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All Journal Indonesian Journal of Cancer Chemoprevention Pharmacon Pharmascience Journal of Islamic Pharmacy CERATA Jurnal Ilmu Farmasi Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Indonesian Journal of Global Health research Indonesian Community Journal Abdi Geomedisains Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Sains dan Praktis Proceeding ISETH (International Summit on Science, Technology, and Humanity) Journal of Pharmaceutical and Sciences. CERATA Jurnal Pengabdian Masyarakat Panacea Usadha Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian Pharmacon: Jurnal Farmasi Indonesia
Erindyah Retno Wikantyasning
Universitas Muhammadiyah Surakarta
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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OPTIMALISASI LAHAN PEKARANGAN DAN TANAMAN EMPON-EMPON DI DESA CABEYAN, BENDOSARI, SUKOHARJO Erindyah Retno Wikantyasning; Setyo Nurwaini; Endang Setyaningsih; Dedi Hanwar; Ika Trisharyanti; Luluk Ria Rakhma; Rima Munawaroh; Zakky Cholisoh; Ambar Yunita Nugraheni; Refsya Azanti; Yuka Aulia Rahma; Sania Nayasari Khoirunnisa; Muhammad Ikhsan Al Af Ghani; Amanda Wahyu Kurniawan; Khoirunnisa Khoirunnisa; Brainandiva Ade Fitria; Audi Tahta Aurellia; Rosi Hayyu Anjani; Cahya Rahma Utami
Abdimas Galuh Vol 4, No 2 (2022): September 2022
Publisher : Universitas Galuh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25157/ag.v4i2.8158

Abstract

Desa Cabeyan di Kecamatan Bendosari, Sukoharjo memiliki lahan pekarangan yang sebagian dimanfaatkan untuk budi daya berbagai tanaman sayur, buah, dan tanaman obat. Tujuan dari kegiatan pengabdian kepada masyarakat ini yaitu untuk mengoptimalkan pemanfaatan lahan pekarangan, terutama untuk budi daya tanaman empon-empon dan pengolahan empon-empon. Sasaran yang dituju yaitu Kelompok Wanita Tani (KWT) desa Cabeyan, agar dapat meningkatkan kesejahteraan melalui pemanfaatan lahan pekarangan. Metode yang digunakan dalam pengabdian ini yaitu dengan edukasi kepada anggota KWT yang disampaikan secara lisan, dilanjutkan dengan praktek pembuatan produk dari empon-empon. Hasil analisis pre-test dan post-test menunjukkan adanya peningkatan pemahaman dari KWT terkait pemanfaatan lahan pekarangan untuk budi daya empon-empon, dari 61% menjadi 86%, dan peningkatan keterampilan dari KWT dalam mengolah empon-empon menjadi produk serbuk minuman instan.     
Formulasi dan Uji Antioksidan Formula Granul Effervescent Ekstrak Kulit Buah Pulasan (Nephelium mutabile Blume) Tribudi Julianti; Ika Ayu Mentari; Erindyah Retno Wikantyasning; Salsabila Azzahra; Indah Hairunisa
Jurnal Pharmascience Vol 9, No 2 (2022): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v9i2.13717

