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All Journal Indonesian Journal of Cancer Chemoprevention Pharmacon Jurnal Florea Journal of Islamic Pharmacy Jurnal Penelitian Kesehatan Suara Forikes Martabe : Jurnal Pengabdian Kepada Masyarakat CERATA Jurnal Ilmu Farmasi Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Indonesian Journal of Global Health research Indonesian Community Journal Abdi Geomedisains Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Sains dan Praktis Proceeding ISETH (International Summit on Science, Technology, and Humanity) Journal of Pharmaceutical and Sciences. CERATA Jurnal Pengabdian Masyarakat Panacea Usadha Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian Pharmacon: Jurnal Farmasi Indonesia Journal of Pharmascience
Erindyah Retno Wikantyasning
Universitas Muhammadiyah Surakarta
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Peningkatan Pemasaran Produk pada Kelompok Wanita Tani Sri Rejeki di Desa Cabeyan Sukoharjo Nugraheni, Ambar Yunita; Purbasari, Heppy; Utami, Wahyu; Cholisoh, Zakky; Nurwaini, Setyo; Kusumowati, Ika Trisharyanti Dian; Wikantyasning, Erindyah Retno; Munawaroh, Rima; Hanwar, Dedi; Larasati, Arindra; Ramdani, Tasya Eka
Abdi Geomedisains Vol. 6, No. 1, June 2025
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/abdigeomedisains.v6i1.10989

Abstract

Kelompok Wanita Tani (KWT) Sri Rejeki in Cabeyan Village, Sukoharjo, is a community of women actively engaged in plant cultivation and the production of instant herbal products such as ginger and temulawak (curcuma). However, their product marketing activities are still limited to conventional methods and have not yet reached digital marketing platforms. This community service activity aimed to enhance the knowledge and skills of KWT members in digital product marketing through educational sessions and practical training. The methods used included interactive lectures, group discussions, and hands-on practice related to the use of social media and e-commerce platforms. The educational materials covered product marketing and basic understanding of Break Even Point (BEP) calculation. A total of 18 active KWT members and 5 teenagers participated in this activity. The participants' knowledge test results before (pre-test) and after (post-test) the educational session showed an increase in the average knowledge level, from the fair category (63.77%) to the good category (97.10%). KWT members began to understand the importance of market segmentation, slogan development, and the use of digital platforms such as WhatsApp Business, Instagram, and Shopee. This activity demonstrated that participatory training could equip participants with practical skills to improve their product marketing strategies. It is recommended that an internal marketing team be formed and continuous mentoring provided to optimize digital marketing efforts and product legality aspects such as PIRT (Home Industry Food Permit) and halal certification.
PERAN KOMUNIKASI, INFORMASI, DAN EDUKASI (KIE) DALAM MENINGKATKAN PENGETAHUAN MASYARAKAT TENTANG KOLESTEROL DI KAMPUNG HIJAU KOTA BANJARMASIN Purwanto, Aris; Asrining Dhiani, Binar; Santi Hasari, Widarika; Azizah, Nur; Retno Wikantyasning, Erindyah; Nur Chairin Hanifa, Deasy; Mulyani, Evi
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 8, No 8 (2025): MARTABE : JURNAL PENGABDIAN KEPADA MASYARAKAT
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v8i8.%p

Abstract

Banyak faktor yang menjadi penyebab kolesterol tinggi dalam tubuh, jika terlambat diatasi kolesterol tinggi akan membahayakan kesehatan. Sedangkan tingkat pengetahuan dan kesadaran tentang kolesterol dan penanganannya dibeberapa masyarakat masih rendah. Tujuan kegiatan dari pengabdian ini yaitu untuk meningkatkan pengetahuan masyarakat tentang penyakit kolesterol melalui pendekatan Komunikasi, Informasi, dan Edukasi (KIE) dan PIO. Metode pengabdian berupa observasi langsung yang disesuaikan dengan kondisi sosial masyarakat di Kampung hijau, Kecamatan Banjarmasin Timur, Kalimantan Selatan. Hasil pre-test dan post-test menunjukkan terdapat peningkatan pengetahuan masyarakat mengenai kolesterol setelah dilakukan edukasi. Kegiatan ini terbukti efektif dalam meningkatkan pengetahuan masyarakat akan pentingnya pengendalian kolesterol dan diharapkan dapat mempraktikkan gaya hidup sehat
OPTIMASI FORMULASI SEDIAAN NANOEMULGEL EKSTRAK ETANOL DAUN BIDARA (Ziziphus mauritiana L.) SEBAGAI ANTI JERAWAT TERHADAP BAKTERI Propionibacterium acnes DAN Staphylococcus aureus Dwi Anggraini, Adinda; Wikantyasning, Erindyah Retno
Usadha Journal of Pharmacy Vol. 4 No. 3 (2025): Agustus
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/ujp.v4i3.737

