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Jurnal Farmasi Ikifa
Published by Sekolah Tinggi Ilmu Kesehatan IKIFA
ISSN : 2808702X     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology Public Health
Jurnal Farmasi IKIFA adalah forum untuk publikasi karya berkualitas dan orisinal yang membuka diskusi dalam bidang farmasi atau sub-disiplin ilmu lainnya.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 119 Documents
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Optimasi Polimer PVP K-30 dan HPMC Dalam Sediaan Transdermal Patch Ekstrak Daun Kumis Kucing (Orthosiphon aristatus) Dengan Metode Simplex Lattice Design Dicky Setiawan; Iwan Setiawan
Jurnal Farmasi IKIFA Vol. 3 No. 2 (2024): JURNAL FARMASI IKIFA VOL.3 NO.2 JULI TAHUN 2024
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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Abstract

Optimalisasi Polimer PVP K-30 dan HPMC dalam Sediaan Patch Transdermal Ekstrak Daun Kumis Kucing (Orthosiphon aristatus) Menggunakan Metode Simpleks Desain Kisi
Perbandingan Ekstrak Empat Bahan Alam Terhadap Pertumbuhan Bakteri Staphylococcus Aureus Fathimatus Safra; Aliyah Zahra; Mutiara Ratna Riris; Rahmalia Putri Khayla; Yonathan Tri Atmodjo Reubun
Jurnal Farmasi IKIFA Vol. 4 No. 1 (2025): JURNAL FARMASI IKIFA VOL.4 NO.1 APRIL TAHUN 2025
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Staphylococcus aureus is part of the normal flora of the human body and can be found in the oral cavity (both in individuals who use orthodontic equipment), skin, respiratory tract, and digestive tract, as well as in the air and surrounding environment. The mechanism of action of antibacterial compounds includes blocking cell wall formation and affecting integrity. The ability of bacterial cell walls, inhibition of enzyme activity, and failure to combine nucleic acids and proteins are some of the antibacterial mechanisms of lime leaves extracted using essential oil, which have anti-bacterial activity with a minimum bactericidal concentration (KBM) against Staphylococcus aureus of 0.625% v/v and Escherichia coli of 1.25% v/v. Red betel leaf extract at a concentration of 60% showed an inhibitory zone for Staphylococcus aureus bacteria with an average inhibitory zone diameter of 7.96 mm against Staphylococcus aureus with a significant value (P<0.05). The anti-bacterial activity of papaya leaf ethanol extract and this phytochemical test showed that the average diameter of the inhibition zone was 8.24 mm at a concentration of 80%, followed by 8.1 mm at a concentration of 60%, 6.7 mm at a concentration of 40%, 4.96 mm at a concentration of 20%, and 3.92 mm at a concentration of 10%.
AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN DAN AKAR ALANG-ALANG (Imperata cylindrica L) TERHADAP BAKTERI Propionibacterium acnes Adesiti Aminah; Desi Sri Rejeki; Alik Kandhita Febriani
Jurnal Farmasi IKIFA Vol. 3 No. 2 (2024): JURNAL FARMASI IKIFA VOL.3 NO.2 JULI TAHUN 2024
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The reed plant (Imperata cylindrica L.) is a plant from the Poaceae family which is commonly used by the community as a herbal medicine for the leaves and roots. The benefits of the reed plant include antidiuretic, anti-inflammatory, neuroprotective and antibacterial. Reed plants have bioactive compounds of alkaloids, flavonoids, saponins and tannins that can be developed. This study aims to determine the comparison of antibacterial activity in leaf extracts with concentrations of 30, 40, 50% and alang-alang root samples with concentrations of 10, 15 and 20% against Propionibacterium acnes bacteria. This research is quantitative experimental with a maceration extraction method using 70% ethanol solvent. Testing of the antibacterial activity of the ethanol extract of Alang-alang leaves and roots against Propionibacterium acnes bacteria used the disc diffusion method. Based on the research that has been carried out, the results show that the ethanol extract of Alang-alang leaves and roots contains bioactive compounds in the form of alkaloids, flavonoids, steroids, saponins and tannins. The results of the antibacterial activity test on leaf extracts with concentrations of 30, 40 and 50 showed an inhibition zone of 7.2; 9.1 and 11.2 mm with medium, medium and strong categories. Meanwhile, in root extract samples with concentrations of 10, 15 and 20%, an inhibition zone of 8.1 was obtained; 9.2 and 11.1 mm with medium, medium and strong categories.
