cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Nanang Yunarto
Contact Email
jurnalkefarmasian@gmail.com
Phone
+628156867400
Journal Mail Official
jurnalkefarmasian@gmail.com
Editorial Address
Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan Kementerian Kesehatan RI Jl. Percetakan Negara No. 23 - Jakarta 10560
Location
Kota adm. jakarta pusat,
Dki jakarta
INDONESIA
Jurnal Kefarmasian Indonesia
Published by Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan
ISSN : 2085675X     EISSN : 23548770     DOI : -
Core Subject : Health, Science,
Chemistry Medicine & Pharmacology
Pharmaceutical Technology, Pharmacology, Pharmaceutical Chemistry, Traditional Medicines, and Pharmaceutical Care.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 269 Documents
 7   8   9   10   11 
Kebijakan Pengawasan Iklan Pangan Olahan di Indonesia Susyanty, Andi Leny; Supardi, Sudibyo; Handayani, Rini Sasanti; J.Herman, Max; -, Raharni
Jurnal Kefarmasian Indonesia VOLUME 4. NOMOR 1 FEBRUARI 2014
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v4i1.2897

Abstract

The Act of The Republic of Indonesia Number 7 of 1996 on Food mentioned that every label and or advertisement concerning food to be sold must mention information concerning the food correctly and not misleading. The government shall regulate, supervise and the measure which are needed, in order that an advertisement concerning food which is sold does not contain information which may be misleading. This cross-sectional study was conducted to Identify legislation related to food advertisement. Primary data collection by means of indepth interviews and Round Table Discussion (RTD), as well as secondary data collection concerning institusional report and monitoring documentation has been used. The data were analysed qualitatively. The findings indicate that monitoring of food advertisement only at the provincial level. Monitoring of Processed foodstuff advertisement by testimony in broadcast media, inset in the event program at television and advertising on the Internet is not optimal and it’s required cross-sectoral coordination.
Aktivitas Antidermatofitik Ekstrak Daun Urang-aring (Eclipta alba (L.) Hassk) terhadap Trichophyton mentagrophytes Ikawati, Hartanti Dian
Jurnal Kefarmasian Indonesia VOLUME 4. NOMOR 1 FEBRUARI 2014
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v4i1.2898

Abstract

Emergence of drug resistance in a fungal infection therapy had driven the need for a search of a new therapeutic agent. Traditional approach is now being marked by most people to combat this resistance problem. Plants can acts as a source of antimicrobial agents. Eclipta alba,L. Hassk leaves has been traditionally used to cure skin illnesses caused by fungal infection. The aim of this study is to analyze the antidermatophytic activity of Eclipta alba, L. Hassk leaves extract against Trichophyton mentagrophytes. Eclipta alba (L.) Hassk leaves were extracted gradually with hexane, ethyl acetate, ethanol and water. A serial concentration 0 mg/ml, 12,5 mg/ml, 25 mg/ml, 50 mg/ml and 100 mg/ml of those four fraction was made subsequently. The antidermatophytic activity was done by gel diffusion method. Zone of inhibition was measured and analyzed with ANOVA continued with DMRT (Duncan Multiple Range Test). The antifungal test showed that hexane, ethyl acetate and ethanolic extract of Eclipta alba, L. Hassk leaves were effective to inhibit the growth of Trichophyton mentagrophytes but not significantly different (p≥0,05). Water extract showed no inhibition on Trichophyton mentagrophytes
Butylated hydroxyanisole sebagai Bahan Aditif Antioksidan pada Makanan dilihat dari Perspektif Kesehatan Fitri, Nyoman
Jurnal Kefarmasian Indonesia VOLUME 4. NOMOR 1 FEBRUARI 2014
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v4i1.2899

