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MEDISAINS
Published by Universitas Muhammadiyah Purwokerto
ISSN : 16937309     EISSN : 26212366     DOI : -
Core Subject : Health,
Medicine & Pharmacology Nursing Public Health
MEDISAINS: Jurnal Ilmiah Ilmu-ilmu kesehatan merupakan sarana penyebarluasan ilmu pengetahuan, riset, teknologi dan inovasi dibidang kesehatan yang diterbitkan tiga kali dalam setahun (April, Agustus dan Desember). Jurnal Medisains adalah jurnal peer reviewed dan Open-Access yang dikelola oleh Fakultas Ilmu Kesehatan Universitas Muhammadiyah Purwokerto dan di terbitkan dibawah Lembaga Publikasi Ilmiah dan Penerbitan (LPIP) Universitas Muhammadiyah Purwokerto.
Arjuna Subject : -
Articles 245 Documents
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Prediction of quality of life among the elderly based on level of depression and spirituality Salsabila, Nadia Nandina; Ariani, Tutu April; Aini, Nur; Marta, Ollyvia Freeska Dwi; Mashfufa, Erma Wahyu
MEDISAINS Vol 22, No 3 (2024)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v22i3.24272

Abstract

Introduction: Quality of life (QoL) in the elderly is shaped by physical, psychological, and spiritual factors. Depression commonly affects older adults and is linked to poorer QoL, while spirituality can offer resilience. However, the combined impact of depression and spirituality on elderly QoL is seldom explored.Purpose: This study aims to investigate the relationship between depression, spirituality, and QoL among elderly individuals in nursing homes, examining how these factors influence their physical, social, and mental well-being.Methods: This study used a cross-sectional study design conducted on nursing home residents. The study population was elderly living in nursing homes, with a sample size of 73 people selected by convenience sampling and calculated using G*power software. Quality of life (QoL) was measured using the SF-36 questionnaire, spirituality was measured using the Spiritual Well-Being Scale (SWBS), and depression was measured using the Beck Depression Inventory-II (BDI-II). Data analysis was performed using multiple logistic regression to analyze the relationship between the study variables.Results: Mean scores for physical and mental components of QoL were 50.06 (±6.80) and 50.22 (±8.73), respectively. Spirituality was positively associated with QoL, especially in social (AOR 1.15) and mental health (AOR 1.06) dimensions (p < 0.05). Depression was negatively related to vitality (AOR 1.11) and mental health (AOR 1.09), showing that greater spirituality aligns with higher QoL, while depression correlates with poorer QoL.Conclusion: Spiritual well-being and depression significantly impact elderly QoL, particularly in social, vitality, and mental health aspects.
Supplementation with sweet corn for weight gain in pregnant women Mudlikah, Siti; Nadhiroh, A`im Matun; Wiliyanarti, Pipit Festi
MEDISAINS Vol 22, No 3 (2024)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v22i3.24490

Abstract

Background: Inadequate nutrient intake during pregnancy can cause insufficient weight gain, chronic energy shortage, and difficulties for both the mother and the baby. This study highlights the benefits of sweet corn supplementation in improving weight gain and nutritional condition for pregnant women, addressing nutrient deficiencies and chronic energy shortages.Purpose: This study aims to determine the effect of sweet corn supplementation on increasing body weight in pregnant women.Method: The study employed a pre-experimental one-group pre-test-posttest design. Conducted in August 2024 at Posyandu in Jatikalang Village, it involved 18 pregnant women in their second and third trimesters who had not gained weight, with 15 selected purposively. Data analysis included a T-test statistical approach and the Subjective, Objective, Assessment, and Plan (SOAP) method for each participant.Results: The results showed that the average weight of pregnant women before the intervention was 63.87 kg; the average weight increased to 67.33 kg after the intervention (p<0.05). SOAP analysis found that after eating sweet corn, 67% of pregnant women obtained balanced nutrition, 60% gained weight, and the number of pregnant women with chronic energy deficit (CED) decreased from two to one (7%). In addition, 73% of pregnant women had a favorable opinion.Conclusion: The study suggests that sweet corn supplementation improves pregnant women's weight gain and overall nutritional condition.
Validity and reliability test of NIHSS-SDKI and CNS-SDKI in determining actual nursing diagnosis and severity of stroke patients Fitriana, Erlis Eka; Haryanto, Haryanto; Supriyadi, Supriyadi
MEDISAINS Vol 22, No 3 (2024)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v22i3.23111