UJI PARAMETER SPESIFIK DAN NON SPESIFIK EKSTRAK ETANOL HERBA MENIRAN (Phyllanthus niruri Linn) Govan Hanif Sasongko; Adinda Nissa Hardianti; Dewi Cahya Roshiyana; Dian Ayu Irawan; Selvi Putrida
Jurnal Farmasi IKIFA Vol. 3 No. 2 (2024): JURNAL FARMASI IKIFA VOL.3 NO.2 JULI TAHUN 2024
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Phyllanthus niruri Linn is one of the species of the genus Phyllanus that belongs to the herb species with a height of 40–100 cm. It contains chemical compounds such as phyllanthin, hypophyllanthine, niranthin, nirurinethin, norsecurinine, phyllantenol, saponins, flavonoids, polyphenols, philanthine, hypofylanthin, potassium salts. The purpose of this study is to find out the results of specific and non-specific parameter tests as well as the metabolite content of herbal ethanol extract (Phyllanthus niruri L.). Establishing the general standard parameter of the extract is a specific parameter that includes the identity of the extracts, organoleptic extracts, and solute compounds in ethanol solvents & water, whereas non-specific parameters include the drying volume, type weight, and water content. The test results for alkaloids, saponins, tannins, polyphenols, terpenoids, extract yield, ethanol-water soluble essence content, drying loss, specific gravity, water content, total ash content, acid insoluble ash content obtained results that meet standard requirements. In the phytochemical testing of meniran extract, the secondary metabolites contained in the meniran herb were alkaloids, saponins, polyphenols, tannins. In the flavonoid test, the results did not meet the standards due to the evaporation process in the samples taking too long and several environmental factors that influenced the extraction process.
ANALISIS PERENCANAAN PENGADAAN OBAT DENGAN METODE KOMBINASI ABC-VEN DI GUDANG FARMASI PUSKESMAS X KABUPATEN BANYUASIN PERIODE 2022 Mayaranti Wilsya; Achmad Wahyudi; Sunitha Mardha Lingga; Yunilda Rosa; Khairunnisa; Sigit Cahyo Hardiansyah; Enny Octaviana
Jurnal Farmasi IKIFA Vol. 4 No. 2 (2025): JURNAL FARMASI IKIFA VOL. 4 NO. 2 JULI TAHUN 2025
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Drug procurement planning significantly impacts the quality of pharmaceutical services in Public Health Centres (PHC). Therefore, it's crucial to ensure proper planning to avoid stockpiling of unnecessary drugs and shortages of vital medications, which can ultimately decrease the quality of care. This study investigates the use of the ABC-VEN analysis method to optimize drug procurement planning within budget constraints at PHC X. Employing a descriptive, non-experimental design with retrospective data, the study analyzed drug demand data from January to December 2022. Primary data was collected through in-depth interviews with informants regarding the drug procurement planning process. The ABC-VEN analysis conducted for the period January-December 2022 categorized the drugs as follows: DAK drugs - 22 items (Priority), 87 items (Main), and 8 items (Additional); DPR drugs - 7 items (Main) and 2 items (Additional); JKN drugs - 10 items (Main) and 1 item (Additional). Based on the ABC-VEN analysis of drug procurement planning at PHC X for the January-December 2022 period, a total of 137 drug items were planned by the pharmacy warehouse. These were categorized as: 22 items in Group P (Priority), 104 items in Group U (Main), and 11 items in Group T (Additional).
