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All Journal JBIO: jurnal biosains (the journal of biosciences) Proceedings of Annual International Conference Syiah Kuala University - Life Sciences & Engineering Chapter Jurnal Ilmu Pertanian KULTIVAR Saintia Biologi AGROEKOTEKNOLOGI Dentika Dental Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research IJOEP : International Journal of Ecophysiology International Journal Of Science, Technology & Management (IJSTM) Archives of The Medicine and Case Reports Bioscientia Medicina : Journal of Biomedicine and Translational Research

Syafruddin Ilyas

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Author-ID : 1157372

Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Transportation Other

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PENGARUH PEMBERIAN VITAMIN C DAN E TERHADAP GAMBARAN HISTOLOGIS TESTIS MENCIT (Mus musculus L.) YANG DIPAJANKAN MONOSODIUM GLUTAMAT (MSG) Ummi Kalsum; Syafruddin Ilyas; Salomo Hutahaean
Saintia Biologi Vol 1, No 3 (2013)
Publisher : Saintia Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (360.802 KB)

The aim of this study is to determine the effect of vitamin C and E on testicular histology of mice following exposure to monosodium glutamate (MSG) for 30 days. Completely Randomized Design (CRD) consisting of 6 treatments and 5 replications was used in this experiment. Mice were treated daily by oral gavage with 4 mg MSG (P1), 4 mg MSG + 0,26 mg vitamin C (P2), 4 mg MSG + 0,026 vitamin E (P3), and 4 mg MSG + 0,26 mg vitamin C + 0,026 mg vitamin E (P4). All dosages (mg/g) were given based on body weight. Two control groups K- and K+ treated with water and castor oil respectively. The results showed that MSG decrease testis weight and its volume (P<0,05), MSG also decrease the diameter of seminiferous tubule and the number of spermatogenic cells. Vitamin C recovers testis weight (P<0,05), but cannot recover its volume, diameter of seminiferous tubules and the number spermatogenic cells (P>0,05). Vitamin E increases the weight and volume of the testes and spermatogenic cells (P<0,05), but unable to recover diameter of the seminiferous tubules (P>0,05). The combination of vitamin C and E recover testis weight and its volume, seminiferous tubule diameter and number of spermatogenic cells (P<0,05). Keywords: Monosodium Glutamate, Vitamin C, Vitamin E, Testis

PENGUJIAN RESPONS PERTUMBUHAN BEBERAPA VARIETAS PADI SAWAH (Oryza sativa L.) AKIBAT CEKAMAN SALINITAS Herti Folarida Hutajulu; Rosmayati Rosmayati; Syafruddin Ilyas
Jurnal Agroekoteknologi Vol 1, No 4 (2013)
Publisher : Universitas Sumatera Utara

Growth Response Testing of Several Rice Varieties (Oryza sativa L.) Caused of Salinity. In theSub-District Percut Sei Tuan there are around 700 hectares more area paddy fields that can becategorized as has been affected by sea water (is 1-2 km to coast). The production rice fields in thearea was around 2-3 tons per hectare with using varieties Ciherang and Mekongga. But varietiesCiherang have potential result8.5 tonnes/ha with result average 6.0 tonnes/ha in the non- salinity.The problem is to be a basic idea how to increase production the be examined back some varietiesthat had been found varieties that not only could but critical market result in standard national resultrice that is 6.0 ton/ha.This study aims to determine the growth response of some rice varieties due tosalinity stress. The study was conducted in the Village of Tanjung Rejo, Hamlet Paluh Merbau, Sub-District Percut Sei Tuan, Deli Serdang Regency with altitude of 1.5 meters above sea level in April-September 2012 using a Randomized Block Design with eight varieties of rice plant (Ciherang, IR64 , Lambur, Batanghari, Banyuasin, IR 42, Inpari 10 and Margasari) with 3 replication. Parameter isobserved germination, salt injury, plant height, number of tillers, leaf chlorophyll, leaf area, numberof productive tillers, panicle length, number of grains contains per panicle, number of grains perpanicle empty, grain weight per plot, and 1000 grain weight. The results showed that Ciherangvarieties and Banyuasin is highly tolerant to salinity. Banyuasin and Batanghari production per plothad the highest and lowest are IR 64 varieties and Inpari 10 varieties.Keywords: salinity, varieties, paddy.

