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Jurnal Kedokteran
Published by Universitas Mataram
ISSN : 23015977     EISSN : 25277154     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
The Unram Medical Journal managed by the Medical Faculty of Mataram University is a scientific journal to publish the results of the latest research in the field of medical and health related. This journal promote medical sciences generated from basic sciences, clinical, and community research to integrate researches in all aspects of human health. This journal publishes original articles, reviews, and also case reports.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 408 Documents
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POTENSI TERAPI GENETIK BERBASIS MESENCHYMAL BETA-STEM CELL SECARA AUTOLOGOUS PADA PENDERITA DIABETES MELITUS TIPE 1 Diajeng Aesya Mutiara Firdausy
Unram Medical Journal Vol 11 No 2 (2022): vol 11 no 2 2022
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i2.616

Abstract

Diabetes melitus merupakan penyakit metabolik kronik ditandai dengan kadar glukosa darah meningkat yang disebabkan oleh penurunan atau defisiensi insulin. Penyakit ini merupakan salah satu masalah kesehatan global yang menjadi perhatian dunia. Berbagai komplikasi serius yang disebabkan oleh diabetes termasuk penyakit pada jantung, mata, ginjal, pembuluh darah dan saraf. Gangguan peningkatan kadar gula darah pada diabetes melitus tipe 1 disebabkan kerusakan sel beta pankreas sehingga hormon insulin tidak dapat diproduksi. Salah satu pengembangan terapi yang dapat digunakan adalah terapi berbasis Mesenchymal Stem Cell secara autologous. Meskipun terdapat kelemahan pada terapi pengembangan ini, kelebihan yang didapatkan terbukti efektif dalam mengurangi bahkan tidak memerlukan insulin pada pasien diabetes mellitus tipe 1.
GAMBARAN EPIDEMIOLOGI FAKTOR RISIKO PREEKLAMSIA PADA IBU HAMIL ika primayanti; Ario Danianto; Rizkinov Jumsa; NN Geriputri; Marie Yuni Andari
Unram Medical Journal Vol 11 No 1 (2022): vol 11 no 1
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i1.624

Abstract

Preeclampsia is one of the main causes of maternal death in addition to bleeding and infection. The increasing incidence of preeclampsia is of course a problem amid increasing efforts to provide maternal health services. Risk factors for the incidence of preeclampsia can be found through history assessment and special examinations at antenatal care. Through early detection of risk factors for preeclampsia, it is hoped that maternal and perinatal morbidity and mortality can be prevented. This study aims to identify in order to obtain an epidemiological description of the risk factors for the incidence of preeclampsia in pregnant women. The research design was descriptive observational with cross sectional approach. The research data were obtained from interviews, KIA’s book, accompanied by blood pressure checks and proteinuria examinations through a simple dip test of second trimester pregnant women who underwent antenatal care in July - November 2021 About 52 sample have been taken by purposive sampling technique. Obtained 8 of 9 moderate risk factors for preeclampsia in respondents with the most factor being Mean Arterial Pressure (MAP) >90mmHg about 17 respondents (32.7%) while in high risk factors for preeclampsia where the most factor is a history of chronic hypertension namely 2 respondents (3.8%).
Skabies dengan Infeksi Sekunder Pada Sindrom Down Mitha Yunda Pertiwi; Dedianto Hidajat
Unram Medical Journal Vol 10 No 4 (2021): Jurnal Kedokteran Volume 10 nomor 4 (Desember) 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i4.625

