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All Journal Indonesian Journal of Cardiology Sumatera Medical Journal Jurnal Prima Medika Sains JOURNAL LA MEDIHEALTICO Narra J Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Buletin Kedokteran dan Kesehatan Prima The Journal of Society Medicine (JSOCMED)
Mukhtar, Zulfikri
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Incidence of Bleeding Complications in Acute ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention Ferhat, Muhammad; Lubis, Anggia Chairuddin; Safri, Zainal; Mukhtar, Zulfikri; Hasan, Harris; Haykal, Teuku Bob; Siregar, Yasmine Fitrina; Andra, Cut Aryfa
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 7 No. 3 (2025): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v7i3.21143

Abstract

Background: This study aims to comprehensively describe the incidence, types, and associated risk factors of bleeding complications in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI), addressing a critical gap in the literature given the global burden of cardiovascular disease and the inherent bleeding risks of contemporary antithrombotic therapies. Methode: This retrospective cross-sectional study will investigate the incidence and types of bleeding complications, along with associated risk factors, in ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PPCI) at Adam Malik Hospital Medan, analyzing data from May 2022 to December 2024 through ethical review and statistical analysis using SPSS version 23. Result: Of 245 STEMI patients undergoing primary PCI, 42.9% experienced bleeding, predominantly minor (BARC 1 and 2, 94.2% combined), with significant associations observed between bleeding and lower hemoglobin, higher leukocyte and creatinine levels, higher TIMI score, Killip class 3 and 4, diabetes, use of maintenance heparin, and increased mortality (84.6% of all deaths occurred in bleeding patients), while hematuria and puncture site hematoma were the most common bleeding sources. Conclusion: This study found that 42.9% of 245 STEMI patients undergoing primary PCI experienced bleeding complications, predominantly minor (94.2%), with an average age of 55.22 years and a male majority. Keyword: Bleeding complications, Acute Coronary Syndrome (ACS), ST-Elevation Myocardial Infarction (STEMI), Primary Percutaneous Coronary Intervention (PPCI)
Factors influencing the participation of mothers with toddlers in posyandu activities in Kemenangan Tani Village, Medan Tuntungan District Mujahidin, Mujahidin; Wenti Anggraeni, Wenti; Daeli, Elisa Hotmauli Gratia; Sabri, Ihsan; Ivonne, Ivonne; Muchtar, Muhammad Arafat; Riskaldy, Riskaldy; Dewani , Yunita; Ferdinand, Sahna; Mukhtar, Zulfikri; Reza, Faisal
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.7442

Abstract

Posyandu is a type of community-based health effort (UKBM) which is managed and organized by, for, and with the community in the implementation of health development. Empowering the community to obtain essential health services, accelerating the reduction of maternal and child mortality. This study aims to determine the relationship between knowledge and characteristics of mothers under five with visits to posyandu activities in Kelurahan Kemenangan Tani. This research is an analytic survey with a cross-sectional approach. The population in this study were mothers of children under five at the Kelurahan Kemenangan Tani Posyandu. The sample in this study was 60 respondents with the determination of the number of samples using the slovin formula. The sampling technique used is proportional random sampling with inclusion and exclusion criteria. Data was collected through interviews using a questionnaire. This study used the chi-square statistical test (Confidance Interval (CI) 95%; = 0.05). Multivariate analysis using logistic regression. The results of this study indicate that there is a significant relationship between mother's knowledge and mother's characteristics with the visit of mothers under five in posyandu activities (p < 0.05). The dominant independent variable was education (p= 0.011; PR= 14,903, 95% CI = 1,872-118,660). The conclusion of this study is that there is a significant relationship between mother's knowledge and mother's characteristics with the visit of mothers under five in posyandu activities. The dominant independent variable is education.
The association between smoking behaviour and degenerative diseases Simarmata, Gracia Imanuela; Hartono, Hartono; Sihotang, Widya Yanti; Tobing, Andrico Napolin Lumban; Dharma, Surya; Mylano, Tri Adi; Setiawan, Deni; Willano, Almira; Novianti, Desi; Suwanto, Denny; Haryadi, Haryadi; Mukhtar, Zulfikri; Kunardi, Sidharta; Reza, Faisal
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 2 (2025): September
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i2.7756

Abstract

Degenerative diseases represent a leading global cause of death, imposing a substantial health burden, wherein behavioural factors such as smoking are posited to play a significant role. This study aimed to analyse the association between smoking behaviour and the incidence of various degenerative diseases through a systematic literature review. The methodology employed was a systematic literature review, with article searches conducted across Google Scholar, PubMed, and Scopus databases from May to June 2025. Inclusion criteria encompassed full-text articles in Indonesian or English, published between 2020 and 2025, focusing on the association between smoking and degenerative diseases (hypertension, diabetes, stroke, kidney failure, cancer). From 230 identified articles, 15 met the criteria and were analysed. The synthesis of results demonstrated a significant association between smoking behaviour and an increased risk of degenerative diseases. Active smokers exhibited a three-fold higher risk of hypertension (OR=3.445), a twelve-fold higher risk of type 2 diabetes mellitus (OR=12.747), and a greater risk of developing cancer (lung, breast, laryngeal), stroke, and chronic kidney disease (CKD). Exposure to secondhand smoke among passive smokers also increased the risk of breast cancer nearly fourfold (OR=3.778). Underlying mechanisms include oxidative damage, chronic inflammation, endothelial dysfunction, and metabolic dysregulation. It is concluded that smoking is a major modifiable risk factor for degenerative diseases. Strengthening tobacco control policies, intensive health education, and smoking cessation programmes are required as primary prevention strategies.
Co-Authors Akbar, Nizam Zikri Alexander, Rico Alfuadi, T. Rifki Mirza Amin, Mustafa M. Andra, Cut A. Andra, Cut Aryfa Ardini, Tengku Winda Daeli, Elisa Hotmauli Gratia DENI SETIAWAN Dewani , Yunita Djohan - Doni Firman Eyanoer, Putri C. faisal Reza Ferdinand, Sahna Ferhat, Muhammad Habib, Faisal Hartono Hartono Haryadi - Hasan, Harris Hasan, Harris Hasan, Refli Haykal, T. Bob irza Haicha Pratama Ivonne, Ivonne Jayanti, Herlina Karo, Kartika br Ketaren, Andre Pasha Ketaren, Andre Pasha Khaidirman, Sophia Khairina Kunardi, Sidharta Lubis, Anggia Chairuddin Lubis, Hilfan Ade Putra Muchtar, Muhammad Arafat Mujahidin Mujahidin Mylano, Tri Adi Nasution, Chairul Radjab Nasution, Syamsul Arifin Novianti, Desi Purba, Arna Fransisca Millyanti Rahimi, Armon Rambe, Aldy S. Raynaldo, Abdul Halim Riskaldy, Riskaldy Rudi Chandra Rusda, Muhammad Ryanti, Dina Sabri, Ihsan Safri, Zainal San, Kon Sarastri, Yuke Sembiring, Rosita Simarmata, Gracia Imanuela Sitepu, Andika Suhartina Suhartina, Suhartina Surya Dharma Suwanto, Denny Syahrian, Muhammad Faridz Tamba, Ratna Mariana Taufik Sungkar, Taufik Teuku Bob Haykal Tobing, Andrico Napolin Lumban Todung Donald Aposan Silalahi Wenti Anggraeni, Wenti Widya Yanti Sihotang Willano, Almira Yasmine Fitrina Siregar