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Mawaddah Ar Rachmah
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neurona.perdossi@gmail.com
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+6282130377088
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SEKRETARIAT PP PERDOSSI Apartemen Menteng Square, Tower A Blok R-19 Jl. Matraman nomor 30E, RT.5/RW.6, Kenari, Kec. Senen, Kota Jakarta Pusat, Daerah Khusus Ibukota Jakarta 10430
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Kota adm. jakarta pusat,
Dki jakarta
INDONESIA
Neurona
ISSN : 02166402     EISSN : 25023748     DOI : https://doi.org/10.52386/neurona
Core Subject : Health, Science,
Neurona merupakan satu-satunya jurnal yang memuat perkembangan penelitian dan kasus terbaru bidang neurosains oleh Perhimpunan Dokter Spesialis Saraf (PERDOSSI) Pusat di Indonesia. Jurnal ini diterbitkan bulan Maret, Juni, September dan Desember. Bidang studi cakupan NEURONA meliputi: Stroke dan Pembuluh darah Neurotrauma Neuroonkologi Neuro Infeksi Neuro Behavior Neurorestorasi Neuropediatri Gangguan Tidur Nyeri Kepala Neurootologi Neuro Intervensi Neuro Intensif Neurogeriatri Gangguan Gerak Epilepsi Neuro Epidemiologi
Articles 299 Documents
Hubungan Gangguan Penglihatan dan Faktor Lain Dengan Fungsi Kognitif Pada Lansia di Indonesia Thiantoro, Benedicta Ann Clarabelle; Turana, Yuda; Handajani, Yvonne Suzy
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 39 No 4 (2023): Vol 39 No 4 (2023)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v39i4.370

Abstract

Introduction: Vision impairment is one of the most common problems experienced by the elderly.Vision impairment may disturb an elderly’s well-being. Various studies have found significant correlationbetween hearing loss and cognitive function. Data is now available from the Indonesian Family Life Survey(IFLS). However, there is limited research in the association between vision impairment and cognitive functionand no studies have used IFLS-5 data on this topic.Aim: To evaluate the association between vision impairment and other factors with cognitive dysfunctionin Indonesia’s geriatric population.Methods: This study is a descriptive analytic study utilizing data from 2375 seniors of 60 years old andover from the fifth wave of Indonesian Family Life Survey (IFLS-5). Analysis is done through univariate, bivariate,and multivariate analysis.Results: The majority of respondents are male (82,7%), married (76,5%), living in urban areas (52,3%),and has <9 years of education (57,1%). 9,4% respondents experienced vision impairment, 13,4% experiencedADL impairment, 34,3% experienced IADL impairment, and 49,3% experienced cognitive impairment. Inbivariate analysis, marital status (p=0,004), residence (p<0,001), education (p<0,001), IADL (p<0,001), andvision impairment (p=0,049) are significantly correlated with cognitive function. In subanalysis, the use ofreading glasses in elderly with vision impairment is significantly correlated with cognitive function. Inmultivariate analysis, residence (p=0,002), education (p<0,001) and IADL (p=0,023) are significantly correlatedwith cognitive function.Discussion: Residence, education, and IADL is significantly associated with cognitive function. Visionimpairment is not significantly associated with cognitive function.Keywords: Cognitive Function, Geriatric, IFLS-5, Vision Impairment
Faktor-Faktor yang Memengaruhi Kejadian Depresi pada Lansia Berpendidikan Rendah Berdasarkan Indonesian Family Life Survey 5 Tanuwijaya, Melyana; Suryakusuma, Linda; Turana, Yuda; Handajani, Yvonne Suzy
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 40 No 1 (2023): Vol 40 No 1 (2023)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v40i1.371