Abstract

Background: The National Institutes of Health Stroke Scale (NIHSS) and The Canadian Neurological Stroke Scale (CNS) are two assessment tools often used for the assessment of neurological status in stroke patients. However, there are no assessment tools that use the standard nursing diagnoses developed in Indonesia, namely the Standar Diagnosis Keperawatan Indonesia (SDKI),  developed by the Indonesian National Nurses Association organization.Objective: This study aims to test the validity and reliability of the NIHSS and CNS combined with the SDKI so that they can be used to ensure the accuracy of the measuring instrument, determine its consistency, improve the quality of the assessment, and provide a basis for further research.Methods: This study is an observational study with a cross-sectional study design. The study was conducted at hospitals in Pontianak City, namely Tanjungpura University and Sultan Syarif Mohammad Alkadrie Hospital. The population in this study were all non-hemorrhagic stroke patients treated in the hospital, with a sample size of 30 patients. Sampling in this study was conducted using purposive sampling. Data collection began with the preparation of NIHSS and CNS instruments combined with SDKI, and then respondents' demographic data were collected. Data were analyzed using Pearson Correlation with SPSS statistical tools.Results: Based on the results of the validity and reliability tests, it was found that the NIHSS-SDKI and CNS-SDKI had a calculated r value> from the r table and Cronbach alpha value> 0.7 so that the NIHSS and CNS instruments were declared valid and reliable.Conclusion: Research on the NIHSS-SDKI and CNS-SDKI is valid and reliable, and it can be used as a tool to measure severity and help nurses make nursing diagnoses in accordance with the Indonesian Nursing Diagnosis Standards.
Development of medication reminder WhatsApp Bot application to improve medication adherence in pregnant women with hypertension Kurniasih, Hesti; Winarso, Septerina Purwandani; Sartika, Qona Lutfi
MEDISAINS Vol 22, No 3 (2024)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v0i0.23748

Abstract

 Background: Pregnant women's compliance with taking medication regularly is essential and supports the success of therapy. If pregnant women do not comply with taking medication, this can hurt the development of the disease and cause unexpected complications. Non-communicable diseases cause most cases of death in pregnant women. This is the basis for researchers to create a medication reminder system.Purpose: This research aims to develop a WhatsApp Bot application, WhatsApp Bot, that reminds users when to take medication. Method: This study employed Research and development, which consisted of four stages: Literature Study, Development Stage, Validity Expert, and Trial.Results: A system that health workers can use in primary health facilities to remind them when to take medication has been successfully created. Performance test of the medication reminder system with a high % accuracy rate of 98% (MAPE value 9.05%).Conclusion: This application is beneficial for pregnant women to remind them to take medication to increase compliance. 
Family center maternity care education for pregnant women through the approachin efforts to prevent stunting: a quasi-experimental Desiyanti, Irne Wida; Ardiningtyas, Lisa
MEDISAINS Vol 22, No 3 (2024)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v22i3.24035

Abstract

Background: Stunting in children is a health problem that has a great influence on their physical and mental development. In Indonesia, one of the causes of high stunting rates is the low health awareness of pregnant women, especially those who marry at a young age. Family factors have a significant influence on the success of stunting prevention, but family-based approaches are still rarely applied in pregnant women's health education programs.Purpose: This study aims to develop and evaluate the effectiveness of the Family Centered Maternity Care (FCMC)-based education approach in increasing knowledge and efforts to prevent stunting in pregnant women in Kolongan, North Minahasa.Methods: This study uses a quasi-experimental design with a pretest-posttest approach. The research sample consisted of 20 pregnant women who met the inclusion criteria. Data were collected through stunting knowledge questionnaires and stunting prevention efforts questionnaires, which were measured before and after FCMC interventions. Data analysis was carried out using the Wilcoxon test with a significance value of p<0.05.Results: The results of the study showed a significant increase in the level of knowledge and stunting prevention efforts among pregnant women after being given FCMC-based educational interventions. Before the intervention, only 25% of participants had high knowledge about stunting, but after that it increased to 75%. Stunting prevention efforts have also increased from 40% to 80%. The Wilcoxon test showed that this change was statistically significant (p = 0.033).Conclusion: The FCMC-based education approach has proven to be effective in increasing knowledge and efforts to prevent stunting in pregnant women. This education can be a reliable method in increasing awareness and preventive measures of pregnant women against the risk of stunting in their children.
Prevalence human papillomavirus type 6 and type 11 in pregnant women Haruna, Nadyah; Hatta, Mochammad; Hamid, Firdaus; Sultan, Andi Rofian; Safri, Safri; Farid, Monika Fitria; Lestari, Esa
MEDISAINS Early Release
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v0i0.23103

