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All Journal Indonesian Journal of Cancer Chemoprevention Pharmacon Pharmascience Journal of Islamic Pharmacy CERATA Jurnal Ilmu Farmasi Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Indonesian Journal of Global Health research Indonesian Community Journal Abdi Geomedisains Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Sains dan Praktis Proceeding ISETH (International Summit on Science, Technology, and Humanity) Journal of Pharmaceutical and Sciences. CERATA Jurnal Pengabdian Masyarakat Panacea Usadha Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian Pharmacon: Jurnal Farmasi Indonesia
Erindyah Retno Wikantyasning
Universitas Muhammadiyah Surakarta
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Literature Review: Formulation and Characterization of Nanoemulgel for Anticellulite Treatment Ulayya, Hanidya Fidela; Erindyah Retno Wikantyasning
Pharmacon: Jurnal Farmasi Indonesia Volume 21, No 2 (2024)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v21i2.7157

Abstract

Cellulite, a skin condition characterized by a dimpled, orange-peel appearance, commonly affects the thighs, abdomen, hips, and buttocks. Nanoemulgel, a combined system of nanoemulsion and gel, has gained attention as an effective topical drug delivery system, particularly for lipophilic drugs. This review examines the potential of nanoemulgel formulations in treating cellulite, focusing on their physical characteristics, drug delivery efficiency evaluated through skin penetration and anti-cellulite effects, specifically their ability to inhibit adipogenesis and reduce triglycerides. A total of 5 articles were selected for further review as they met the eligibility criteria, including nanoemulgel formulations containing active ingredients with potential anti-cellulite properties and in vitro or in vivo testing for anti-cellulite effectiveness. The results show that nanoemulgel formulations could be a new way to deliver lipophilic drugs to specific areas of the skin for treating cellulite.
Edukasi Penyakit Asam Urat di Desa Dawung Wetan Surakarta Wikantyasning, Erindyah Retno; Wahyuni, Arifah Sri; Julianti, Tri Budi; Amalia, Nastity Zhahwa; Astuti, Devi Dwi
Jurnal Pengabdian Masyarakat Panacea Vol 2, No 4 (2024): Jurnal Pengabdian Masyarakat Panacea
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jpmp.v2i4.14143

Abstract

Prevalensi penyakit tidak menular, termasuk asam urat, semakin meningkat di Indonesia. Pengabdian kepada masyarakat ini menguraikan pelaksanaan kegiatan pengabdian kepada masyarakat yang difokuskan pada penyuluhan penyakit asam urat di Kelurahan Dawung Wetan, Kota Surakarta, Provinsi Jawa Tengah. Penyuluhan ini bertujuan untuk meningkatkan pemahaman masyarakat tentang penyakit asam urat dan mendorong praktik hidup sehat. Metodologi yang digunakan adalah penyuluhan tentang faktor risiko penyakit asam urat kepada ibu-ibu PKK. dan pencegahan penyakit, dilanjutkan dengan sesi tanya jawab, pemberian pretest sebelum penyuluhan, dan posttest setelah penyuluhan untuk menilai tingkat pengetahuan masyarakat. Hasil penelitian menunjukkan bahwa 66,7% peserta memiliki pemahaman yang komprehensif tentang asam urat, sedangkan 33,3% menunjukkan pengetahuan yang memadai. Temuan ini menunjukkan bahwa edukasi yang disampaikan memberikan pemahaman ibu-ibu PKK tentang asam urat meningkat terlihat dari jawaban pretest dan posttest yang diberikan. Meskipun demikian, temuan ini juga memberikan arahan untuk meningkatkan inisiatif edukasi dan pencegahan. Upaya pengabdian masyarakat ini secara efektif meningkatkan pengetahuan masyarakat tentang asam urat dan mendorong penerapan gaya hidup sehat. untuk mewujudkan masyarakat yang lebih sejahtera dan berkualitas. Kata Kunci: Edukasi, Asam Urat, Gaya Hidup Sehat, Kesehatan The prevalence of non-communicable diseases, including gout, is rising in Indonesia. This community service outlines the execution of community service initiatives centred on gout education in Dawung Wetan Village, Surakarta City, Central Java Province. This counselling seeks to enhance public comprehension of gout and encourage healthy lifestyle practices. The methodology entails instructing PKK moms on risk factors and disease prevention, succeeded by a question and answer session, the administration of a pretest prior to counselling, and a posttest subsequent to counselling to assess the community's knowledge level. The findings indicated that 66.7% of participants possessed a comprehensive awareness of gout, whilst 33.3% demonstrated adequate knowledge. These findings suggest educational initiatives aimed at enhancing public comprehension of gout. Nonetheless, these findings also offer direction for enhancing educational and preventive initiatives. This community service effort effectively enhances public knowledge about gout and promotes the adoption of healthy lifestyles to cultivate a more prosperous and quality society.
Peningkatan Pemasaran Produk pada Kelompok Wanita Tani Sri Rejeki di Desa Cabeyan Sukoharjo Nugraheni, Ambar Yunita; Purbasari, Heppy; Utami, Wahyu; Cholisoh, Zakky; Nurwaini, Setyo; Kusumowati, Ika Trisharyanti Dian; Wikantyasning, Erindyah Retno; Munawaroh, Rima; Hanwar, Dedi; Larasati, Arindra; Ramdani, Tasya Eka
Abdi Geomedisains Vol. 6, No. 1, June 2025
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/abdigeomedisains.v6i1.10989

