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e-Journal Pustaka Kesehatan
Published by Universitas Jember
ISSN : 2355178X     EISSN : 27213218     DOI : -
Core Subject : Health, Science,
Health Professions Library & Information Science
e-Journal “Pustaka Kesehatan” merupakan jurnal elektronik ilmiah berISSN (ISSN: 2355-178X) yang menerbitkan artikel hasil penelitian di bidang kesehatan secara umum meliputi: Kedokteran, Kedokteran Gigi, Kesehatan Masyarakat, Farmasi, dan Ilmu Keperawatan. Artikel yang dikirim belum pernah dipublikasikan atau tidak dalam proses penerbitan dalam jurnal ilmiah lain. e-Journal “Pustaka Kesehatan” diterbitkan tiga kali dalam setahun, yaitu bulan Januari, Mei, dan September.
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Articles 621 Documents
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Pengaruh Permainan Ular Tangga terhadap Pengetahuan dan Sikap dalam Menghadapi Menarche pada Siswi SDN Pringgowirawan 01 Sumberbaru Kabupaten Jember (The effect of snack and ladder game to the knowladge and attitude to confront menarche for the students of elementary school 01 Sumberbaru, Jember) Dini Kurniawati; Devis Yulia Rohmana; Peni Perdani Juliningrum
Pustaka Kesehatan Vol 5 No 1 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Menarche is the beginning of menstruation in young women and information about menarche is needed so that students can prepare themselves to confront menarche. The snake and ladder game is an educative game method that is appropriate for elementary school students. The purpose of this research was conducted to determine the effect of snake and ladder game on knowledge and attitude to confront menarche for elementary school students. This research is quasy experiment with two treatment group pretest-posttest design using 30 respondents with 15 respondents experimental group and 15 respondents comparing group (control). Data were analyzed by using Wilcoxon Signed Rank Test. The result showed that there was increasing knowledge of menarche by 40.1% from the treated group, and positive attitude confront of menarche increased by 46.6% after given intervention (p = 0.001/p <0.05), meaning that H1 was accepted, there are significant differences in knowledge and attitude between pre-test and post-test so the snake and ladder game affects the knowledge and attitude to confront menarche in the treated group. The snake and ladder game can improve knowledge and attitude to confront of menarche and learning method by using snack and ladder game can be one of the media to convey information to the elementary school students. Keywords : menarche, snack and ladder game
Determinasi Inulin dalam Sampel Ekstrak Umbi Dahlia (Dahlia spp L.) yang Ditamam pada Media Tanah dan Polybag dengan Metode KLT- Densitometri Arrofita Ani Sandiya; Yuni Retnaningtyas; Lestyo Wulandari
Pustaka Kesehatan Vol 2 No 2 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Inulin is a polysaccharide , which is composed of fructose units. Inulin is generally found in plants family Compositae, Amirilidaceae, and Poaceae. Benefits inulin is as bifidogenic body, stimulate the immune system , relieve constipation , reduce the risk of osteoporosis . Inulin can be consumed alone as a prebiotic supplement. The purpose of this study was to develop a method for determination of inulin TLC-Densitometry in dahlia tuber extract samples (Dahlia spp L.) grown in soil media and polybag . Determination of inulin as a method of TLC densitometry using the stationary phase TLC plates Silica Gel F254, mobile phase = acetic acid glacial p.a: methanol p.a: aquabides sterille (v/v/v/v) (0,5:7,5:2) , solvent = Aquabides sterille: Ethanol 96 % p.a (3:1) v/v, apparition stains is mixed aniline in acetone 1% v/v:diphenylamine in acetone 10% b/v:phosphoric acid (5:5:1), and the wavelength () 380 nm . Validation of the method showed that the research procedures performed has had good linearity with a coefficient correlation 0.996 and Vx0 value 4.850%. This method also gives good accuracy and precision that is the percent recovery of inulin at 99,96%±0,39%. and the value of repeatability = 0,993% < 2,7% and intermediate precision RSD = 0,554% < 2,7% with limits of detection (LOD) and limit of quantitation (LOQ), respectively, 71,03 ng/spot and 236.76 ng/spot. The results showed levels of inulin in the dahlia tuber extract soil planted mediated by 86.256%±0.669% (%b/b±RSD%), and dahlia tubers grown polybag mediated by 76.146%±1.657% (%b/b±RSD%).
Pengembangan Label Pintar untuk Indikator Kesegaran Daging Sapi pada Kemasan Arjun Nurfawaidi; Bambang Kuswandi; Lestyo Wulandari
Pustaka Kesehatan Vol 6 No 2 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i2.7560