Abstract

Scabies is a skin disease caused by Sarcoptes scabiei. The signs and symptoms of scabies such as pruritus and skin lesions in the form of small papules with canaliculus and escoriations. If it’s not treated, complications may occur. The most common complication is secondary infection. The principles in the management of scabies are eradicating mites with pharmacological therapy, preventing the spread of scabies, and overcoming complications. A 1-year-7-month-old child with down syndrome was consulted to the dermatovenereology clinic of RSUDP NTB with complaints of lesion since 1 month ago in the buttocks, genital, between the toes and soles, between the fingers and palms, and around the chest. The patient scratches the spots at night. The patient’s father, mother and brother experiencing similar complaints. Localized status of skin lesions are on the buttocks, external genitalia, thorax, between the fingers and toes, as well as the palms of the hands and feet. The description of lesions were papules with grayish white canaliculus, well-defined, lenticular shape, multiple, discrete arrangement, and regional distribution with scales. In addition, there are white pustules, well-defined, miliary shape, multiple, discrete arrangement, and regional distribution with crusts. The diagnosis of this patient was clinical scabies with secondary infection. The patient was given causative, symptomatic and secondary infection therapy. In addition, to treat patients, the family approach has an important role in eradicating scabies.
PIROXICAM YANG DIDUGA SEBAGAI AGEN PENYEBAB STEVEN-JOHNSON SYNDROME : SEBUAH LAPORAN KASUS Rifqie Courie; Dedianto Hidajat
Unram Medical Journal Vol 10 No 4 (2021): Jurnal Kedokteran Volume 10 nomor 4 (Desember) 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i4.627

Abstract

Steven-Johnson Syndrome (SJS) is an acute mucocutaneous reaction characterized by extensive necrosis and exfoliation of the epidermal layer. The most common etiology or trigger in SJS cases is drugs or their metabolites, followed by infection and idiopathic. The most common drugs that trigger SJS include sulfonamides, non-steroidal anti-inflammatory drugs (NSAIDs) such as oxicam derivatives, imidazole antifungals, cephalosporins, anticonvulsants, allopurinol, broad-spectrum bactericidal agents, and the regimen. Highly Active Anti Retroviral Therapy (HAART). A 42-year- old woman with complaints of blisters on the lips and eyelids and red spots on the body, hands and feet. These complaints began to arise after the patient took the drug Piroxicam. The lesions on the forehead, eyelids, lips and neck in the form of erythematous macular-patch lesions, irregular in shape, poorly demarcated, with lenticular-plaque size, discrete-confulnous arrangement, regional distribution accompanied by erosions and hemorrhagic crusts. lesions on the abdomen, hands and feet in the form of macules – erythematous patches with purpura in the central part, round andin shape irregular, with miliary-plaque size, with discrete-confluent arrangement and generalized distribution with blackish brown erosions and crusts on the left upper quadrants of the abdomen, erosions and hemorrhagic crusts on the left upper arm. The patient was diagnosed with Steven- Johnson Syndrome who later died from aspiration on day 9. The presence of precipitating factors and skin and mucosal lesions that lead to SJS can speed up clinical decision making so that treatment is given more quickly.
Hubungan Lama Menjalani Hemodialisis dengan Status Gizi Pada Pasien Penyakit Ginjal Tahap Akhir yang Menjalani Hemdialisis di RSUD Provinsi NTB Komang Adi Praja Semara Putra; I Gede Yasa Asmara; Rifana Cholidah
Unram Medical Journal Vol 10 No 4 (2021): Jurnal Kedokteran Volume 10 nomor 4 (Desember) 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i4.633

Abstract

Background: Chronic kidney disease is characterized by a decrease in kidney function for at least three months or more, a decrease in kidney function seen from a decrease in GFR < 60 ml/minute/1.73m2. The end stage of chronic kidney disease is known as end stage renal disease. Patients with end-stage renal disease require therapy to replace kidney function, one of the therapies that can be used is hemodialysis. Malnutrition is a condition that is often found in end-stage renal disease patients undergoing hemodialysis. Methods: This research is an observational analytic with a cross-sectional approach. Data were obtained from direct measurements and medical records of end stage kidney disease patients undergoing hemodialysis at the NTB Provincial Hospital with consecutive sampling technique. The analysis was carried out using the SPSS application. Results: In this study, there were 116 data that met the inclusion and exclusion criteria. Based on BMI, 13 of 116 samples were malnourished, 58 of 116 had normal BMI and 45 of 116 were overweight. Based on serum albumin, 33 of 116 had hypoalbuminemia and 83 of 116 had normal serum albumin. Conclusion: There was no relationship between duration of hemodialysis and body mass index of end-stage renal disease patients undergoing hemodialysis (p=1,000). There was a relationship between duration of hemodialysis and serum albumin in end-stage renal disease patients undergoing hemodialysis (p<0.00
UJI AKTIVITAS ANTI KOLONISASI BAKTERI ASAM LAKTAT DARI KEFIR SUSU KAMBING TERHADAP BAKTERI Escherichia coli PENGHASIL Extended Spectrum Beta Lactamase PADA USUS MENCIT BALB/c Qurrata'yuni Pratiwi; Eustachius Hagni Wardoyo; Eva Triani
Unram Medical Journal Vol 10 No 4 (2021): Jurnal Kedokteran Volume 10 nomor 4 (Desember) 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i4.634

