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Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Published by SEKOLAH TINGGI ILMU KESEHATAN SAMARINDA
ISSN : 2443115X     EISSN : 24771821     DOI : https://doi.org/10.51352/jim
Core Subject : Health, Science,
Chemistry Immunology & microbiology Medicine & Pharmacology Nursing Public Health
Jurnal Ilmiah Manuntung is a journal on pharmaceutical and health sciences published by Sekolah Tinggi Ilmu Kesehatan Samarinda which includes the study of pharmaceutical sciences, medicine, synthetic organic chemistry, organic chemistry of natural materials, biochemistry, analytical chemistry, physical chemistry, biology, microbiology, tissue culture, botany and animals related to pharmaceutical products, nursing, midwifery, health analysts, nutrition and public health.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 326 Documents
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EKSTRAK KULIT BUAH NAGA MERAH (Hylocereus Polyrhizus) SEBAGAI ANTIOKSIDAN DALAM FORMULASI SEDIAAN LOTIO Yuska Novi Yanty; Vetria Ade Siska
Jurnal Ilmiah Manuntung Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v3i2.123

Abstract

Dragon fruit is a kind of cactus tree from the family Cactaceae. Red dragon fruit contains lots of vitamin C, vitamin E, vitamin B1, B2, and B3. These vitamins can increase energy, and metabolize food, and even improve skin quality. This study aims to determine whether red dragon fruit skin extract can be made into lotion preparation and to know the effect of variation of red dragon fruit skin extract on physical properties of lotio. Red dragon fruit skin was extracted by maceration, lotio was made using formulation with variation of dragon fruit skin extract which were F1 (3%), F2 (5%), F3 (7%). The lotio was making by mixing the oil phase into the water. Physical test results showed there was organoleptic change in F1, F2 and F3 after observation for 4 weeks. The average result of pH test for four weeks was meet the lotio requirements ranging from 4.5-8. F1 with an average of 6.5, F2 with an average of 7.25, F3 with an average of 7.5. The result of viscosity test is F1 0,5 poise, F2, F3 and F4 0 poise. The result of F1 7.0 cm, F2 7,1 cm and F3 7.5 cm. The irritation test results are not irritating on the use of F1, F2 and F3. The test results showed that F0 and F1 are more favorable. The result of this research was that red skin dragon fruit extract can be made into lotio formulation and there was influence of variation of extract concentration on the physical properties of lotio.
KADAR ASAM URAT PADA PASIEN TUBERKULOSIS DENGAN TERAPI OBAT ANTI TUBERKULOSIS (OAT) DI PUSKESMAS CEMPAKA MARET 2017 Nafila Nafila; Rizqia Nurul Haqiqi; Sari Wahyunita
Jurnal Ilmiah Manuntung Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v3i2.124

Abstract

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis that mostly attacks the lungs. Uric acid is the result of purine metabolism in the body. Actually, uric acid is a natural substance in the body but it becomes unnatural in the body when uric acid becomes up and beyond normal limits. The purpose of this study was to detemmine the description of uric acid levels in tuberculosis patients with anti tuberculosis drug therapy (OAT) at Puskesmas Cempaka. The population in this study was 22 patients with TB patiens who received OAT treatment. The sample of this research is 15 people with purposive sampling method. Examination was done in area of cempaka with capillary blood using rapid test method. Of the 15 patient studied with pulmonary tuberculosis who consumed OAT in Cempaka Puskesmas work area, obtained uric acid levels increased (26,67%) and normal levels uric acid (73,33%) in male gender (75%) and female gender (25%). Characteristics of age in the age group 41-50 years (25%), age 51-60 years (25%) In female gender. Should be monitored specifically for the symptoms of side effects of Anti Tuberculosis (OAT) by looking at clinical symptoms, such as nausea, vomiting, etc.
EVALUASI TINGKAT KEPATUHAN PENGGUNAAN OBAT ANTIHIPERTENSI PADA PASIEN PENYAKIT GINJAL KRONIK LANJUT USIA Fajriansyah Fajriansyah; Michrun Nisa
Jurnal Ilmiah Manuntung Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v3i2.125

Abstract

Chronic Kidney Disease (CKD) is a condition of kidney damage that occurs for 3 months or more in the form of structural or functional abnormalities of the kidney with or without decrease in Glomerular Filtration Rate which manifests as a pathological disorder. Treatment of CKD is closely related to medication adherence that determines a successful treatment, but patient treatment adherence is often low especially in regularity for drug use. This study aims to evaluate the level of adherence to the use of CKD patient drug at the General Hospital of Education Hasanuddin University. The research design is descriptive analysis with Cross Sectional. The data were collected by using questionnaires containing questions that led to patient characteristics, medication adherence, and factors affecting drug use. Measurement of adherence used is Modified Morisky Scale (MMS) which then analyzed using Case Management Adherence Guidelines (CMAG) against 45 subjects. The result of the research is the level of patient compliance based on quadrant level 1 as many as 8 patients (17,78%), quadrant level 2 as many as 8 patient (17,78%), level 3 quadrant 17 patient (37,77%), and quadrant level 4 of 12 patients (26.66%).
EFEK HIPOTENSIF DARI ACEi DAN ARB PADA PASIEN DIABETES MELLITUS DAN HIPERTENSI DI RSUD. ABDUL WAHAB SYAHRANIE SAMARINDA Rusdiati Helmidanora; Triswanto Sentat
Jurnal Ilmiah Manuntung Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v3i2.126