Abstract

Pulasan (Nephelium mutabile Blume) merupakan tanaman yang banyak tumbuh di Kalimatan. Tanaman ini diketahui memiliki aktivitas antioksidan yang tinggi tertutama pada bagian kulitnya akan tetapi pemanfaatan aktivitas ini belum banyak dilakukan. Hal ini dibuktikan dengan kurangnya penelitian mengenai formulasi buah pulasan menjadi sediaan farmasi yang mudah dan menyenangkan untuk digunakan. Penelitian ini bertujuan untuk mendapatkan formula optimum effervescent ekstrak kulit buah pulasan yang dapat diterima dan mudah digunakan setelah itu dikaji aktivitas antioksidan dengan metode 2,2-diphenyl-1-picrylhydrazyl (DPPH) menggunakan spektrofotometer UV-Vis. Pembuatan serbuk effervescent ekstrak kulit buah pulasan dilakukan menggunakan empat formula dengan konsentrasi ekstrak yang berbeda, dilanjutkan dengan uji kestabilan fisik meliputi uji pH, organoleptis, moisture content, waktu alir dan sudut diam. Hasil penelitian menunjukkan tidak ada yang signifikan antara hasil uji organoleptis, pH dan waktu melarut pada ke empat formula yaitu masuk dalam kategori memenuhi syarat. Namun pada uji moisture content dan sudut diam ke empat formula masuk dalam kategori tidak memenuhi syarat. Hasil optimum pada pengujian  antioksidan formula effervescent ekstrak kulit buah pulasan ditunjukkan oleh formula IV ditentukan oleh nilai IC50 826,45 (μg/mL). Hasil penelitian ini menunjukkan ekstrak pulasan dapat diformulasikan dalam bentuk effervescent, tetapi pemilihan konsentrasi ekstrak kulit buah pulasan perlu ditinjau ulang agar didapatkan nilai IC50 yang optimum. Kata Kunci: Effervescent, Pulasan, Antioksidan, DPPH Pulasan (Nephelium mutabile Blume) is a plant that generally grows in Kalimantan. This plant is known to have high antioxidant activity, especially in its peels, but the utilization of this activity has not been widely used. This has been proven by the lack of research on the formulation of this fruit into pharmaceutical preparations that are easy and pleasant to use. The aim of this study was to obtain the optimum effervescent formula for the peel extract of pulasan that acceptable and easy to us and also the antioxidant activity of the formula was assessed using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method using a UV-Vis spectrophotometer. The making of the effervescent powder of the fruit peel extract was carried out using four formulas with different extract concentrations, followed by physical stability tests including pH, organoleptic, moisture content, flow time and angle of repose tests. The results showed that there was no significant difference between the results of the organoleptic test, pH and dissolving time in the four formulas, which were included in the eligible category. However, in the test of moisture content and angle of repose the four formulas are in the category of not meeting the requirements. The optimum results in the antioxidant test of the effervescent formula of the outward skin extract were shown by formula IV determined by the IC50 value of 826.45 (μg/mL). The results of this study indicate that the pulasan peels extract can be formulated in the form of effervescent, but the selection of the concentration of the pulasan peels extract needs to be reviewed in order to obtain the optimum IC50 value.
Front Matters Vol.19, No 2, 2022 Erindyah Retno Wikantyasning
Pharmacon: Jurnal Farmasi Indonesia Vol 19, No 2 (2022)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v19i2.21249

Abstract

NON-ADHERENCE FACTORS TO TUBERCULOSIS TREATMENT IN PULMONARY TUBERCULOSIS PATIENTS IN SURAKARTA CENTRAL GENERAL HOSPITAL, INDONESIA Hidayah Karuniawati; Gayuh Ilham Rahmadi; Erindyah Retno Wikantyasning
Jurnal Farmasi Sains dan Praktis Vol 9 No 2 (May-August 2023)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v9i2.9109

Abstract

Tuberculosis is an infectious disease that must be treated in the long term. One of the therapeutic efficacy factors in tuberculosis treatment is medication adherence by patients. Non-compliance to treatment leads to no achievement of treatment goals, increasing the risk of resistance, mortality, and morbidity. This study analyzed association factors that predicted the influence of the pulmonary tuberculosis patient’s non-adherence to anti-tuberculosis medicines in Surakarta Central General Hospital, Indonesia. The research was analytical research with a cross-sectional approach. The study samples were 80 respondents. The inclusion criteria were patients diagnosed with pulmonary tuberculosis in Surakarta Central General Hospital, aged >17 years old, and patients who received Anti-Tuberculosis Drugs for at least two months. This study used a questionnaire that has been validated. Data were analyzed by bivariate analysis (chi-square or Fisher) and continued by multivariate logistic analysis. Of 80 respondents, there were 30 respondents (37.5%) were non-adherence to taking Tuberculosis (TB) drugs. The predicted factors that influenced non-adherence in taking anti-tuberculosis drugs were beliefs about the medicine of the harm subscale (p = 0.001; OR = 8.167), suffering from drug side effects (p = 0.022; OR = 4.222), and beliefs about the medicine of overuse subscale (p = 0.038; OR = 3.504). The wrong beliefs of patients and side effects may influence patients’ adherence to TB medicines. Counseling and education are needed to improve patients’ beliefs and manage medicines’ side effects.
Formulation and Characterization of Nanoemulsion from Traditional Extracts for Antidiabetic Dzaki Fikri Firdaus Bakri; Muhtadi Muhtadi; Erindyah Retno Wikantyasning
Indonesian Journal of Global Health Research Vol 5 No 3 (2023): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v5i3.2035