Abstract

Introduction: The prevalence of depression increases with age and a high level of education is a protective factor from depression among elderly. However, majority of elderly in Indonesia are low educated which have an increased risk of depression. Aim: To determine the factors influencing the incidence of depression in low educational attainment elderly. Method: A cross-sectional study using secondary data from the 2014-2015 Indonesian Family Life Survey 5 (IFLS-5) which was conducted on respondents aged 60 years or older with low educational attainment. Depression was assessed using the Center for Epidemiologic Studies Depression Scale-10 (CESD-10), cognitive function was assessed using the Telephone Interview for Cognitive Status (TICS), the intensity of physical activity using the International Physical Activity Questionnaire (IPAQ) short-form, functional disability was assessed using 6 items of Katz Activity Daily Living (ADL) and the Lawton Instrumental Activity of Daily Living (IADL), and other variables using questions in the IFLS questionnaire. Result: Among 3481 respondents in this study, mostly aged 60-74 years (86,4%), women (55,3%), married (63,3%), working (54,9%), doing moderate-high intensity physical activity (64,6%), independent in performing ADL (87,3%), and normal in IADL (73,5%). Addition, most of them did not experience decrease in cognitive function (79,9%), had no history of hypertension (74,1%), diabetes mellitus (95%), arthritis/rheumatism (87,2%), and physical disability (99,2%), also not depressed (83,8%). Based on bivariate analysis, there was a significant relationship between age (p=0,042; RO=0,737), hypertension (p=0,005; RO=1,332), arthritis/rheumatism (p=0,000; RO=1,681), physical disability (p=0,001; RO=3,716), ADL (p=0,000; RO=1,632), and IADL (p=0,000; RO=1,907) with depression in low educational attainment elderly. However, there was no significant relationship between gender (p= 0,091), marital status (p=0,227), occupation (p=0,328), cognitive function (p=0,304), diabetes mellitus (p=0,704), and physical activity (p=0,525) with depression in low educational attainment elderly. In the multivariate analysis it was found that IADL to be the most contributing factor to the incidence of depression among low educated elderly based on IFLS-5 (p=0,000; RO=1,896). Discussion: There was a significant relationship between age, hypertension, arthritis/rheumatism, physical disability, ADL, and IADL with the incidence of depression in low educational attainment elderly with IADL being the most significant factor. Respondents with dependency (IADL) were 1,8 times, respectively, at greater risk of experiencing depression.
Efektivitas Melodic Intonation Therapy pada Afasia Tidak Lancar: Studi Meta-Analisis Sadiah, Hikmatun; Taruna, Rexsy
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 39 No 3 (2022): Vol 39 No 3 (2022)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v39i3.379

Abstract

Introduction: Melodic intonation therapy (MIT) is one of the intervention strategies to improve verbal skills in non-fluent aphasia patients.Aim: To synthesize the effectiveness of MIT on naming skills and speech repetition in individuals with post-stroke non-fluent aphasia.Methods: This research has a systematic review and meta-analysis design. Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) flow diagrams were used in this study, with three associated databases (Pubmed, Gale OneFile, and CENTRAL). Four experimental articles with a randomized controlled trial (RCT) designs were included in this meta-analysis.Results: Based on the results of data synthesis, it is known that MIT significantly affects speech repetition ability (Standardized Mean Difference (SMD)=0.75; p<0.0002; 95% CI 0.36–1.15) when compared to naming ability (SMD=0.34; 95% CI -0.10–0.78).Discussion: Giving MIT for eight weeks (5 times per week, 30 minutes per day) has the most significant effect size on speech repetition ability.
Penurunan Kesadaran dan Kejang Berhubungan dengan Peningkatan Mortalitas pada Pasien Covid-19: Studi Retrospektif di Rumah Sakit Umum Dr. Sardjito Yogyakarta Satiti, Sekar; Edyanto, Abdullah Syafiq; Pambudi Sejahtera, Desin; Nalendra Tama, Whisnu; Yuli Firlando, Afdhal; Vidyanti, Amelia Nur
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 39 No 4 (2023): Vol 39 No 4 (2023)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v39i4.381

Abstract

Introduction: Coronavirus infection has been associated with neurologic manifestations. Aim: The aim of this study was to investigate the predictors of mortality based on neurological manifestations among hospitalized COVID-19 patients. Methods: This was a retrospective study on COVID-19 patients hospitalized at Dr. Sardjito General Hospital Yogyakarta, Indonesia from March 9, 2020 to January 28, 2021. Demographic characteristics, medical history, symptoms, and clinical signs were extracted from medical records. Factors associated with the mortality were analysed using multivariate logistic regression analysis. Results: A total of 421 medical records were examined. Among them, 114 individuals died during hospitalization (27.08%). Several baseline characteristics were associated with mortality including age (OR: 1.05, 95%CI: 1.03-1.07, p = 0.000), history of diabetes mellitus (DM) (OR: 3.1, 95%CI: 1.95-4.95, p= 0.000), history of hypertension (OR: 1.88, 95%CI: 1.22-2.92, p= 0.004), and history of renal insufficiency (OR: 3.73, 95%CI: 2.2-6.32, p= 0.000). Neurological manifestation that associated with mortality were loss of consciousness (OR= 34.70, 95%CI: 12.67-95.05, p= 0.000), delirium (OR= 21.01, 95%CI: 3.85-114.51, p= 0.000), and seizure (OR= 31.01, 95%CI: 3.82-251.69, p= 0.001). On the multivariate analysis, loss of consciousness (OR: 33.10, 95%CI: 12.00-91.33, p= 0.000), and seizure (OR: 22.75, 95%CI: 2.16 to 239.81, p= 0.009) were independent predictive factors for mortality. Discussion: Loss of consciousness and seizure were neurological manifestations served as independent predictive factors for mortality in COVID-19 patients. Keywords: COVID-19, loss of consciousness, mortality, neurological manifestations, seizure
Gangguan Serebellar pada Pasien Berusia 55 Tahun dengan Multiple System Atrophy Maulidia, Agnes Annurul
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 39 No 4 (2023): Vol 39 No 4 (2023)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v39i4.388