Abstract

Meat is a high nutritional food that rich of protein, fat, and sugar. Smart label has been applied as a beef freshness detector. Two types of pH indicator have been used i.e bromocresol purple (BCP) and methyl red (MR) as dual indicator freshness. The objective of this research was to determine the beef freshness using smart label at room temperature. The color change of the smart label was examined by imageJ software to determine the freshness degree using the mean RGB value. The beef was examined every 2 hours for pH and total volatile base (TVB-N) analysis during the 24 hours storage at room temperature. The result showed that color indicator will change according to the beef freshness, bromocresol purple turned from yellow to purple (mean RGB 171.465 ± 1.122) and methyl red turned from red to yellow (mean RGB 162.082 ± 1.315). The beef freshness at room temperature decreased as the pH increase from 5.61 to 6.23 along with the color change of smart label. Furthermore, the color would change when 0.022 %N of TVB-N has been reached. Therefore, the beef freshness can be determined by using smart label based on dual indicator of bromocresol purple and methyl red in room temperature. Keywords: beef freshness, smart label, pH, TVB
Penetapan Kadar Inulin dalam Ekstrak Umbi Dahlia variabilis dan Dahlia pinnata dengan Metode KLT Densitometri (Determination of Inulin Content in Dahlia variabilis and Dahlia pinnata Tuber Extract by TLC Densitometry Method) Khoirun Nisa'; Yuni Retnaningtyas; Nia Kristiningrum
Pustaka Kesehatan Vol 3 No 2 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Inulin is a polymer which have many benefits for health and used widely for food. The absence of research on determination of inulin content in dahlia tuber extract from different species, made this study very important to do. The purpose of this study was to determine the inulin content in dahlia tuber extract from different species. So it can be known the most effective type of dahlia to be the major source of inulin production. The method used in this study was TLC densitometry. The result showed that the inulin content in Dahlia variabilis tuber extract was 73.93 ± 1.209%, and the inulin content in Dahlia pinnata tuber extract was 66.76 ± 0.572%. The inulin content in Dahlia variabilis and Dahlia pinnata tuber extract were significantly different. Keywords: inulin, dahlia tuber, Dahlia variabilis, Dahlia pinnata, TLC densitometry
Analisis Nilai Laju Endap Darah pada Pasien Sindrom Koroner Akut dan Stable Angina di RSD dr. Soebandi Jember (The Erythrocyte Sedimentation Rate Analysis in Acute Coronary Syndrome and Stable Angina Patients at dr. Soebandi General Hospital) Rizki Nur Fitria; Suryono Suryono; Rini Riyanti
Pustaka Kesehatan Vol 5 No 2 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Erythrocyte sedimentation rate (ESR) is non-specific blood tests that can be used as a marker of chronic inflammation. Some proteins that affect the erythrocyte sedimentation rate are fibrinogen, lipoprotein, and immunoglobulins. These proteins elevate in patients with atherosclerosis and acute coronary syndrome. This study aimed to determine the relationship between erythrocyte sedimentation rate and the incidence of acute coronary syndrome and stable angina at dr. Soebandi General Hospital Jember. This analytic observasional study using cross-sectional design.This study used 40 samples, divided into four groups; stable angina, UA, NSTEMI, and STEMI. The average value of ESR were 12,1mm/h, 20,7mm/h, 28,9mm/h, and 25,3mm/h for stable angina, UA, NSTEMI, and STEMI, respectively. Kolmogorov-Smirnov statistical test showed significant difference between groups(p=0.001). It indicated that there was relationship between erythrocyte sedimentation rate and the incidence of acute coronary syndrome and stable angina in dr. Soebandi General Hospital Jember. Keywords: erythrocyte sedimentation rate, acute coronary syndrome, stable angina
Uji Aktivitas Antibakteri Ekstrak Metanol dan Fraksi Daun Kenikir (Cosmos caudatus Kunth) terhadap Salmonella typhi Achmad Syarifudin Noor; Bawon Triatmoko; Nuri Nuri
Pustaka Kesehatan Vol 8 No 3 (2020): Volume 8 No. 3, 2020
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v8i3.13008

