Article Per Year (5 Year)
p-Index From 2021 - 2026
2.567
P-Index
This Author published in this journals
All Journal JURNAL PENDIDIKAN TAMBUSAI Jurnal Kesehatan Tambusai Jurnal Buana Farma Proceedings of the International Conference on Nursing and Health Sciences JIFI (Jurnal Ilmiah Farmasi Imelda) Duta Pharma Journal Proceeding of International Conference Health, Science And Technology (ICOHETECH) International Journal of Health, Engineering and Technology Majalah Cendekia Mengabdi Inovasi Jurnal Pengabdian Masyarakat (IJPM)
Septian Maulid Wicahyo
Program Studi Farmasi, Fakultas Ilmu Kesehatan, Universitas Duta Bangsa Surakarta, 57552, Jawa Tengah, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

Published : 18 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : Duta Pharma Journal

 1 
ANTIHYPERGLYCEMIC ACTIVITY, IMPROVING ENZIMATIC ANTIOXIDANT ACTIVITY OF ETHYL ACETATE FRACTION FROM KERSEN LEAVES (Muntingia calabura) ON INDUCED STREPTOZOTOSIN-NICOTINAMIDE RAT Wicahyo, Septian Maulid; Pratama, Kharisma Jayak
Duta Pharma Journal Vol. 4 No. 1 (2024): DUTA PHARMA JOURNAL
Publisher : Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/djp.v4i1.3811

Abstract

Balance blood glucose concentration and antioxidant activity are keys to prevent Diabetes Melitus and its complications. Kersen leaves (Muntingia calabura) a plant that have empirical usage for reducing glucose blood that can do both. Purposes of this study were for observing ethyl acetate fraction from kersen leaves effects in reducing blood glucose, improving enzim antioxidant SOD and GPx activity, reducing MDA concentration and β cell regeneration. Forty two Wistar male white rats of 8 weeks with weight 150-250 g were made diabetes with streptozotosin-nicotinamide and randomly divided into 7 groups. Group I as normal rats, group II diabetic rats, group III diabetic with glibenclamid treatment, group IV and V diabetic rat treated by ethil acetate fraction 250 dan 350 mg/kg BW respectively. treatment had done orally once a day within 18 days. Blood glucose was measured on the 1st, 4th, 11th and 18th day. Ethyl acetate fractions significantly decreased blood glucose concentration, improved SOD and GPx activity, reduced MDA concentration and regenerated pancreatic β-cell also occured. In conclusion, ethyl acetate fraction have antihyperglycemic activity, ameliorates enzimatic antioxidant activity and can induce β cell regeneration.
FORMULASI SEDIAAN GEL EKSTRAK ETANOL DAUN KEMANGI (Ocimum sanctum L.) DENGAN AMYLUM MANIHOT SEBAGAI GELLING AGENT Wicahyo, Septian Maulid; Fauzi Rifqi Pramita
Duta Pharma Journal Vol. 4 No. 1 (2024): DUTA PHARMA JOURNAL
Publisher : Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Basil leaves (Ocimum sanctum L.) contain bioactive compounds such as flavonoids, tannins, and saponins that have the potential as antibacterials and antioxidants. This study aims to formulate a gel preparation of basil leaf ethanol extract with manihot starch as a gel-forming agent, and to evaluate the physical characteristics and stability of the gel. The results showed that the formula with a concentration of 3% manihot starch gave optimal results in viscosity, pH, and gel spreadability. Stability tests showed that the gel remained stable during 28 days of storage at room temperature. This study proves the potential use of manihot starch as a natural alternative in gel formulation.
Co-Authors Anna Fitriawati Apriliawan, Hidayah Artini, Kusumaningtyas Artini, Kusumaningtyas Siwi Bagas Ardiyantoro Danang Raharjo Erikania, Susanti Fadilla, Fitri Hansa Fauzi Rifqi Pramita Fitriani, Noviana hanif fathur rohman, muhammad Listyani, Tiara Ajeng Nadzifah, Ifah Nur Hikmah, Siti Permata, Bangkit Riska Pratama, Kharisma Jayak Qurrota'Ain, Rusyda Rahmatillah, Annie rani, fahrenza meta Ratna Safitri Shinta Putri Rahmawati tri Mastuti, eni uswatun hasanah, alfiana Voen-Na, Cut Dara Wardani, Tatiana Siska