Abstract

Background: Pregnancy reduces the effectiveness of cell-mediated immunity, making the body more vulnerable to Human Papilloma Virus (HPV) infection. HPV comes in multiple variants, including non-pro-oncogenic varieties like 6 and 11. Less research has been done on low-risk HPV infections than on high-risk HPV since they are more frequently linked to genital warts and rarely result in cancer. Examples of these infections are types 6 and 11. It is necessary to conduct this study to ascertain whether asymptomatic pregnant women have been exposed to HPV types 6 and 11.Purpose: This study aims to determine prevalence HPV types 6 and 11 in pregnant women.Methods: A descriptive cross-sectional survey was carried out in Makassar in May 2023. The study Population consisted of pregnant women who underwent antenatal care at Tajuddin Chalid Hospital Makassar during the specified research period. After providing clarification and obtaining consent from eligible mothers, we collected a swab from the vaginal area. A PCR examination was conducted on the 167 maternal swabs that were received. Statistical analyses included frequency distribution using SPSS.Results: According to the study, 121 (72.5%) of the 167 samples tested positive for HPV type 6 DNA, while 46 (27.5%) tested negative. Meanwhile, 67% of 167 patients tested positive for HPV type 11 but were negative for the virus. Only 21 respondents with negative identification were found to be harboring both low-risk Human Papillomavirus types. In addition, 78 respondents received positive results for HPV types 6 and 11.Conclusion: Pregnant women can be infected with HPV types 6 and 11 even if they are asymptomatic. The high percentage of positive results suggests that routine maternal screening is recommended, especially during pregnancy.
Psychosocial therapy model to reduce anxiety levels in hemodialysis patients Ariyanto, Fajar; Pratiwi, Arum; Hudiyawati, Dian
MEDISAINS Vol 22, No 3 (2024)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v22i3.23788

Abstract

Background: Chronic kidney disease (CKD) is a global health issue that significantly impacts the quality of life of patients undergoing hemodialysis. Anxiety is one of the common psychological challenges faced by these patients. While various studies have addressed psychological and social interventions, most have focused on only one aspect, such as family support or psychological therapy, without considering the biological, social, and spiritual needs simultaneously. No research has integrated all these dimensions into a holistic approach.Purpose: This study aims to develop and evaluate a holistic nursing management model that combines all of these aspects to reduce anxiety levels for hemodialysis patients.Methods: This study used a mixed-method approach with an action research design. It was conducted at the Klaten Islamic Hospital. The population in the study was patients undergoing hemodialysis; as many as 15 patients participated in this study. The holistic nursing module was tested in five sessions, each lasting 15-30 minutes. Anxiety levels were measured using the Hamilton Rating Scale for Anxiety (HRS-A) before and after the intervention.Results: The study's results showed that the average level of anxiety in patients before the intervention was 35.13±3.22; after the intervention, it decreased to 24.87±1.68 (p<0.001).Conclusion: The application of the holistic nursing management model effectively reduced anxiety levels in hemodialysis patients.
Quality of life in gynecological cancer patients: focusing in religious aspects Mulyono, Wastu Adi; Ekowati, Wahyu; Ningrum, Fera Agusti; Nurhikmah, Salma; Maharani, Nadia Bella
MEDISAINS Vol 22, No 3 (2024)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v22i3.23781