Abstract

Daun bidara (Ziziphus mauritiana L.) mengandung senyawa flavonoid, alkaloid, fenolik, tanin, dan saponin yang ampuh sebagai antibakteri. Penggunaan daun bidara bidara dapat dimanfaatkan menjadi sediaan gel untuk membantu mengatasi jerawat. Penelitian ini bertujuan mengetahui formula sediaan nanoemulgel dari ekstrak etanol daun bidara yang optimal serta memiliki aktivitas antibakteri. Optimasi dilakukan dengan mengkombinasikan surfaktan dan kosurfaktan menggunakan Design Expert (DE) versi 13 metode Simplex Lattice Design (SLD). Pengujian antibakteri terhadap bakteri Propionibacterium acnes dan Staphylococcus aureus menggunakan metode sumuran. Hasil formula optimal nanoemulsi yang dikembangkan menjadi nanoemulgel diperoleh pada tween 80 dengan konsentrasi 53,473% dan PEG 400 sebesar 26,527% dengan hasil nilai desirability sebesar 0,867.  Hasil uji aktivitas antibakteri nanoemulgel ekstrak etanol daun bidara pada bakteri Propionibacterium acnes menghasilkan zona hambat sebesar 16,8 mm ± 1,2 dengan kategori kuat dan Staphylococcus aureus sebesar 23,5 mm ± 2,6 dengan kategori sangat kuat.
Uji Efektivitas Antihiperurisemia Ekstrak Etanol Kencur (Kaempferia galanga L.) dan Jahe Hitam (Kaempferia parviflora) terhadap Tikus yang Diinduksi Jus Hati Ayam dan Potassium Oxonate Wikantyasning, Erindyah Retno; Wahyuni, Arifah Sri; Julianti, Tri Budi; Putri, Nastity Zhahwa Amalia; Astuti, Devi Dwi
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 3 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i3.497

Abstract

Hyperuricemia is caused by excessive production and/or poor elimination of uric acid. Kencur (Kaempferia galanga L.) and black ginger (Kaemperia parviflora) can be utilised as antihyperurisemic alternatives because their flavonoids block xanthin oxidase (XO). The study determine the efficacy of black ginger ethanol extract (EEJH) as an in vivo antihyperuricemic agent. This research was conducted to determine the effectiveness of kencur ethanol extract (EK) dan black ginger ethanol extract (EEJH) as an antihyperuricemia in vivo. A complete random design used involving 32 mice in 8 groups. Negative control (CMC Na 0.5%); positive control (Allopurinol 10 mg/kgBW); EK and EEJH respectively 12.5; 25; and 50 mg/kgBW. Hyperurisemia was induced by chicken liver juice 4 mL/200 gBB p.o. and potassium oxonate 250 mg/kgBB i.p. UA monitoring was carried out before induction, 0, 7, and 14 days after treatment. Tukey post hoc tests and ANOVA were used to evaluate the data. The results indicate that both of EK and EEJH can reduced UA (p<0.05) however the reduction is significant with Allopurinol (P<0.05). Thus, it can be inferred that the EK and EEJH have potential for enhanced antihyperurysemic in decreasing the UA.
Antioxidant Activity of Nanoemulsion Gel of Rambutan Fruit Peel Extracts (Nephelium lappaceum L.) Using Dpph and FTC Method Muhtadi, M; Hartanto, Riyan Eko; Wikantyasning, Erindyah Retno
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2016: Proceeding ISETH (International Conference on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.2360

