Article Per Year (5 Year)
p-Index From 2020 - 2025
4.245
P-Index
This Author published in this journals
All Journal Jurnal Kedokteran Syiah Kuala Berkala Ilmu Kesehatan Kulit dan Kelamin Folia Medica Indonesiana Transformasi: Jurnal Pengabdian Masyarakat Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) Jurnal Ilmiah Universitas Batanghari Jambi Journal Of Vocational Health Studies Jurnal Keperawatan Padjadjaran Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Medik Veteriner Jurnal Ilmu Kefarmasian Indonesia J-Dinamika: Jurnal Pengabdian Kepada Masyarakat Biomolecular and Health Science Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Jurnal Layanan Masyarakat (Journal of Public Service) Jurnal Psikiatri Surabaya (Surabaya Psychiatry Journal) JOURNAL OF COMMUNITY MEDICINE AND PUBLIC HEALTH RESEARCH Indian Journal of Forensic Medicine & Toxicology International Journal of Social Service and Research KESANS : International Journal of Health and Science
Indiastuti, Danti Nur
Department Of Anatomy, Histology, And Pharmacology, Faculty Of Medicine, Universitas Airlangga, Surabaya, Indonesia.
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

Published : 28 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search
Journal : JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga

 1 
Resistance Patterns of Escherichia coli and Klebsiella pneumoniae Bacteria Against Amikacin, Ceftazidime, Meropenem, Nitrofurantoin Antibiotics in Elderly Patients with UTI in RSUD Dr. Soetomo Herdiyanti Herdiyanti; Lindawati Alimsardjono; Danti Nur Indiastuti
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 10 No. 1 (2019): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (642.783 KB) | DOI: 10.20473/juxta.V10I12019.20-24

Abstract

Introduction: Urinary tract infection (UTI) is an infection that involves the urinary tract, including the urethra, bladder, ureter, and kidneys. UTI is caused by microorganisms that breed in the urinary tract which are supposed to be free of microorganisms. Two bacterias that cause UTI in general are Escherichia coli and Klebsiella pneumoniae. UTI can occur at any age but generally occurs in the elderly. UTI caused by gram-negative bacteria can be killed with several examples of antibiotics namely amikacin, ceftazidime, meropenem and nitrofurantoin. These antibiotics found resistance to the bacteria that cause the UTI. This research is to determine the resistance patterns of Escherichia coli and Klebsiella pneumoniae bacteria against amikacin, ceftazidime, meropenem, nitrofurantoin antibiotics in elderly patients with UTI in Dr. Soetomo Surabaya January-June 2017 period.Methods: A descriptive retrospective study in accordance with the logbook data of Clinical Microbiology Installation at Dr. RSUD. Soetomo Surabaya. Data from this study were taken from all populations that met the inclusion criteria. The results are presented by tables. Results: There are 163 elderly patient data which diagnosed with urinary tract infection. Escherichia coli resistance pattern against ceftazidime (75.6%), nitrofurantoin (12.6%) and meropenem (2.4%). Meanwhile, Klebsiella pneumoniae against ceftazidime (72.2%), nitrofurantoin (55.6%), meropenem (11.1%) and amikacin (2.8%). Conclusion: There were resistance number of Escherichia coli and Klebsiella pneumoniae bacteria against antibiotics amikacin, ceftazidime, meropenem, nitrofurantoin in elderly patients with UTI.
Effect of Carrots (Daucus carota L.) on Gastric Histopathology of Piroxicam-Induced Mice as a Peptic Ulcer Prevention Jennifer Susanto; Danti Nur Indiastuti; Gondo Mastutik
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 13 No. 2 (2022): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V13I22022.88-92

