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Jurnal Kedokteran Diponegoro
Published by Universitas Diponegoro
ISSN : -     EISSN : 25408844     DOI : -
Core Subject : Health,
Medicine & Pharmacology
JKD : JURNAL KEDOKTERAN DIPONEGORO ( ISSN : 2540-8844 ) adalah jurnal yang berisi tentang artikel bidang kedokteran dan kesehatan karya civitas akademika dari Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang dan peneliti dari luar yang membutuhkan publikasi . JURNAL KEDOKTERAN DIPONEGORO terbit empat kali per tahun. JURNAL KEDOKTERAN DIPONEGORO diterbitkan oleh Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang.
Arjuna Subject : -
Articles 1,040 Documents
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THE CORRELATION BETWEEN CELL OF ORIGIN SUBTYPE WITH OVERALL SURVIVAL OF DIFFUSE LARGE B-CELL LYMPHOMA PATIENTS IN KARIADI GENERAL HOSPITAL SEMARANG Jenifer Marsela Tarius; Hermawan Istiadi; Ika Pawitra Miranti; Intan Rahmania Eka Dini
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 3 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (520.406 KB) | DOI: 10.14710/dmj.v9i3.27504

Abstract

Background: DLBCL is the most common type of NHL in the world. DLBCL based on cell of origin is divided into GCB and non-GCB. The diagnosis of DLBCL has not been routinely done to its cell of origin, and there have not been many studies that discuss the DLBCL subtype and the overall survival of the patients, especially in Kariadi General Hospital. This study aims to determine the correlation of DLBCL cell of origin with the 2-year overall survival of DLBCL patients in Kariadi General Hospital. Methods: This is an observational analytic study of 40 DLBCL patients in Kariadi General Hospital from January to August 2017. The data collection including: age of diagnosis, location, stage and 2-year overall survival. Data analysis used chi square test and Kaplan Meier curve. Results: GCB patients had higher 2-year overall survival than non-GCB subtype significantly (p: 0.047), with a 2-year survival rate of GCB subtype was 66.7% and non-GCB subtype was 31.6%. GCB patients tend to have early stage than non-GCB subtype significantly (p:0.028). Conclusion: DLBCL GCB subtype patients had significantly higher 2-year overall survival therefore it has better prognosis than non-GCB subtype.
PENGARUH PIJAT AKUPUNTUR (ACCUPRESSURE) TELINGA TERHADAP KADAR LEPTIN PADA OBESITAS Ariosta Ariosta; Dwi Retnoningrum; Aryu Candra; Darmawati Ayu Indraswari; Salma S Salma S; Vonny Folanda; Josevaldo Bagus P; Jessica Christanti
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 9, No 4 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (427.214 KB) | DOI: 10.14710/dmj.v9i4.27674

Abstract

Latar Belakang: Obesitas merupakan suatu kelainan metabolik yang disebabkan banyak faktor, salah satu diantranya adalah pola makan dan kadar leptin yang menghambat nafsu makan. Pijat akupunktur pada telinga (acupressure) merupakan salah satu traditional chinese medicine yang dapat mengurangi nafsu makan sehingga berat badan menurun. Penelitian ini berfungsi untuk melihat apakah terdapat pengaruh acupressure terhadap kadar leptin, dan food frequency questionnaire. Metode: Penelitian eksperimental ini menggunakan desain one  group pre and post test design. Sampel penelitian berjumlah 31 sampel pasien obesitas sesuai kriteria BMI menurut Asia. Kadar leptin dan asupan makanan karbohidrat, protein dan lemak sebelum dan sesudah acupressure dihitung dengan menggunakan food frequency questionnaire. Uji normalitas menggunakan uji saphiro wilk. Sampel penelitian adalah pasien obesitas. Uji beda antara kadar leptin sebelum dan sesudah dialkukan acupressure menggunakan uji wilcoxon. Uji beda asupan karbohidrat dan asupan lemak sebelum dan sesudah acupressure menggunakan paired t test, sedangkan asupan protein sebelum dan sesudah acupressure menggunakan uji wilcoxoon. Hasil: Didapatkan penurunan kadar leptin secara bermakna sebelum dan sesudah acupressure sebesar -4,67 ± 6,12 ng/ml dimana p<0,05 dengan uji wilcoxon. Didapatkan perbedaan bermakna asupan karbohidrat dan protein dimana p<0,05, namun tidak didapatkan perbedaan bermakna asupan lemak sebelum dan sesudah acupressure p>0,05. Kesimpulan: Acupresure akan menurunkan kadar leptin seiring dengan penurunan berat badan selain itu akan menurunkan asupan karbohidrat dan protein namun tidak mempengaruhi asupan lemak.
HUBUNGAN INTENSITAS PENGGUNAAN SITUS JEJARING SOSIAL DENGAN KECEMASAN PADA REMAJA (STUDI KASUS SMA N 1 JEPARA DAN SMA N 1 DONOROJO) Aulia Rosma Pramudani; Ari Budi Himawan; Natalia Dewi Wardani; Yanuar Iman Santosa
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 9, No 4 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (486.273 KB) | DOI: 10.14710/dmj.v9i4.27665