Description of Kidney Histology of Mus Musculus After Giving Nano Hebal Rhodomyrtus tomentosa (Haramounting) Syafruddin Ilyas
International Journal of Ecophysiology Vol. 1 No. 1 (2019): International Journal of Ecophysiology
Publisher : Talenta Publisher

The objective of this study was to determine the description of kidney histology of Mus musculus after giving Nano Herbal Rhodomyrtus tomentosa (Haramonting). R.tomentosa (Haramonting) is made on a nanoscale using High Energy Milling (HEM). This research use the Completely Randomized Design (CRD), which consists of six groups of CMC 0.5% and Nano- R.tomentosa (Haramonting) at dosage of (100; 141,42; 200; 282,82; 400)mg/20g body weight. The kidneys were made into preparations by using the paraffin method and Hematoxylin Erlich-Eosin staining (HE). The results of histological kidneys showed that there is a significant difference (P<0,05) between control group and treatment groups with damaged cells and increased proximal tubular narrowing in kidneys, but there was not significantly different in weight of kidneys (P>0,05).

Effect of Nano herbal Haramounting (Rhodomyrtus tomentosa) in Histology of Heart Mus musculus Syafruddin Ilyas
International Journal of Ecophysiology Vol. 1 No. 2 (2019): International Journal of Ecophysiology
Publisher : Talenta Publisher

The objective of this study was to determine the effect of histology of heart Mus musculus after giving Nano Herbal Rhodomyrtus tomentosa (Haramonting). R.tomentosa (Haramonting) is made on a nanoscale using High Energy Milling (HEM). This research use the Completely Randomized Design (CRD). Treatment consists of 6 groups, namely: Control: CMC 0.5%; T1:100mg/20gBW; T2: 141,42mg/20gBW; T3:200mg/20gBW; T4: 282,82mg/20gBW; T5:400mg/20gBW. The results of histology hearts that there were significant difference (P<0,05) between control group and treatment groups but there was not significantly different in weight of hearts (P>0,05).

Effect of Nanoherbal Haramonting (Rhodomyrtus tomentosa) on Lungs Histology Syafruddin Ilyas
International Journal of Ecophysiology Vol. 2 No. 1 (2020): International Journal of Ecophysiology
Publisher : Talenta Publisher

The study aim to know to effect of Nanoherbal Rhodomyrtus tomentosa (Haramonting) on lungs histology of Mus musculus. Haramonting in Indonesia as a new source of health-promoting compounds such as dietary fibers, essential fatty acids, and phenolic compounds because there are 19 phenolic compounds including stilbenes and ellagitannins as major components, followed by anthocyanins, flavonols, and gallic acid. Haramonting is made on a nanoscale using High Energy Milling (HEM). This research use the Completely Randomized Design (CRD) at dosage of (100; 141,42; 200; 282,82; 400)mg/20g body weight. The lungs were made into preparations by using the paraffin method and Hematoxylin Erlich-Eosin staining (HE). There were a significant difference (P<0,05) between control group and treatment groups on form of lung cells although no significant in lung weight

Histology of Spleen after Induction Nanoherbal Rhodomyrtus tomentosa Syafruddin Ilyas
International Journal of Ecophysiology Vol. 2 No. 1 (2020): International Journal of Ecophysiology
Publisher : Talenta Publisher

The study aim to know to effect of Nanoherbal Rhodomyrtus tomentosa (Haramonting) on spleen histology of Mus musculus. Haramonting in Indonesia as a new source of health-promoting compounds such as dietary fibers, essential fatty acids, and phenolic compounds because there are 19 phenolic compounds including stilbenes and ellagitannins as major components, followed by anthocyanins, flavonols, and gallic acid. Haramonting is made on a nanoscale using High Energy Milling (HEM). This research use the Completely Randomized Design (CRD) at dosage of (100; 141,42; 200; 282,82; 400)mg/20g body weight. The lungs were made into preparations by using the paraffin method and Hematoxylin Erlich-Eosin staining (HE). There were a significant difference (P<0,05) between control group and treatment groups on form of lung cells although no significant in lung weight

The Effect Of Giving Nano Herbal Biwa Leaf (Eriobotrya japonica Lindl.) Against Histological Description Of Kidney Rat That Induced By Alloxan Syafruddin Ilyas
International Journal of Ecophysiology Vol. 3 No. 1 (2021): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v3i1.10027

Diabetes mellitus is a metabolic disease characterized by hyperglycemia due to abnormal insulin secretion and insulin action. Uncontrolled diabetes mellitus will cause various organ complications, one of which is diabetic nephropathy or kidney failure. The aim of this study was to determine the effect of nano herbal of biwa leaves (Eriobotrya japonica) on the structure of gromerulus, renal necrosis, proximal tubular constriction, kidney weight and kidney discoloration. This study uses an analytic study with a true experimental design in male rats (Rattus norvegicus) consisting of five treatments with each of six replications. This study consisted of a negative control group that was only given ad-libitum feed, a positive control injected with alloxan, and two groups injected with alloxan and given a 250 mg/kg and 500 mg/kg biwa nanoherbal. It was concluded that the nanoherbal of biwa leaves is effective enough to reduce blood glucose levels and is safe for consumption by diabetics because it does not damage kidney cells.

