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Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science)
Published by Universitas Ahmad Dahlan
ISSN : 14127946     EISSN : 25035223     DOI : 10.12928
Core Subject : Health, Science,
Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology
Media Farmasi is a scientific journal published by the University of Ahmad Dahlan worked closely with Ikatan Apoteker Indonesia (IAI). Media Farmasi published two times a year, namely in March and September since 2002 with ISSN 1412-7946 and e-ISSN 2503-5223. The article published in the Journal Media Farmasi selected by editors and reviewed by the reviewer. Articles published in Media Farmasi must not be published in other journals or have been previously published. Media Farmasi publishes a review article, original article, as well as short communication in all scopes of Pharmaceutical Science.
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Articles 445 Documents
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The Potential of Sugarcane Bagasse (Saccharum officinarum Linn.) as a Basic Ingredient for Making Cosmetics and Its Effectiveness as an Exfoliator and Skin Moisturizer Suhesti, Iin; Sari, Yunita Dian Permata; Oktofiani, Fauziyah; Janah, Aprillia Nurul
Media Farmasi: Jurnal Ilmu Farmasi Vol. 21 No. 1: March 2024
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v21i1.27915

Abstract

Sugarcane bagasse (Saccharum officinarum Linn.) contains most of the phenolic compounds including gallic acid, ferulic acid, epicatechin, quercetin, and kaempferol. Various phenolic compounds contained in sugarcane bagasse, especially phenolic acids, have important bioactivity for the cosmetics industry. The aim of this research is to determine the potential of sugarcane bagasse as an active ingredient in cosmetics and its effectiveness as an exfoliator and skin moisturizer. This research method is experimental, using sugarcane bagasse samples with concentrations of 1%, 3% and 5%. The results of phytochemical screening showed that sugarcane bagasse contains phenolic compounds, flavonoids and phytosterols. Based on the research results, sugarcane bagasse exfoliating gel at concentrations of 1%, 3%, and 5% increased skin tone respectively, namely 1.00 ± 0.67; 0.40±0.49; and 0.30 ± 0.39. Sugarcane bagasse moisturizing gel at concentrations of 1%, 3%, and 5% had a percent increase in skin water content, respectively, namely 6.92 ± 11.094; 2.72±10.21; and 3.36 ± 6.49. Based on SPSS analysis, it is known that variations in the concentration of bagasse extract and the time of use have a significant effect on increasing skin tone. Meanwhile, variations in the concentration of bagasse extract did not have a significant effect on increasing skin water content. However, the time of use has a significant effect on the increase in skin water content. So, it can be concluded that sugarcane bagasse extract has the potential to be an active ingredient in making cosmetics and is effective as an exfoliator and skin moisturizer.
Identification of Biomarker for Stunting Through Prioritization of Gene-Assosiated Variants Wibowo, Anisa Devi Kharisma; Puspitaningrum, Anisa Nova; Ma’ruf, Muhammad; Irham, Lalu Muhammad; Supadmi, Woro; Kartikasari, Ayu Lifia Nur; Adikusuma, Wirawan; Chong, Rockie; Firman, Firman; Nugraha, Media Fitri Isma Isma; Siswanto, Lalu Muhammad Harmain; Khairi, Sabiah; Pranata, Satria
Media Farmasi: Jurnal Ilmu Farmasi Vol. 21 No. 1: March 2024
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v21i1.28297

Abstract

Stunting is a condition of impaired growth and development in children due to chronic nutritional disorders or infections. The risk factor for stunting is dominated by disease during 1000 days of life. The incidence of stunting in Indonesia is 21.6%, according to the Indonesian Nutrition Status Survey (SSGI) results. This study aimed to identify stunting biomarkers based on the priority scoring of gene variants. Identification of stunting risk genes used the Genome-Wide Association Studies (GWAS) approach and Haploreg v4.1. We found 33 genes that identifies as stunting risk gene. And then, we prioritize based on two functional annotation categories: missense-nonsense and cis-expression quantitative trait loci (cis-eQTL). Our analysis found 4 genes as biological stunting risk genes: MTRR, TTF1, CASP1, and CARD17. This research demonstrates the integration of genomic variants and bioinformatics approaches to reveal biological insights for stunting.
Optimization of Halal Capsule Shell Combination of Amylopectin of Cassava (Manihot esculenta) Pell and Caragenan of Euchema cottoni Pratiwi, Arika Putri; Nur Hazlia, Syarifah; Hartinah Yulianto, Siti; Shifa Syururin, Wakhidatus; Marfu'ah, Nurul
Media Farmasi: Jurnal Ilmu Farmasi Vol. 22 No. 2 (2025): September 2025
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v22i2.29640