Abstract

Latar Belakang: Situs jejaring sosial mempunyai dampak yang negatif dalam kehidupan para remaja. Kecanduan jejaring sosial dapat mengakibatkan efek samping yang cukup besar terhadap hubungan interpersonal, penurunan kinerja, penurunan fisik, hingga kesehatan psikologis seperti kecemasan. Perasaan yang tidak menyenangkan ini umumnya menimbulkan gejala-gejala fisiologis dan gejala-gejala psikologis. Tujuan: Mengetahui adakah hubungan intensitas penggunaan situs jejaring sosial dengan kecemasan pada remaja.  Metode: Penelitian ini merupakan penelitian observasional analitik desain cross sectional. Sebanyak 360 orang siswa dari SMAN 1 Jepara dan SMAN 1 Donorojo. Calon subyek penelitian yang masuk kriteria inklusi dikumpulkan dan dimintai kesediaannya untuk menjadi subyek penelitian dengan mengisi informed consent dengan benar. Kemudian subyek penelitian diminta untuk mengisi kuesioner demografi, kuesioner Social Network Time Usage Scale (SONTUS) dan kuesioner Revised Children’s Manifest Anxiety Scale (RCMAS). Uji statistik yang digunakan adalah uji non parametrik yaitu uji Cramer’s V dan uji Spearman. Hasil: Responden memiliki faktor demografi yang bervariasi. Pada SMAN 1 Jepara, sebanyak 4 responden (2%) memiliki intensitas penggunaan situs jejaring sosial rendah, 106 responden (59%) memiliki intensitas sedang, 70 responden (39%) memiliki intensitas tinggi, sedangkan pada SMAN 1 Donorojo, sebanyak 4 responden (2%) memiliki intensitas penggunaan situs jejaring sosial rendah, 134 responden (74%) memiliki intensitas sedang, 41 responden (23%) memiliki intensitas tinggi dan 1 responden (1%) memiliki intensitas sangat tinggi. Pada SMAN 1 Jepara, terdapat 67 responden (37%) tidak mengalami gangguan cemas dan 113 responden (63%) mengalami kecemasan sedangkan pada SMAN 1 Donorojo, terdapat 79 responden (44%) tidak mengalami gangguan cemas dan 101 responden (58%) mengalami kecemasan. Terbukti adanya hubungan yang signifikan antara intensitas penggunaan situs jejaring sosial dan kecemasan pada mahasiswa tingkat akhir dengan koefisien signifikansi sebesar 0,000 serta koefisien korelasi sebesar 0,254.  Kesimpulan: Terdapat hubungan yang bermakna antara intensitas penggunaan situs jejaring sosial dan kecemasan.
THE DIFFERENCE OF NEUTROPHIL LYMPHOCYTE RATIO (NLR) IN CONVENTIONAL AND ELECTRIC SMOKERS Sarah, Diah Ayu Siti; Naftali, Zulfikar; Yusmawan, Willy; Suprihati, Suprihati
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 3 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (402.527 KB)

Abstract

Background: Smoking is an unhealthy lifestyle causing health problems that may lead to high morbidity and mortality rates. One way to stop smoking habit is by replacing conventional cigarettes with electric cigarettes. Cigarette smoke exposure can trigger an inflammatory reaction that can be measured using Neutrophil Lymphocyte Ratio (NLR). Aim: Proving of NLR in electric smoker are higher than conventional smoker. Method: The research used descriptive analytic design. The number of samples were 34 people, divided into 17 people each group (conventional smoker and electric smoker). The subjects were asked to fill out a questionnaire and their blood samples were taken by 3 cc. Then, the blood samples were tested in a laboratory to obtain NLR values. The data was then analyzed using unpaired T-test.  Result: NLR mean in the conventional smoker group is 1,364 ± 0,28 and 1,791 ± 0,49 in the electric smoker group. The unpaired T-test indicates there is significant difference in the value of NLR between conventional smoker and electric smoker (p=0,005).  Conclusion: NLR in electric smoker are higher than conventional smoke.
THE IMPACT OF BODY MASS INDEX TO ACUTE MYOCARDIAL INFARCTION IN-HOSPITAL PATIENTS MORTALITY RATE IN DR. KARIADI HOSPITAL Indra Adhim Karunia Aji; Andreas Arie Setiawan; Ariosta Ariosta; Setyo Gundi Pramudo
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 3 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (457.454 KB) | DOI: 10.14710/dmj.v9i3.27497

