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Klinik: Jurnal Ilmiah Kedokteran dan Kesehatan
Published by Lembaga Pengembangan Kinerja Dosen
ISSN : 2809235X     EISSN : 28092090     DOI : 10.55606
Core Subject : Health,
Medicine & Pharmacology Nursing Public Health
Klinik: Jurnal Ilmiah Kedokteran dan Kesehatan diterbitkan 3 (tiga) kali dalam satu tahun yaitu Edisi Januari, Mei, dan September. Jurnal Ilmiah Kedokteran dan Kesehatan menyajikan hasil penelitian dan tinjauan pustaka sehingga jurnal ini bermanfaat bagi dokter, pengambil kebijakan, tenaga kesehatan, dosen serta mahasiswa yang tertarik dengan publikasi ilmiah terkait Ilmu Kedokteran dan Kesehatan
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 448 Documents
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Edukasi Pemanfaatan Daun Kelor dengan Media Audio Visual terhadap Mean Arterial Preasure pada Penderita Hipertensi I'maliya, Dewi; Sukesih Sukesih; Soesanto, Edi
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 5 No. 3 (2026): September: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v5i3.6767

Abstract

Hypertension is a major public health problem that significantly contributes to morbidity and mortality due to cardiovascular diseases. Effective hypertension management requires not only pharmacological therapy but also non-pharmacological approaches supported by appropriate health education. This study aimed to analyze the effect of Moringa oleifera leaf decoction combined with audio-visual health education on the reduction of Mean Arterial Pressure (MAP) among patients with hypertension. This study employed a quasi-experimental design with a control group pre-test and post-test approach. A total of 32 respondents were selected using purposive sampling and divided into an intervention group and a control group, each consisting of 16 participants. The intervention group received health education on the utilization of Moringa oleifera leaves through audio-visual media and consumed Moringa oleifera leaf decoction for seven consecutive days, while the control group received health education without the herbal intervention. MAP measurements were conducted before and after the intervention. Data were analyzed using the Paired Sample T-Test and Independent Sample T-Test. The results showed a significant decrease in MAP in the intervention group compared to the control group, with a p-value of 0.001 (p < 0.05). These findings indicate that the administration of Moringa oleifera leaf decoction combined with audio-visual-based health education is effective in reducing Mean Arterial Pressure among patients with hypertension. This intervention may serve as a supportive non-pharmacological strategy for hypertension management in primary healthcare settings.
Hubungan antara Status Gizi dan Kualitas Tidur dengan Kelelahan Kerja pada Pekerja Operator Produksi PT PLN Nusantara Power UP Gresik Rosmita Rahma Dania; Abdul Rohim Tualeka
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 5 No. 3 (2026): September: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v5i3.6889

Abstract

Work fatigue represents a key occupational health issue that diminishes worker productivity and heightens accident risks. This study aims to examine the relationship between nutritional status, sleep quality, and work fatigue among production operators at PT PLN Nusantara Power UP Gresik. Employing a quantitative approach with an observational analytic design via cross-sectional method, the research included 50 production operators as the population, selected through total sampling. The dependent variable was work fatigue, while nutritional status and sleep quality served as independent variables. Work fatigue was assessed using the Industrial Fatigue Research Committee (IFRC) questionnaire, nutritional status via Body Mass Index (BMI), and sleep quality with the Pittsburgh Sleep Quality Index (PSQI). Data analysis utilized Pearson correlation test on SPSS at α = 0.05. Findings revealed a significant association between nutritional status and work fatigue (p = 0.009; r = 0.364), alongside a strong significant link between sleep quality and work fatigue (p < 0.001; r = 0.686).
Pulsed Radiofrequency Therapy in Eldeerly People with Trigeminal Neuralgia: A Case Report Sulistyo Bambang; Laksono Ristiawan Muji
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 5 No. 3 (2026): September: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v5i3.6921