Abstract

Escherichia coli (E.coli) is a type of Gram negative bacteria species which is a normal flora in the digestive tract. However, it can potentially become pathogenic if the number in the digestive tract increases. E.coli infection can cause various inflammatory bowel diseases, such as IBD, Crohn's and ulcerative colitis (Khan et al., 2018). Several studies have found that probiotics can act as preventive and therapeutic agents to eradicate pathogenic bacteria through inhibition of adhesion and colonization. This study is conducted to determine the potential of BALB in inhibiting the colonization of ESBL-producing E.coli in vivo in BALB/c house mouse. The results of the in vivo colonization test show that BALB has good colonization inhibitory activity against ESBL-producing E.coli which is indicated by a decrease in the number of ESBL-producing E.coli colonies in pellet-induced BALB/c house mouse and CFS BAL.
Hipertensi Sebagai Determinan Utama untuk Peningkatan Risiko Stroke pada Populasi Penduduk di Daerah Pesisir Herpan Syafii Harahap; Ilsa Hunaifi; Ghalvan sahidu; Stephanie Elizabeth Gunawan; Setyawati Asih Putri; Ni Nyoman Ayu Susilawati; Baiq Hilya Kholida
Unram Medical Journal Vol 11 No 1 (2022): vol 11 no 1
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i1.641

Abstract

Hypertension is the main determinant of stroke in the population in coastal areas. This is mainly related to the pattern of daily high sodium salt intake that is characteristic for the population in these areas. Chronic consumption of sodium salt > 5 grams/day will increase the risk of hypertension. Since marine fish naturally have high levels of sodium and its level will be increased during processing and packaging, chronic consumption of marine fish can be considered as a risk factor for hypertension and stroke as well. Pathophysiologically, high sodium levels for a long period may cause dysfunctional of pressure natriuresis, a condition that underlies hypertension. The hypertension itself will then induce the structural changes of blood vessels wall in the brain that support the occurrence of stroke. Since economically, the use of sodium salt for the preservation process, taste modification, and color and texture modification of seafood products, including marine fish, is more affordable, while the availability of substitutes for sodium salt for these purposes is relatively expensive and not always available, educational program for coastal communities related to daily sodium salt consumption control as an effort to prevent stroke are a distinct challenge for local health authorities.
Penggunaan Penggunaan Kanula Hidung Arus Tinggi (KHAT) Untuk Proses Penyapihan Ventilasi Mekanis pada Pasien Penyakit Paru Kronik (Laporan Kasus) Prasenohadi; Muhamad Iman Nugraha; Aisyah Ayu Syafitri
Unram Medical Journal Vol 11 No 1 (2022): vol 11 no 1
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v11i1.643