Abstract

Kelompok Wanita Tani (KWT) Sri Rejeki in Cabeyan Village, Sukoharjo, is a community of women actively engaged in plant cultivation and the production of instant herbal products such as ginger and temulawak (curcuma). However, their product marketing activities are still limited to conventional methods and have not yet reached digital marketing platforms. This community service activity aimed to enhance the knowledge and skills of KWT members in digital product marketing through educational sessions and practical training. The methods used included interactive lectures, group discussions, and hands-on practice related to the use of social media and e-commerce platforms. The educational materials covered product marketing and basic understanding of Break Even Point (BEP) calculation. A total of 18 active KWT members and 5 teenagers participated in this activity. The participants' knowledge test results before (pre-test) and after (post-test) the educational session showed an increase in the average knowledge level, from the fair category (63.77%) to the good category (97.10%). KWT members began to understand the importance of market segmentation, slogan development, and the use of digital platforms such as WhatsApp Business, Instagram, and Shopee. This activity demonstrated that participatory training could equip participants with practical skills to improve their product marketing strategies. It is recommended that an internal marketing team be formed and continuous mentoring provided to optimize digital marketing efforts and product legality aspects such as PIRT (Home Industry Food Permit) and halal certification.
OPTIMASI FORMULASI SEDIAAN NANOEMULGEL EKSTRAK ETANOL DAUN BIDARA (Ziziphus mauritiana L.) SEBAGAI ANTI JERAWAT TERHADAP BAKTERI Propionibacterium acnes DAN Staphylococcus aureus Dwi Anggraini, Adinda; Wikantyasning, Erindyah Retno
Usadha Journal of Pharmacy Vol. 4 No. 3 (2025): Agustus
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/ujp.v4i3.737

Abstract

Daun bidara (Ziziphus mauritiana L.) mengandung senyawa flavonoid, alkaloid, fenolik, tanin, dan saponin yang ampuh sebagai antibakteri. Penggunaan daun bidara bidara dapat dimanfaatkan menjadi sediaan gel untuk membantu mengatasi jerawat. Penelitian ini bertujuan mengetahui formula sediaan nanoemulgel dari ekstrak etanol daun bidara yang optimal serta memiliki aktivitas antibakteri. Optimasi dilakukan dengan mengkombinasikan surfaktan dan kosurfaktan menggunakan Design Expert (DE) versi 13 metode Simplex Lattice Design (SLD). Pengujian antibakteri terhadap bakteri Propionibacterium acnes dan Staphylococcus aureus menggunakan metode sumuran. Hasil formula optimal nanoemulsi yang dikembangkan menjadi nanoemulgel diperoleh pada tween 80 dengan konsentrasi 53,473% dan PEG 400 sebesar 26,527% dengan hasil nilai desirability sebesar 0,867.  Hasil uji aktivitas antibakteri nanoemulgel ekstrak etanol daun bidara pada bakteri Propionibacterium acnes menghasilkan zona hambat sebesar 16,8 mm ± 1,2 dengan kategori kuat dan Staphylococcus aureus sebesar 23,5 mm ± 2,6 dengan kategori sangat kuat.
Uji Efektivitas Antihiperurisemia Ekstrak Etanol Kencur (Kaempferia galanga L.) dan Jahe Hitam (Kaempferia parviflora) terhadap Tikus yang Diinduksi Jus Hati Ayam dan Potassium Oxonate Wikantyasning, Erindyah Retno; Wahyuni, Arifah Sri; Julianti, Tri Budi; Putri, Nastity Zhahwa Amalia; Astuti, Devi Dwi
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 3 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i3.497