Abstract

Introduction: A face nerve disorder known as trigeminal neuralgia is regarded as one of the most excruciating human ailments. Depending on the patient's medical comorbidities, trigeminal ganglion interventional techniques can lessen discomfort. The application of brief radiofrequency pulses via a needle tip that do not result in genuine thermal lesions is known as Pulsed Radiofrequency (PRF) therapy. Case: Elderly man complained of pain in the right upper and lower jaw. He was diagnosed atypical trigeminal neuralgia. The man got pulsed radiofrequency on the right trigeminal nerve with the help of C-arm, with temperature specifications of 42o C, voltage 45V, pulse width   20 ms, frequency 2 Hz, with a duration of 8 minutes.  1 week after the procedure, the VAS became 0. Oral therapy still continued. Discussion: The most prevalent cranial neuropathy is trigeminal neuralgia (TM). Traditional RF for TM is not without its problems. Research indicates that both early and late alterations in cellular activity, unaffected by temperature, take place in the cervical dorsal root ganglion (DRG) and rat dorsal horn following PRF exposure. According to meta-analysis, PRF is safer and more effective than conventional radiofrequency. By decreasing phosphorylated extracellular signal regulated kinase (a central sensitization biomarker), decreasing Ca 2+ influx, which lowers nerve cell potential activity, and decreasing mitochondrial membrane potential, which lowers cytosolic ATP levels, PRF modifies sensory ganglion nerve cells. Reduced sensitivity to pain results from a decrease in nerve ganglion cell activity. Conclusion PRF for trigeminal neuralgia can be alternative treatment with better safety and efficacy.
Kesehatan Bank dan Kebijakan Dividen: Pengaruh BOPO terhadap Dividend Payout Tatio pada Bank di BEI 2021–2024 Saphira Angelia; Tri Joko Prasetio
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 5 No. 3 (2026): September: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v5i3.6923

Abstract

This study examines the relationship between bank soundness measured using the CAMEL approach and the Dividend Payout Ratio of banking companies listed on the Indonesia Stock Exchange during the 2021–2024 period, with particular attention to managerial efficiency represented by BOPO. A quantitative approach with an associative research design is applied. Secondary data are collected from annual financial reports and dividend distribution reports. The sample is selected through purposive sampling, resulting in 20 banks with a total of 80 observations. Data analysis is performed using multiple linear regression with the assistance of SPSS, preceded by descriptive statistics and classical assumption tests. The simultaneous test indicates that CAR, NPL, BOPO, ROA, and LDR jointly influence the Dividend Payout Ratio. The partial test shows that CAR has a significant negative effect on the Dividend Payout Ratio, whereas LDR has a significant positive effect. In contrast, NPL, BOPO, and ROA do not show significant effects at the 5 percent significance level. The coefficient of determination suggests that the CAMEL variables explain only a limited portion of the variation in the Dividend Payout Ratio, indicating that other factors beyond the research model also contribute to banking dividend policy. These findings suggest that dividend policy in the banking sector during the observation period tends to respond more strongly to capital strengthening priorities and intermediation or liquidity dynamics than to credit risk, operational efficiency, or asset profitability.
Hubungan Antara Faktor Klinis dengan Perilaku Self Management pada Pasien Hemodialisis di RSD K.R.M.T Wongsonegoro Semarang Arnesya Tilameo; Merry Tiyas Anggraini; Hema Dewi Anggraheny
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 5 No. 3 (2026): September: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v5i3.6937