Abstract

Ventilasi mekanis adalah suatu alat bantu pernapasan yang digunakan untuk memberikan oksigen dengan tekanan positif. Ventilasi mekanis diindikasikan pada pasien dengan gagal napas akut berat ataupun pada pasien yang mengalami Acute Respiratory Distress Syndrome (ARDS). Penggunaan ventilasi mekanis jangka panjang merupakan salah satu faktor yang dapat menyebabkan tingginya angka mortalitas dan morbiditas pada pasien yang di rawat di Respiratory Intensive Care Unit (RICU). Penyapihan ventilasi mekanis merupakan tujuan akhir penggunaan ventilasi mekanis. Proses penyapihan dengan menggunakan kanul hidung arus tinggi dapat mengurangi risiko terjadinya kejadian kegagalan penyapihan dan mengurangi risiko terjadinya reintubasi pasien. Kami melaporkan kasus seseorang dengan diagnosis sindrom obstruksi pasca infeksi tuberkulosis dan penyakit paru obstruktif kronik dengan gagal napas hiperkapnia disertai dengan penurunan kesadaran akibat keracunan CO2 dan digunakan ventilasi mekanis sebagai tatalaksana. Kanula hidung arus tinggi digunakan pada pasien sebagai bagian dari proses penyapihan ventilasi mekanis. Penggunan kanula hidung arus tinggi (KHAT) diperuntukkan untuk mempercepat proses penyapihan dan mengurangi risiko terjadinya reintubasi pada pasien.
Tingkat Pengetahuan dan Sikap tentang Metode Penatalaksanaan Jenazah Pasien COVID-19 pada Mahasiswa Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Mataram Ida Lestari Harahap; Arfi Syamsun; Lenny Herlina
Unram Medical Journal Vol 10 No 4 (2021): Jurnal Kedokteran Volume 10 nomor 4 (Desember) 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i4.644

Abstract

Latar belakang: Corona virus of Disease (COVID-19) merupakan penyakit respirasi akut yang disebabkan oleh COVID-19 yang menyerang orgam paru-paru.. Masyarakat menganggap bahwa jenazah pasien covid dapat menyebarkan virus. Namun sebenarnya penanganan yang baik oleh tenaga medis pada jenazah pasien COVID-19 tidak akan memberikan penularan. Hal ini yang perlu dipahamkan kepada masyarakat. Di sini peran mahasiswa kedokteran sangat penting untuk dapat menyampaikan hal yang benar. Metode : Penelitian dilakukan menggunakan total sampling. Instrumen penelitian berupa kuisioner yang terdiri dari 4 aspek pengetahuan dan 1 aspek sikap. Aspek pengetahuan yang ingin digali adalah pengetahuan tentang informed consent terkait penatalaksanaan jenaah covid-19 Hasil dan kesimpulan : Secara umum pengetahuan dan sikap mahasiswa kedokteran terhadap penatalaksanaan jenazah pasien COVID-19 pada kategori cukup dan baik dengan rata-rata 81,6% untuk pengetahuan dan 46,5 % untuk sikap.
Kualitas Hidup pada Pasien Pasca Serangan Jantung di RSU Kota Mataram Tahun 2019-2020 seto priyambodo; Basuki Rahmat; I Putu Arya Primananda; Kadek Adi Sagita Reka Baya
Unram Medical Journal Vol 10 No 4 (2021): Jurnal Kedokteran Volume 10 nomor 4 (Desember) 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i4.645

Abstract

Background: Acute coronary syndrome is a non-communicable disease whose prevalence is increasing every year. The impact after a heart attack is a decrease in the patient's quality of life. This study aims to determine the characteristics and factors associated with the quality of life of patients after a heart attack. Methods: This research is a quantitative study with a cross sectional design. The research sample was patients after a heart attack at the Mataram General Hospital in 2019-2020. Data on smoking characteristics and status were collected through forms using a structured questionnaire, while quality of life data was collected using the SF-36 questionnaire. Results: Characteristics of post-heart attack patients at Mataram General Hospital were male (86.7%), aged <60 years (60%), smoking status (40%), STEMI diagnosis (50%), and poor quality of life. (63.6%). No significant relationship was found between gender , age , type of diagnosis and smoking status with the patient 's quality of life . Conclusion: There are 63.6% of patients with poor quality of life. There is no significant relationship between gender, smoking status, age, type of diagnosis and quality of life. Patients with smoking status tend to have a poor quality of life in the domains of physical roles (91.7%) and emotional roles (83.3%).

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