAM PREPARATIONS BLUSH ON OF ETANOL EXTRACT FROM MIANA PURPLE LEAVES (Coleus scutellarioides L.) AS BLUSHER Suryanita; Fitrahmia S, Nur; Auliah, Nielma; Bachri, Nurjannah
Journal of Pharmaceutical Science and Herbal Technology Vol. 9 No. 1 (2024): Journal of Pharmaceutical Science and Herbal Technology
Publisher : STIKES Nani Hasanuddin Makassar

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Abstract

Anthocyanin is a chemical compound found in purple miana leaves and plays an important role in providing color. Purple miana leaf extract can be used as a natural coloring in blush on cream preparations. The aim of this research is to determine whether purple miana leaf extract (Coleus scutellarioides L) can be formulated in the form of a blush cream dosage form that is physically and chemically stable. The research method used was experimental research by making blush on preparation formulations with concentrations of 7.5%, 10% and 12.5% ​​and evaluating the preparations using physicochemical, irritation tests and hedonic tests. The research results showed that blush on formulations with concentrations of 7.5%, 10% and 12.5% ​​were physically and chemically stable and in the hedonic/preference test the most preferred formulation was the formulation with a concentration of 12.5%. The conclusion of this research is that the ethanol extract of purple miana leaves (Coleus Scutellarioides L) can be formulated in the form of a blush cream dosage form that is physically and chemically stable.
UJI AKTIVITAS ANTIHIPERGLIKEMIA EKSTRAK DAUN JAGUNG MANIS (ZEA MAYS SACCHARATA) PADA MENCIT (MUS MUSCULUS) DIINDUKSI SUKROSA Rahimah, Sitti; Hasmita, Nur
Journal of Pharmaceutical Science and Herbal Technology Vol. 9 No. 2 (2024): Journal of Pharmaceutical Science and Herbal Technology
Publisher : STIKES Nani Hasanuddin Makassar

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Abstract

Pendahuluan: Kejadian penyakit degeneratif seperti diabetes melitus semakin meningkat seiring perubahan pola hidup dan lingkungan. Pengobatan DM perlu diperhatikan, karena penderitanya memerlukan pengobatan sepanjang hidup untuk mengurangi gejala, mencegah progresivitas penyakit dan mencegah terjadi komplikasi. Jagung merupakan salah satu tumbuhan yang digunakan oleh masyarakat sebagai obat tradisional Salah satu bagian dari jagung yang biasanya hanya dianggap sebagai limbah dan dapat digunakan sebagai antidiabetes yaitu daun jagung. Tujuan penelitian: Penelitian dilakukan untuk mengetahui aktivitas dari ektrak daun jagung manis sebagai antihiperglikemia pada hewan coba yang diinduksi sukrosa. Metode penelitian:Penelitian ini dilakukan dengan mengelompokkan hewan coba mencit yang diinduksi sukrosa menjadi 5 kelompok jenis perlakuan yang terdiri dari kelompok 1 untuk perlakuan Na-CMC 1% sebagai kontrol negatif, kelompok 2 dengan pemberian suspensi Acarbose sebagai kontrol positif, kelompok 3, 4, dan 5 dengan pemberian ekstrak daun jagung manis (Zea mays saccharata) dengan dosis berbeda yaitu 100 mg/KgBB, 300 mg/KgBB, 500 mg/KgBB. Hasil penelitian: penelitian yang telah dilakukan menunjukkan bahwa ekstrak daun jagung dapat menghambat kenaikan kadar glukosa pada mencit yang diinduksi sukrosa. Kesimpulan: ekstrak daun jagung memiliki aktivitas sebagai antihipeglikemia

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