Abstract

Introduction. Populations with high BMI are at risk for cardiovascular disease because these populations usually have high levels of fat in the body. In contrast, there are several studies that prove that body weight below normal BMI also increases cardiovascular disease risk and death. The aim of this study was to determine the impact of BMI on mortality rates of in-hospital patients with acute myocardial infarction at dr. Kariadi Hospital. Methods. This research is a retrospective analytic observational study with cross sectional design. The sample of this study was acute myocardial infarction patients who were undergoing treatment at the RSUP dr. Kariadi between January 2013 - December 2018 complete data on body weight, height, and status of death or survival. Data comparisons were made using fisher exact test with statistical significant p value was less than 0.05. Results. Statistical analysis using fisher exact test showed association between body mass index and mortality rate is not significant (p = 0,258). Age is the only one confounding variable that showed significant association with mortality rate (p =0,032). Relative risk of age is 1.8 with a cutoff at 60 years. Conclusions. Body mass index (BMI) did not have a significant impact on the mortality rate of AMI in-hospital patients at dr. Kariadi Hospital.Keywords: body mass index, acute myocardial infarction, mortality 
BLOOD PRESSURE CORRELATION WITH IN-HOSPITAL MORTALITY ST-ELEVATION MYOCARDIAL INFARCTION PATIENT CASE STUDY IN RSUP DR. KARIADI Agung Satria Winahyu; Ilham Uddin; Sefri Noventi Sofia; Ariosta Ariosta
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 4 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (485.025 KB) | DOI: 10.14710/dmj.v9i4.27670

Abstract

Background: Blood pressure had been suspected to correlate with in-hospital mortality on ST-Elevation Myocardial Infarct (STEMI) patients. Aim: To prove the correlation between blood pressure with short-term in-hospital mortality on STEMI patients. Methods: This study was a retrospective analytic observational qualitative study with a cohort design. The data collecting technique used STEMI patient medical records at the RSUP dr. Kariadi and took blood pressure data when the patients admitted to the hospital, after that divided into three groups, namely hypertension, normotension, and hypotension, then analyze the data on the output of patients alive or dying when they were discharged from the hospital using Fisher exact test.  Results: Hypertension (p=0,428; OR=0,355), Normotension (p = 1; OR=1,267), and Hypotension (p=0,687; OR=1,500) along with hypertension history (p=0,785; OR=1,200) was not correlated with in-hospital mortality of STEMI patient in RSUP dr. Kariadi.  Conclusion: There was no correlation between blood pressure at admission with in-hospital mortality in STEMI patients.
THE EFFECT OF JUMP ROPE TRAINING ON OXIDATIVE STRESS AND PULMONARY FUNCTION AMONG MEDICAL STUDENTS Adhyaksa, Afif Fauzi; Ambarwati, Endang; Supatmo, Yuswo; Marijo, Marijo
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 4 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (617.366 KB) | DOI: 10.14710/dmj.v9i4.27659

Abstract

Background. Physical inactivity has been known as a global public health problem and also becomes an important risk factor for Non-Communicable Disease (NCD). Jump rope training is an example of aerobic exercise that is easily done with simple tools. It also increases pulmonary function and reduces oxidative stress. The objective of the study assessing the effects of jump rope training on oxidative stress and pulmonary function in male medical students of Diponegoro University. Method. This is a quasi-experimental study with 42 male medical students as subjects. The subjects were chosen purposively and divided into two groups using a matched subject design. The treatment group was given jump rope training for 6 weeks, each week consists of three-session exercises. The control group didn’t perform jump rope training. The pulmonary functions measured are Vital Capacity (VC), Forced Vital Capacity (FVC) and Forced expired volume in one second (FEV1) using spirometry, while the oxidative stress level used malondialdehyde (MDA) parameters measured using the thiobarbituric reactive substances method (TBARS). Paired t-test, independent t-test, Wilcoxon, Mann-Whitney, and Spearman test were used for statistical analysis. Results. There was a significant difference in spirometry test and MDA level in the jump rope training group compared to the control with p < 0.001. Spearman’s correlation analysis revealed that MDA levels were not correlated with pulmonary function (p > 0.05). Conclusion. Jump rope training may decline oxidative stress and improve pulmonary function in male medical students of Diponegoro University.
CORRELATIONS BETWEEN SUCCESSFUL THERAPY AND ANXIETY LEVEL OF POST OPERATIVE GLAUCOMA PATIENTS Singgih Pratama; Arief Wildan; Riski Prihatningtias; Fifin Luthfia Rahmi
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 3 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (303.145 KB) | DOI: 10.14710/dmj.v9i3.27505