Abstract

Chronic Kidney Disease (CKD) is a condition characterized by an irreversible decline in kidney function, necessitating hemodialysis. Self-management is a crucial strategy in modifying the lifestyle of CKD patients undergoing hemodialysis. Several clinical factors, including disease duration, duration of hemodialysis, frequency of hemodialysis, complications, and comorbidities, influence self-management. This study aims to examine the relationship between clinical factors and self-management behavior in hemodialysis patients at RSD K.R.M.T Wongsononegoro, Semarang. This study used an analytical observational method with a cross-sectional approach. The sampling technique used was total sampling, involving 50 respondents. Data collection was conducted using a structured questionnaire and the Hemodialysis Patient Self-Care Measurement Scale. The relationship analysis was performed using the Spearman’s rank and mann-whitney test. The average duration of illness and hemodialysis among respondents was 32.92 months, with a mean self-management score of 64.02. All 50 respondents (100%) underwent hemodialysis twice a week. The majority of respondents experienced complications (n=45, 90%) and comorbidities (n=41, 82%). Spearman’s rank analysis indicated no significant relationship between disease duration and self-management (p=0.529) or between hemodialysis duration and self-management (p=0.529). The relationship between hemodialysis frequency and self-management could not be analyzed, as all patients underwent hemodialysis twice a week. Furthermore, the Mann-Whitney test showed no significant difference in self-management scores concerning complications (p=0.650) or comorbidities (p=0.960). There is no association between disease duration, duration of hemodialysis, frequency of hemodialysis, complications, and comorbidities with self-management behavior.
Hubungan Antara Konsep Diri dengan Kualitas Hidup Pasien yang Menjalani Kemoterapi di Ruang Kemoterapi RS Urip Sumoharjo Tahun 2025 Selvia Ajeng Pertiwi; Rika Damayanti; Ardinata Ardinata; Feri Agustriyani
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 5 No. 3 (2026): September: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v5i3.6939

Abstract

The number of cancer cases worldwide based on GLOBOCAN 2020, an online database from the International Agency for Research on Cancer (IARC), reached 19.3 million cases in 2020, increasing compared to 18.1 million cases in 2018. This increase reflects the growing global burden of cancer and its impact on patients’ quality of life. This study aimed to determine the relationship between self-concept and quality of life among patients undergoing chemotherapy at RS Urip Sumoharjo in 2025. This study employed a quantitative research design with a cross-sectional approach. The research was conducted in November 2025 using an accidental sampling technique, involving a total of 58 respondents. Data were collected using questionnaires, and data analysis was performed using computer-based statistical analysis with the Gamma test. The results showed a significant relationship between self-concept and quality of life among patients undergoing chemotherapy, with a p-value of 0.000 (p < 0.05). In addition, the correlation coefficient (r) was 0.931, indicating a very strong and positive relationship. These findings suggest that patients with a more positive self-concept tend to have a better quality of life while undergoing chemotherapy. It is recommended that patients improve self-understanding and self-acceptance through active participation in educational and counseling programs provided by healthcare facilities, in order to enhance their quality of life during chemotherapy.
Hubungan Personal Hygiene, Sanitasi Lingkungan, dan Status Gizi Terhadap Infeksi Cacing Usus Di SDN 3 Pringgabaya Kabupaten Lombok Timur Diah Kadek Sulistyawati; Aena Mardiah; Fahriana Azmi
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 5 No. 3 (2026): September: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v5i3.6944

Abstract

Parasitic worm infections in the intestines remain a major public health concern among children, particularly in areas where hygiene practices and environmental cleanliness are still lacking. Primary school-aged children are more susceptible because they often come into direct contact with soil and tend to have suboptimal personal hygiene behaviors. These infections may disrupt the body’s ability to absorb nutrients and can adversely affect overall nutritional status. Several factors are thought to contribute to the risk of infection, including individual hygiene practices, environmental sanitation conditions, and nutritional status. This study was conducted to examine the relationship between personal hygiene, environmental sanitation, and nutritional status with the occurrence of intestinal helminth infections among students of SDN 3 Pringgabaya, East Lombok Regency. The research applied a cross-sectional approach and involved 37 respondents who met predetermined inclusion and exclusion criteria. Information on hygiene practices and environmental sanitation was collected using questionnaires. Nutritional status was assessed through anthropometric measurements based on Body Mass Index for Age (BMI-for-Age), while infection status was determined באמצעות microscopic examination of stool samples. The results indicated that 8 respondents (21.6%) were infected. Most participants demonstrated good personal hygiene (81.1%), adequate environmental sanitation (64.9%), and normal nutritional status (62.2%). Statistical analysis showed a significant relationship between personal hygiene (p=0.000) and environmental sanitation (p=0.001) with the incidence of infection, whereas nutritional status was not significantly associated (p=0.323). Therefore, improving hygiene practices and maintaining proper environmental sanitation are crucial preventive measures against intestinal helminth infections.
Review Artikel: Pengaruh Sistem Emulsi Lipid terhadap Farmakokinetika Obat Lipofili Ghina Salsabila; Candra Dwipayana Hamdin; Karlina Dwi Febrianingsih; Naya Wahyu Anindiya; Febriana Putri Rohmayani; Haulya Razkianita; Siti Maesarah; Sabila Rosyada; Puji Elok Dzakirah
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 5 No. 3 (2026): September: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v5i3.6945