Abstract

More than two-thirds of patients with type 2 diabetes also experience hypertension whose development coincides with hyperglycemia, where each disease has a tendency to influence the increased risk of other diseases. Sundry new guidelines, such as the National Joint Committee 8, the American Diabetes Association recommend blood pressure targets in the diabetic population of <140/90 mmHg to reduce cardiovascular risk and prevent the progression of nephropathy. This study aims to determine whether there is a difference in achieving blood pressure target < 140/90 mmHg according to Join National Committee 8 between ACEi and ARB in patients with type 2 diabetes with hypertension. This research was conducted using a retrospective at internist clinic of Abdul Wahab Syahranie hospital, by taking secondary data from the medical record from blood pressure o 49 outpatients received a single antihypertensive either drug ACEi 29 people or ARB 34 people. This study showed that the achievement of target blood pressure by <140/90 mmHg (JNC 8 guideline) between ACEi 7 (28%) and ARB 5 (20,8%) group and it can be concluded that between ACEi and ARB drugs(P=0.5) there was no differsignificantly in achievement blood pressure target on type 2 diabetes with hypertension.
EFEKTIVITAS MINYAK ATSIRI KULIT JERUK BERGAMOT (Citrus bergamia) DALAM MASKER GEL PEEL-OFF SEBAGAI ANTI BAKTERI Staphylococcus aureus ATCC 29213 Intan Martha Cahyani; Retno Artiyani
Jurnal Ilmiah Manuntung Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v3i2.127

Abstract

Staphylococcus aureus is a bacterial strain that causes acne. Linalool and limoneneis are the ingredients of Citrus bergamia essensial oil which has antibacterial activity Staphylococcus aureus. This research aimed to examine the effective consentration of Citrus bergamiaessensial oil as antibacterial Staphylococcus aureus ATCC 29213. Citrus bergamia essensial oil is made in series a concentration of 1%, 2% and 3% for testing of antibacterial activity using the pitting diffusion method. Based on the test results of antibacterial activity gained an average diameter of inhibitory zone Citrus bergamiaessensial oil in a row 1,151 cm; 1,529 cm; 1,683 cm. The statistically test results showed significant difference in the antibacterial activity of Citrus bergamiaessensial oil in concentrations 1%, 2% and 3% to the growth of Staphylococcus aureus ATCC 29213. Citrus bergamiaessensial oil has effective concentration 3% as stapgylocuccus aureus antibacterial and made peel-off gel mask formula. Test of antibacterial activity obtained resistibility zone diameter 1,259 cm. The result of t-test indicated that the Citrus bergamiaessensial oil peel-off gel mask has significant affect on antibacterial activity of Citrus bergamiaessensial oil.
OPTIMASI POLIVINILPIROLIDON DAN CARBOPOL PADA SEDIAAN PATCH DISPERSI PADAT PIROKSIKAM Dwi Nurahmanto; Friska Wira Sabrina; Lidya Ameliana
Jurnal Ilmiah Manuntung Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v3i2.129

Abstract

Piroxicam, a non steroidal anti inflammatory drugs (NSAID), is an oxicam derivative which can be used for treatment of various rheumatic diseases, such as rheumatoid arthritis and osteoarthritis. Piroxicam patch is an affective approach evading piroxicam’s side effect such as peptic ulcer and first pass metabolism. One of the patch components is polymer that the function is to control the speed of drug release from the patch. The aims of this study were to determine the optimum formula of a combination of polyvinylpyrolidone (PVP) and Carbopol to % moisture content (MC) and the flux release in solid dispersion piroxicam patch using Simplex Lattice Design. Piroxicam was prepared in the form of a solid dispersion in PEG 4000 to increase its solubility. The design formula of solid dispersion piroxicam patch made with the ratio PVP : Carbopol, that were 1 : 0; 0.5 : 0.5; 0 : 1. The optimum formula was chosen with the ratio PVP : Carbopol, 1: 0, which gave the best result of % MC and flux release. The result of % MC was 6.91% and the result of flux release was 35.543 µg/cm2.menit1/2.
GAMBARAN PENGGUNAAN ANTIBIOTIK PADA PASIEN PEDIATRI INFEKSI SALURAN PERNAPASAN AKUT (ISPA) DI KLINIK SINT. CAROLUS BENGKULU Setya Enti Rikomah; Devi Novia; Septiana Rahma
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 4 No. 1 (2018): Jurnal Ilmiah Manuntung
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Antibiotics and infections are the most common problems faced by developing countries, including in Indonesia. Indonesia's awareness of the use of antibiotics rationally declines. Acute respiratory infections ranks first in terms of infant and under five mortality in developing and developing countries. This research was conducted to see the description of the use of antibiotics in patients with ISPA in Clinic Sint Carolus Bengkulu from January to December 2014. Data analysis was done by descriptive analysis with a retrospective method. The sample calculation was done by using the Slovin formula obtained by 100 samples. Of the 100 samples of this study, 57% of men and 43% of women, the age classification of acute respiratory infection was 0% of neonatal patients, 25% of infants, 32% of infants, 20% of children under five, and 23% of children, most antibiotics commonly used with ISPA is cefadroxil 60% amoxicillin 36% and erythromycin 3%, combination of TMP (trimethoprim) and SMZ (sulfamethoxazole) 1%. The type of ISPA that attacks is ISPA non pneumonia in the form of cough and cold based on medical record data at the Sint Carolus Clinic and the patient obtains the drug with a dose in safe range.
POTENSI EKSTRAK DAUN TANAMAN KARAMUNTING (Melastoma malabathricum L.) DI DAERAH KALIMANTAN SEBAGAI ANTIBAKTERI Staphylococcus aureus Rakhmadhan Niah; Riki Nirwan Baharsyah
Jurnal Ilmiah Manuntung Vol 4 No 1 (2018): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v4i1.138