Abstract

Background: Gynecological cancer is a malignancy that attacks the reproductive organs, affecting not only physical health but also psychological and emotional well-being, often causing depression and anxiety. Religious and spiritual factors have been identified as potential moderators of quality of life in cancer patients.Objective: This study evaluates the relationship between religious aspects spirituality, awareness, and religious coping and quality of life in gynecological cancer patients.Methods: A cross-sectional study involved 61 gynecological cancer patients undergoing chemotherapy at Margono Hospital. Data were collected using validated instruments: FACIT-Sp for spirituality, FMI for awareness, Brief R-Cope for religious coping, PSS-10 for stress, and WHOQOL-BREF for quality of life. The Pearson correlation coefficient was used to assess the relationship between variables.Results: Spirituality (r = 0.434), awareness (r = 0.425), positive religious coping (r = 0.313), and stress (r = -0.515) were significantly correlated with quality of life. Negative religious coping (r = -0.121) showed a negative but non-significant correlation.Conclusions: This study highlights that spirituality, mindfulness, and positive religious coping are significantly associated with improved quality of life in gynecologic cancer patients. These results emphasize the potential role of religious and spiritual support as an integral component of comprehensive cancer care to improve overall patient well-being.
Postural exercise impaction on the development of vertebral curves and functional deformity for adolescent idiopathic scoliosis Romadhoni, Dea Linia; Ramadhani, Alinda Nur
MEDISAINS Early Release
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v0i0.23017

Abstract

Background: Adolescent idiopathic scoliosis (AIS) is a common spinal deformity affecting children aged 10–18 years. Various treatment approaches, including specific exercises, bracing, surgery, traction, casting, and biofeedback, have been implemented to manage AIS. However, posture correction exercises remain a non-invasive rehabilitation strategy with the potential to prevent scoliosis progression and improve functional outcomes.Purpose: This study aimed to evaluate the effectiveness of posture correction exercises in reducing vertebral curvature deformity and improving functional abilities in adolescents with idiopathic scoliosis.Methods: This quasi-experimental study employed a one-group pretest-posttest design involving 30 students aged 10–15 years diagnosed with AIS. Participants underwent a four-week supervised posture correction exercise program. The primary outcome, vertebral curvature deformity, was assessed using the Adam’s Forward Bending Test, while changes in vertebral inclination angle were measured using a Scoliometer. All data were documented through structured questionnaires.Results: The findings revealed a statistically significant reduction in vertebral inclination angle following the intervention (p<0.001), indicating the effectiveness of posture correction exercises as part of scoliosis-specific rehabilitation programs.Conclusion: Posture correction exercises significantly reduce vertebral curvature deformity and enhance functional capabilities in adolescents with AIS. These findings support their integration into physiotherapy programs as a non-invasive rehabilitative and preventive approach for scoliosis management.
In vivo study of Centella asiatica leaf extract cream for Matrix Metalloproteinase-1 inhibition and collagen enhancement to prevent photoaging Purmawanti, Sri; W, Joko Wahyu; Sumarawati, Titiek
MEDISAINS Early Release
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v0i0.24719

Abstract

Background: Ultraviolet B (UVB) exposure accelerates skin aging, causing wrinkles and increasing matrix metalloproteinase-1 (MMP-1) activity, which degrades collagen. Centella asiatica (CA) has well-documented anti-inflammatory and antioxidant properties that may counteract UVB-induced photoaging. However, studies on its topical formulation for MMP-1 inhibition and collagen enhancement remain limited.Purpose: This study aims to determine the effect of CA leaf extract cream on inhibiting MMP-1 and increasing collagen in skin tissue exposed to UVB rays.Methods: This experimental study used a post-test only control group design. The sample population of BALB/c mice was 24, divided into four groups: healthy control group (KN), negative control group (K-), Treatment 1 (P1): 10% CA extract cream dosage, and Treatment 2 (P2): 20% CA extract cream dosage. Skin tissue samples were measured for MMP-1 expression using immunohistochemistry (IHC) staining, and collagen density using Sirius Red staining. Data analysis on MMP-1 expression using One-way ANOVA test and collagen density using Kruskal Wallis test.Results: MMP-1 expression was highest in the K2 group (UVB exposure + cream base) and decreased in the P1 and P2 groups (10% CA cream), with the lowest expression in the K1 group (healthy control). However, One-Way ANOVA showed no significant differences among groups (p=0.053). Collagen density analysis using the Kruskal-Wallis test showed significant differences (p = 0.04), with a decrease in the K2 group and an increase in the K3 and K4 groups.Conclusion: Application of CA extract cream affects MMP-1 expression and collagen density in skin tissue exposed to UVB rays.

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