Abstract

Rambutan fruit peel extracts had been reported to have quite high antioxidant activity. There are several compounds classes of phenolic and flavonoid contained in Rambutan fruit peel extracts such as ellagic acid, corillagine and geraniine that are responsible for its antioxidant activity. Antioxidant compounds are commonly used in cosmetic preparations. This study was conducted to explain the antioxidant activity of rambutan fruit peel extracts in nanoemulsion gel formulation which was tested with DPPH (1.1-diphenyl-2-picrylhydrazyl) and FTC (Ferric Thiosyanate) method. A method of DPPH was done by making 5 series of concentration and read as absorbance at λ max by using spectrophotometer UV-Vis and for the method of FTC, it was read as absorbance at λ 500 nm. The result of absorbance could be used to determine the value of IC50 (DPPH method) and inhibition percent (FTC method). The result of the study using DPPH method obtained the IC50 values of nanoemulsion gel of Rambutan fruit peel extracts in the amount of 9.32 ± 0.06 mg/mL, which was higher than X® Sunscreen Gel and vitamin E with IC50 value of 40.41 ± 0.98 mg/mL and 10.41 ± 0.05 mg/mL, respectively. The results with the FTC method obtained the percent value of inhibition of 51.09 ± 0.99%, which was lower than X® Sunscreen Gel and vitamin E with percent value of inhibition of 60.07% ± 13.23% and 79.07 ± 7.62%, respectively. These results indicated that Rambutan fruit peel extracts had quite high antioxidant activity that after they were formulated into a nanoemulsion gel.
Edukasi Masyarakat Mengenai Penyakit Tuberkulosis serta Dagusibu (Dapatkan, Gunakan, Simpan, dan Buang Obat) di Wonorejo, Polokarto, Sukoharjo Wikantyasning, Erindyah Retno; Khairani, Vita Fadlilah; Indrastuti, Annora; Priyastiningrum, Anisa Rachma; Divayana, Destria; Karimah, Izqi
Abdimas Galuh Vol 6, No 1 (2024): Maret 2024
Publisher : Universitas Galuh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25157/ag.v6i1.13328

Abstract

Tuberkulosis adalah suatu penyakit kronik menular yang disebabkan oleh bakteri Mycobacterium tuberculosis. Tujuan dilaksanakan kegiatan ini yaitu peserta diharapkan mampu meningkatkan pengetahuan mengenai tuberkulosis. Untuk sasaran dalam kegiatan ini yaitu 34 peserta ibu-ibu Aisyiyah. Kegiatan yang dilakukan berupa edukasi dengan metode penyuluhan dan pembagian leaflet mengenai tuberkulosis dan DAGUSIBU. Kegiatan ini diawali dan diakhiri dengan pengisian kuesioner untuk mengukur pemahaman peserta. Data diuji normalitas dan uji t berpasangan. Berdasarkan hasil analisis uji t-berpasangan antara pre test dan post test, dapat diketahui bahwa nilai P sebesar 0,143 yang artinya p > 0,05 dan nilai t hitung < t critical sehingga tidak ada perbedaan signifikan antara tingkat pengetahuan ibu-ibu sebelum dan setelah dilakukan edukasi. Dapat disimpulkan bahwa hasil pre test sudah baik karena peserta merupakan ibu-ibu kader kesehatan. Untuk program lanjutan akan dilakukan edukasi ke masyarakat oleh ibu-ibu kader yang telah mendapatkan edukasi.
Enhancing the Bioavailability of Noni Fruit (Morinda citrifolia L.) Through Nanotechnology as a Topical Anti-Aging Formulation Sari, Erlinda Novita; Wikantyasning, Erindyah Retno; Utami, Wahyu
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 17, No 1 (2026): January 2026
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf170119

Abstract

Premature aging reduces collagen production and activates MAPK and MMPs pathways. Continuous use of retinol may cause adverse effects; therefore, natural ingredients are recommended as alternative therapies. Noni fruit (Morinda citrifolia L.) has potential anti-aging properties; however, its polyphenolic compounds are sensitive and exhibit limited skin absorption. The application of nanotechnology may address these bioavailability challenges. This review aimed to identify, analyze, and provide evidence regarding the enhancement of bioavailability of Indonesian herbal plants through nanotechnology-based topical formulations for managing skin aging. A systematic literature review was conducted by searching accredited national and international journals indexed in Google Scholar using the keywords “Aging,” “Morinda citrifolia L.,” and “Nano” from 2014 to 2024. From 2,950 identified articles, 80 met the inclusion criteria. The findings indicate that noni fruit contains diverse bioactive compounds with significant anti-aging potential. It is rich in vitamin C, flavonoids, and phenolic compounds. Nanoparticle formulations of noni fruit enhance its anti-aging efficacy through multiple mechanisms and improve the permeation of active compounds into the skin. In conclusion, noni fruit demonstrates strong potential as a topical anti-aging agent, and its limitations can be overcome through nanoparticle-based technology, thereby increasing its therapeutic, functional, and economic value.Keywords: aging; Morinda citrifolia L.; nanotechnology
Formulasi dan Uji Antioksidan Formula Granul Effervescent Ekstrak Kulit Buah Pulasan (Nephelium mutabile Blume) Tribudi Julianti; Ika Ayu Mentari; Erindyah Retno Wikantyasning; Salsabila Azzahra; Indah Hairunisa
Journal of Pharmascience Vol. 9 No. 2 (2022): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v9i2.13717