Abstract

Diabetes is a degenerative disease with the highest number of sufferers in the world. Traditional medicine naturally uses extracts of plants and animals in great demand. Curse fish or snakehead fish (Channa striata), elephant lempuyang (Zingiber zerumbet L) and rambutan rind (Nephelium lappaceum) are proven to have active ingredients of albumin, quercetin and geraniin as anti-diabetics. Disadvantages of these active compounds, namely having low solubility, permeability and stability, causing a decrease in bioavailability. Self Nano Emulsifying Drug Delivery System (SNEDDS) is a form of nanoemulsion and is a solution for delivering active compounds to increase permeability, stability and solubility of active compounds. The formula was made using olive oil as the oil phase, PEG 400 as the cosurfactant, span 80, tween 20 and tween 80 as the surfactant. The research aims to obtain the optimum nanoemulsion formula using the HLB method. Percent transmittance and emulsification time are used to determine the optimum formula. The selected formula was further tested with a particle size analyzer, zeta potential, PDI. Based on the 30 formulas that were made, F9 was the chosen formula with an HLB value of 15 with the oil, surfactant, cosurfactant phases at a ratio of 8:1:1. Formula F9 has an emulsification time of 18.76 seconds, a transmittance of 97.8%. The particle size test results were 196.2 nm and -30.1 zeta potential values. The research results showed that SNEDDS preparations were able to form nanoemulsions spontaneously and had good characteristics.
SYSTEMATIC LITERATUR REVIEW: SYNTHESIS OF SILVER NANOPARTICLES (AgNPs) USING SECONDARY METABOLITES OF FRUIT PEEL EXTRACT Indana Lazulfa; Erindyah Retno Wikantyasning
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 3 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i3.913

Abstract

The synthesis of silver nanoparticles (AgNPs) using secondary metabolites of biological materials is a simple, cost-effective, and environmentally friendly method compared to physical synthesis methods. The secondary metabolites of the fruit peel extract can be used to synthesize AgNPs. Researchers chose experimental research articles with the theme of silver nanoparticle synthesis using fruit peels for review and selected journals published from 2018 to 2022 from web searches PubMed, Google Schoolar, Scopus, and ScienceDirect. The researchers screened and selected 28 articles according to the inclusion and exclusion criteria. The synthesis of AgNPs using fruit peel extracts can produce stable nanosized AgNPs. Silver nanoparticles synthesized using fruit peels showed stable silver nanoparticle synthesis results in terms of zeta potential and polydispersity index (PDI) values and obtained an average size of 2–200 nm with a spherical shape. Keywords: Silver Nanoparticles, Fruit Peel Extract, Antibacterial agent
Optimisasi Tween 80 dan Span 80 Sebagai Emulgator dalam Formula Krim Tabir Surya Kombinasi Ekstrak Etanol Daun Alpukat (Persea americana M.) dan Nanopartikel Seng Oksida Dengan Metode Simplex Lattice Design Erindyah Retno Wikantyasning; Nabilla Indianie
CERATA Jurnal Ilmu Farmasi Vol 12 No 1 (2021): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v12i1.198

Abstract

Avocado leaves contain flavonoid which act as antioxidant whereas nanoparticles of zinc oxide can protect the skin against a wide spectrum of UV. The purpose of this study was to determine the effect of variation of Tween 80 and span 80 as emulsifier and determine the optimum formula of sunscreen scream containing ethanol extract of avocado leaves and zinc oxide nanoparticles. Avocado leaves were extracted by maceration method using ethanol. Nano zinc oxide is obtained by the High Energy Ball Milling technique and characterized using Particle Size Analyzer. Determination of the optimal cream formula with variations in the concentration of Tween 80 and Span 80 is done by Simplex Lattice Design (SLD) method. The maceration resulted ethanolic extract of avocado leaves with a yield of 34.4%. The synthesised zinc oxide nanoparticles obtained showed 179.47±5.98 nm in diameter. The results showed that increasing concentrations of Tween 80 and decreasing concentration of Span 80 increased spreadability but decreased the viscosity and adhesiveness of creams. The SPF evaluation of creams showed a medium protection category (SPF>15). The optimum formula was obtained with the ratio of Tween 80 and Span 80 was 7,8 and 3,2%, respectively, with the desirability value of 0.863.
SYSTEMATIC LITERATUR REVIEW: SYNTHESIS OF SILVER NANOPARTICLES (AgNPs) USING SECONDARY METABOLITES OF FRUIT PEEL EXTRACT Indana Lazulfa; Erindyah Retno Wikantyasning
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 3 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i3.913

