Article Per Year (5 Year)
p-Index From 2021 - 2026
5.749
P-Index
This Author published in this journals
All Journal Jurnal Pendidikan Sosiologi dan Humaniora Paduraksa : Jurnal Teknik Sipil Universitas Warmadewa Jurnal IPTEK Jurnal Manajemen AGREGAT Jurnal Teknik Industri: Jurnal Keilmuan dan Aplikasi Teknik Industri Jurnal Aplikasi Teknik Sipil Prosiding Seminar Nasional Sains dan Teknologi Terapan Reka Buana : Jurnal Ilmiah Teknik Sipil dan Teknik Kimia Jurnal Rekayasa Konstruksi Mekanika Sipil Jurnal Riset Inspirasi Manajemen dan Kewirausahaan axial : jurnal rekayasa dan manajemen konstruksi JURNAL FARMASIMED (JFM) Jurnal Pelayanan dan Pengabdian Masyarakat (Pamas) Civilla : Jurnal Teknik Sipil Universitas Islam Lamongan Jurnal Riset Bisnis dan Manajemen Indonesian Journal of Pharmaceutical and Clinical Research Jurnal Abdi Insani DEDIKASI PKM Bharanomics Jurnal Pengabdian kepada Masyarakat Jurnal Teknologi dan Manajemen Jurnal Teknik Sipil CITIZEN: Jurnal Ilmiah Mulitidisiplin Indonesia Penamas: Journal of Community Service Jurnal Ilmiah Akuntansi dan Keuangan (JIAKu) Jurnal Kreativitas dan Inovasi (Jurnal Kreanova) Jurnal Pariwisata, Bisnis Digital dan Manajemen AMMA : Jurnal Pengabdian Masyarakat International Journal of Financial and Investment Studies Journal of Civil Engineering, Planning, and Design (JCEPD) JER Datum: Journal of Geodesy and Geomatics
Dewi Pertiwi
Institut Teknologi Adhi Tama Surabaya
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Transportation Other

Published : 51 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 51 Documents
Search

 2   3   4   5   6 
Effect of Tocotrienol Rich Fraction (TRF) Administration on Blood Glucose and Cholesterol in Streptozotocin Induced and High Fat Diet Rats Simangunsong, Irene; Pertiwi, Dewi; Dalimunthe, Aminah; Asfianti, Vivi
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/139epr61

Abstract

Diabetes mellitus (DM) is a chronic metabolic disorder with a continuously increasing global prevalence and remains a major health problem, characterized by hyperglycemia and dyslipidemia, including elevated Low Density Lipoprotein (LDL) and decreased High Density Lipoprotein (HDL) levels. This study aimed to evaluate the effect of tocotrienol rich fraction administration on blood glucose levels and lipid profile in rats induced with streptozotocin and a high fat diet. The study used 24 white rats divided into six groups: a negative control group, a positive control group treated with glibenclamide, and four treatment groups receiving tocotrienol rich fraction at doses of 50, 100, 200, and 400 mg/kg body weight. The measured parameters included blood glucose, HDL, and LDL levels. The results show that tocotrienol rich fraction significantly reduces blood glucose levels and improves the lipid profile compared to the negative control group. The highest dose demonstrates the most optimal effect and approaches that of the positive control. Tocotrienol rich fraction increases HDL levels and decreases LDL levels in a dose dependent manner. These findings indicate that tocotrienol rich fraction significantly lowers blood glucose levels and improves lipid profile in streptozotocin induced and high fat diet rats in a dose dependent manner. Therefore, tocotrienol rich fraction has potential as an alternative therapeutic agent for diabetes mellitus with dyslipidemia.
Co-Authors Abdi Hakiki Achmad Jaelani Agusdini, Theresia Maria Ahmad Wahyu Setiawan Alifa, Asyika Nur Aminah Dalimunthe Apriyanto, Arie Fauzi Ari Gandhi Sabban Arifin, Moch.Ali Arintha Indah Dwi Syafiarti Armijon . Arsid Asfianti, Vivi Awalya, Rahmannisa Syifa Bantot Sutriono, Bantot Boedi Wibowo Budi P, Atik Christin Mardiana Chriswanto, Evelyn Jennis Clarence, Johann Dewi Astuti Diah Listyaningsih Dita Kamarul Fitriyah Dumilah, Jelita Retno Eka Susanti Eka Susanti Eka susanti Eko Rahmadi Endang Kasiati Eugene, Rebecca Farchan, Muchamad FAUZI, HARIS Felicia Tria N Ferdian Adhitia Ferdian Adhitia Ananda Gemiartha, Celine Morgan Godwin, Danniel Tristano L. Gunawan, Marvel Gustiaranti, Audrey Agdennia Hadap, Billy Mathew Hakiki, Abdi Hapsari, Rachel Cintantya Hayat, Nurul Hendrik Kusuma Atmaja Heri Istiono Ibram Bramasta Arifin Ihsanul Hafiz Indra Komara, Indra Indra Sari, Hastuti Istiono, Heri Jaka Propika Jaka Propika Jenny Caroline Kania Laelawati Kartiko, Andi Susilo Katili, Kevin Kempa, Sesilya Khoir, Fatihul Kurnia Hadi P Kurnia Hadi Putra Kurniawan, Abraham Ivan Kurniawan, Mochammad Rizky Kusumaningrum, Dewi Mahendra Nata, Eric Vianto Maulana Maulana, Maulana Melinda, Graceline Michella Beatrix Mila Kusuma Wardani Muhammad Risky Mahensa Muliadji, Adelia MULYADI Natalia, Vicencia Giovenna Nur Laelatul Fadiyah Nurul Rochmah Ori Feizal Qirom Pratama, Eric Prayogo, Nathania Cherryl Qirom, Ori Feizal Rahardjo, Richie Farandy Rahmalia Salma Rahmasari, Anggraeni Ratih Indriyani Rio Andri Ansyah Risky Murinda Risqy K, Rachmad Ryanditama Pramudya Santoso, Nicholas Adi Sekartadji, Ratih Setiadiwiria, Mahersya Christiani Simangunsong, Irene Siti Choiriyah Sofian, Merviona Sudarsono, Jethson Edbert Sugianto, Kenneth Suprapto, Widjojo Teguh, Ansella Jovita Theresia Maria CA Theresia Maria CA Theresia MCA Triaswati MN Triaswati Triaswati Umbu Miron Wahyu Setiawan, Ahmad Wijaya, Feysya Sandrina Wiranata, Destya Wongso, Samuel Alfred Yanisfa Septiarsilia