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Dental Journal (Majalah Kedokteran Gigi)
Published by Universitas Airlangga
ISSN : 19783728     EISSN : 24429740     DOI : -
Core Subject : Health,
Dentistry
The Dental Journal (Majalah Kedokteran Gigi) (e-ISSN:2442-9740; p-ISSN:1978-3728) is published by the Faculty of Dental Medicine, Universitas Airlangga. Its diciplinary focus is dental science and dental hygiene. The Dental Journal (Majalah Kedokteran Gigi) is published in English on a quarterly basis with each 50-60 page edition containing between nine and eleven scientific articles on research, study literature and case studies. Contributors to the Dental Journal (Majalah Kedokteran Gigi) included: dental researchers, dental practitioners, lecturers, and students drawn from Indonesia and a wide range of other countries.
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Articles 15 Documents
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Search results for , issue "Vol. 58 No. 4 (2025): December" : 15 Documents clear
Effect of tooth graft particle size on the healing process of femur defects in Wistar rat (Rattus norvegicus) Fauzia, Malianawati; Kumala, Ega Lucida Chandra; Brilliando, Okky Satria; Ayu, Devi Amelia; Napitu, Theresia Agata Winnitya
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 4 (2025): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i4.p388-394

Abstract

Background: Teeth have potential as bone graft materials because of their organic and inorganic components that can stimulate osteoinduction, osteoconduction, and osteogenesis. An important success indicator of treatment using this graft material is the formation of osteoblast and new blood vessels in the applied area. Purpose: To investigate the number of osteoblast, osteoclast, and new blood vessels in bone healing after the implantation of tooth-derived bone graft materials measuring 20, 40, and 60 mesh. Methods: Thirty-six Wistar rats with a 2 mm defect on the right femoral dextra condile were divided into four groups. P0 (n=9) was the control group, where the defect was not filled by any material. In the other groups, the defects were filled by 20-mesh (P1; n=9), 40-mesh (P2; n=9), and 60-mesh (P3; n=9) tooth graft material. The Wistar rats were sacrificed after 2 weeks, and then the preparations were hematoxylin eosin staining. The data were analyzed using one-way analysis of variance and Tukey’s post hoc test. Results: The highest number of osteoblast was in the P3 group with a mean of 49.67, highest number of new blood vessels in the P2 group with a mean of 39.89, and highest number of osteoclast in the P1 group with a mean of 20.44. Statistical analysis showed a significant difference in the number of new blood vessels, osteoclast, and osteoblast in each group (p=0.000; p<0.05). Conclusion: Particle size differences in tooth graft material affect osteogenesis and angiogenesis in the bone healing process.
Salivary glucose levels and estimation of food intake in type 2 diabetes mellitus patients Tjahajawati, Sri; Chandra, Angievel; Rafisa, Anggun
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 4 (2025): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i4.p336-341

Abstract

Background: Saliva, an easily collectible organic fluid, offers a noninvasive means for multiple samplings to determine salivary glucose levels, comparable to blood and potentially helpful in diagnosing and monitoring type 2 diabetes mellitus. Purpose: This research was carried out to determine the value of salivary glucose levels and food intake in patients with type 2 diabetes mellitus. Methods: This research utilized a descriptive quantitative method with a cross-sectional approach. The study population comprised type 2 diabetes mellitus patients in Bandung and Jatinangor. The samples, consisting of 27 individuals from each group—type 2 diabetes mellitus patients and healthy participants—were collected through purposive sampling. Saliva was collected using the spitting method and measured to determine salivary glucose levels (mg/dL). Food intake per day (in grams) was assessed using a semi-quantitative food frequency questionnaire and converted using NutriSurvey 2007. Results: Among the 27 participants with type 2 diabetes mellitus, salivary glucose levels were found to be ≥2 mg/dL (mean 23.47 mg/dL), whereas in the healthy group, 5 participants (18.5%) exhibited salivary glucose levels <2 mg/dL (mean 8.29 mg/dL). Most type 2 diabetes mellitus patients and healthy participants reported food intake below the Indonesian dietary recommendations. Conclusion: In our limited sample, salivary glucose levels in type 2 diabetes mellitus patients were higher compared to healthy participants. Energy intake in both groups showed similar results. Salivary glucose levels and BMI exhibited a correlation, though notably weak in this study.
Early intervention of anterior crossbite and unfavorable tongue posture with a prefabricated myofunctional appliance: A case report Asturini, Putri Ganesha; Wahono, Nieka Adhara
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 4 (2025): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i4.p415-420