Abstract

Highlights:1. Carrots (Daucus carota L.) can reduce the side effects of non-steroidal anti-inflammatory drugs (NSAIDs) due to its gastroprotective components.2. Histopathological studies of the gastric inflammation signs showed that carrots can prevent NSAID-induced peptic ulcers. AbstractIntroduction: Non-steroidal anti-inflammatory drugs (NSAIDs) consumption contributes significantly to gastrointestinal morbidity, including peptic ulcers. NSAIDs cause gastric mucosal damage by inhibiting PGE2 and PGI2 secretion, increasing HCl secretion, and also causing local irritation and neutrophil adhesion. Flavonoids and chlorogenic acid are gastroprotective agents found in carrots (Daucus carota L.). Therefore, this study aimed to validate the effect of carrots on gastric histopathology of piroxicam-induced mice.Methods: This was an experimental study using a post-test-only control group design. 35 mice were divided into 5 groups and were allowed to adapt for 1 week. The negative control group received 0.25 mL aqua dest, while the positive control group received 0.104 mg famotidine. Group A, B, and C received carrot extract with each dosage was 200 mg/kgBW, 300 mg/kgBW, and 400 mg/kgBW. The mice were induced 2 hours later with 0.052 mg piroxicam. The treatments lasted 14 days. Each stomach was taken and examined on the 15th day. Afterward, histopathological preparations were made.Results: The results of the histopathological signs of inflammation using the Kruskal-Wallis method showed p = 0.000, indicating that there was an effect of the carrot extract in preventing the inflammation on the gastric histopathology (p < 0.05).Conclusion: In conclusion, this study confirmed that carrot extract is more effective in avoiding peptic ulcers due to NSAID consumption.
Antibacterial Effects of Basil (Ocimum sanctum) Leaf Extract in Combination with Meropenem against Extended Spectrum Beta-Lactamase (ESBL) Producing Klebsiella pneumoniae Lifindra, Billy Yanssen; Wiqoyah, Nurul; Indiastuti, Danti Nur
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 15 No. 2 (2024): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V15I22024.88-93

Abstract

Highlights: Ocimum sanctum leaf extract does not significantly increase its antibacterial effects when combined with meropenem against ESBL-producing K. pneumoniae. Ocimum sanctum leaf extract has different antibacterial effects depending on geological and environmental factors.   Abstract Introduction: Antibiotic usage for bacterial infections causes antibiotic resistance in bacteria. One is extended-spectrum beta-lactamase (ESBL), which produces Klebsiella pneumoniae, a pathogen responsible for increased antibiotic resistance. Basil (Ocimum sanctum) is a candidate for combination therapy. It has been proven to have antibacterial effects. However, its combination with antibiotics is rarely researched. This study evaluated the antibacterial effects of O. sanctum leaf extract and meropenem combination against ESBL-producing K. pneumoniae. Methods: This study used the disk diffusion method. The extract was tested for each experiment at 6%, 4%, 2%, 1%, and 0.5% concentration. The research was divided into two experiments to evaluate the antibacterial effects of O. sanctum leaf extract (n=18) and its combination with meropenem against ESBL-producing K. pneumoniae (n=18). The data was analyzed using the International Business Machines Corporation (IBM) Statistical Package for the Social Sciences (SPSS) version 26.0 for Windows. A probability p<0.050 was considered significant. Results: The first experiment showed that the extract had the largest antibacterial effect at 0.5% concentration (n=18, p=0.007). Meanwhile, the second experiment showed that the combination of the extract and meropenem did not have significant antibacterial effects (n=18, p=0.597). Conclusion: Ocimum sanctum leaf extract has viable antibacterial effects, but its combination with Meropenem does not significantly improve its antibacterial effects against Extended Spectrum Beta-Lactamase (ESBL) producing K. pneumoniae.
The Role of Vitamin C Supplementation in Preventing Severity Progression in Mild and Moderate COVID-19 Patients at Universitas Airlangga Hospital Arifandi, Yoga Akbar; Rosyid, Alfian Nur; Indiastuti, Danti Nur; Effendi, Wiwin Is
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 16 No. 1 (2025): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V16I12025.63-69

