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Jurnal Kedokteran
Published by Universitas Mataram
ISSN : 23015977     EISSN : 25277154     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
The Unram Medical Journal managed by the Medical Faculty of Mataram University is a scientific journal to publish the results of the latest research in the field of medical and health related. This journal promote medical sciences generated from basic sciences, clinical, and community research to integrate researches in all aspects of human health. This journal publishes original articles, reviews, and also case reports.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 408 Documents
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Gut-Brain Connection : The Role Of Gut Microbiome in Preventing Stroke Baiq Annisa Pratiwi; Putu Diah Ananda Putri Atmaja; Qurrata’yuni Pratiwi; Ilsa Hunaifi
Unram Medical Journal Vol 11 No 1 (2022): vol 11 no 1
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i1.536

Abstract

Stroke is the second most prevalent cause of death in the world and placed third in disability causes worldwide. Beside affecting health, the reduced quality of life and the expensive cost of its treatment also has a huge impact on social, physical, and psychological aspect of a patient. Currently, the management of stroke is centered on currative and rehabilitative effort. Hence, the preventive efforts are on demand. Several studies have showed that there is a link between gut microbiota and the nervous system in somehing called the Gut-Brain Axis (GBA). Intestinal microbiota plays an important role in GBA. Therefore, maintaining the balance of intestinal microbiota, through neuronal or non-neuronal two-way communication between both of those system, is a promising way to prevent stroke.
Faktor-Faktor yang Berhubungan dengan Jumlah Kelahiran Hidup pada Ib-Ibu di Wilayah Kerja Puskemas Masbagik, Lombok Timur Kartika Dewi; Yoga Pamungkas Sussani; Gede Wira Buanayuda
Unram Medical Journal Vol 11 No 1 (2022): vol 11 no 1
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i1.540

Abstract

Background: Fertility as a demographic’s term is defined as the real reproductive result of a woman or group of women. Fertility is influenced by several factors, where these factors play a role in the rate of population growth. Factors that influence fertility, consist of non-demographic factors and demographic factors. There is also an intermediate variable, factors that influence the start of sexual intercourse to the occurrence of pregnancy. Aim of this study is to evaluate correlations between mother’s age when giving first birth, age when giving recent birth, level of education, occupation and number of live birth on mother’s in the work area of ??Masbagik Primary Health Care Center Methods: This research is a quantitative study and uses a correlative research design with a cross-sectional approach on secondary data, taken from the medical records of patients who have given birth in the working area of ??the Masbagik Primary Health Care Center. Result: In this study, all factors studied had p<0.05 and it indicates that there is a meaningful relationship between the factors studied and the number of live births. Where educational factors as well as the age of mother first childbirth have a negative correlation relationship and the job factor and the age of the mother during childbirth has a positive correlation. Conclusion: There were significant correlation between factors that are studied with the total of live birth the mothers had on the work area of Masbagik Primary Health Care Center.
PENGARUH ELEUHTERINE PALMIFOLIA (L) MERR TERHADAP PROLIFERASI SEL TUMOR PADA TIKUS SPRAGUE DAWLEY DENGAN KANKER PAYUDARA Ratna Widayati; Yan Wisnu Prajoko; Udadi Sadhana
Unram Medical Journal Vol 10 No 4 (2021): Jurnal Kedokteran Volume 10 nomor 4 (Desember) 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i4.545