The Effect of Giving Nanoherbal of Biwa (Eriobotrya japonica (Thunb.) Lindl. (Thunb.) Lindl.) Leaf on the Quality and Quantity of Spermatozoa And Microstructure in Diabetes Rat (Rattus norvegicus) Induced by Alloxan Syafruddin Ilyas
International Journal of Ecophysiology Vol. 3 No. 2 (2021): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v3i2.10101

One of causes in decreasing quantity and quality of spermatozoon is disease. Increased blood glucose levels can trigger demage of spermatogenesis in the testes, thereby reducing spermatozoa production. Biwa leaves (Eriobotrya japonica (Thunb.) Lindl.) contain triterpenes which are expected to overcome blood glucose levels and quantity of spermatozoa in the cauda epididymis. To investigate this problem, an experimental test of nano herbal of biwa leaves was carried out in a rat model (Rattus norvegicus) diabet. There are five treatments and six replications, it was found that the best dose of 500 mg/kg body weight could improve spermatogenesis so that the number of rat spermatozoa remained normal. It was concluded that nano herbal of biwa leaves can be used as an alternative drug to maintain fertility as seen from spermatogenesis and the number of spermatozoa. The result is analyzed by ANOVA test and further by Post-Hoc-Test (Duncan). The result show the significant differences (p<0,05) to quantity and quality of spermatozoon of adult white male mouse (Rattus norvegicus).

Immunohistochemistry examination to reveal the pathogenesis of Oral Squamous Cell Carcinoma Syafruddin Ilyas
International Journal of Ecophysiology Vol. 4 No. 1 (2022): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v4i1.11150

Oral mucosal cancer is a type of cancer that develops from the lining of the oral cavity (mucosa). The main risk factors are smoking and drinking alcohol. The pathogenesis of oral mucosal cancer involves various interrelated etiologies such as smoking and alcohol consumption, human papilloma virus (HPV), and patients who have undergone hemopoietic stem cell transplants (stem cell transplants). Meanwhile, it does not rule out the possibility of internal factors such as genetics. There are several types of oral mucosal cancer, but oral squamous cell carcinoma is the most common type of oral cancer and represents more than 90% of all head and neck cancers. Immunohistochemical examination of the Oral squamous cell carcinoma smear biopsy material which included examination of antibodies in the form of cytokeratin, CDT1, Ki-67, Geminin, Mcm2, γ-H2A/ histone family member X and Aurora-A, BCL-2, VEGF, p53, p63, p,73, Prb, c-erbB2 or HER2/neu, upregulation of telomerase (human telomerase reverse transcriptase; hTERT), loss of heterozygosity (Chromosome loci 3p, 8p, 9p, 4q, 11q, 13q, 17p), High-risk Human papillomavirus 16/18 (HR-HPV16 and 18), p16, Overexpression of EGFR, c-jun, c-fos, surviving (BIRC5), MMP-9, MMP9, TGF-, COX-1, and-2, and amplification of Cyclins D and E. Thus, paving the way for appropriate therapy.

Stem Cells: DNA Microarray Approach Syafruddin Ilyas
International Journal of Ecophysiology Vol. 4 No. 1 (2022): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v4i1.11151

In recent years, stem cell therapy has become a very promising and advanced scientific research topic. The development of treatment methods has evoked great expectations, not only researchers but also society due to its potency in cell-based therapy. Stem cells are unspecialized cells of the human body. They are able to differentiate into any cell of an organism and have the ability of self-renewal. Broadly speaking, the application of stem cells can be divided into two, namely: autotransplantation (donor and recipient are same person) and allotransplantation (donors and recipients are people who different). However, other applications namely xenotransplantation (donor and the recipient is the species that different) now it also becomes center of attention. Since it is challenging to isolate stem cells, molecular methods specifically the use of a DNA microarray, are one way to find stem cells. Microarrays have been applied in stem cell research to identify major features or expression signatures that define stem cells and characterize their differentiation programs toward specific lineages. This paper is a review focused on a discussion of the of the microarray technology and types of stem cell transplant.

Co-Authors . Suryati Ahri Maulida Bernard Bernard, Bernard Delyuzar, Delyuzar Eka Prasetiawan Emita Sabri Endang Sjamsudin Erlintan Sinaga Harry Agusnar Herti Folarida Hutajulu HG, Afifah Ayuni Hot Setiado Ibezaro Zega It Jamilah Jernih Nurani Hulu Kesuma Wardani Nanin Triana Nursal Nurul Amalia Sofyan Olivia Avriyanti Hanafiah Panal Sitorus Riza, Ahyar Ronald Pasaribu Rosmayati Rosmayati Saharman Gea Salomo Hutahaean Sri Wardani Ummi Kalsum Yasmeini Yazir Yetty Machrina Zulfiani Zulfi

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