Abstract

Multiple system atrophy is a progressive neurodegenerative disease clinically characterized by autonomic failure (urogenital, cardiovascular or both), ataxia and parkinsonism in any combination (Sidoroff). MSA is classified into Parkinsonism (MSA-P) and Cerebellar (MSA-C) sub-types. Determining the correct diagnosis for multiple system atrophy remains a challenge in daily clinical practice as a comprehensive examination is required. Few journals discuss the diagnosis and management of multiple system atrophy thoroughly. Case: A 55-year-old man came to the neurology clinic with complaints of frequent falls accompanied by typical cerebellar symptoms. Neurologic examination revealed impaired cerebellar function. MRI examination of the head with contrast showed a typical picture of cerebellar type multiple system atrophy. Conclusion: Rapid diagnosis and adequate multidisciplinary treatment are needed to prevent aggravation of multiple system atrophy symptoms. Symptomatic and supportive therapy is needed to improve the patient's quality of life.
Biomekanika Cedera Otak Traumatik pada Kecelakaan Mobil Tunggal yang Melibatkan Empat Orang Penumpang Prawiroharjo, Pukovisa; Karmila, Hanna; Mayza, Adre; Martono, Yesenia
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 39 No 3 (2022): Vol 39 No 3 (2022)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v39i3.398

Abstract

Traumatic Brain Injury (TBI) caused by traffic accidents remains the leading cause of death and disability. Based on data from the Global status report on road safety 2018, deaths caused by traffic accidents occur at a ratio of 18 per 100,000 populations. In traffic accidents, doctors are often asked to perform a verbal autopsy. When performing a verbal autopsy, knowledge of the mechanism of the accident is required to make it easier to analyse the pathomechanism and its implications for the patient. We present a case of an accident involving four passengers, which we reviewed related to the biomechanical process and implications for these four patients. The injuries that occur are influenced by various things such as the seating position in the vehicle, the mechanism of the collision, the vehicle's speed at the time of the collision and various other things, so the four have different injuries. Understanding the biomechanics of injuries in traffic accidents will help medical personnel to unravel the mechanism and sort out the possible causes of injuries
Hubungan Rasio Trigliserida-High Density Lipoprotein pada Luaran Stroke Iskemik di RSUP Prof. Dr. R. D. Kandou Manado Pambudi, Denny; Tumboimbela, Melke; Tangkudung, Gilbert
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 39 No 4 (2023): Vol 39 No 4 (2023)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v39i4.406

Abstract

ABSTRACT Introduction: Stroke is one of the causes of mortality and long-term disability in the world. Triglyceride ratio-high-density lipoprotein is an objective parameter that has been validated as a prognostic tool for outcome 3 months after ischemic stroke. Aim: To determine the relationship between triglyceride- high-density lipoprotein with ischemic stroke outcome. Methods: This study was a retrospective observational cross-sectional study in acute ischemic stroke patients treated at Prof dr. R. D Kandou Manado hospital taken by consecutive sampling. The bivariate test was analyzed using a simple linear regression method. Results: 150 acute ischemic stroke patients were included in this study, with an average age of 60.00±10.10 years, compromising 57.3% men, and average TG/HDL ratio of 3.51. Barthel's outcomes with mild dependence were 62%, while the good mRS outcomes were 52.67%. Linear regression test of the TG/HDL ratio on the Barthel scale, obtained the value of r=0.19 and the value of R square=0.038, with a value of p=0.018, and the regression line equation of the Barthel value=65.31+(-1.27) TG/HDL ratio. Whereas to the mRS scale, the value of r=0.18 and the value of R square=0.032, with a value of p=0.028, and the regression line equation of the mRS value=3.058+0.60 TG/HDL ratio. Discussion: : TG/HDL ratio has a negative relationship on the Barthel scale and a positive relationship on the mRS scale, with a weak correlation value. TG/HDL ratio is considered as an independent parameter that predict ischemic stroke outcome. Keywords: Triglycerides, high-density lipoprotein , Ischemic Stroke, Outcome
Keluaran Klinis Pasien Stroke dengan Covid-19 di RSUD Dr. Soedomo Trenggalek pada Tahun 2020 - 2021 Abdillah, Mi'rajatul; Sholehuddin, Muhammad Afif; Ikhromi, Noryanto; Subroto, Antonius Gatot
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 39 No 4 (2023): Vol 39 No 4 (2023)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v39i4.408