Abstract

Highlights: The administration of different dosages of vitamin C significantly yields different outcomes in preventing the progression of disease severity. Most patients with mild and moderate coronavirus disease (COVID-19) did not demonstrate an escalation in disease severity.   Abstract Introduction: Coronavirus disease (COVID-19) is an infectious disease that increases pro-oxidant elements and decreases antioxidants. Vitamin C functions as a potent antioxidant in humans due to its electron-donating properties.  This study aimed to explain the impact of three distinct vitamin C supplementation dosages in preventing disease severity progression among mild and moderate COVID-19 patients. Methods: This retrospective study used secondary data from 100 medical records (n=100). The subjects were classified into three categories based on the vitamin C dosage. The data were analyzed using the International Business Machines Corporation (IBM) Statistical Package for Social Sciences (SPSS) version 26.0 for Windows. Results: Most of mild and moderate COVID-19 patients (78%) did not experience increased disease severity. Vitamin C supplementation significantly demonstrated a different outcome in preventing disease severity progression among the three groups (p=0.018). However, it did not significantly show any difference in reducing the duration of hospital stay (p=0.680). Conclusion: The impact of vitamin C supplementation on COVID-19 severity appeared to vary depending on the dosage administered. However, it did not affect the duration of the hospital stay.
Co-Authors Abdurrahman Hasyim Asy’ari Adila, Vatine Agung Dwi Wahyu Widodo Akbar Kurniawan, Mohammad Alarik L., Albertus Alimsardjono, Lindawati Anastassya Yuniar Setyo Putri Annette d’Arqom, Annette Ardana, Arin Aurilia Arifa Mustika Arifandi, Yoga Akbar Arnapi, Almara Diva Puteri Arthur Pohan Kawilarang Bajuber, Qonita Bakhtiar, Arief Desi Rahmah Sari Dewangga Sakti Satria Kinasih Dewi Tri Utami, Mahrumi Dinda Divamillenia Dini Indah Berlianti Doman, Zahras Azimuth Edward Kusuma Effendi, Wiwin Is Ekiyanti, Khisma Farhan Nurdiansyah Fatimah, Nurmawati Gabriel Pedro Mudjianto Gondo Mastutik Grawira Drana Putra Respati Hamzah Hamzah Hamzah Rafly Rahman Hasanatuluddhiyah, Nurina Herdiyanti Herdiyanti Indri Safitri Mukono, Indri Safitri Jennifer Susanto Jihan Nur Fauziah Jonathan Christianto Sutadji Junaidah Yusof Kusuma Eko Purwantari Lifindra, Billy Yanssen Linda Astari, Linda Maftuchah Maftuchah Mariska Nuriana Mhd Zamal Nasution Mia Ratwita Andarsini Muhammad Hafizh Muhammad Raihan Habibi Nabil Alfin Juhri Nadia Mardiana Hudan Natasya Ariesta Selyardi Putri NOOR CHOLIES Nurina Hasanatuludhhiyah Nurul Wiqoyah, Nurul Octaviana Galuh Pratiwi Pangkerego, Margareth Ayu Caroline Pascalis Fabian Peter Asa Prasetyo, Hersati Purwanta, Marijam Puteri, Fira Adilah Putu Agus Arsana, I Qorib, Mohammad Fathul Rebekah Setiabudi, Rebekah Resti Yudhawati Rezi Ramawan Melbiarta Rezy Ramawan Melbiarta Rosyid, Alfian Nur Rusuldi, Reyna Cesariyani R. Savitri, Natasha Hana Shaohong Lai Shofiuddin Al Mufid Sri Purwaningsih Sri Purwaningsih Sri Ratna Dwiningshih Trisnawati Trisnawati Trisniartami Setyaningrum Wahyunitasari, Manik Retno Wibowo, Idznika Nurannisa Wiwin Retnowati Yuani Setiawati Zamal Nasution