Abstract

Gelatin, a primary material for capsule shells, is predominantly sourced from pigs, raising significant concerns regarding its halal status for Muslim consumers. Therefore, identifying halal and sustainable alternatives to gelatin is crucial for the pharmaceutical industry. This study aimed to formulate and evaluate halal capsule shell preparations combining amylopectin from cassava (Manihot esculenta) peel starch and carrageenan from Euchema cottoni. The research utilized an experimental quantitative design with five formulations (F1–F5) based on varying amylopectin: carrageenan concentrations, namely 0.5%:3% (F1), 1%:3% (F2), 1.5%:3% (F3), 0%:3% (F4), and 3%:0% (F5). The capsule shells were assessed through specification tests, water content, ash content, and disintegration time. Data were analyzed using one-way ANOVA in SPSS version 26.0 at a 95% confidence level. The results showed that all formulations met the standards for water content (20–60%), ash content (<5%), and disintegration time (<30 minutes) based on PT. Kapsulindo Indonesia and the Indonesian Pharmacopoeia. However, none of the formulations fully met the specifications for capsule body diameter, cap diameter, and total length, primarily due to manual molding limitations. Among the five formulations, F3 demonstrated the closest conformity to standard physical parameters. Statistical analysis indicated that variations in the concentration of cassava peel starch and Euchema cottoni carrageenan significantly influenced capsule shell specifications, moisture content, and disintegration time (p<0.05), while having no significant effect on ash content (p>0.05). In conclusion, the combination of cassava peel amylopectin and Euchema cottoni carrageenan shows promising potential as a halal and eco-friendly alternative to gelatin-based capsule shells. Further optimization using automated molding systems is recommended to achieve standardized dimensions for commercial application.
Association between Hormonal Contraceptive Use and Hypertension Risk among Reproductive-Age Women: A Cross-sectional Study at Cileungsi Public Health Center, Indonesia Nafara Maharani Itamy, Defa; Rahmi, Eldiza Puji; Luthfiyani Citra Pradana, Dhigna; Farida Muti, Annisa
Media Farmasi: Jurnal Ilmu Farmasi Vol. 22 No. 2 (2025): September 2025
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v22i2.31400

Abstract

Hypertension remains a major public health problem that may be influenced by hormonal contraceptive use, particularly oral and injectable methods commonly used by women of reproductive age. These contraceptives have raised concerns about their potential impact on blood pressure regulation. This study aimed to investigate the association between hormonal contraceptive use and the occurrence of hypertension among women of reproductive age at the Cileungsi Public Health Centre, Bogor Regency, Indonesia. A cross-sectional study was conducted in 2024 using retrospectively collected medical record data of all hormonal contraceptive users at the facility. Total sampling was applied, and data on contraceptive type, duration of use, age, parity, and the most recent blood pressure readings were analyzed. The chi-square test was employed to examine associations between hormonal contraceptive characteristics and hypertension, with a significance level set at p < 0.05. The results revealed a significant association between contraceptive type and hypertension (p = 0.01, OR = 0.27), showing that users of oral contraceptive pills were more likely to develop hypertension than injectable users. Duration of use (p = 0.03, OR = 3.06), age (p = 0.04, OR = 0.12), and parity (p = 0.01, OR = 0.21) were also significantly associated with hypertension. Women aged ≥45 years, those with longer contraceptive use, and multiparous users exhibited a higher risk of elevated blood pressure. These findings highlight that both contraceptive-related and demographic factors contribute to hypertension risk among hormonal contraceptive users. Regular blood pressure monitoring and individualized counseling are essential, especially for oral and long-term users. This study contributes local evidence supporting safer contraceptive practices and cardiovascular risk management within primary healthcare settings.
Estimating the Economic Value and Determining Factors of Unused Medicines Among Households in Cibarusah District, Bekasi Regency Rozak, Abdul; Priyanto, Priyanto; Khaira Rusdi, Numlil
Media Farmasi: Jurnal Ilmu Farmasi Vol. 22 No. 2 (2025): September 2025
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v22i2.31418

Abstract

The accumulation of unused and expired medicines in households poses significant economic, health, and environmental challenges. This study aimed to estimate the economic value of unused medicines and identify factors contributing to their accumulation among households in the Cibarusah District, Bekasi Regency, Indonesia. A cross-sectional survey was conducted from May to June 2025 involving 354 households selected using a convenience sampling approach. Data were collected through structured, face-to-face interviews with validated questionnaires and analyzed descriptively using Microsoft Excel 2021 and SPSS version 29. Results showed that 71.5% of households stored unused medicines, representing an estimated total economic value of IDR 25,271,179, or an average loss of IDR 99,886 per household. Expired medicines accounted for 28.5% of all stored items, with a mean value of IDR 114,897 per household. Analgesics, antipyretics, nonsteroidal anti-inflammatory drugs (NSAIDs), and antigout agents were the most frequently stored drug classes (20.1%), followed by gastrointestinal medicines (15.2%). The primary reasons for medicine accumulation were recovery from illness (70.9%), drug ineffectiveness (15.8%), and expiration (28.5%). Most respondents were female (67.2%), aged 36–55 years, and had completed secondary education. When extrapolated to all 32,515 households in Cibarusah District, the potential economic loss due to unused medicines reached approximately IDR 1.18 billion. This study highlights the substantial economic burden associated with household medicine storage and the need for improved public awareness of rational medicine use. Strengthening educational programs, involving community pharmacists in household medicine management, and establishing structured medicine take-back systems are essential to reduce pharmaceutical waste and its economic impact. These findings contribute valuable local evidence to support national strategies for promoting sustainable and responsible medicine use in Indonesia.

Page 45 of 45 | Total Record : 445

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