cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Ahmad Shafwan S. Pulungan
Contact Email
pulungan.shafwan@gmail.com
Phone
+6281370329288
Journal Mail Official
biosains@unimed.ac.id
Editorial Address
Program Studi Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Negeri Medan Jl. Willem Iskandar Psr V Medan Estate, Sumatera Utara
Location
Kota medan,
Sumatera utara
INDONESIA
JBIO: jurnal biosains (the journal of biosciences)
Published by Universitas Negeri Medan
ISSN : 24431230     EISSN : 24606804     DOI : https://doi.org/10.24114/jbio.v6i1
Core Subject : Health, Science, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology
Jurnal Biosains (JBIO) features works of exceptional significance, originality, and relevance in all areas of biological science, from molecules to ecosystems, (ie genetic, microbiology, ecology, biosystematic, biostatistic) including works at the interface of other disciplines, such as chemistry, medicine,physic and mathematics. We also welcome data-driven meta-research articles that evaluate and aim to improve the standards of research in the life sciences and beyond. Our audience is the international scientific community as well as educators, policy makers, patient advocacy groups, and interested members of the public around the world.
Arjuna Subject : Biokimia, Genetika dan Biologi Molekuler - Biokimia, Genetika dan Biologi Molekuler (Lain-Lain)
Articles 285 Documents
 25   26   27   28   29 
Basil Leaf Extract (Ocimum americanum L.) as a Natural Anticoccidial Agent: Impacts on Body Weight and Cecal Histopathology in Chickens Rahmad H. Gultom; Martina Asiati Napitupulu; Eniwati Eniwati
JURNAL BIOSAINS Vol. 12 No. 2 (2026): JURNAL BIOSAINS
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/tz0v8w96

Abstract

This study aimed to evaluate the effectiveness of basil leaf extract (Ocimum americanum L.) on body weight and cecal histopathology in native chickens infected with Eimeria tenella. Eimeria tenella is recognized as one of the most pathogenic Eimeria species in poultry and is responsible for coccidiosis characterized by severe cecal lesions, including hemorrhage, necrosis, and inflammatory cell infiltration (Chapman, 2014; Koutny et al., 2021). Basil leaves were selected because they contain phytochemical compounds such as flavonoids, tannins, and essential oils with potential antibacterial, antioxidant, and immunomodulatory activities (Dwivedi et al., 2021; Kadhim & Abbas, 2023). The experiment employed a completely randomized design consisting of five treatment groups: a negative control, a positive control, and three basil extract treatments at concentrations of 0.05%, 0.10%, and 0.20%. Parameters observed included body weight and cecal histopathological changes. The results demonstrated that basil extract administration influenced the cecal condition of infected chickens, with the 0.10% dose producing the most favorable outcomes compared with the other doses. Histopathological examination revealed the presence of oocysts, necrosis, macrophage infiltration, inflammation, and hemorrhage in infected chickens; however, the severity of lesions varied among treatments. These findings indicate that basil leaf extract has potential as a natural supplement to support the health of native chickens
Potential Antithrombotic Candidate of Moringa oleifera L. Leaf: Study In Vitro Microscopic Evaluation of Erythrocyte Morphology Bio Putri ayanti; Nurbidayah; Nurul Amalia; Muhammad Arsyad; Maya Herliana Sasmitha; Noor Zahwa Mubarokah; Dina Novita Sari
JURNAL BIOSAINS Vol. 12 No. 2 (2026): JURNAL BIOSAINS
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/199bx227

Abstract

Moringa oleifera leaves are rich in bioactive compounds with purported therapeutic properties, including potential antithrombotic activity. This study evaluated the in vitro effects of Moringa oleifera leaf filtrate on erythrocyte morphology and aggregation. Whole blood samples were treated with varying concentrations of the filtrate (25%, 50%, 75%, and 100%), and microscopic examination was performed to assess changes in erythrocyte morphology and aggregation patterns. The results showed distinct, concentration-dependent effects on erythrocytes. At a low concentration of 25%, erythrocytes maintained normal morphology and remained evenly distributed without signs of aggregation. Conversely, increasing the concentration to 50%–100% induced significant poikilocytosis and anisocytosis, along with increased erythrocyte aggregation characterized by rouleaux formation. These findings suggest that although Moringa oleifera L. filtrate exhibits promising antithrombotic potential at low concentrations, higher concentrations may negatively alter erythrocyte integrity and promote aggregation. Further research is needed to elucidate the underlying molecular mechanisms and establish a safe therapeutic range.
In silico Evaluation of Physicochemical and ADMET Properties of Bioactive Compounds from Marchantia paleacea. Hestia Hairima; Ghea Brigitta Dotulong; Nurul Nisa Primadiaty
JURNAL BIOSAINS Vol. 12 No. 2 (2026): JURNAL BIOSAINS
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jpgmn753

