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INDONESIA
Berkala Ilmu Kesehatan Kulit dan Kelamin
Published by Universitas Airlangga
ISSN : 19784279     EISSN : 25494082     DOI : 10.20473
Core Subject : Health, Science,
Immunology & microbiology Public Health
Arjuna Subject : -
Articles 505 Documents
 34   35   36   37   38 
Validity and Reliability Test of Vitiligo Quality of Life Index (VitiQoL) Indonesian Version in Vitiligo Patients Jeffrey Giantoro; Fajar Waskito; Sunardi Radiono
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 1 (2022): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.1.2022.52-58

Abstract

Background: Vitiligo is a multifactorial skin disorder that causes depigmentation. Vitiligo can affect a patient's quality of life due to aesthetic issue. The prevalence of vitiligo in the world is 0.5 – 1.0%. An instrument for measuring the quality of life that is specific to vitiligo patients in Indonesia is required. Purpose: This study aims to translate the Vitiligo Specific Quality of Life (VitiQoL) questionnaire into Indonesian: and assess the validity and reliability of the Indonesian language VitiQoL as a quality of life instrument. Methods: An observational method with analytical survey and cross-sectional approach was conducted on 48 vitiligo patients at Sardjito General Hospital Yogyakarta in May – September 2021. The research was carried out in 3 stages. The first stage was the translation of VitiQoL into Indonesian and then back into English. The second and third stages were measuring the validity and reliability of the VitiQoL Indonesian version. Result: The validity test using Pearson product moment showed that the average correlation coefficient for each question is 0.683. Reliability test using Cronbach's alpha of 0.924 VitiQoL. VitiQoL has 3 domains, namely limited participation, stigma, and behavior. The correlation of each domain has a value range of 0.756 - 0.918 with a variation of Cronbach's alpha value per item ranging from 0.808 - 0.89. The limited participation domain (84.2%) has the largest contribution to the value of quality of life. Conclusion: The Indonesian language VitiQoL as an instrument with good validity and reliability can be used to measure the quality of life of vitiligo patients in Indonesia.
Cat Contact as A Risk Factor for Tinea Capitis Infection Evy Ervianti; Addia Salsabila; Yuri Widia; Arthur Pohan Kawilarang
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 1 (2022): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.1.2022.1-4

Abstract

Background: Tinea capitis (TC) is common infection caused by dermatophytes on the scalp. Cat contact is one of the TC risk factors. Microsporum canis is the most abundant fungi in cats and humans as a zoophilic infection. Cats and carrier cats can infect humans, mostly children. Purpose: To evaluate cat contact as a risk factor for TC patients at the Dermatology and Venereology Outpatients Unit of Dr. Soetomo General Academic Hospital Surabaya in January 2017 - December 2018. Methods: A retrospective study by observation and recording data. The results obtained as a result of the data recap were then processed using tabulation to obtain conclusions. Result: The results obtained from TC cases in 2017 and 2018 are 20 patients. The results were cat contact in 9 patients (45%), aged > 5 years (55,6%), male (55,6%), and lived in Surabaya (88,9%), hair loss (88,9%), crust (100%), M. canis in culture (55,6%), Grey patch type (55,6%), combination of oral Griseofulvin and Ketoconazole 2% scalp solution (88,9%), and patients’ follow up (44,4%). Discussion: More people keeping cats will increase the risk of being infected with feline dermatophytosis. Combination therapy is the best treatment for M. canis. It is important to educate parents to be careful with pet cats that can become carriers. Conclusion: Cat contact was positive in almost half patients, mostly in a male and > 5 years old. The most common signs and symptoms were crust and hair loss, and grey patch.
Epidemiology of Leprosy in Indonesia: a Retrospective Study Lubis, Ramona Sari; Anum, Qaira; Argentina, Fifa; Menaldi, Sri Linuwih; Gunawan, Hendra; Yuniati, Renni; Mulianto, Nur Rachmat; Siswati, Agnes Sri; Widasmara, Dhelya; Rusyati, Luh Made Mas; Mamuaja, Enricco Hendra; Muchtar, Vitayani; Cita Rosita Sigit Prakoeswa; Agusni, Regitta Indira; Bagus Haryo Kusumaputra; Medhi Denisa Alinda; Listiawan, Muhammad Yulianto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 1 (2022): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.1.2022.29-35