Abstract

Introduction: In Indonesia, there is still little data on stroke with COVID-19 patients. COVID-19 patients also experience stroke. This study aims to determine the clinical outcomes of stroke with COVID-19 patients in Trenggalek, Indonesia. Methods: This study used a cross-sectional study design by comparing the clinical outcomes of stroke patients with COVID-19 and stroke patients without COVID-19 at RSUD Trenggalek. The independent variable studied in this study was COVID-19 infection status based on medical records. The study group was subjects with stroke and COVID-19 infection. The control group is subjects with stoke without COVID-19 infection. The dependent variables studied in this study were length of hospitalization, cost of care, and mortality rate. Results: This study found that the average age of patients stroke with COVID-19 was 65 years. Stroke patients with COVID-19 have a higher mortality rate than stroke patients without COVID-19 (p<0.001; 95% CI). The average cost of care in the group of stroke patients with COVID-19 was significantly higher than the stroke group without COVID-19 (p<0.001; CI 95%). However, there was no statistically significant difference in the length of treatment between the control group and the intervention group. (p=0,326). Conclusion: Stroke patients with COVID-19 have higher mortality rates and treatment costs than those without COVID-19. Old age has a higher risk of being infected with the COVID-19 type. However, no significant difference was found in the length of treatment.
Pengaruh Relaksasi Benson terhadap Kualitas Tidur Mahasiswa Fakultas Kedokteran Universitas Diponegoro Roselina, Jessica; Kesoema, Tanti Ajoe; Pasmanasari, Elta Diah; Basyar, Edwin
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 39 No 3 (2022): Vol 39 No 3 (2022)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v39i3.409

Abstract

Introduction: Sleep is the basic need that should be fulfilled to help the body to work optimally. Sleep disorders are quite prevalent among medical students. Sleep deprived medical students experience decreased cognitive function, mood, alertness, and fatigue. Benson relaxation is a non-pharmacological therapy that can improve sleep quality in elderly. Limited study was published on the effect of Benson relaxation on young adults’ sleep quality. Aim: To analyze the effect of Benson relaxation on sleep quality in students of Faculty of Medicine Diponegoro University. Methods: A non-invasive quasi experimental study with one group pre and post-test design was conducted. Which involved 29 medical students from class of 2018-2021. Purposive sampling technique was performed. Benson relaxation was done for 14 consecutive days, 15 minutes every day. The subject’s sleep quality was assessed by the PSQI questionnaire before and after Benson relaxation treatment. Data was analyzed using IBM SPSS Statistics 22.0 and the test used was paired T-test. Results: The pre-test score mean was 9,38 ± 1,821 meanwhile the post-test score mean was 4,31 ± 2,106. There was statistically significant change in sleep quality before and after Benson relaxation (p = 0,004). Discussion: Benson relaxation increased sleep quality in students of Faculty of Medicine Diponegoro University. Keywords: Sleep quality, medical students, Benson relaxation
Korteks Prefrontal pada Kelompok Remaja Adiksi Pornografi Lebih Kecil dibandingkan Remaja Tanpa Adiksi Pornografi Prawiroharjo, Pukovisa; Edmi Edison, Rizki; Ellydar, Hainah; Pratama, Peter; Evangeline Imelda Suaidy, Sitti; Amani, Nya'Zata; Carissima, Diavitri; Faradisa Hatta, Ghina
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 39 No 4 (2023): Vol 39 No 4 (2023)
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Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background and aims: Increasing popularity of Internet has exposed our children pornography addiction. As in other types of addiction, it affects a brain region known as prefrontal cortex (PFC), which is important in executive functions and inhibitory control. However, this region was loosely defined, and there was no consensus for that definition. We aimed to use volumetric MRI in finding the defining region of PFC which would be suitable in distinguishing pornography addicted juveniles. Methods: We enrolled 30 juveniles (12-16 y.o.) consisting of 15 pornography addiction and 15 non-addiction subjects. We proposed several models of PFC definition from mix-and-matched subregions, consisting of orbitofrontal (OFC), inferior frontal gyrus (IFG; pars orbitalis, opercularis, and triangularis), dorsolateral PFC (DLPFC), and anterior cingulate (ACC). Suitable PFC definition was defined as models which volume statistically different between both groups. Brain volumetric was measured using 3D-T1 3T MRI images and analyzed using FreeSurfer® for automatic cortical reconstruction and brain segmentation (recon-all command). Results: We found significant differences between groups in 6 models, which mainly included OFC, ACC, and DLPFC, with models devoid of DLPFC had lowest mean differences. Conclusion: The most suitable definition of PFC for pornography addiction study should consist of OFC, ACC, and especially DLPFC. Inferior frontal gyrus pars orbitalis was not necessary for this purpose, but may increase effect size if it is included.