Abstract

Background : Immunotherapy is widely used to increase the response rate of chemotherapy drugs. Eleuhterine palmifolia (L) Merr or dayak onion are known to contain phytochemical compounds that have antiproliferative effects, and have been used as anti-cancer empirical therapies. This study aimed to prove the antiproliferative effect of Eleuhterine palmifolia (L) Merr extract in Sprague-Dawley rats with breast cancer. Methods : This study used 18 Sprague-dawley rats, divided into 3 groups, K, P1 and P2. K was given regular feed, P1 received adriamycin 5 mg/kgBW single dose, P2 received adriamycin 5 mg/kgBW single dose and extract of dayak onion 105 mg/kgBW/day for 3 weeks. Results : Difference in tumor size before and after treatment was 7.2 ± 2.57 mm (K), 3.23 ± 3.03 mm (P1), 3.14 ± 2.65 mm (P2), with p value is 0,157 (p>0,05). Ki-67 index calculations are 11.1 ± 7.27% (K), 9.64 ± 6.99% (P1), 9.58 ± 3.52% (P2), with p value is 0,704 (p>0,05). Conclusion : The addition of Eleuhterine palmifolia (L) Merr (dayak onion) extract did not cause a significant difference in tumor cell proliferation in Sprague-Dawley rats with breast cancer.
HUBUNGAN ANTARA ANGKA KECACINGAN DENGAN STATUS PENGUKURAN ANTROPOMETRI ANAK USIA SEKOLAH DASAR DI KECAMATAN PEMENANG KABUPATEN LOMBOK UTARA NUSA TENGGARA BARAT Gusti Anom Christyandi Ramarantika; Rifana Cholidah; Eva Triani
Unram Medical Journal Vol 11 No 1 (2022): vol 11 no 1
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i1.556

Abstract

Background: There are more than 1,5 billion cases of STH infections each year, with school-age children being the most susceptible demographic. Those infections could cause many health problems, some of which are nutrition related health problems. This study aims to learn about the correlation between helminth infection and anthropometry measurement of elementary school age children in Pemenang sub-district, North Lombok district, West Nusa Tenggara province. Method: This study uses correlation analysis with two categoric variables and consecutive sampling method. Helminth infections was checked trough feces sample examination. This study was carried out on SDN 1, S SDN 2, dan SDN 3 Malaka between May and December of 2019. Results: Helminth eggs was found on 23 samples (30,67%) from the total of 75 samples, with T.trichiura being the most frequent infections found (91,4%). Using Mann-Whitney test, it was found that there are no significant correlations between helminth infections and anthropometry measurement using height-for-age and weight-for-age indicators (p=0,814 & p=0,403), but there is a significant correlation between helminth infections and anthropometrical measurement using BMI-for-age indicators (p=0,025). Conclusion: There are no significant correlations between helminth infections and nutritional status that were assessed using height-for-age and weight-for-age indicators, but there is a significant correlation between helminth infections and nutritional status that was assessed using BMI-for-age indicator.
Kajian Literatur: Evaluasi Cara Distribusi Obat Yang Baik (CDOB) Pada Sarana Distribusi Obat Luthfanto Hafizhuddin; Ni Made Amelia Ratnata Dewi; Iman Surya Pratama
Unram Medical Journal Vol 10 No 4 (2021): Jurnal Kedokteran Volume 10 nomor 4 (Desember) 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i4.565

Abstract

There has been an increase in studies related to good distribution practices (GDP) in recent years. However, the literature review exploring GDP evaluation is limited. Therefore, this scoping review aims to map the current knowledge regarding the implementation of GDP in drug distribution facilities. A literature search was conducted in Google Scholar based on the modified PRISMA protocol. The literature that met the inclusion and exclusion criteria was then extracted into the table. The results of literature extraction show that the overall studies obtained are descriptive; studies are predominantly conducted on pharmaceutical wholesalers and Western Indonesia; regulations that used as references have not been updated; the results of the questionnaire have not been validated and using a small sample. Therefore, studies that can be carried out include looking at the factors that influence the implementation of GDP; explored the level of application of GDP in other distribution channels such as drugstores and Eastern Indonesia, and updated the study with new guidelines. As for validating the results of the questionnaire and using a larger sample of distribution facilities can be used as consideration for further research.
KARAKTERISTIK DAN UKURAN TONSIL PASIEN TONSILEKTOMI DI INSTALSI BEDAH SENTRAL RUMAH SAKIT UMUM PROVINSI NTB BULAN JULI TAHUN 2019 Eka Arie Yuliyani; Hamsu Kadriyan; Didit Yudhanto; Gusti Ayu Trisna A; Ayu Niti Wedayani Anak Agung; Lalu Muhammad Abiyu Ghafar; Fitriatulnisa
Unram Medical Journal Vol 11 No 1 (2022): vol 11 no 1
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i1.566