Abstract

Background: According to WHO data, the number of new cases of leprosy has decreased in 2019. However, Indonesia continues to provide a significant number of cases. According to statistics, India, Brazil, and Indonesia account for 79 percent of all instances. Purpose: This study aims to describe the profile of leprosy patients, and involves all Dermatology and Venereology Academic Hospitals in Indonesia. Methods: This study was a retrospective study of 2461 patients from Dermatology and Venereology Outpatient Clinic at 13 Academic Hospitals in Indonesia between January 2018 and December 2020. Result: Subjects in this study were dominated by males (66.8%) and aged > 14 years (95.3%). The most common type of leprosy was multibacillary (MB) (86.2%), and erythema nodosum leprosum (ENL) was the most leprosy reaction (20.3%). Majority of the subjects experienced disability in the hands (26.6%), in grade 1. Conclusion: Leprosy cases in Indonesia are mostly experienced by adult males. The most common type of leprosy is MB, with ENL being the most common leprosy reaction. Grade 1 disability is the most prevalent, therefore proper education is necessary to keep patients from progressing to grade 2 disability.
The Difference of Serum Vitamin E Levels between Adolescent Patients with and without Acne Vulgaris Wahyunita Desi Ratnaningtyas; Sawitri Sawitri; Dwi Murtiastutik; Afif Nurul Hidayati
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 32 No. 1 (2020): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V32.1.2020.40-47

Abstract

Background: Acne vulgaris (AV) is a chronic inflammatory disease of the pilosebaceous unit, particularly among adolescents. The pathogenesis of AV is multifactorial, developing research studies  the role of free radicals and antioxidants imbalance that cause oxidative stress in AV. The main antioxidant found in the skin is vitamin E, which functions as a protector against lipid peroxide. Purpose: To compare serum vitamin E levels in adolescents with AV and healthy adolescents without AV (controls). Methods: This is a cross-sectional observational analytic study that involved 17 adolescents with AV and 17 controls in Dermatology and Venereology Outpatient Clinic Dr. Soetomo General Academic Hospital Surabaya. The subjects have met the inclusion and exclusion criterias. Result: The mean of vitamin E level in adolescent patients with AV was 7.8 ± 1.07 mg/mL and 10 ± 1.06 mg/mL in controls with the p-value in this study was p = 0.0001. Conclusion:  It was found that serum vitamin E levels in adolescent AV patients were significantly lower than the controls. Further research is required to find out more about the role of antioxidants in the pathogenesis of AV.
Expression of Melan-A in Depigmented Skin of Vitiligo Patients Tjokorde Istri Nindya Vaniary; M. Yulianto Listiawan; Dwi Murtiastutik
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 32 No. 1 (2020): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V32.1.2020.17-20

Abstract

Background: Vitiligo is an acquired and commonly found pigmentation disorder characterized by milky-white patches on the skin, hair, and mucosa due to melanocyte damage. The cause of vitiligo is still unclear. A study proves that cell-mediated immunity plays a role in the pathogenesis of vitiligo. Melan-A is a melanoma-related antigen that is recognized by autologous cytotoxic T cells and one of the critical markers for detecting melanocytes. Objective: To evaluate the expression of Melan-A in depigmented lesions of vitiligo patients. Methods: A descriptive study aimed to describe the expression of Melan-A in the depigmented skin of vitiligo patients at the Dermatovenerology Outpatient Clinic Cosmetic Division of Academic General Hospital Dr. Soetomo Surabaya. Eleven study subjects were selected through a sequence of selection. Results: Melan-A expression in the depigmented skin of vitiligo patients was lower than the average. This result was found in 6 (54.55%) out of 11 patients. Conclusion: Melan-A expressions on depigmented skins of vitiligo patients are generally below the average value; therefore, adequate intervention is needed to increase the Melan-A expression.
Infantile Hemangioma: A Retrospective Study Eva Lydiawati; Iskandar Zulkarnain
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 32 No. 1 (2020): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V32.1.2020.21-26