Abstract

Butylated hydroxyanisole (BHA) is widely used since 1947 as antioxidant food additives used to prevent oils, fats and shortenings from oxidative deterioration and rancidity. It has been extensively studied for potential activities and its toxicities. This review summarized experimental studies that had been carried out on animals and humans as well. We also briefly reviewed about its absorptions, metabolisms, excretions and carcinogenicity from health perspective. At present there is sufficient evidence for carcinogenicity of BHA, but there is hardly any indication that BHA is genotoxic. Keywords: Butylated hydroxyanisole, Additive, Ef
Toksisitas Akut dan Subkronis Ramuan Ekstrak Kelor dan Klabet sebagai Pelancar ASI dan Penambah Gizi Widowati, Lucie; Winarno, M Wien; Intan, Putri Reno
Jurnal Kefarmasian Indonesia VOLUME 4, NOMOR 2, AGUSTUS 2014
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Insufficient breast milk intake from a mother to their babies may cause a poor infant growth. We have conducted a research on mixture of klabet seed extracts (Trigonella foenum-graecum L.) and kelor leaf extract (Moringa oleifera Lamk.) (1:1) for increasing breast milk production in nursing mothers and nutritional supplement for infants. The study is a completely randomized design. We used white rats (Rattus novergicus), Wistar strain, as many as 50, that were divided into 5 dose groups for the acute toxicity testing and 40 rats in 4 dose groups for the sub-chronic toxicity testing.The acute toxicity testing of fenugreek seed extracts and moringa leaf extracts (1:1) results in a pseudo value LD50 >4,000 mg/200g bw, therefore we classified the materials to practically non-toxic (PNT). For the subchronic toxicity testing, the result showed a normal state on liver and kidney function.
Isolasi dan Identifikasi Struktur Karotenoid dari Ekstrak Bayam Merah (Amaranthus Tricolor L.) Sulistyaningrum, Novi
Jurnal Kefarmasian Indonesia VOLUME 4, NOMOR 2, AGUSTUS 2014
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Amaranthus tricolor L. was reported as source of carotenoid compounds (tetraterpenoids) which is a natural pigments and has bioactivity as antioxidants. They are beneficial to health. Carotenoids isolate are obtained by maceration method in methanol, saponification with KOH / MeOH 5%, fractionated by vacuum column chromatography, preparative thin layer chromatography (preparative-TLC) repeatedly and each fraction monitored using thin layer chromatography (TLC). Structure analysis of carotenoids based on UV, IR and GCMS spectroscopic data showed similarities as lutein structure.
Pengaruh Pemberian Fraksi Protein Ekstrak Kuda Laut (Hippocampus kuda Bleeker, 1852) terhadap Peningkatan Kadar Hemoglobin Mencit (Mus musculus L) Adam, Kindi; Fitria, Laksmindra; Sarto, Mulyati
Jurnal Kefarmasian Indonesia VOLUME 4, NOMOR 2, AGUSTUS 2014
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Seahorse (Hippocampus kuda) is known to have a high concentration of iron, taurin and progesteron as testosteron precursor. Seahorse extract can increase the production of testosterone hormone of mice. On the erythrocytes development, kidney is stimulated to release erythropoietin hormone in case of hypoxia and also related with testosterone production. Erythropoietin control erythrocytes development and increase hemoglobin synthesis. The objective of experiment was to study the effect of seahorse extract as supplemented food in optimal concentration in range of 100, 200 and 300 mg/kg body weight on mice’s hematopoiesis and erythropoiesis. Each of treatment groups consist of 5 mices. The observed parameters were hematocrit value, hemoglobin concentration and renal index which observed on day 0, 34 and 67. The result showed that treatment of seahorse protein fraction extract until 300 mg/kg body weight dosage have no effect to the hematocrit value. The 200 mg/kg body weight extract dosage was able to increase the hemoglobin rate measurement. Renal index of Mice on day 34 and 67 after treatment did not give significant difference among treatment and control
Perbandingan Penggunaan Obat Rasional Berdasarkan Indikator WHO di Puskesmas Kecamatan antara Kota Depok dan Jakarta Selatan Kardela, Widya; Andrajati, Retnosari; Supardi, Sudibyo
Jurnal Kefarmasian Indonesia VOLUME 4, NOMOR 2, AGUSTUS 2014
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Procurement and distribution of drugs to community health centers generally performed by health office districts, such as Depok City, but in the province of Jakarta conducted by the community health centers in sub district. The purpose of the study was to compare the rational drug use among community health centers in the district of Depok City and South Jakarta. This study used a cross-sectional design conducted in treatment and non- treatment community health centers in District X Depok City and district Y South Jakarta period MarchOctober 2011. Rational drug use data was collected in accordance with WHO procedure. Data was analyzed by Kruskal Walis test. Conclusion of the study shows that rational drug use based on prescribing indicators in community health centers in Depok City relatively better than South Jakarta, but no statistically significant (p> 0.05). Rational drug use based on patient care indicators in community health center South Jakarta is relatively better than Depok city, however, showed no statistically significant (p> 0.05). In contrast to the indicator of drug preparation time in health centers Depok relatively faster than South Jakarta, showed statistically significant (p
Optimasi Formula Tablet Salut Enterik Natrium Diklofenak dengan Bahan Penyalut Kollicoat 30 D Yunarto, Nanang
Jurnal Kefarmasian Indonesia VOLUME 4, NOMOR 2, AGUSTUS 2014
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Diclofenac sodium is an analgetic and antiinflammation drug and commonly used by oral administration. Because of it’s side effects that can cause stomach irritation, nausea and vomiting, it’s made in the form of enteric-coated. Enteric-coated formulations developed used organic solvent having toxicity and flammability risks. The aim of this study is to develop diclofenac sodium enteric-coated tablets with a water-based coating material. Coating material used is Kollicoat 30 D which is a derivative of acrylic polymer that can dispersed in water. Optimalization of the formula is done by the weight gain 4%, 6% and 8%. The result showed that enteric coated tablets used coating material with weight gain 8% gave the best result with all parameters meet the requirements of the test, there was no change in acid medium for 2 hours and stable released active ingredient in alkaline medium.
Formulation of Dihydroartemisinin-Piperaquine (DHP) Generic Tablet as Antimalarials Drug Yunarto, Nanang; Isnawati, Ani; Aini, Nurul; Kurniatri, Arifayu Addiena; Adelina, Rosa; Setyorini, Herni Asih
Jurnal Kefarmasian Indonesia VOLUME 6, NOMOR 1, FEBRUARI 2016
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v6i1.2911