Abstract

  Marchantia paleacea is a liverwort with diverse secondary metabolites of pharmacological interest. This study aimed to evaluate the physicochemical and ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) properties of eighteen bioactive compounds previously identified from M. paleacea by GC-MS analysis using an in silico approach. Physicochemical parameters were analyzed using SwissADME, ADMET predictions were performed using pKCSM and ProTox 3.0 for toxicity class analysis. Results showed that most compounds complied with Lipinski’s Rule of Five (RO5), demonstrating good oral drug-likeness. All compounds exhibited high human intestinal absorption (86-95%), favorable BBB permeability, and CNS permeability values remained low. Most compounds did not significantly interact with major CYP450 isoenzymes or P-glycoprotein. Toxicity prediction revealed that the majority of compounds were non-mutagenic (Ames-negative), non-hepatotoxic, and did not inhibit the hERG channel, suggesting a relatively safe pharmacological profile. Exceptions included 2-nitro-cyclohexanone (positive Ames test) and thymol (hepatotoxicity). Compounds such as linalool,  dodecanoic acid, n-decanoic acid, and bicyclo[2.2.2]hept5-en2-ol demonstrated particularly favorable drug-like characteristics, warranting further experimental validation. These findings provide a computational foundation for prioritizing M. paleacea bioactive compounds for future drug development.   
InnoClean Bio: Emulsion Engineering of Mangosteen and Pineapple Peel Extract as an Organic Cleaner Supporting the Circular Economy Dhea Ananda Nasution; Anna Sakila; Dwi Muliani; Siti Aisyah; Sri Muthii'ah Rizky; Sri Masnita Pardosi
JURNAL BIOSAINS Vol. 12 No. 2 (2026): JURNAL BIOSAINS
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/fhap2b28

Abstract

Pineapple peel and mangosteen peel waste have the potential to be used as raw materials for environmentally friendly organic cleaning products. This study aims to produce an eco-enzyme-based organic cleaning product through the fermentation of 150 grams of pineapple peel powder, 90 grams of mangosteen peel powder, and 1500 mL of water for 14 days. After fermentation, 2 tablespoons of vinegar and 3 mL of essential oil were added. Product characterization included pH, homogeneity, stability, and cleaning effectiveness tests. The results showed that the product's pH decreased from 5 to 4, had good homogeneity and stability, and produced little foam when used. The product is able to clean glass or mirrors, house floors, household appliances, and motor vehicles. In addition, the fermentation dregs have the potential to be used as organic fertilizer. The results show that InnoClean Bio has the potential to be an effective organic cleaning alternative while supporting the implementation of the circular economy concept by using organic waste into useful products.
The Effect of White Cempaka Flower Extract (Magnolia alba) on Rabbit (Oryctolagus cuniculus) Hair Growth Sheila Wulandari; Arif Sardi; Raudhah Hayatillah
JURNAL BIOSAINS Vol. 12 No. 2 (2026): JURNAL BIOSAINS
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/bags6v21