Abstract

Background: Anterior crossbite in the primary dentition may be an early indicator of a developing Class III malocclusion. Clinical findings, hereditary factors, and environmental influences, such as breathing problems and tongue posture, should be considered for early intervention. Purpose: This case report describes the early diagnosis and intervention of anterior crossbite and unfavorable tongue posture as potential risk factors contributing to a Class III growth pattern. Case: An 8-year-old girl with a history of preterm birth and a familial history of Class III malocclusion presented with the chief complaint: lower teeth in front of upper teeth. Clinical findings included anterior crossbite in the primary canines, mild lower incisor crowding, and mesiocclusion in both second primary molars. The cephalogram revealed bimaxillary retrusion (SNA = 79°, SNB = 74°), a skeletal Class I (ANB = 4°, Wits = –2 mm), and a forward tongue posture. Case Management: An ENT specialist diagnosed the patient with allergic rhinitis, without any airway obstruction. A prefabricated myofunctional appliance was prescribed to guide the eruption of permanent teeth into their ideal positions, eliminate maxillary growth restriction, and retrain tongue posture. The anterior crossbite of the primary teeth and the crowding were corrected within 9 months. Use of the appliance is ongoing until all permanent incisors have fully erupted and ideal occlusion is achieved. Conclusion: Myofunctional therapy during early mixed dentition may serve as a beneficial interceptive treatment to retrain orofacial muscles and guide the eruption of permanent teeth into an ideal occlusion.
Effect of freeze-dried platelet-rich plasma on FGF-2 and type I collagen expression in traumatic ulcers of diabetes mellitus: An in vivo study Riskayanti, Ni Putu; Radithia, Desiana; Maharani, Annissaqiella; Hendarti, Hening Tuti; Rahayu, Retno Pudji; Surboyo, Meircurius Dwi Condro; Ernawati, Diah Savitri
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 4 (2025): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i4.p361-366

Abstract

Background: Diabetes mellitus is a chronic disease characterized by the pancreas’s inadequate production of insulin or the body’s impaired utilization of insulin, resulting in dysregulation of blood sugar levels. Diabetes mellitus causes prolonged wound healing due to decreased growth factors, including fibroblast growth factor 2 (FGF-2) and type I collagen. Purpose: This research analyzes the effect of topical administration of freeze-dried platelet-rich plasma (FD-PRP) on the healing process of traumatic ulcers in diabetic Wistar rats by increasing FGF-2 and type I collagen expression. Methods: Allogenic FD-PRP was obtained from the blood of 35 Wistar rats and 2% carboxymethyl cellulose (CMC) was added to make a gel formulation. Diabetes was induced in 30 Wistar rats using streptozotocin, followed by the creation of traumatic ulcers on the lower labial mucosa using a hot burnisher. The traumatic ulcers were then topically treated with FD-PRP gel in the treatment group and 2% CMC gel in the control group. Analysis of FGF-2 and type I collagen expression was performed through indirect immunohistochemical methods following treatment for 3, 5, and 7 days. Results: The expression of FGF-2 and type I collagen in the FD-PRP was higher than in the control group (p < 0.05). Conclusion: Topical application of FD-PRP plays an important role, especially in increasing the FGF-2 and type 1 collagen expression, in the healing process of traumatic ulcers in diabetic Wistar rats.
Difference of mandibular trabecular bone fractal dimension values on panoramic radiographs of vegetarians and nonvegetarians in Medan City Kartika, Dewi; Manja, Cek Dara; Wulandari, Pitu; Salamatusshodri; Sidabutar, Herlina
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 4 (2025): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i4.p347-354

