Article Per Year (5 Year)
p-Index From 2021 - 2026
4.055
P-Index
This Author published in this journals
All Journal Jurnal Biologi dan Pembelajarannya (JBP) Bioma : Jurnal Biologi Indonesia Jurnal Kreativitas PKM Jurnal Review Pendidikan dan Pengajaran (JRPP) JURNAL Al-AZHAR INDONESIA SERI SAINS DAN TEKNOLOGI Bioscientist : Jurnal Ilmiah Biologi EduBiologia: Biological Science and Education Journal Jurnal Abdimas Bina Bangsa Indonesian Red Crescent Humanitarian Journal Biocaster : Jurnal Kajian Biologi Prosiding Seminar Nasional Pemberdayaan Masyarakat (SENDAMAS) EDUKASI Journal of Engineering and Technological Sciences Science Get Journal
Kun Mardiwati Rahayu
Universitas Al-Azhar Indonesia
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

Published : 26 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 26 Documents
Search

 1   2   3 
Aktivitas Antibakteri Ekstrak Daun Angsana (Pterocarpus indicus) terhadap Staphylococcus aureus dan Salmonella typhimurium Kun Mardiwati Rahayu; Syaharani Latifah
Jurnal Biologi dan Pembelajarannya (JB&P) Vol 13 No 1 (2026): APRIL 2026
Publisher : Universitas Nusantara PGRI Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29407/jbp.v13i1.28604

Abstract

Bacterial infections caused by Staphylococcus aureus and Salmonella typhimurium remain a global health problem, particularly with increasing antibiotic resistance. This study aims to analyze the phytochemical profile and test the antibacterial activity of angsana (Pterocarpus indicus) leaf extract against these two bacteria. The study used an experimental method with a Completely Randomized Design (CRD) consisting of four extract concentrations (10%, 20%, 40%, and 80%), a positive control (chloramphenicol), and a negative control (DMSO), each with six replications. Antibacterial activity was tested using the Kirby-Bauer disc diffusion method, with the observation parameter being the diameter of the inhibition zone. The results showed that angsana leaf extract had concentration-dependent antibacterial activity against Staphylococcus aureus and Salmonella typhimurium, with the highest inhibition at 80% concentration of 19.69 mm and 19.24 mm, respectively (strong category). Comparatively, Salmonella typhimurium was more sensitive at medium concentrations, while Staphylococcus aureus showed a higher response at maximum concentrations. Although the extract's activity was still lower than chloramphenicol, these results demonstrate the potential of angsana leaf extract as a broad-spectrum antibacterial agent against both Gram-positive and Gram-negative bacteria. Therefore, angsana leaf extract has the potential to be developed as an alternative or complementary therapy in controlling bacterial infections, although further research is needed to optimize its effectiveness and further examine its mechanism of action.
Metabolit Sekunder Daun Ganyong (Canna indica L) Kun Mardiwati Rahayu; Kintan Ayu Gustiananda
Prosiding Seminar Nasional Pemberdayaan Masyarakat (SENDAMAS) Vol 5, No 1 (2025): Desember 2025
Publisher : UniversitasAl Azhar Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36722/psn.v5i1.5248

Abstract

Indonesia memiliki keanekaragaman hayati tertinggi di dunia, salah satunya adalah tanaman Canna. Canna indica L. dikenal sebagai tanaman ganyong sering dimanfaatkan sebagai bahan pangan karena termasuk golongan umbi-umbian. Selain umbi, bagian lain pada tanaman ini yang memiliki potensi lain adalah daun yang juga memiliki potensi sebagai herbal. Tanaman ganyong diketahui dapat tumbuh di bawah naungan pohon lain. Naungan pada suatu tanaman dapat memengaruhi kondisi serta senyawa yang terkandung. Penelitian ini bertujuan untuk mengidentifikasi kandungan metabolit sekunder pada daun ternaung dan tidak ternaung. Metode yang digunakan untuk mendapatkan ekstrak etanol daun Canna indica L adalah maserasi. Hasil penelitian yang diperoleh pada daun dengan naungan didapati mengandung metabolit sekunder meliputi flavonoid, alkaloid, polifenol, saponin, glikosida dan tanin. Hasil kandungan metabolit sekunder pada daun tidak ternaung meliputi kandungan yaitu alkaloid, polifenol, saponin, glikosida dan tanin.Kata Kunci - Canna indica L., Ganyong, Metabolit sekunder.
Evaluation of Microplastic Content in Human Circulatory System and Its Potential Impacts on Systemic Health Kun Mardiwati Rahayu; Mila Sari; Pratiwi Ratih Halimatus Sya'diah
Science Journal Get Press Vol 3 No 1 (2026): January, 2026
Publisher : CV. Get Press Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69855/science.v3i1.357