FORMULASI LIP CREAM EKSTRAK KULIT JERUK KALAMANSI (Citrofortunella microcarpa L.) SEBAGAI PELEMBAP DAN SARI UMBI BIT (Beta vulgaris L.) SEBAGAI PEWARNA ALAMI Yureka Arsimida; Dwi Dominica
Jurnal Farmasi IKIFA Vol. 3 No. 2 (2024): JURNAL FARMASI IKIFA VOL.3 NO.2 JULI TAHUN 2024
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A study was conducted on creating lip cream products that include calamansi orange peel extract (Citrofortunella microcarpa L.) and beet root extract (Beta vulgaris L.) to assess their efficacy as natural dyes. The aim was to determine if calamansi orange peel extract and beetroot juice can be utilized in lip cream formulations, evaluate the impact of concentration on the physical characteristics, and assess the effectiveness of beetroot as a natural coloring agent. The study employed experimental methods, using extracts at a 4% concentration and juices at concentrations of 25%, 35%, and 45%. Organoleptic tests, pH tests, stability tests, adhesion tests, spreadability tests, and homogeneity tests were performed, and the results were analyzed every 7 days over a 28-day storage period. The findings indicated that the lip cream preparations exhibited favorable organoleptic properties and a suitable pH range of 4.6-6.9. However, they demonstrated poor stability as evidenced by changes in color on the 7th day of storage, although they had good adhesion, spreadability, and homogeneity during storage. The research confirmed that calamansi orange peel extract and beet root extract can be incorporated into lip cream formulations and can influence color characteristics. The change in color of the preparation, from its initial red color to a brownish hue on the 7th day of storage, can possibly be attributed to factors such as temperature, light, oxygen, and pH.
ANALISIS OBAT KEDALUWARSA, DEAD STOCK DAN OBAT RUSAK DI GUDANG FARMASI RUMAH SAKIT UMUM HIDAYAH PURWOKERTO Suci Wulan Sari; Desy Arisandi; Okta Mediawati
Jurnal Farmasi IKIFA Vol. 3 No. 2 (2024): JURNAL FARMASI IKIFA VOL.3 NO.2 JULI TAHUN 2024
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

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Drug procurement planning must consider the type and amount of drug needed, because it can cause excess stock and empty stock. The drug storage system in the Hospital Pharmacy Warehouse is very important in maintaining the quality of drugs. An inappropriate storage process can affect the quality of the preparation This research aimed to determine the description and analysis of expired, dead stock and damaged drugs in the Pharmacy Warehouse of Rumah Sakit Umum (RSU) Hidayah Purwokerto. This research used a qualitative descriptive method. The samples used were all expired drugs, damaged drugs and dead stock in the Pharmacy Warehouse of Rumah Sakit Umum Hidayah Purwokerto in the period January-December 2023 using the 0% indicator. In this research, 343 types of drugs were found consisting of expired drugs of 27.11% and dead stock drugs of 3.5%. This is not in accordance with the established indicators, while the percentage of damaged drugs at RSU Hidayah is 0%, this indicates that there is no stock of damaged drugs at RSU Hidayah, so it is in accordance with the established indicators. The causes of these drugs expiring and dead stock are due to a decrease in the number of patients, differences in doctor's prescribing patterns, a slightly drug stock use, so that the drugs pile up and expire.