Abstract

The synthesis of silver nanoparticles (AgNPs) using secondary metabolites of biological materials is a simple, cost-effective, and environmentally friendly method compared to physical synthesis methods. The secondary metabolites of the fruit peel extract can be used to synthesize AgNPs. Researchers chose experimental research articles with the theme of silver nanoparticle synthesis using fruit peels for review and selected journals published from 2018 to 2022 from web searches PubMed, Google Schoolar, Scopus, and ScienceDirect. The researchers screened and selected 28 articles according to the inclusion and exclusion criteria. The synthesis of AgNPs using fruit peel extracts can produce stable nanosized AgNPs. Silver nanoparticles synthesized using fruit peels showed stable silver nanoparticle synthesis results in terms of zeta potential and polydispersity index (PDI) values and obtained an average size of 2–200 nm with a spherical shape. Keywords: Silver Nanoparticles, Fruit Peel Extract, Antibacterial agent
PEMBENTUKAN DAN KARAKTERISASI FISIKA KIMIA KO-KRISTAL PIROXICAM-ASAM TARTRAT-SAKARIN DENGAN METODE SOLVENT DROP GRINDING Imanto, Teguh; Pertiwi, Hany Kartika; Wikantyasning, Erindyah Retno
Journal of Islamic Pharmacy Vol 8, No 2 (2023): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v8i2.24449

Abstract

Piroxicam merupakan obat turunan asam enolat (oksikam) sebagai antiinflamasi nonsteroid (NSAID). Piroxicam digunakan untuk mengurangi atau menghilangkan resiko rheumatoid arthritis dan osteoarthritis. Piroxicam dikategorikan sebagai BCS (Biopharmaceutical Classification System) kelas II yaitu memiliki kelarutan rendah dan permeabilitas tinggi. Tujuan dari penelitian ini ialah untuk meningkatkan kelarutan obat piroxicam yang telah termodifikasi ko-kristal pada uji kelarutan dan mengkarakterisasi sifat fisika kimia ko-kristal piroxicam meliputi uji Fourier Transform Infra Red (FTIR), uji Differential Scanning Calorimetry (DSC), uji X-Ray Diffraction (XRD), uji sifat alir, dan uji kerapatan mampat. Pembentukan ko-kristal menggunakan metode Solvent Drop Grinding dengan cara menggerus secara bersama-sama piroxicam, asam tartrat, sakarin selama 15 menit, kemudian ditambahkan sedikit pelarut metanol dan disimpan pada eksikator. Ko-kristal yang terbentuk diuji karakterisasi sifat fisika kimianya. Hasil analisis menunjukkan ko-kristal piroxicam asam tartrat-sakarin perbandingan molar 1:1:1 dalam pelarut HCl 0,1 N memiliki kelarutan yang lebih tinggi dibandingkan piroxicam murni dan ko-kristal piroxicam asam tartrat-sakarin perbandingan molar 2:1:1. Hasil analisis ko-kristal formula 1 (1:1:1) pada uji FTIR menunjukkan panjang gelombang serapan gugus C=O karboksilat yaitu 1736,73 cm-1, hasil uji XRD mengalami penurunan intensitas puncak difraksi pada sudut 8, 14, 17 dan 27o yaitu 1431,23, 1081,58, 1726,28 dan 1228,92 cts. Hasil uji DSC mengalami penurunan titik leleh 163,90oC dan penurunan energi entalpi 53,97J/g. Ko-kristal formula 1 memiliki rata-rata indeks kompresibilitas yaitu 10,8%, hasil uji kelarutan piroxicam dalam pelarut HCl 0,1 N yaitu 59,10 mg/mL.
Edukasi Pencegahan Penyalahgunaan Narkotika pada Remaja Wahyuni, Arifah Sri; Wikantyasning, Erindyah Retno; Nurwaini, Setyo; Ramarohasina, Mika Notahiana; Da’i, Muhammad; Dyahariesti, Niken; Abdellah, Yousra Nait El Haj; Ratsimandresy, Neciah Fahombiazana; Zahidah, Fairus; Yuniasti, Lainisah Purna
Abdimas Galuh Vol 6, No 2 (2024): September 2024
Publisher : Universitas Galuh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25157/ag.v6i2.14393