Abstract

The leaves of kenikir are known to have many benefits, one of which can be used as medicine. Kenikir leaves are reported to have antibacterial activity against the bacteria Salmonella typhi (S.typhi). S. typhi is a bacterium that causes typhoid fever. Typhoid fever is still an endemic disease in Asian countries, especially Indonesia. Typhoid fever became the third largest disease in Indonesia in 2010. The study related to the antibacterial activity of kenikir leaf fraction to S. typhi has never been reported. Therefore, it is necessary to conduct research related to the antibacterial activity of extracts and leaf fractions of kenikir to compare their potential against S. typhi. The study was conducted using the disk diffusion method using 5 series of concentrations namely 5%, 10%, 15%, 20%, and 30%. Tests were carried out on methanol extract, hexane, ethyl acetate, and methanol-water fraction. The results showed that highest inhibition zone diameter is 7,75 mm which is reached by methanol extract. The order of the highest inhibiting zone diameter are extract, hexane, ethyl acetate, and methanol-water fraction.
Label Pintar untuk Pemonitoran Kesegaran Daging Ayam pada Kemasan Novialda Nitiyacassari; Bambang Kuswandi; Dian Agung Pangaribowo
Pustaka Kesehatan Vol 9 No 2 (2021): Volume 9 No.2, 2021
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v9i2.10974

Abstract

Chicken meat is one of the commodities consumed by most Indonesian people and has a pH range of 5,5 – 6,0. The smart label has been applied as a chicken meat freshness detector. As dual indicator freshness, two pH indicators have been used, i.e., bromothymol blue (BTB) and methyl red (MR). The objective of this research was to determine chicken meat freshness using a smart label at room temperature. The color change of the smart label was examined by ImageJ software to determine freshness degree using the mean RGB value. The chicken meat was examined every 2 hours for pH and TVB analysis during the 24 hours storage at room temperature. The result showed that color indicator would change according to chicken meat freshness, BTB turned from yellow to blue (mean RGB 210,591 ± 0,376), and MR turned from red to yellow (mean RGB 208,146 ± 0,390). Chicken meat freshness at room temperature decreased as pH increase from 5,68 to 6,11 along with a color change of smart label. Furthermore, the color would change when 0.022 %N of TVB has been reached. Therefore, chicken meat freshness can be determined by using a smart label based on a dual indicator of bromothymol blue and methyl red at room temperature.
Pengembangan Biosensor Berbasis Kertas untuk Penentuan Aktivitas Antihiperlipidemia Pada Sampel Ekstrak Tanaman Vinda Aisya Vira; Bambang Kuswandi; Indah Purnama Sary
Pustaka Kesehatan Vol 9 No 2 (2021): Volume 9 No.2, 2021
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v9i2.19051

