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All Journal Folia Medica Indonesiana Window of Health : Jurnal Kesehatan Jurnal Respirasi (JR) UMI Medical Journal Green Medical Journal Jurnal EduHealth International Journal of Health and Pharmaceutical (IJHP) jpki
Wiriansya, Edward Pandu
Universitas Muslim Indonesia
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary Other

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Effects of E-Cigarette Vapor Smoke on Pulmonary Alveoli in Rattus norvegicus Lungs Edward Pandu Wiriansya; Dewi Rahman; Muhammad Naufal Zuhair; Syamsu Rijal; Dzul Ikram; Utomo Andi Pangnguriseng
Jurnal Respirasi Vol. 9 No. 3 (2023): September 2023
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v9-I.3.2023.200-205

Abstract

Introduction: Vapor is considered a safer alternative to tobacco cigarettes because the high nicotine content is less. However, vapor still contains substances that are classified as toxic to humans. Short-term exposure to vapors from liquids can induce an inflammatory response in the lungs and cause oxidative stress. This study aimed to determine the effects of e-cigarette vapor smoke on pulmonary alveoli in Rattus norvegicus lungs. Methods: This was an experimental study on 32 adult male Rattus norvegicus rats. They were divided into two groups exposed to nicotine-containing vapor smoke two times a day for one and three months, respectively, and one group as control. After vapor exposure, the lung tissues of the rats were taken and then subjected to histopathological examination under a microscope. Results: After exposure for one month, epithelial and endothelial cells degenerated, characterized by a decrease in collagen and elastin fibers in the extracellular matrix. For three months, there were changes, the alveolar membrane had no nucleus, the surrounding endothelial cells were not visible due to damage to the extracellular matrix, the alveolar lumen had widened, causing edema in the lumen of the alveoli, and the alveoli wall was destroyed. Therefore, the connection between the alveoli was stretched. Conclusion: This study found that short-term exposure to nicotine vapor causes damage to the alveoli membrane.
Characteristics Of Dyspepsia Patients Undergoing Endoscopy At Ibnu Sina Hospital Makassar Muh Anugrah Ramadhan; Prema Hapsari Hidayati; Rachmat Faisal Syamsu; Asrini Safitri; Edward Pandu Wiriansya; Rahmawati, Rahmawati; Andi Muhammad Luthfi Parewangi
Jurnal EduHealth Vol. 15 No. 02 (2024): Jurnal eduHealt, Edition April - June , 2024
Publisher : Sean Institute

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Abstract

Background: According to the World Health Organization (WHO) that Indonesia ranks 3rd with the highest number of dyspepsia sufferers after America and England with 450 dyspepsia sufferers. According to the 2017 health data profile, dyspepsia is included in the top ten inpatient diseases.Objective: To determine the characteristics of dyspepsia patients undergoing endoscopy at the Ibnu Sina Hospital Makassar. Research methods: The research design used was descriptive research with a cross sectional approach using secondary data at the medical record installation at Ibnu Sina Hospital, Makassar. Research result: Of the 85 samples in the study, most were in the middle age of 45-54 years, namely 58 patients (68.2%), in the area of ​​origin the highest was the province of South Sulawesi, namely 80 patients (94%), the most gender was female, namely 38 patients (44.7%), the highest complaints were complaints (cough, tightness, and chest pain) namely 85 patients (100%), the largest laboratory results were laboratory results (hemoglobin, urea, SGOT and SGPT) namely 80 patients (80% ), the most common indication for endoscopy was chronic dyspepsia, namely 72 patients (84.7%), the most clinical diagnosis was functional dyspepsia, namely 32 patients (37%), the most endoscopy diagnosis was erosive gastritis, namely 38 patients (100%). Conclusion: Characteristics of patients with dyspepsia symptoms undergoing endoscopy at Ibn Sina Hospital Makassar, namely middle age, female sex, complaints of heartburn, endoscopy indications for chronic dyspepsia, clinical diagnosis of functional dyspepsia, and endoscopy diagnosis of erosive gastritis.  
Tuberculosis Infection In Women Fitrah Ahmad, Izhar; Pandu Wiriansya, Edward; Puspa Ratu, Andi; Kasim, Sharen
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 1 (2025): February 2025 (Indonesia - Turkey - Malaysia - Australia - Iran)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i1.406

Abstract

The increasing number of deaths due to tuberculosis has triggered the national tuberculosis control program to continue to intensify, accelerate, extend and innovate the program.7A holistic approach must be taken in order to improve tuberculosis control and identify various risk factors associated with tuberculosis infection. The Global Tuberculosis Report 2018 reported that 90% of tuberculosis sufferers are adults and 10% are children (<15 years). Figure 1 shows tuberculosis sufferers worldwide, 64% are men and 36% are women with a ratio of 2:1. In Indonesia, data also shows that tuberculosis is more common in men than women. The high prevalence in men shows that the level of men accessing tuberculosis services is higher than women. Differences in social roles between men and women can also affect risk factors for access to health services. In women, access to tuberculosis treatment and prevention services is more difficult than in men. This is because family members do not want to pay for women's health services. Women's health in the family is considered less important than male family members. Tuberculosis problems also occur in vulnerable populations, namely pregnant women and women with tuberculosis-HIV. A fairly high mortality rate occurs in women with tuberculosis-HIV. In pregnant women, transmission of tuberculosis germs to the fetus occurs, so that the fetus can have latent tuberculosis. Understanding tuberculosis disease in women can help the target of eliminating tuberculosis by 2030. Gender equality and active participation of women in the planning, implementation, and health care processes can be an effective way to overcome the problems of difficulty in accessing tuberculosis services, stigma and discrimination, and various existing barriers.
Co-Authors Abdi, Dian Amelia Agung Dirgantara Ahmad Fahd Alifian Ainun Andi Muhammad Luthfi Parewangi Andi Sitti Fahirah Andi Tenri Sanna Andi Tiara Salengke Adam Anggita, Dwi Anna Sari Dewi Arina Fathiyyah Armanto Makmun Arni Isnaini Arfah Asrini Safitri Asrini Safitri Asrini Safitri Dewi Rahman Dian Amelia Abdi Dinda Permatasari, Dinda Dzul Ikram Eny Arlini Wello Febie Irsandy Fendy Dwimartyono Fitrah Ahmad, Izhar Irawaty Djaharuddin Kasim, Sharen Laksmi Wulandari Lisa Yuniaty M. Hamsah Muh Anugrah Ramadhan Muhamad Ilhamsyah Dandung Muhammad Mursyid Muhammad Naufal Zuhair Muhammad Reza Cesarian Noor, Andi Nasrudin Andi Mappaware Noor, Andi Muhammad Reza Cesaria Nurfachanti Fattah Prema Hapsari Hidayati Puspa Ratu, Andi Rachmat Faisal Syamsu Rachmat Faisal Syamsu Rahman, Titin Suhartina Rahmawati Rahmawati Rahmawati, Rahmawati Rasfayanah Rasfayanah Ratu, Andi Puspa Ratu, Puspa Santriani Hadi Shofiyah Latief Siti Nurisyah Sri Wahyu Sri Wahyuni Gayatri Susilo, Wawan Syamsu Rijal Syamsu Rijal Utomo Andi Pangnguriseng Yusriani Mangarengi Zulfah Midah Zulfahmidah Zulfitriani Murfat Zulfiyah Surdam