IDENTIFIKASI SENYAWA KIMIA EKSTRAK ETANOL BIJI KEMIRI (Aleurites moluccana L) dan EKSTRAK LIDAH BUAYA (Aloe vera Burn.F) di KALIMANTAN SELATAN Sekar Satriani; Muhammad Fauzi; Hasniah
Jurnal Farmasi IKIFA Vol. 3 No. 2 (2024): JURNAL FARMASI IKIFA VOL.3 NO.2 JULI TAHUN 2024
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Mayoritas masyarakat banyak memilih menggunakan bahan alam sebagai pilihan pengobatan yang dianggap minim efek samping atau bahkan tidak memiliki efek samping. Penggunaan tanaman herbal sebagai obat-obatan tradisional telah meningkat selama 20 tahun terakhir di negara-negara berkembang. Organisasi Kesehatan Dunia atau World Health Organization (WHO) menyebutkan jika sebanyak 65% masyarakat di negara maju memakai obat-obatan tradisional. Pemakaian obat-obat tradisional di Asia terus berkembang walaupun banyak obat sintetis yang tersedia dan dipasarkan. Biji kemiri (Aleurites moluccana L) dan lidah buaya (Aloe vera) merupakan 2 dari banyaknya tanaman yang dipercaya secara turun temurun dapat mengatasi alopesia. Tujuan dari penelitian ini untuk membuktikan terdapatnya golongan senyawa kimia yang terkandung di dalam ekstrak. Metode yang digunakan adalah dengan soxhletasi biji kemiri menggunakan pelarut ethanol dan infudasi lidah buaya selanjutnya dilakukan skrining fitokimia untuk membuktikan adanya alkaloid, flavanoid, fenolik, steroid/terpenoid, tanin, dan saponin. Data dianalisa secara deskriptif kualitatif. Hasil menunjukkan ekstrak ethanol biji kemiri dan ekstrak infudasi lidah buaya mengandung alkaloid, flavanoid, fenolik, steroid/terpenoid, tanin, dan saponin.
STANDARISASI SPESIFIK, NON SPESIFIK, DAN SKRINING FITOKIMIA EKSTRAK ETANOL BUAH BELIMBING WULUH (Averrhoa bilimbi L.) Jasinca Arga Cetta Ramaniya; Adelia Nur Aini Saraswati; Anika Putri Rahmadani; Putri Lana Awallia; Shalsabila Tristananda
Jurnal Farmasi IKIFA Vol. 4 No. 1 (2025): JURNAL FARMASI IKIFA VOL.4 NO.1 APRIL TAHUN 2025
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The starfruit plant (Averrhoa bilimbi L.) has the potential to be used as traditional medicine. This plant can function as an antilithiasis, antihypercholesterolemia, and antidiabetic agent. To ensure the traditional medicinal plant provides safe, high-quality, and effective benefits, standardization is required. This practicum aims to observe the starfruit and establish the quality parameters of its ethanol extract, both specific and non-specific. The thick extract was obtained through maceration using 96% ethanol as the solvent. Organoleptic observations showed that the thick extract was dark green and had an aromatic smell. The non-specific parameters tested included moisture content using a moisture analyzer, ethanol-soluble extract content, water-soluble extract content, and total ash content. The results of the specific and non-specific parameter standardization of the starfruit extract showed that the drying loss of the simplicia weighed 2.2 grams, with a specific gravity of 0.836 grams/ml, extract moisture content of 17%, ethanol-soluble extract content of 24%, and water-soluble extract content of 56%.
UJI AKTIVITAS ANTIBAKTERI KOMBINASI BIJI PEPAYA (Carica Papaya L) DAN DAUN PANDAN WANGI (Pandanus Amaryllifolius Roxb) TERHADAP Escherichia Coli Iswandi; Siti Nur Afifah; Nurfitriyawatie
Jurnal Farmasi IKIFA Vol. 3 No. 2 (2024): JURNAL FARMASI IKIFA VOL.3 NO.2 JULI TAHUN 2024
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Carica Papaya L seeds contain various compounds such as tocopherols, terpenoids, alkaloids, carpains and flavonoids. Carica Papaya L seeds have been studied to have antibacterial activity by damaging the integrity of bacterial cell membranes. Fragrant pandan (pandanus amaryllifolius Roxb) is widely known to have benefits such as antidiabetic, anticancer, antioxidant and antibacterial. This study aims to determine the activity of a combination of Carica Papaya L seeds and pandanus amaryllifolius Roxb leaves against Escherichia coli. The method used was Kirby – Bauer diffusion with concentration an extract ratio of 1:1, 1:2 and 2:1 using a blank paper disk, and a paper disk as a positive control containing 5µl ciprofloxacin. Carica Papaya and Pandanus Amaryllifolius.Roxb extracts have antibacterial activity against Eschericia coli. Concentration 1:2 has better activity as proven to have the highest inhibition zone 7.7 mm.

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