Abstract

Latar belakang: Tonsilitis kronis secara umum diartikan sebagai infeksi atau inflamasi pada tonsil palatina yang menetap. Pembesaran tonsil dapat menyebabkan beberapa komplikasi yang dapat menjadi indikasi dilakukanya operasi tonsilektomi. Tujuan dari penelitian ini adalah untuk mengetahui karakteristik dan ukuran tonsil pasien tonsikeltomi di Instalasi Bedah Sentral Rumah Sakit Umum Provinsi Nusa Tenggara Barat bulan Juli tahun 2019. Metode: Penelitian ini merupakan penelitian deskriptif retrospektif, dengan teknik consecutive sampling, menggunakan data sekunder pasien yang telah ada di RSUD Provinsi NTB bulan Juli 2019 kemudian di analisis dan disajikan dalam bentuk tabel dan narasi. Didapatkan 21 pasien yang menjalani tonsilektomi di IBS RSUP NTB selama bulan Juli 2019. Hasil: Distribusi berdasarkan tingkat umur nampak bahwa penderita tonsilektomi, sebagian besar adalah tergolong anak-anak yang berkisar pada umur 5-10 tahun. Berdasarkan jenis kelamin yang terbanyak adalah perempuan sebanyak 11 orang (52,4%).Penderita yang menjalani tonsilektomi lebih banyak karena indikasi relatif sebesar 19 pasien (90,5%) dengan keluhan utama terbanyak adalah nyeri pada tenggorok yaitu 12 orang (57,2%). Penderita tonsilitis kronis paling banyak mengalami pembesaran tonsil dengan ukuran tonsil T3-T3 yaitu 13 orang(61.9%). Kesimpulan: Dominasi indikasi melakukan tonsilektomi adalah indikasi relatif, yaitu keluhan yang berulang. Pasien yang menjalani operasi tonsilektomi paling banyak mengalami pembesaran ukuran tonsil T3/T3 dengan insiden tonsilektomi yang tinggi pada kelompok umur 5-10 tahun.
DIAGNOSIS DAN PENATALAKSANAAN OTOMYIASIS PADA OTITIS MEDIA SUPURATIF KRONIS Ayu Niti Wedayani Anak Agung; Eka Arie Yuliyani; Didit Yudhanto; Hamsu Kadriyan; Gusti Ayu Trisna A
Unram Medical Journal Vol 10 No 4 (2021): Jurnal Kedokteran Volume 10 nomor 4 (Desember) 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i4.567

Abstract

Otomyiasis merupakan infestasi larva pada telinga manusia yang disebabkan oleh lalatdari ordo diftera, subfamili Chrysomyinae. Infeksi larva pada telinga dapat mengenai telingabagian luar atau tengah, baik pada satu atau kedua telinga. Kami melaporkan satu kasusotomyiasis di RSUD Povinsi NTB pada penderita usia 30 tahun dengan otitis media supuratifkronis dan telah dilakukan ekstraksi larva, cuci telinga dengan larutan H2O2 3% dan NaCl 0,9%, serta pemberian antibiotik baik sistemik maupun topikal.
Metode Konsumsi dalam Pengelolaan Persediaan Obat, Alkes BHP dan APD di Laboratorium Kateterisasi RS selama Pandemi Sidhi Laksono
Unram Medical Journal Vol 10 No 4 (2021): Jurnal Kedokteran Volume 10 nomor 4 (Desember) 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i4.575