Abstract

Background: Infantile Hemangioma (IH) is a benign vascular neoplasm and most commonly found in newborns. IH appears in the first few weeks of life and mostly resolve immediately. Early recognition of symptoms, diagnosis, and therapy has an important role in determining the prognosis of this condition. Purpose: The purpose of this study is to evaluate the clinical features of new IH patients in the Pediatric Dermatology Division of the Dermatology & Venereology Department outpatient clinic of Dr. Soetomo General Hospital Surabaya in 2008-2017. Methods: This is a retrospective descriptive study from the medical records of new IH patients over a period of 10 years (2008-2017). Results: A total of 84 new IH patients were observed in this study. The data showed that: the most age group was 0-1 year old (71.43%), female (63.1%), and no family history of a similar condition (94.05%). The most common complaint reported was the presence of bumps (59.52%). Most complaints occurred before the patients turned one year old (89.29%) and involved the facial region (58.33%). From the clinical features, the most frequent skin lesions were macules (35.36%). In addition, there was a combination of macular and nodular lesions in 28.13% of patients. The most widely used therapy is laser modality found in 55.45% of patients. Conclusion: Clinical features of IH patients, in accordance with the theory and treatment choices, dependent on the patients’ conditions and clinical manifestations of the disease. 
Retrospective Study: Malassezia Folliculitis Profile Putri Intan Primasari; Evy Ervianti
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 32 No. 1 (2020): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V32.1.2020.48-54

Abstract

Background: Malassezia folliculitis (MF) is a chronic infectious disease of pilosebaceous follicles caused by Malassezia sp. Clinical features of MF include erythematous papules and itchy perifollicular pustules, especially on the upper body, neck, upper arms, and face. The disease is usually reported on adolescents. Objective: To evaluate the profile of MF patients in four years (2014-2017) period in the Mycology Division of  Dermatovenerology Outpatient Clinic of Dr. Soetomo General Academic Hospital Surabaya. Methods: This study was a retrospective study to examine the medical records of MF patients in the Mycology Division of Dermatovenerology Outpatient Clinic General Academic Hospital Dr. Soetomo Surabaya from January 2014 to December 2017. Results: The number of new MF patient visits during 2014-2017 was 196 patients, and the average annual visit was 55 patients in 2014, 49 patients in 2015, 65 patients in 2016, and 27 patients in 2017. The majority of patients were males, were aged 15-24 years old. The chief complaint was reddish papules accompanied by moderate itching in the predilection area and most often found in the upper body. The Wood's lamp examination revealed greenish-yellow color, and 20% KOH examination showed spores. Most systemic therapies was ketoconazole and tretinoin 0.05% cream for topical therapy. Conclusions: There  was  a decrease in the number of MF patients. The diagnoses of MF were based on history taking, physical examination, 20% KOH, and Wood's lamp.
Scabies in Children: A Retrospective Study Retha Retha; Sawitri Sawitri
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 32 No. 1 (2020): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V32.1.2020.55-61