Abstract

A biosensor is an alternative method to determine the antihyperlipidemic activity to be more simple, effective, and efficient in various herbal extracts. This study aimed to develop a biosensor with the principle of pancreatic lipase enzyme inhibition in paper microzone plates using Whatman filter paper for the matrix, 200 unit/mL of lipase enzyme solution, 1% extract, and 80 mM p-NPB substrate. This paper-based biosensor method shows results that fulfilled the several characterizations, that are the 30 min of the incubation time; linearity using 7 standards orlistat concentrations of 5-35 mg/mL with the regression equation of Y= 22.09585 + 2.170514X, correlation coefficient value (r)= 0.9996745, Vx0= 1.509906%, Xp= 1.572533 mg/mL; LOD and LOQ are 1,573 mg/mL and 4,718 mg/mL; precision with RSD value of 2.545%; accuracy with % recovery value of 99.222%; biosensor usage time after storage remained stable for 3 days at chiller temperatures and for 45 minutes at room temperature. The paper-based biosensor can be an alternative method for detecting antihyperlipidemic activity in plant extracts as same as UV-Vis spectrophotometry method.
Optimasi Hidroksipropil Metilselulosa dan Polivinil Pirolidon dalam Sediaan Mucoadhesive Buccal Film Diltiazem Hidroklorida Lusia Oktora Ruma Kumala Sari; Septi Sudianingsih; Yudi Wicaksono
Pustaka Kesehatan Vol 9 No 1 (2021): Volume 9 No.1, 2021
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v9i1.12228

Abstract

Diltiazem HCl is a class of benzodiazepine calcium channel blockers used to treat angina pectoris, arrhythmias, and hypertension. Diltiazem HCl improves first-pass metabolism, a short half time of 3-5 hours, and bioavailability of diltiazem for oral administration of about 40%. Mucoadhesive buccal film diltiazem HCl releases the drug to the buccal mucosa, so the first pass metabolism can be avoided because of its absorption through the venous system that flows from the cheek. This study aimed to study HPMC polymers and polyvinyl pyrrolidone (PVP) polymers on swelling index, residence time, mucoadhesive strength of mucoadhesive buccal film diltiazem HCl, FTIR, and drug release. The prepared film was evaluated for swelling index, mucoadhesive strength, and mucoadhesive residence time. The optimal amount for HPMC was 35 mg, and PVP was 15 mg. The combination of polymers with this amount can produce a swelling index was 3,00, mucoadhesive strength was 41,87 gF, and mucoadhesive residence time was 330,66. FTIR test indicated that there was no interaction between active function clusters of Diltiazem HCl and other excipients. The release of the optimum formula in the 360th minute was about 97.847%, following in the zero-order release model and Higuchi.
Efektivitas Ekstrak Black Garlic dalam Menghambat Pertumbuhan Candida albicans Ratih Iswari Ningtias; Dyah Indartin Setyowati; Ari Tri Wanodyo Handayani
Pustaka Kesehatan Vol 8 No 3 (2020): Volume 8 No. 3, 2020
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v8i3.12990

Abstract

Black garlic has many properties naturally can be used as an antifungi. This study aims to determine the effectiveness of Black garlic extract in inhibiting the growth of Candida albicans and knowing the Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal Concentration (MFC) of Black garlic extract against Candida albicans. This study used 5 groups of Black garlic extract concentration, namely 75%, 50%, 25%, 12.5%, and positive controls, with 5 replications. Extraction was carried out using maceration method with 96% ethanol solvent, while the antifungal test was carried out by liquid dilution method. MIC was determined by observing the turbidity and clarity of each test solution and compared to the control solution. MFC was determined by observing the presence or absence of fungi colonies growing on Sabouraud Dextrosa Agar (SDA) media after incubation for 24 hours. The results of the study carried out the Kruskall-Wallis test showed a significance value (p <0.05) which means that there were significant differences in all groups. In the Mann-Whitney test showed a significance value (p <0.05) which means there are differences between treatment groups. The conclusion is that Black garlic extract has the ability to antifungal with MIC at a concentration of 50% and MFC at a concentration of 75%.

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