Abstract

COVID-19 merupakan masalah yang dihadapi tidak hanya di Indonesia tetapi juga seluruh dunia. Dengan meningkatnya angka infeksi COVID-19 di masyarakat akan mengubah pelayanan Rumah Sakit (RS), dimana akan menerapkan promosi kesehatan yang ketat di lingkungan RS. Selain itu, RS selama pandemi ini seharusnya bersiap dalam memenuhi ketersediaan obat dan alat kesehatan terutama alat pelindung diri (APD) yang akan dipakai oleh tenaga kesehatan. Semua bidang pelayanan di RS seharusnya bersiap menghadapi pandemi ini, tidak kecuali pada layanan kateterisasi jantung. Unit kateterisasi jantung pada awal pandemi tidak melakukan pelayanan untuk mencegah penyebaran Covid-19, akan tetapi selanjutnya dibuka pelayanan unit tersebut dengan beberapa persyaratan. Dengan dibukanya layanan pada unit kateterisasi jantung, dibutuhkan obat, alat kesehatan bahan habis pakai dan APD yang tepat selama pandemi ini. Manajemen logitik RS terutama instalasi farmasi RS (IFRS) berperan dalam pengelolaan dan penyediaan obat dan alat kesehatan yang dibutuhkan di RS. Diperlukan metode tertentu dalam pengelolaan tersebut, salah satunya dengan metode konsumsi. Makalah ini akan memberikan gambaran umum pengelolaan obat menggunakan metode konsumsi di laboratorium kateterisasi RS selama pandemi.
BEHCET DISEASE : MENGENALI VASKULITIS SISTEMIK LANGKA MULAI DARI AWITAN HINGGA TATALAKSANA Nofiana Ayu Risqiana Sari; Diajeng Aesya Mutiara Firdausy; Ima Arum Lestarini
Unram Medical Journal Vol 11 No 1 (2022): vol 11 no 1
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i1.581

Abstract

Behçet’s disease adalah kelainan langka dan menyebabkan vaskulitis sistemik dengan manifestasi klinis yang melibatkan multiorgan. Kelainan ini umumnya ditemukan pada negara-negara di sepanjang jalur sutra terutama negara di Timur Tengah. Turki merupakan salah satu negara dengan prevalensi yang tinggi. Penyebab penyakit ini belum diketahui secara pasti, namun kombinasi faktor genetik berupa keterlibatan gen HLA-B51 dan faktor lingkungan berupa infeksi virus herpes simpleks atau bakteri spesies Streptococcus turut berperan dalam mencetus penyakit ini. Manifestasi klinis multiorgan yang paling sering ditunjukkan pada penyakit ini meliputi ulserasi oral, ulkus genital, uveitis, tromboflebitis superfisial dan lain sebagainya. Diagnosis kasus dilakukan berdasarkan kriteria klinis dengan instrumen yang digunakan saat ini merujuk pada International Criteria for Behcet’s Disease . Tatalaksana yang diberikan pada penyakit ini bergantung pada manifestasi klinis yang muncul dengan tujuan terapi untuk meningkatkan kualitas hidup pasien. Beberapa komplikasi dari penyakit ini seperti kebutaan akibat uveitis yang tidak segera mendapat pengobatan bahkan kematian akibat aneurisma arteri pulmonalis. Prognosis yang buruk ditemukan pada pasien dengan manifestasi klinis tertentu.
Nephrolitiasis On Nephroptosis Patient I Made Ari Samudera; Akhada Maulana
Unram Medical Journal Vol 11 No 1 (2022): vol 11 no 1
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i1.583

Abstract

Nephroptosis or ren mobilis is defined as a descent in the anatomical position of the kidney by more than 2 corpus vertebrae (>5 cm). It is more common in women and on right kidney, although there were 10 % cases on left kidney and 20 % on bilateral kidney. Nephroptotic pain is a symptom that is often experienced by floating kidney patients. Complication of nephroptosis are hypertension and nephrolithiasis (kidney stones). Management of nephroptosis is nephropexy, or nephrectomy if there is kidney parenchymal damage. Reporting a 75-year-old female patient with right nephroptosis and kidney stone. She complained pain on the right lower abdomen that become better when patient lying. Patient has had hypertension too. On abdominal CT showed right kidney stone and severe hydronephosis. Position of the kidney was in the pelvic region. Patient then underwent right nephrectomy because parenchym of the kidney became very thin that damaged the kidney. Intra operative condition of this patient was stable, then patient discharged form hospital three days after surgery.

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