Abstract

Background : Glaucoma is a disease that can cause damage to the optic nerve. High intraocular pressure is a major risk factor for glaucoma. The main goal of treating glaucoma is to control the disease progression by reducing intraocular pressure to the normal range or in accordance with the target pressure, and unsuccessful treatment can lead to anxiety. Aims : Identifying the correlation between therapeutic success and anxiety levels in post-operative glaucoma patients. Methods : This research used observational analytic method with a cross-sectional design. A total of 34 post-operative glaucoma patients were collected by consecutive sampling at the Eye Outpatient Installation of Dr. Kariadi Hospital Semarang. The anxiety level was assessed using the Taylor Manifest Anxiety Scale (TMAS) questionnaire. Data analysis in the study used the Contingency Coefficient test. Results : A total of 34 glaucoma patients consisted of 17 patients who successfully achieved the target pressure and 17 patients who failed to achieve the target pressure. There was a significant correlation between the success of glaucoma therapy with anxiety levels (p = 0.008) and there was a weak relationship between the two variables (r = 0.471). Conclusion : There is a correlation between therapeutic success and anxiety levels in post-operative glaucoma patients.
GAMBARAN KAPASITAS FUNGSI PARU PADA MASYARAKAT DI SEKITAR PEMBANGKIT LISTRIK TENAGA UAP (PLTU) KABUPATEN JEPARA Diah Rahayu Wulandari; Dodik Pramono; Ari Budi Himawan; Teddy Wahyu Nugroho
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 9, No 4 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (295.371 KB) | DOI: 10.14710/dmj.v9i4.27675

Abstract

Latar Belakang Batubara digunakan sebagai sumber energi langsung maupun tidak langsung, Sebagai energi langsung digunakan antara lain untuk PLTU. Penyakit saluran napas ditemukan secara luas dan berhubungan dengan pajanan tertentu, misalnya debu. Hal itu terjadi karena pembakaran batu bara pada PLTU. Debu batubara mengandung bahan kimia yang dapat mengakibatkan terjadinya penyakit pada paru. Penyakit tersebut banyak muncul pada pekerja atau masyarakat yang berada di lokasi tambang batubara, atau di kawasan yang dilalui pengangkut batubara, karena menghirup debu batubara secara terus-menerus. Metode penelitian penelitian ini merupakan penelitian deskriptif untuk melihat gambaran karakteristik masyarakat dan gambaran kapasitas vital paru masyarakat di sekitar PLTU Kabupaten Jepara. Pemilihan responden dengan cara konsekutif, jumlah responden yang didapat adalah 45 responden. Hasil Penelitian Mayoritas responden berjenis kelamin laki-laki ( 71,1%), lansia (53,3%), tidak berolah raga ( 77,8%), tidak merokok (60%), indeks massa tubuh normal (31,1%), dan berperilaku membuka jendela (53,3%)  dan masyarakat dengan responden yang memiliki kapasitas Vital Paru Normal ( 51,1%), yang memiliki gangguan fungsi paru (48,9%). Gangguan fungsi paru dikategorikan restriksi ringan ( 26,7%), dan restriksi sedang (22,2%).
THE EXISTENCE OF FUNGI AND THE EFFECT OF TERMINAL CLEANSING ON OPERATING ROOM AIRBORNE FUNGI Firdaus, Nadilla Shafa; Farida, Helmia; Hapsari, Rebriarina
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 4 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (594.606 KB) | DOI: 10.14710/dmj.v9i4.27666

Abstract

Background: Fungi is one of the causes of infectious diseases, especially in immunocompromised patients. Surgical site infection (SSI) becomes a major challenge as it is the leading cause of healthcare-associated infection (HAIs). HAIs can be caused by endogenous or exogenous fungi. Exogenous fungi are present in the hospital environment, such as airborne fungi. Fungal contamination of the operating area occurs during surgery or after surgery. The effect of temperature, humidity, the focus of fungal source, and room cleanliness can trigger the growth of fungi in the operating room.  Aim: To analyse the growth of fungal air contamination and its affecting factors in the operating room of a type C hospital. Methods: This study used analytic observational with a cross-sectional design. Total samples were 5 operating rooms that were not in repair. Sampling was using the settle down plate 1/1/1 method. The plates of each replication in each room were 13 plates. The fungal culture was at the temperature of 25⁰C and was observed with LPCB. Measurement of temperature and humidity was using the thermo-hygrometer. The focus of the fungal sources was observed in the ceiling of the operating room. Results: In a total of 5 operating rooms, the Fisher exact test results showed no significant differences between room cleaning and fungal growth in the air (p=0.400). In the primary data, the most fungal growth in operating room number 1 and number 5 was 5 plates. The decline in the number of plate overgrown occurred in the operating room number 1, from 5 plates to 1 plate. The Fisher exact test result showed no significant differences between temperature, humidity, and the focus of fungal source with fungal growth in the air (p=1).  Conclusion: In this study, room cleaning, temperature, humidity, and the focus of the fungal source showed no effect on the fungal growth in the air.

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