Abstract

Pulasan (Nephelium mutabile Blume) merupakan tanaman yang banyak tumbuh di Kalimatan. Tanaman ini diketahui memiliki aktivitas antioksidan yang tinggi tertutama pada bagian kulitnya akan tetapi pemanfaatan aktivitas ini belum banyak dilakukan. Hal ini dibuktikan dengan kurangnya penelitian mengenai formulasi buah pulasan menjadi sediaan farmasi yang mudah dan menyenangkan untuk digunakan. Penelitian ini bertujuan untuk mendapatkan formula optimum effervescent ekstrak kulit buah pulasan yang dapat diterima dan mudah digunakan setelah itu dikaji aktivitas antioksidan dengan metode 2,2-diphenyl-1-picrylhydrazyl (DPPH) menggunakan spektrofotometer UV-Vis. Pembuatan serbuk effervescent ekstrak kulit buah pulasan dilakukan menggunakan empat formula dengan konsentrasi ekstrak yang berbeda, dilanjutkan dengan uji kestabilan fisik meliputi uji pH, organoleptis, moisture content, waktu alir dan sudut diam. Hasil penelitian menunjukkan tidak ada yang signifikan antara hasil uji organoleptis, pH dan waktu melarut pada ke empat formula yaitu masuk dalam kategori memenuhi syarat. Namun pada uji moisture content dan sudut diam ke empat formula masuk dalam kategori tidak memenuhi syarat. Hasil optimum pada pengujian  antioksidan formula effervescent ekstrak kulit buah pulasan ditunjukkan oleh formula IV ditentukan oleh nilai IC50 826,45 (μg/mL). Hasil penelitian ini menunjukkan ekstrak pulasan dapat diformulasikan dalam bentuk effervescent, tetapi pemilihan konsentrasi ekstrak kulit buah pulasan perlu ditinjau ulang agar didapatkan nilai IC50 yang optimum. Kata Kunci: Effervescent, Pulasan, Antioksidan, DPPH Pulasan (Nephelium mutabile Blume) is a plant that generally grows in Kalimantan. This plant is known to have high antioxidant activity, especially in its peels, but the utilization of this activity has not been widely used. This has been proven by the lack of research on the formulation of this fruit into pharmaceutical preparations that are easy and pleasant to use. The aim of this study was to obtain the optimum effervescent formula for the peel extract of pulasan that acceptable and easy to us and also the antioxidant activity of the formula was assessed using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method using a UV-Vis spectrophotometer. The making of the effervescent powder of the fruit peel extract was carried out using four formulas with different extract concentrations, followed by physical stability tests including pH, organoleptic, moisture content, flow time and angle of repose tests. The results showed that there was no significant difference between the results of the organoleptic test, pH and dissolving time in the four formulas, which were included in the eligible category. However, in the test of moisture content and angle of repose the four formulas are in the category of not meeting the requirements. The optimum results in the antioxidant test of the effervescent formula of the outward skin extract were shown by formula IV determined by the IC50 value of 826.45 (μg/mL). The results of this study indicate that the pulasan peels extract can be formulated in the form of effervescent, but the selection of the concentration of the pulasan peels extract needs to be reviewed in order to obtain the optimum IC50 value.
Dillapiole-Rich Piper aduncum L.: Phytochemistry, Bioactivity, and Pharmaceutical Applications – A Systematic Review Yahya Febrianto; Erindyah Retno Wikantyasning; Ratna Yuliana
Florea : Jurnal Biologi dan Pembelajarannya Vol. 13 No. 2 (2026)
Publisher : UNIVERSITAS PGRI MADIUN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25273/florea.v13i2.24389