Abstract

PkM merupakan kegiatan terjun ke masyarakat terkait permasalahan yang dihadapi oleh masyarakat.   Penyalahgunaan narkotika yang semakin merajarela sebanyak 90% adalah remaja. Remaja memiliki peran penting dalam masa depan suatu bangsa dan negara, sebagai generasi penerus yang akan mengambil alih kepemimpinan, meneruskan tradisi, dan menghadapi tantangan di masa depan. Usia remaja adalah usia yang masih labil dalam melakukan sesuatu yang baru dengan mencoba-coba. Kegiatan ini dilakukan di SMA Muhammadiyah 1 Denpasar yang diikuti oleh 240 siswa. Kegiatan diawali dengan pretest, edukasi tentang narkotika dan postest. Edukasi dilakukan dengan pemaparan materi dan video serta diskusi.  Dari hasil pretest  didapatkan sangat baik 0%, baik 0%, cukup 23%, dan kurang 77%; sedangkan hasil  postest didapatkan sangat baik   16%, baik 11%, cukup  49%, dan kurang 24%. Dapat dilihat adanya peningkatan tingkat pengetahuan siswa tentang narkotika. Dari hasil evaluasi yang diberikan didapatkan tingkat pengetahuan siswa masih  kurang di aspek  macam-macam narkotika, hal-hal yang dapat menyebabkan ketergantungan narkotika, dan efek yang ditimbulkan dari penyalahgunaan  narkotika. Dengan adanya hasil ini maka perlu perhatian khusus dari berbagai pihak untuk secara berkala melakukan pendampingan kepada siswa tentang dampak dari penyalahgunaan narkotika. Tingkat pengetahuan siswa tentang narkotika yang tinggi dapat membantu pencegahan penyalahgunaan narkotika terutama di lingkungan terdekat mereka.
Co-Authors Abdellah, Yousra Nait El Haj Amalia Septianawati Amalia, Nastity Zhahwa Amanda Wahyu Kurniawan Ambar Yunita Ambar Yunita Nugraheni Andi Suhendi Arifah Sri Wahyuni Astuti, Devi Dwi Astuti, Kartika Fidi Audi Tahta Aurellia Brainandiva Ade Fitria Cahya Rahma Utami Cholisoh, Zakky Dedi Hanwar Devita Dwitama Setya Divayana, Destria Dwi Anggraini, Adinda Dzaki Fikri Firdaus Bakri Endang Setyaningsih Gayuh Ilham Rahmadi Gunawan Setyadi Hartanto, Riyan Eko Heppy Purbasari Hidayah Karuniawati Ika Ayu Mentari Ika Trisharyanti Dian Kusumowati Indah Hairunisa Indana Lazulfa Indrastuti, Annora Julianti, Tri Budi Karimah, Izqi Kartika Fidi Astuti Khairani, Vita Fadlilah Khoirunnisa Khoirunnisa Larasati, Arindra Luluk Ria Rakhma Lusi Anggraini Muhammad Da'i Muhammad Ikhsan Al Af Ghani Muhtadi Muhtadi Muhtadi, M Nabilla Indianie Niken Dyaharesti Nor Laili Nurhakimah, Ulil Fikri Pertiwi, Hany Kartika Prasetiawan, Roseh Priyastiningrum, Anisa Rachma Putri, Nastity Zhahwa Amalia Ramadhani Dwi Sula Ramarohasina, Mika Notahiana Ramdani, Tasya Eka Ratsimandresy, Neciah Fahombiazana Refsya Azanti Putri Rima Munawaroh Roseh Prasetiawan Rosi Hayyu Anjani Salsabila Azzahra Sania Nayasari Khoirunnisa Sella Aprilia Setyo Nurwaini Shafira Widyanti Sula, Ramadhani Dwi Syamsul Arifin Teguh Imanto Tri Budi Julianti Ulayya, Hanidya Fidela Ulil Fikri Nurhakimah Wahyu Utami, Wahyu Yuka Aulia Rahma Yuniasti, Lainisah Purna Zahidah, Fairus