Abstract

Background: Scabies is a skin disease in humans and is caused by Sarcoptes scabiei mite. It burrows into the skin and is transmitted through close physical contact. The common symptom is itchiness, mainly occur at night, along with a history of itch from family members or friends with whom the patients might have close physical contact before. Scabies is still a concerning health problem for the majority of poor and developing countries. Purpose: To evaluate the profile of newly-admitted children scabies patients. Methods: This study retrospectively evaluated the medical records of subjects with scabies in the Children Dermatology Division, Dermatology and Venereology Department of Dr. Soetomo General Academic Hospital, Surabaya, between January 2012 and December 2014. Results: There were 545 patients with scabies (33.6% from Children Dermatology Division visit and 3.2% from overall outpatient clinic visit), mainly consisted of children aged 5-14 years old (69%), and mostly males (62.6%). The most common symptom was itchiness (70.28%), most patient sought treatment after the complaint have been persisted for more than 30 days (51.7%), and 66.4% patients have family members with similar complaint. Most of the lesions were found on the hands (60.37%), mostly as papules (73.2%). Almost all of them did not undergo a skin scraping examination (99.1%). The most common therapy combination was permethrin 5% and oral antihistamine (49.7%). Conclusions: This profile on scabies patients was expected to aid in improving scabies treatment in the future.
Chickenpox Mimicking Monkeypox in Adult with Diabetes Mellitus and Acute Kidney Injury: Diagnosis and Management Maya Wardiana; Rahmadewi Rahmadewi; Dwi Murtiastutik; Sawitri Sawitri; Damayanti Damayanti
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 3 (2021): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.3.2021.213-223

Abstract

Background: Chickenpox caused by the varicella-zoster virus (VZV) in diabetes mellitus patients might exhibit similar clinical features with monkeypox, caused by monkeypox virus (MPXV). In May 2019, Singapore notified World Health Organization (WHO) of one laboratory-confirmed case of monkeypox. Considering Singapore is located near Indonesia, awareness about the possibility of an outbreak in Indonesia should be raised. Purpose: To report a case of chickenpox mimicking monkeypox in an adult with diabetes mellitus and acute kidney injury. Case: A 51-year-old male with poorly controlled diabetes mellitus was suspected to have a chickenpox differential diagnosis with monkeypox. His chief complaint was multiple blisters on his body and vomiting. There was a history of feeding a monkey. From dermatological status on facial, trunk, and extremities there were multiple pleomorphic vesicles. Laboratory results showed elevated renal function. Polymerase chain reaction (PCR) examination using VZV as primer revealed a positive result in the range of 810 bp. He was treated with intravenous acyclovir for 3 days and oral acyclovir for 7 days then discharged with improvement in skin lesions and normal renal function. Discussion: Chickenpox in adult and diabetes mellitus patients can give severe clinical manifestation mimicking monkeypox. PCR has a significant role especially when diagnosis could not be established from the physical examination. Acyclovir can be given as the therapy. Conclusion: Adult and poorly controlled diabetes mellitus are important risk factors associated with the severity and complication of chickenpox. A careful diagnostic approach and management are needed.
Susbstance P Levels in Children with Atopic Dermatitis Khairina Nasution; Deryne Anggia Paramita; Nova Zairina Lubis
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 3 (2021): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.3.2021.182-186

Abstract

Background: Atopic dermatitis (AD) is the most common skin disease in infants and children. AD is influenced by hereditary and environmental factors, and it is characterized by an inflammatory reaction in the skin. In developing countries, children suffering from AD are estimated around 10–20%, of which 60% of the cases persist into adulthood. Substance P is a cutaneous neuropeptide that contributes to the pathogenesis of AD. Substance P promotes the production of nerve growth factors from keratinocytes, and the release of histamine, leukotriene, or tumor necrosis factor from mast cells, which cause the growth of sensory nerve fibers, augmentation of skin inflammation, and are considered pruritogenic factors. Purpose: This study aims to determine the description of substance P in children with atopic dermatitis using a descriptive observational study with a cross-sectional approach. Methods: This is a destructive observational study with a crossectional approach samples were selected from AD patients at the Universitas Sumatera Utara Hospital. Result: The largest group of subjects were childhood (2–12 years old), there was 60%, followed by the adolescent group (12–18 years old) and the infant group (<2 years old). In the childhood group, the highest level of substance P was found in girls with a mean of 349.03 ± 146.7. On the other hand, the highest levels of substance P in the adolescent were found in males with a mean of 243.73 ± 64.57 ng/L. Conclusion: In this study, we found that the level of substance p was higher in the childhood group.

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