Abstract

Given the escalating global production of plastics and the absence of regulatory frameworks addressing internal human exposure, microplastic contamination has emerged as an urgent environmental and public health policy concern.Using micro Fourier transform infrared spectroscopy (FTIR) and Raman spectroscopy, MPs were detected in 76.0% of samples collected from 50 healthy adults, with an average concentration of 3.15 ± 1.25 particles/mL and a mean particle size of 5.8 ± 2.1 μm. Polyethylene terephthalate (PET) and polypropylene (PP) were the dominant polymer types, while fragments and fibers represented the most common morphologies. Correlation analyses revealed significant positive associations between total MP concentration and inflammatory biomarkers C-reactive protein (r = +0.415, p = 0.003) and interleukin-6 (r = +0.288, p = 0.043) as well as oxidative stress marker malondialdehyde (r = +0.350, p = 0.013), suggesting that MPs may contribute to subclinical systemic inflammation and oxidative imbalance. These findings provide empirical evidence supporting the systemic circulation of MPs and their potential role as low-grade biological stressors that could influence vascular homeostasis. Further longitudinal and mechanistic studies are warranted to elucidate causal pathways, characterize nanoplastic fractions, and establish standardized analytical protocols. This research underscores the growing necessity to treat microplastic exposure as a critical environmental and public health issue.
Efektivitas Antibakteri Ekstrak Daun Jengkol (Pithecellobium jiringa) terhadap Pertumbuhan Salmonella typhimurium: Studi In Vitro Menggunakan Metode Difusi Cakram Kun Mardiwati Rahayu; Anastasia Chairani
Biocaster : Jurnal Kajian Biologi Vol. 5 No. 3 (2025): July
Publisher : Lembaga Pendidikan, Penelitian, dan Pengabdian Kamandanu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/biocaster.v5i3.477

Abstract

Salmonella typhimurium bacterial infection remains one of the main causes of gastrointestinal diseases, and cases of resistance to conventional antibiotics are increasing. This encourages the search for alternative therapies based on natural ingredients, one of which is jengkol leaves (Pithecellobium jiringa) which are known to contain antibacterial compounds. This study is an in vitro experimental study aimed at evaluating the antibacterial effectiveness of ethyl acetate extract of jengkol leaves (Pithecellobium jiringa) against the growth of Salmonella typhimurium using the Kirby-Bauer disc diffusion method. Four extract concentrations (10%, 20%, 40%, and 80%) were tested against bacterial suspensions with chloramphenicol as a positive control, and DMSO as a negative control. Data were analyzed using one-way ANOVA and continued with Duncan's test to determine significant differences between treatments. The results showed a significant increase in the diameter of the inhibition zone as the extract concentration increased with the highest effectiveness at a concentration of 80% (mean inhibition zone 16.07 mm; strong category). Analysis shows that active compounds, such as flavonoids, tannins, and saponins, work through cell wall damage and bacterial membrane permeability. These findings indicate that jengkol leaf extract has potential as a natural antibacterial agent against gram-negative bacteria such as Salmonella typhimurium and is worthy of further development in phytopharmaceutical-based infection control efforts.
One-dimensional Photonic Crystal with Defects to Detect Gelatine Containing Water Ary Syahriar; Nafis Riffat Syahriar; Muhamad Giri Suada; Kun Mardiwati Rahayu; Octarina Nur samijayani; Ahmad Husin Lubis
Journal of Engineering and Technological Sciences Vol. 58 No. 5 (2026): Vol. 58 No. 5(2026): October
Publisher : Directorate for Research and Innovation, Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.eng.technol.sci.2026.58.5.4