Abstract

The growing interest in the development of phytopharmaceuticals derived from traditional medicinal plants has driven in-depth exploration of Piper aduncum L., a species with diverse therapeutic potential that has not yet been systematically consolidated. This systematic review aims to identify, analyze, and synthesize recent scientific evidence regarding the phytochemical constituents, pharmacological activities, and pharmaceutical development prospects of P. aduncum based on publications from 2021 to 2025. The study adopted the PRISMA 2020 framework, conducting a comprehensive search across five electronic databases using a combination of keywords related to the phytochemistry and pharmacology of P. aduncum. Literature selection was performed through three stages, resulting in six articles that met the inclusion criteria, consisting of two in vivo studies, three laboratory experimental studies, and one systematic review. Methodological quality assessment was conducted using the Modified Downs and Black Checklist and the SYRCLE’s Risk of Bias Tool, followed by systematic data extraction and qualitative narrative synthesis. The findings indicate that dillapiole is the predominant component of the essential oil, with concentrations ranging from 77.6–85.5%, exhibiting antiparasitic, acaricidal, antimycobacterial, immunomodulatory, and anti-inflammatory activities through mechanisms involving modulation of detoxification enzymes and intestinal microbiota. The development of nanocarrier systems has produced stable nanometric formulations with an excellent safety profile for topical applications. This review confirms the significant potential of P. aduncum as a candidate for the development of biopesticides, alternative antimicrobial agents, and phytogenic feed additives. However, further translational research is required, including extraction standardization, investigation of molecular mechanisms, pharmacokinetic–pharmacodynamic studies, long-term toxicological evaluation, and clinical trials to validate efficacy and safety prior to therapeutic application in humans.
Literature Review: Formulation and Characterization of Nanoemulgel for Anticellulite Treatment Hanidya Fidela Ulayya; Erindyah Retno Wikantyasning
Pharmacon: Jurnal Farmasi Indonesia Vol. 21 No. 2 (2024)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v21i2.7157

Abstract

Cellulite, a skin condition characterized by a dimpled, orange-peel appearance, commonly affects the thighs, abdomen, hips, and buttocks. Nanoemulgel, a combined system of nanoemulsion and gel, has gained attention as an effective topical drug delivery system, particularly for lipophilic drugs. This review examines the potential of nanoemulgel formulations in treating cellulite, focusing on their physical characteristics, drug delivery efficiency evaluated through skin penetration and anti-cellulite effects, specifically their ability to inhibit adipogenesis and reduce triglycerides. A total of 5 articles were selected for further review as they met the eligibility criteria, including nanoemulgel formulations containing active ingredients with potential anti-cellulite properties and in vitro or in vivo testing for anti-cellulite effectiveness. The results show that nanoemulgel formulations could be a new way to deliver lipophilic drugs to specific areas of the skin for treating cellulite.
Co-Authors Abdellah, Yousra Nait El Haj Amalia Septianawati Amalia, Nastity Zhahwa Amanda Wahyu Kurniawan Ambar Yunita Nugraheni Andi Suhendi Arifah Sri Wahyuni Astuti, Devi Dwi Astuti, Kartika Fidi Audi Tahta Aurellia Binar Asrining Dhiani Brainandiva Ade Fitria Cahya Rahma Utami Dedi Hanwar Devita Dwitama Setya Divayana, Destria Dwi Anggraini, Adinda Dzaki Fikri Firdaus Bakri Endang Setyaningsih Evi Mulyani Gayuh Ilham Rahmadi Gunawan Setyadi Hanidya Fidela Ulayya Hartanto, Riyan Eko Heppy Purbasari Hidayah Karuniawati Ika Ayu Mentari Ika Trisharyanti Dian Kusumowati Indah Hairunisa Indana Lazulfa Indrastuti, Annora Julianti, Tri Budi Karimah, Izqi Kartika Fidi Astuti Khairani, Vita Fadlilah Khoirunnisa Khoirunnisa Larasati, Arindra Luluk Ria Rakhma Lusi Anggraini Muhammad Da&#039;i Muhammad Ikhsan Al Af Ghani Muhtadi Muhtadi Muhtadi, M Nabilla Indianie Niken Dyaharesti Nor Laili Nur Azizah Nur Chairin Hanifa, Deasy Nur ‘Azah Nurhakimah, Ulil Fikri Pertiwi, Hany Kartika Prasetiawan, Roseh Priyastiningrum, Anisa Rachma Putri, Nastity Zhahwa Amalia Ramadhani Dwi Sula Ramarohasina, Mika Notahiana Ramdani, Tasya Eka Ratna Yuliana Ratsimandresy, Neciah Fahombiazana Refsya Azanti Putri Rima Munawaroh Roseh Prasetiawan Salsabila Azzahra Sania Nayasari Khoirunnisa Santi Hasari, Widarika Sari, Erlinda Novita Sella Aprilia Setyo Nurwaini Shafira Widyanti Sula, Ramadhani Dwi Syamsul Arifin Teguh Imanto Tri Budi Julianti Ulil Fikri Nurhakimah Utami, Wahyu Wahyu Utami Yahya Febrianto Yuka Aulia Rahma Yuniasti, Lainisah Purna Zahidah, Fairus Zakky Cholisoh