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Characteristics of Cutaneous Lupus Erythematosus Patients in Dermatology and Venereology Outpatient Clinic Suryawati, Nyoman; Praharsini, I Gusti Ayu Agung; Elis Indira, I Gusti Ayu Agung; Darmaputra, I Gusti Nyoman
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 3 (2025): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikkk.V37.3.2025.153-162

Abstract

Background: Cutaneous lupus erythematosus (CLE) is a specific skin manifestation of lupus erythematosus. This condition can be accompanied by systemic involvement that affect patient therapy and prognosis. The characteristics of CLE patients in Indonesia have not been widely reported. This study aims to determine the prevalence and characteristics of CLE patients at Dermatology and Venereology Outpatient Clinic of Allergy and Immunology Division at Ngoerah Hospital. Methods: This research used descriptive analysis with a cross-sectional design and total sampling method. Result: The total number of patients was 34, with prevalence of 6.7 cases per 1,000 patients. The majority of patients were female (85.3%), Balinese ethnicity (70.6%), unemployed (53%), with a high school/vocational high school education (56%), and risk factors of sun exposure (80.0%). Most patients had no family history of Lupus erythematosus (LE) (65.7%). The most frequent skin manifestation was chronic type CLE (28.6%). Based on The European League Against Rheumatism/American College of Rheumatology (EULAR/ACR) score, 27 patients (77.1%) met Systemic lupus erythematosus (SLE) criteria. Cutaneous Lupus Erythematosus Disease Area and Severity Index (CLASI) activity, damage, and Mexican Systemic Lupus Erythematosus Disease Activity (MEX-SLEDAI) scores were 3.35±4.52, 0.88±1.96, and 7.5±5.09. Systemic therapy included methylprednisolone (47%) and hydroxychloroquine (35.2%), topical treatment included high to very high-potency steroids (67.6%), and sunscreen (14.7%). Response therapy was generally good in 68.6% of patients. Conclusion: The most common type of CLE is chronic cutaneous lupus erythematosus. Most patients improved, with the majority using systemic methylprednisolone and topical high-potency corticosteroids. Oral treatment responses tend to be good.
Co-Authors Agiel Fahlevie Choirunanda Anak Agung Gde Putra Wiraguna Anak Agung Gde Putra Wiraguna Anak Agung Gde Putra Wiraguna Anak Agung Indah Jayanthi Batan, Putu Nila Wardhani Cita Rosita Sigit Prakoeswa Daarshawnee Segar Darmaputra, I Gusti Nyoman Devi, Putu Akopita Elice Wijaya Elis Indira, I Gusti Ayu Agung Febrina D Pratiwi Hasri Dewi Henny Wijaya Hosea, Felicia Emiliana I Dewa Made Rendy Sanjaya I Gde Nengah Adhilaksman I Gde Nengah Adhilaksman Sunyamurti Wirawan I Gede Raditya Narayana I Gusti Ayu Agung Dwi Karmila I Gusti Ayu Agung Elis Indira I Gusti Nyoman Darmaputra I Komang Arimbawa IGNA Wisnu Kresnan Dana Indira, I Gusti Ayu Agung Elis Jihan Prani Wibowo Ketut Kwartantaya Winaya Khathreen, Corry Laksmi, I Gusti Ayu Agung Mini Luh Gede Melia Puspita Sari Luh Made Mas Rusyati Luh Putu Sustiana Kartika Sari Made Wardhana Martalova AJ, Adelia Marvin Giantoro Muhammad Hidayatullah Syukri Ni Kadek Setyawati, Ni Kadek Ni Kadek Yunita Arsita Dewi Ni Luh Putu Ratih Vibriyanti Karna Ni Made Adi Tarini Ni Made Dwi Puspawati Ni Nengah Dwi Fatmawati Ni Wayan Evita Pradnya Dharmesti Nyoman Suryawati Nyoman Yoga Maya Pramita Nyoman Yoga Maya Pramita Pramita, I Gusti Ayu Sattwika Prima Saraswati Sanjiwani Sudarsa Putu Nanda Tediantini Putu Nila Wardhani Batan Putu Nila Wardhani Batan Putu Raisha Vishkariana Dewi Ratih Purnamasari Nukana Ricky Fernando Maharis Rikcy Fernando Maharis Riyana Noor Oktaviyanti Salonika Sutiawan, Indry Setyono, Alfred Stefani Nurhadi Tiara Evangelista Triatmakusuma, Yogi Wicaksono, Rafael Lilik Winaya, Ketut Kwartantaya Wisnu Triadi Nugroho