Abstract

Background: Vegetarians are known to be more susceptible to experiencing bone mineral density decreases compared to nonvegetarians. The trabecular bone is sensitive to any changes that disrupt the balance of bone metabolism. On panoramic radiographs, bone density can be evaluated by analyzing the fractal dimensions (FD) of the mandibular trabecular bone. Purpose: This analytical cross-sectional study aimed to assess the mandibular trabecular bone FD values on panoramic radiographs of vegetarians and nonvegetarians in Medan City. Methods: This study used a purposive-sampling technique and obtained 30 digital panoramic radiographs of vegetarians and nonvegetarians in Medan City, aged 20 to 40 years, between January and February 2023, at the radiology installation of Dental and Oral Hospital Universitas Sumatera Utara and Laboratory Clinic Pramita Medan. Fractal analysis was performed using ImageJ 1.54c software with the box-counting method. The data distribution was assessed using the Shapiro–Wilk test. The data were analyzed using an independent samples T-test. Results: The results showed that the FD values of the mandibular trabecular bone were significantly different between the two groups (p = 0.000). Conclusion: The mean FD values on the panoramic radiographs were lower in the vegetarian mandibular trabecular bone than in the nonvegetarian mandibular trabecular bone. Considerations need to be made by dentists when performing treatments related to mandibular trabecular bone surgery in vegetarians.
Linear and three-dimensional volumetric analysis of maxillary sinus in Saudi Arabian population: A cone-beam computed tomography study Singhai, Anuroop; Gharote, Harshkant; AlAbrash, Mohamad Abdulhamid; AlRajhi, Raghad Saad; Abdullah, Ranya Qasem; AlWatban, Haya Ahmed
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 4 (2025): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i4.p325-329

Abstract

Background: The maxillary sinus presents as an important anatomical structure and understanding its radiographic anatomy is crucial for surgical procedures such as dental implant placement and extractions. Measuring the linear and volumetric dimensions of the maxillary sinus is essential for accurate treatment planning and a favorable outcome. Forensic odontology requires population-specific data for victim identification. There is therefore some need to develop a multicentric, multiethnic data registry. Purpose: The present study evaluates and compares the dimensions of maxillary sinuses and their relationship with individual height in the Saudi Arabian population, using cone-beam computed tomography (CBCT). Methods: The study subjected CBCT scans of 30 individuals to linear and volumetric analysis. The measurements were taken by two observers and mean dimensions were used for the analysis. Linear and volumetric dimensions were measured for the total sample and male (n=11) and female (n=19) categories. Results: Differences between linear and volumetric dimensions were statistically nonsignificant for males, females, and the overall sample. Correlations between left- and right-sinus dimensions were significant within females and the overall group. There was weak association between individual height and maxillary sinus dimensions. Conclusion: There is no significant variation between right and left maxillary sinus dimensions among the Saudi Arabian population. A negative correlation was observed between overall height and left maxillary sinus volume in both genders, and with right sinus volume in females only.
Confirmation of the potential mechanism of pentagamavunon-0 against temporomandibular arthritis using bioinformatic approaches Robin, Dwi Merry Christmarini; Ardhani, Retno; Novitasari, Dhania; Kusumawardani, Banun; Aulia Rahman, Faaza; Meiyanto, Edy; Purwanti, Nunuk
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 4 (2025): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i4.p367-375

Abstract

Background: Non-steroidal anti-inflammatory drugs (NSAID) are widely used in temporomandibular joint osteoarthritis management. However, the side effects of NSAIDs on multiple organs need to be anticipated. Curcumin is known for its anti-inflammatory and analgesic potential, comparable to that of NSAIDs. In a previous study, structurally modified curcumin increased the pharmacological effect and simultaneously reduced the toxicity and side effects of curcumin. Pentagamavunon-0 (PGV-0) is one of the active components synthesized by the structure modification of curcumin. Purpose: In this study, we identify the potential target of PGV-0 on the pathogenesis of temporomandibular arthritis characterized by inflammation. Methods: We used a bioinformatics approach to compare the PGV-0 target with curcumin and diclofenac sodium as controls. We identified overlapping gene targets of bioactive compounds (PGV-0, curcumin, or diclofenac sodium) retrieved from the SwissTargetPrediction and GeneCards platforms, specifically for temporomandibular arthritis. An interaction model among targets was developed using the STRING database and Gene Ontology Panther to expound on the bioactive compound’s function on the key signaling pathway. Finally, we formulated a molecular docking prediction between the bioactive compound and the target protein marker derived from the previous analysis using Molecular Operating Environment tools. Results: This study found that curcumin and PGV-0 targeted different molecular pathways in temporomandibular arthritis compared to diclofenac sodium. Curcumin and PGV-0 shared a similar pathway to curcumin by modulating metalloproteinases (MMPs), especially MMP-9 and MMP-13. Moreover, diclofenac sodium influenced cyclooxygenase metabolism. Conclusion: In this study, PGV-0 targeted metalloproteinase in temporomandibular arthritis pathogenesis. This finding underlines the PGV-0 advantage in preventing metalloproteinase-related tissue damage in temporomandibular arthritis.
The role of forensic odontology in the identification of a mutilation victim: A case report Yatma, Debby; Auerkari, Elza Ibrahim; Yuniastuti, Mindya; Soedarsono, Nurtami; Suhartono, Antonius Winoto; Kaurow, Farah P.; Pasaribu, Roben Suhadi; Auerkari, Pertti
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 4 (2025): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i4.p409-414