Abstract

The incidence of malaria in Indonesia is about two million cases annually. Dihydroartemisinin-piperaquine (DHP) is the first line therapy recommended for uncomplicated malaria treatment, whereas DHP is still fully imported. The generic DHP tablet formulation has the potential to become the first of DHP drug which is locally produced. This study is aimed to formulate generic DHP film coated tablets for antimalaria drug. Tablets were compressed with the combination of wet granulation for piperaquine phosphate (PQP) and direct compression method for DHA and coated with a moisture barier coating material. The parameters to evaluate the quality of DHP tablets are physical properties, assay, and dissolution test. DHA and PQP assay were performed by HPLC method. The dissolution testing was conducted by in house method using HCl 0.1 N medium. The result shows physical properties of filmcoated tablets meet the requirement, i.e. uniform weight, 7.0-8.5 kp hardness, 0.02% friability and 3 minute 22 seconds disintegration. The assay to determine DHA in tablet was 95.17% and PQP was 97.05%. The result of dissolution testing shows the content of DHA and PQP in the tablet were 113.51% and 96.55%, respesctively. The formulation which is developed meets the general requirement of API in tablet 90–110% and dissolution requirement >75%.
Deteksi Resistensi Oseltamivir Influenza A (H1N1pdm09) dari Pasien Infeksi Saluran Pernafasan Akut Berat di Indonesia tahun 2014 Setiawaty, Vivi; Pawestri, Hana Apsari; Susilarini, Ni Ketut
Jurnal Kefarmasian Indonesia VOLUME 6, NOMOR 1, FEBRUARI 2016
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v6i1.2912

Abstract

Influenza viruses are classified into subtypes based on two surface antigens known as hemagglutinin (HA) and neuraminidase (NA). Antigenic changes of influenza virus can cause resistance to antiviral drugs which is already limited in variation. Resistance to the drugs used recently are due to antigenic drift by point mutation in a single amino acid at position 275 (H275Y). The purpose of this research is to identify the presence of influenza virus A (H1N1pdm09) that were resistant to oseltamivir from cases of severe acute respiratory infection (SARI)in Indonesia in 2014 by using a rapid detection test. Detection of oseltamivir resistance in NA gene is to identify the single nucleotide polimorphism (SNP) at position 275 (H275Y) using the real-time RT-PCR method from clinical specimens SARI case. A total of 870 specimens from six sentinel hospitals were collected and 15 of them positive H1N1pdm09. Of the 15 clinical specimens, H1N1pdm09 virus strains that have mutations H275Y were not found. Based on this finding, it can be concluded that during the year 2014, there is no influenza virus A (H1N1pdm09) resistant to oseltamivir from SARI cases specimen in six sentinel hospitals in Indonesia.

Page 9 of 27 | Total Record : 269

 7   8   9   10   11 

Filter by Year

2009 2025


Reset
Filter By Issues
All Issue VOLUME 15, NUMBER 2, JULY-DECEMBER 2025 VOLUME 15, NUMBER 1, FEBRUARY 2025 VOLUME 14, NUMBER 2, AUGUST 2024 VOLUME 14, NUMBER 1, FEBRUARY 2024 VOLUME 13, NUMBER 2, AUGUST 2023 VOLUME 13, NOMOR 1, FEBRUARI 2023 VOLUME 12, NOMOR 2, AGUSTUS 2022 VOLUME 12, NOMOR 1, FEBRUARI 2022 VOLUME 11, NOMOR 2, AGUSTUS 2021 VOLUME 11, NOMOR 1, FEBRUARI 2021 VOLUME 10, NOMOR 2, AGUSTUS 2020 VOLUME 10, NOMOR 1, FEBRUARI 2020 VOLUME 9, NOMOR 2, AGUSTUS 2019 VOLUME 9, NOMOR 1, FEBRUARI 2019 VOLUME 8, NOMOR 2, AGUSTUS 2018 VOLUME 8, NOMOR 1, FEBRUARI 2018 VOLUME 7, NOMOR 2, AGUSTUS 2017 VOLUME 7, NOMOR 1, FEBRUARI 2017 VOLUME 6, NOMOR 2, AGUSTUS 2016 VOLUME 6, NOMOR 1, FEBRUARI 2016 VOLUME 5, NOMOR 2, AGUSTUS 2015 VOLUME 5, NOMOR 1, FEBRUARI 2015 VOLUME 4, NOMOR 2, AGUSTUS 2014 VOLUME 4. NOMOR 1 FEBRUARI 2014 VOLUME 3, NOMOR 2, AGUSTUS 2013 VOLUME 3, NOMOR 1, FEBRUARI 2013 VOLUME 2 NOMOR 2, AGUSTUS 2012 VOLUME 2, NOMOR 1, FEBRUARI 2012 VOLUME 1, NOMOR 3, 2009 VOLUME 1, NOMOR 2, 2009 VOLUME 1, NOMOR 1, 2009 More Issue