Abstract

Penelitian ini bertujuan untuk menguji efektivitas ekstrak etanol tonik bunga cempaka putih (Magnolia alba) terhadap pertumbuhan rambut pada Kelinci (Oryctolagus cuniculus) dan menentukan konsentrasi optimalnya. Metode eksperimental berdasarkan Rancangan Acak Kelompok (RAK) digunakan dengan lima kelompok perlakuan: konrol negative (aquadest), kontrol positif (Regrou), dan tonik ekstrak bunga cempaka putih dengan konsentrasi 3%, 6%, dan 12%. Preparat tonik diuji sifat fisik dan stabilitasnya, kemudian diaplikasikan secara topical pada punggung Kelinci selama 28 hari. Pengukuran panjang rambut dilakukan setiap minggu dan dianalisis menggunakan ANOVA dua arah berulang. Hasil evaluasi fisik menunjukkan bahwa semua formula homogen, stabil, dan memenuhi standar pH kulit. Pada minggu ke-4, formula 3% menghasilkan pertumbuhan rambut rata-rata tertinggi (1,97 ± 0,49 cm), melebihi kontrol positif (1,87 ± 0,71 cm). Penigkatan konsentrasi (6% dan 12%) justru mengurangi efektivitas karena peningkatan viskositas dan potensi saturasi reseptor. Uji ANOVA menunjukkan bahwa faktor waktu memiliki pengaruh yang sangat signifikan (p < 0,001). Kesimpulannya, ekstrak bunga cempaka putih 3% adalah yang palig optimal dan berpotensi dikembangkan sebagai sediaan tonik rambut alami. This study aims to test the effectiveness of the tonic ethanol extract of white cempaka flowers (Magnolia alba) on hair growth in rabbits (Oryctolagus cuniculus) and determine the optimal concentration. An experimental method based on a Randomized Block Design (RBD) was used with five treatment groups: negative control (aquadest), positive control (Regrou), and white cempaka extract tonic with concentrations 3%, 6%, and 12%. The tonic preparation was tested for its physical properties and stability, followed by topical application on the rabbit’s back for 28 days. Hair length measurements were taken weekly and analyzed using a two-way repeated-measure ANOVA. The results of the physical evaluation show that all formulas are homogeneous, stable and meet skin pH standards. At week 4, the 3% formula produced the highest average hair growth (1,97 ± 0,49 cm), exceeding the positive control (1,87 ± 0,71 cm). Increasing the concentration (6% and 12%) actually reduces effectiveness due to increased viscosity and potential receptor saturation. The ANOVA test shows that the time factor has a very significant effect (p < 0,001). In conclusion, 3% white cempaka flower extract is most optimal and has the potential to be developed as a natural hair tonic preparation

Page 29 of 29 | Total Record : 285

 25   26   27   28   29 

Filter by Year

2013 2026


Reset
Filter By Issues
All Issue Vol. 12 No. 2 (2026): JURNAL BIOSAINS Vol. 12 No. 1 (2026): JURNAL BIOSAINS Vol. 11 No. 3 (2025): JURNAL BIOSAINS Vol. 11 No. 2 (2025): JURNAL BIOSAINS Vol. 11 No. 1 (2025): JURNAL BIOSAINS Vol. 10 No. 3 (2024): JBIO : JURNAL BIOSAINS (THE JOURNAL OF BIOSCIENCES) Vol. 10 No. 2 (2024): JBIO : JURNAL BIOSAINS (THE JOURNAL OF BIOSCIENCES) Vol 10, No 2 (2024): JBIO : JURNAL BIOSAINS (THE JOURNAL OF BIOSCIENCES) Vol. 10 No. 1 (2024): JBIO : JURNAL BIOSAINS (THE JOURNAL OF BIOSCIENCES) Vol 10, No 1 (2024): JBIO : JURNAL BIOSAINS (THE JOURNAL OF BIOSCIENCES) Vol 9, No 3 (2023): JBIO : Jurnal Biosains (The Journal of Biosciences) Vol. 9 No. 3 (2023): JBIO : Jurnal Biosains (The Journal of Biosciences) Vol 9, No 2 (2023): JBIO : Jurnal Biosains (The Journal of Biosciences) Vol 9, No 1 (2023): JBIO : Jurnal Biosains (The Journal of Biosciences) Vol 8, No 3 (2022): JBIO: jurnal biosains (the journal of biosciences) Vol 8, No 2 (2022): JBIO: jurnal biosains (the journal of biosciences) Vol 8, No 1 (2022): JBIO: jurnal biosains (the journal of biosciences) Vol 7, No 3 (2021): Jurnal Biosains Vol 7, No 2 (2021): Jurnal Biosains Vol 7, No 1 (2021): Jurnal Biosains Vol 6, No 3 (2020): Jurnal Biosains Vol 6, No 2 (2020): Jurnal Biosains Vol 6, No 1 (2020): Jurnal Biosains Vol 5, No 3 (2019): Jurnal Biosains Vol 5, No 2 (2019): Jurnal Biosains Vol 5, No 1 (2019): Jurnal Biosains Vol 4, No 3 (2018): Jurnal Biosains Vol 4, No 2 (2018): Jurnal Biosains Vol 4, No 1 (2018): Jurnal Biosains Vol 3, No 3 (2017): Jurnal Biosains Vol 3, No 2 (2017): Jurnal Biosains Vol 3, No 1 (2017): Jurnal Biosains Vol 2, No 3 (2016): Jurnal Biosains Vol 2, No 2 (2016): Jurnal Biosains Vol 2, No 1 (2016): Jurnal Biosains Vol 1, No 3 (2015): Jurnal Biosains Vol 1, No 2 (2015): Jurnal Biosains Vol 1, No 1 (2015): Jurnal Biosains Vol 1, No 2 (2013): Bio Hasil Review Fauziyah Harahap More Issue