Abstract

The year 2008 recorded the death toll reached 16,769 soul due to infection. Infection is one of the diseases caused by bacteria or parasites. Staphylococcus aureus is one of the bacteria causes infection of the skin that is often the case in Indonesia. Staphylococcus aureus bacterial infection can be treated naturally, one of the plants that can be utilized is plant karamunting. Plant leaf karamunting (Melastoma malabathricum l.) contain flavonoids and alkaloids that have activity as antibacterial. The purpose of this research is to know the power of drag karamunting folium of extract against the growth of Staphylococcus aureus. In vitro studies were conducted with diffusion agar method. The extraction of leaf maceration method done with karamunting solvent ethanol 96%. Concentration of karamunting folium of extract used are: 25%, 50%, 75%, and 100%. Microbiology research results indicate that karamunting folium of extract have drag against the growth of bacteria Staphylococcus aureus with extract concentration 50% yield of 5.34 mm; the concentration of extract 75% of 9.40 mm; the concentration of extract 100% of 12.43 mm.
Uji Validitas Dan Reliabilitas Kuesioner EQ-5D Bahasa Indonesia Untuk Pasien Hemodialisa Gagal Ginjal Kronik Yugo Susanto; Riza Alfian; Zainur Rahim; Karani Karani
Jurnal Ilmiah Manuntung Vol 4 No 1 (2018): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v4i1.139

Abstract

Chronic renal failure is a decrease in irreversible progressive renal function when the kidneys are unable to maintain a metabolic equilibrium. Chronic renal failure may impair the quality of life of patients it is necessary to measure the quality of life of patients with chronic renal failure. Measuring the quality of life of patients with chronic renal failure require a measuring instrument. One measure used is the instrument EQ-5D. This study aimed to find out the results of the validity and reliability of the instrument EQ-5D in patients with chronic renal failure. This study is an observational study conducted prospectively. Data were collected by questionnaire EQ-5D by all patients with chronic renal failure. The subjects were patients with chronic renal failure undergoing outpatient treatment at Hospital Ulin Banjarmasin period May - June 2017. Instrument EQ-5D in the analysis of the test reliability and validity test using test content validity. Subjects in this study amounted to 69 patients with chronic renal failure. This instrument is declared invalid as a result of content validity tested indicates the value of pearson correlation >0,23. While declared reliable because the Cronbach alpha values > 0,60. Questionnaire EQ-5D version of Indonesia has a valid and reliable so that it can be used to measure the quality of life of chronic renal failure hemodialysis patients.
FORMULASI DAN UJI EFEKTIVITAS MASKER PEEL OFF PATI JAGUNG (Zea mays sacchrata) SEBAGAI PERAWATAN KULIT WAJAH Karmilah Karmilah; Nirwati Rusli
Jurnal Ilmiah Manuntung Vol 4 No 1 (2018): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v4i1.140

Abstract

Corn is one ingredient that has been used empirically as a facial skin care. Peel-off facial mask has the advantage over the other types, it can lifted or removed as an elastic membrane easily. The purpose of this research was to formulate a peel-off facial mask of corn starch that qualifed for the evaluation of the preparation and its effectiveness test as skin care. This research is experimental research, that is making 3 formula with variation of corn starch concentration as active substance that is 5%, 10%, and 15% which aim to know optimal concentration as peel-off mask facial skin care. Based on the results of evaluation of formula A preparations with 5% active ingredient that meets the dosage evaluation, the formula that meets the evaluation of the dosage is then tested effectiveness as facial skin care. Effectiveness test using 3 respondents that is acne skin, blackhead skin, and oily skin. Test result conducted for 4 days with a view before and after use, peel-off corn starch mask capable of providing facial skin care effect is characterized by changes in skin becomes brighter, less acne and blackheads. Keywords : Peel-off facial mask, corn starch, facial skin care

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