Abstract

Gelatine is commonly found in food, pharmaceutical, health, and cosmetic products. However, its use has generated significant debate due to concerns about the numerous sources, particularly for religious reasons. For Muslims and Jews, gelatine derived from porcine sources must be avoided, as it is strictly prohibited by religious laws. The detection in these products is important, and this led to the design of an optical biosensor based on a one-dimensional (1D) photonic crystal (PhC) with a defect layer. The aim was to detect the distinctive characteristics of gelatine with high sensitivity. Additionally, the defect layer was placed in the center of the structure, where the gelatine solution was introduced. The designed PhC structure consisted of N layers of (ZnO/SiO₂)ᴺ/defect/(ZnO/SiO₂)ᴺ. The reflectance and transmittance characteristics of the PhC were calculated by using the transfer matrix method (TMM), performed with the MATLAB software. For simplicity, the normal incidence of light on the PhC was assumed to avoid the complexities of oblique angles. Sensor performance was evaluated by calculating sensitivity (S), quality factor (Q), figure of merit (FOM), resolution (RS), and detection limit (LOD). The biosensor achieved an average S, Q, FOM, RS, and LOD of 225.7694 nm/RIU, 2249.413, 806.3185, 0.1332, and 4.13 × 10⁻⁵, respectively. These metrics showed the simple PhC design was a highly sensitive, non-invasive detection platform for monitoring and identifying gelatine-based products that did not meet Halal and Kosher requirements. The novelty of the study centered on the application of a simple 1D PhC with a defect cavity to detect gelatine concentrations in both aqueous and oily solutions, a problem that had not been addressed in detail.
Local Plastic-Eating Bacteria: The Key to Bioremediation in Indonesian Coastal Waters Kun Mardiwati Rahayu; Yuli Hardina
Science Journal Get Press Vol 3 No 3 (2026): July,2026
Publisher : CV. Get Press Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69855/science.v3i3.712

Abstract

Marine plastic pollution is a critical environmental problem in Indonesian coastal waters, where inadequate waste management and high population density contribute substantially to plastic leakage into the marine environment. Indigenous plastic-degrading bacteria offer a potentially low-cost bioremediation strategy, yet locally isolated strains remain poorly characterized. This study aimed to isolate, screen, and molecularly identify indigenous bacteria capable of degrading polyethylene terephthalate (PET) and low-density polyethylene (LDPE) from seawater, sediment, and plastic-debris samples collected at three stations in Bungus Bay, Padang City, West Sumatra. From 42 morphologically distinct colonies, five isolates with the largest clear zones were selected and identified through 16S rRNA gene sequencing as strains related to Bacillus cereus, Pseudomonas aeruginosa, Rhodococcus ruber, Achromobacter xylosoxidans, and Bacillus subtilis. Quantitative degradation assays conducted in triplicate over 90 days showed that a three-isolate consortium achieved the highest weight loss of PET (16.3%) and LDPE (11.2%), significantly exceeding single-isolate treatments and abiotic controls (ANOVA, Duncan’s test, p < 0.05). FTIR analysis confirmed polymer oxidation, with carbonyl indices increasing from 0.18 to 0.34 for PET and from 0.05 to 0.21 for LDPE. These findings demonstrate considerable biodegradation potential under laboratory conditions, although field validation is required before in-situ application for marine bioremediation purposes.
Co-Authors Abdul Kadir Ahmad Ahmad Husin Lubis Ahmad, Abdul Kadir Alianzar, Muhammad Himawan Amalina Ratih Puspa Anastasia Chairani Andikha Bima Prasetyo Ary Syahriar Asmin Asmin, Asmin Baehaqi Budiningsih Siregar Cholidhazia, Putri Dewi Elfidasari Dhea Hanun Nabila Dira Syafira Djarot, Ira Nurhayati Ema Komalasari Gayatri Atmadi Hidayat Yorianta Sasaerila Iin Kurnia Imsar Gunawan Indriati, Rosita Ira Nurhayati Djarot Kintan Ayu Gustiananda Lutfiana Fazat Azizah Machmud, Aris Mila Sari Muhamad Giri Suada Muhammad Rizqi Nafis Riffat Syahriar Najuwa Najuwa Nida, Khairun Nita Noriko Nurhafifa, Diani Nurul Khofifah, Rizki Aulia Nurul Robbi Sepang Parameswari, Shahnaz Kintan Pratiwi Ratih Halimatus Sya'diah Prawestri, Retno Puspitasari, Ririrs Lindiawati Ribath Ridwanulloh Riris Lindiawati Puspitasari Samijayani, Octarina Nur SANTI LISNAWATI Siti Nurhaliza SUMARNI Supriyanto, Arif Syafitri Jumianto Syaharani Latifah Syaharani, Septi Syariful Syariful Utama, I Wayan Karang Vandan Wiliyanti Wendy Almira Kintoko Winarti Winarti Yuli Hardina