Abstract

Hyperuricemia is caused by excessive production and/or poor elimination of uric acid. Kencur (Kaempferia galanga L.) and black ginger (Kaemperia parviflora) can be utilised as antihyperurisemic alternatives because their flavonoids block xanthin oxidase (XO). The study determine the efficacy of black ginger ethanol extract (EEJH) as an in vivo antihyperuricemic agent. This research was conducted to determine the effectiveness of kencur ethanol extract (EK) dan black ginger ethanol extract (EEJH) as an antihyperuricemia in vivo. A complete random design used involving 32 mice in 8 groups. Negative control (CMC Na 0.5%); positive control (Allopurinol 10 mg/kgBW); EK and EEJH respectively 12.5; 25; and 50 mg/kgBW. Hyperurisemia was induced by chicken liver juice 4 mL/200 gBB p.o. and potassium oxonate 250 mg/kgBB i.p. UA monitoring was carried out before induction, 0, 7, and 14 days after treatment. Tukey post hoc tests and ANOVA were used to evaluate the data. The results indicate that both of EK and EEJH can reduced UA (p<0.05) however the reduction is significant with Allopurinol (P<0.05). Thus, it can be inferred that the EK and EEJH have potential for enhanced antihyperurysemic in decreasing the UA.
Antioxidant Activity of Nanoemulsion Gel of Rambutan Fruit Peel Extracts (Nephelium lappaceum L.) Using Dpph and FTC Method Muhtadi, M; Hartanto, Riyan Eko; Wikantyasning, Erindyah Retno
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2016: Proceeding ISETH (International Conference on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.2360

Abstract

Rambutan fruit peel extracts had been reported to have quite high antioxidant activity. There are several compounds classes of phenolic and flavonoid contained in Rambutan fruit peel extracts such as ellagic acid, corillagine and geraniine that are responsible for its antioxidant activity. Antioxidant compounds are commonly used in cosmetic preparations. This study was conducted to explain the antioxidant activity of rambutan fruit peel extracts in nanoemulsion gel formulation which was tested with DPPH (1.1-diphenyl-2-picrylhydrazyl) and FTC (Ferric Thiosyanate) method. A method of DPPH was done by making 5 series of concentration and read as absorbance at λ max by using spectrophotometer UV-Vis and for the method of FTC, it was read as absorbance at λ 500 nm. The result of absorbance could be used to determine the value of IC50 (DPPH method) and inhibition percent (FTC method). The result of the study using DPPH method obtained the IC50 values of nanoemulsion gel of Rambutan fruit peel extracts in the amount of 9.32 ± 0.06 mg/mL, which was higher than X® Sunscreen Gel and vitamin E with IC50 value of 40.41 ± 0.98 mg/mL and 10.41 ± 0.05 mg/mL, respectively. The results with the FTC method obtained the percent value of inhibition of 51.09 ± 0.99%, which was lower than X® Sunscreen Gel and vitamin E with percent value of inhibition of 60.07% ± 13.23% and 79.07 ± 7.62%, respectively. These results indicated that Rambutan fruit peel extracts had quite high antioxidant activity that after they were formulated into a nanoemulsion gel.
Edukasi Masyarakat Mengenai Penyakit Tuberkulosis serta Dagusibu (Dapatkan, Gunakan, Simpan, dan Buang Obat) di Wonorejo, Polokarto, Sukoharjo Wikantyasning, Erindyah Retno; Khairani, Vita Fadlilah; Indrastuti, Annora; Priyastiningrum, Anisa Rachma; Divayana, Destria; Karimah, Izqi
Abdimas Galuh Vol 6, No 1 (2024): Maret 2024
Publisher : Universitas Galuh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25157/ag.v6i1.13328

