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All Journal PREPOTIF : Jurnal Kesehatan Masyarakat Al-Iqra Medical Journal : Jurnal Berkala Ilmiah Kedokteran Jurnal Kesehatan Tambusai Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE) Jurnal Pengabdian Masyarakat Nusantara Jurnal Abdimas Indonesia Journal of Community Service and Society Empowerment ALMURTADO: Journal of Social Innovation and Community Service Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Sim, Alfred Sutrisno
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Associations Between Muscle Strength, Glomerular Filtration Rate, And Fall Risk: Insights From The Morse Fall Scale Sim, Alfred Sutrisno; Santoso, Alexander Halim; Teguh, Stanislas Kotska Marvel Mayello; Pranata, Catherine Christiana; Soeltanong, Dianova
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 5 No. 1 (2025): Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v5i1.6054

Abstract

Falls among older adults and individuals with chronic conditions pose a major public health concern, leading to injuries, reduced quality of life, and increased healthcare costs. Identifying modifiable risk factors is crucial for prevention. Muscle strength, particularly in the lower extremities, and renal function, measured by glomerular filtration rate (GFR), are potential predictors of fall risk. Sarcopenia and chronic kidney disease (CKD) exacerbate muscle weakness, impairing balance and mobility. While the Morse Fall Scale (MFS) assesses clinical and environmental risks, it lacks physiological measures like muscle strength and renal function. This study aims to bridge this gap by examining associations between muscle strength, GFR, and fall risk, enhancing fall risk assessments and contributing to a more comprehensive understanding of fall prevention. This cross-sectional study at Bina Bakti Nursing Home was done in 2024 examined muscle strength, GFR, and fall risk in 93 elderly (≥60 years). Participants provided consent; those with incomplete data were excluded. Partial correlation analysis showed strong right-left grip strength correlation (p < 0.001) but no significant associations with Morse Fall Scale scores (p = 0.058, p = 0.093), suggesting grip strength alone poorly predicts fall risk. This study confirms grip strength as a reliable muscle function measure but not a strong fall risk predictor. Age plays a dominant role, necessitating fall prevention strategies integrating balance, mobility, cognition, and environment. Renal function did not directly influence fall risk but may contribute indirectly through frailty, warranting further investigation.
Peran Apolipoprotein B, Apolipoprotein A, dan Rasio ApoA/ApoB sebagai Prediktor Terjadinya Demensia pada Kelompok Lanjut Usia Sim, Alfred Sutrisno; Santoso, Alexander Halim; Gunaidi, Farell Christian; Alifia, Khalisya; Aditya, Vincent; Destra, Edwin
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i1.4891

Abstract

Neurocognitive disorders, particularly dementia, affect various cognitive functions such as memory, attention, language, learning, and problem-solving, with the elderly population being the most impacted. The prevalence of dementia is projected to rise to 131 million cases by 2050, posing significant social and economic implications. This study employed a cross-sectional method to evaluate the role of Apolipoprotein A (APOA) and Apolipoprotein B (APOB) in the diagnosis and prevention of dementia in older adults. The results showed that Apolipoprotein A was not significantly correlated with MMSE scores, indicating no clear relationship between APOA and cognitive function. In contrast, Apolipoprotein B demonstrated a significant negative correlation with MMSE, suggesting that increased APOB levels are associated with cognitive decline. Elevated ApoB, linked to increased LDL and oxidative stress, correlated with reduced cognitive function, whereas ApoA, the main component of HDL, is associated with neuroprotective effects. These findings underscore the importance of monitoring lipid profiles, including ApoA and ApoB, in the prevention and management of dementia in the elderly.    
Co-Authors Aditya, Vincent Alifia, Khalisya AULIYA, LAHMY LAHMUL Aurellia, Aurellia Christian, Farell Destra, Edwin Febriastuti, Abebi Felicia, Ivana Goh, Daniel Gracieene Gracienne Gunaidi, Farell Christian Herlina Uinarni Kusuma, Kanaya Fide Pranata, Catherine Christiana Putra, Feri Yanto Putra, Muhammad Dzakwan Dwi Santoso, Alexander Halim Sitorus, Ribka Anggelline Hariesti Soeltanong, Dianova Teguh, Stanislas Kotska Marvel Mayello