Abstract

Lipophilic drugs have low water solubility and often exhibit inconsistent absorption profiles, which can lead to suboptimal therapeutic outcomes in clinical use. Lipid-based drug delivery systems have emerged as a promising and widely studied formulation strategy because they are able to significantly enhance the solubility, bioavailability, and systemic distribution of lipophilic drugs. This study aims to identify how various lipid emulsion systems modify the pharmacokinetic profile of lipophilic drugs, compare the differences in effects among different types of emulsions, and highlight the key formulation characteristics that contribute to these pharmacokinetic parameter changes. The study was conducted through a comprehensive literature review of national and international scientific articles published between 2015 and 2025. The results indicate that lipid emulsion systems modify pharmacokinetics primarily through increased drug dissolution, accelerated absorption processes, reduced first-pass metabolism, and facilitation of lymphatic transport pathways. These mechanisms consistently result in increased Cmax, AUC, and overall bioavailability. The formulation characteristics that strongly influence these outcomes include nano-sized droplet distribution, lipid type selection, surfactant and co-surfactant composition, amorphous drug form, and the physical stability of the emulsion system.
Hubungan antara Psychosocial Safety Climate dengan Depressive Symptoms pada Karyawan PT X Afifah Nurul Fadilah; Endang Dwiyanti
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 5 No. 3 (2026): September: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v5i3.6955

Abstract

Depressive symptoms in the workplace are an occupational health issue that needs attention. Psychosocial Safety Climate (PSC) is considered one of the key factors that can protect employees’ psychological well-being. This study aims to analyze the relationship between psychosocial safety climate and depressive symptoms among employees of PT X. A quantitative cross-sectional approach was employed, involving total sampling of 30 employees. Psychosocial safety climate was measured using the PSC-12 questionnaire, while depressive symptoms were assessed using the Beck Depression Inventory-II (BDI-II). Data analysis was conducted using the Spearman rank correlation test. The majority of workers were male (53%) and aged between 31–35 years (40%). Most participants were categorized as having mild depression (13 individuals; 43.3%). In terms of psychosocial safety climate, the majority were classified in the high-risk category (15 individuals; 50%). The results of the Spearman correlation test indicated a significant positive relationship between psychosocial safety climate and depressive symptoms (p < 0.001; r = 0.702). This suggests that higher levels of PSC risk are associated with higher levels of depressive symptoms among employees. Therefore, management is recommended to strengthen PSC-related practices and implement workplace-based mental health programs.
Karakteristik Individu dan Stres Kerja pada Operator Unit Produksi di Industri bidang Ketenagalistrikan: Analisis Usia, Masa Kerja, dan Tingkat Pendidikan Sevina Nabilah Khansa; Putri Ayuni Alayyannur
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 5 No. 3 (2026): September: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v5i3.6978

Abstract

Work stress is an occupational health issue that can affect workers’ well-being and job performance. Individual responses to work stress may vary and can be affected by individual characteristics such as age, length of service, and educational level. The relationship between individual characteristics and workstress among operators at PT X was examined in this study. This study used a quantitative descriptive correlational design with a cross-sectional approach. The study was involving 31 operators from the production unit of PT X selected using random sampling. Work stress data were collected using the OSI-R™ questionnaire and analyzed using the Spearman correlation test. Most respondents were aged 45–54 years (42%), had ≥30 years of service (58%), and had a senior high school/vocational education level (61%). Most operators experienced moderate work stress (55%). The analysis age and length of service were significantly related to work stress (p < 0.001), while educational level was not significantly related to work stress (p = 0.518). Age and length of service were associated with work stress among PT X operators, where older workers and those with longer tenure tended to experience lower work stress.

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