Abstract

Background: Forensic odontology is an invaluable resource for human identification. An individual’s bones and teeth may be the only remnants of their identity in certain situations where soft tissue has been lost, carbonized, or destroyed for any other reason. The body’s hardest and best-protected structures are found in teeth, and these have individual characteristics and are resistant to factors such as temperature and chemistry. When antemortem dental records are not available for comparison, dental profiling is performed. Purpose: This case study highlights the importance of teeth in the identification process and their usefulness in estimating biological profile factors such as sex, age, and population affinity. Case: The case of an unidentified woman who was found in a house in a severely decomposed, skeletonized state is presented. The unidentified body was sent to the Forensic Medicine Installation of Bhayangkara Level I Hospital to determine the cause of death and for dental identification. Case management: The body was suspected to be a victim of mutilation. Shovel shapes observed on the lingual surface of the lateral upper incisor and tori palatini are the most outstanding diagnostic features in Mongoloid populations. The specific mesiodistal crown width and mandibular canine index revealed female traits. Using the Lamendin method, the age was estimated to be 52–58 years old. Conclusion: A forensic odontologist can identify individuals by comparing antemortem and postmortem dental data. They can also provide age estimation, sex, and population affinity determination by analyzing teeth.
A comparative clinical study of two different attachment systems and implant stability in implant-supported mandibular overdentures Belal, Ammar Omar; Elmahdy, Moataz Mostafa Bahgat; El Masry, Sayed Mohammed Mohammed; Elsayed, Mohamed Ezzat
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 4 (2025): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i4.p330-335

Abstract

Background: Implant stability is crucial for the long-term durability of implant-supported removable dentures. Understanding the clinical impact of attachment systems such as Novaloc and Locator on stability is essential for their potential prognosis. Purpose: The aim of this study is to compare the effects of Novaloc and Locator attachment systems on implant stability in implant-supported overdentures. Methods: The research sample consisted of 10 patients, all entirely edentulous in the lower and upper jaws. Each patient received a conventional complete denture in addition to two implants in the mandible. Equal numbers of patients were assigned to Group 1: Novaloc attachment system and Group 2: attachment system for locators. Implant stability was evaluated using the MegaGen implant stability quotient device and repeated after 4, 8, and 12 months. The SPSS program was used to collect, calculate, and statistically analyze the data. Results: According to one-way ANOVAs and independent t-tests conducted throughout the observation period, both groups demonstrated an improvement in implant stability, but the Novaloc group showed superiority, with statistically significant differences (P > 0.05). Conclusion: Based on the study’s findings, in comparison to the Locator system, the Novaloc attachment system offers better implant stability during a 1-year monitoring period.
Potential of Bombyx mori fibroin peptide as an inhibitor of BMP2 and TGFB1 in the treatment of pulp tissue damage Puspita, Sartika; Makiyah, Sri Nabawiyati Nurul; Kita, Masaki; Ahkam, Ahmad Hafidul
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 4 (2025): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i4.p395-401

Abstract

Background: Silk from Bombyx mori, a species of silkworm, contains fibroin, which has good biocompatibility and is potentially suitable for medical applications, especially in the treatment of tissue damage. Purpose: This study evaluated the potential interaction of B. mori fibroin peptides with bone morphogenetic protein 2 (BMP2) and transforming growth factor beta 1 (TGFB1), which are protein markers for dentine reparative activity. Methods: The research was carried out in silico. The three-dimensional structure of the proteins was obtained from the Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), and the antimicrobial potential of fibroin was evaluated using Antimicrobial Peptide Scanner v.1, the Collection of Anti-Microbial Peptides (CAMPR3), PeptideRanker, ToxinPred, AlgPred, and AllergenFP. Molecular modeling and analysis were performed with trRosetta, PrankWeb, the HDOCK server, and Discovery Studio. Results: The light chain 1 peptide (LC1), light chain 2 peptide (LC2), heavy chain 2 (HC2), and heavy chain 7 (HC7) showed high binding affinity to BMP2, while LC2, HC1, HC3, and HC6 showed high binding affinity to TGFB1 compared to silicic acid as a standard anti-inflammatory drug. Conclusion: These seven peptides can potentially interact with BMP2 or TGFB1 and might have anti-inflammatory capability.

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