Abstract

Tuberkulosis adalah suatu penyakit kronik menular yang disebabkan oleh bakteri Mycobacterium tuberculosis. Tujuan dilaksanakan kegiatan ini yaitu peserta diharapkan mampu meningkatkan pengetahuan mengenai tuberkulosis. Untuk sasaran dalam kegiatan ini yaitu 34 peserta ibu-ibu Aisyiyah. Kegiatan yang dilakukan berupa edukasi dengan metode penyuluhan dan pembagian leaflet mengenai tuberkulosis dan DAGUSIBU. Kegiatan ini diawali dan diakhiri dengan pengisian kuesioner untuk mengukur pemahaman peserta. Data diuji normalitas dan uji t berpasangan. Berdasarkan hasil analisis uji t-berpasangan antara pre test dan post test, dapat diketahui bahwa nilai P sebesar 0,143 yang artinya p > 0,05 dan nilai t hitung < t critical sehingga tidak ada perbedaan signifikan antara tingkat pengetahuan ibu-ibu sebelum dan setelah dilakukan edukasi. Dapat disimpulkan bahwa hasil pre test sudah baik karena peserta merupakan ibu-ibu kader kesehatan. Untuk program lanjutan akan dilakukan edukasi ke masyarakat oleh ibu-ibu kader yang telah mendapatkan edukasi.
Co-Authors Abdellah, Yousra Nait El Haj Amalia Septianawati Amalia, Nastity Zhahwa Amanda Wahyu Kurniawan Ambar Yunita Ambar Yunita Nugraheni Andi Suhendi Arifah Sri Wahyuni Astuti, Devi Dwi Astuti, Kartika Fidi Audi Tahta Aurellia Brainandiva Ade Fitria Cahya Rahma Utami Cholisoh, Zakky Dedi Hanwar Devita Dwitama Setya Divayana, Destria Dwi Anggraini, Adinda Dzaki Fikri Firdaus Bakri Endang Setyaningsih Gayuh Ilham Rahmadi Gunawan Setyadi Hartanto, Riyan Eko Heppy Purbasari Hidayah Karuniawati Ika Ayu Mentari Ika Trisharyanti Dian Kusumowati Indah Hairunisa Indana Lazulfa Indrastuti, Annora Julianti, Tri Budi Karimah, Izqi Kartika Fidi Astuti Khairani, Vita Fadlilah Khoirunnisa Khoirunnisa Larasati, Arindra Luluk Ria Rakhma Lusi Anggraini Muhammad Da&#039;i Muhammad Ikhsan Al Af Ghani Muhtadi Muhtadi Muhtadi, M Nabilla Indianie Niken Dyaharesti Nor Laili Nurhakimah, Ulil Fikri Pertiwi, Hany Kartika Prasetiawan, Roseh Priyastiningrum, Anisa Rachma Putri, Nastity Zhahwa Amalia Ramadhani Dwi Sula Ramarohasina, Mika Notahiana Ramdani, Tasya Eka Ratsimandresy, Neciah Fahombiazana Refsya Azanti Putri Rima Munawaroh Roseh Prasetiawan Rosi Hayyu Anjani Salsabila Azzahra Sania Nayasari Khoirunnisa Sella Aprilia Setyo Nurwaini Shafira Widyanti Sula, Ramadhani Dwi Syamsul Arifin Teguh Imanto Tri Budi Julianti Ulayya, Hanidya Fidela Ulil Fikri Nurhakimah Wahyu Utami, Wahyu Yuka Aulia Rahma Yuniasti, Lainisah Purna Zahidah, Fairus