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All Journal Jurnal Pelayanan dan Pengabdian Masyarakat (Pamas) Journal Pharmasci (Journal of Pharmacy and Science) Jurnal Pengabdian Kepada Masyarakat Itekes Bali Prosiding Seminar Nasional Biologi Jurnal Komunitas Farmasi Nasional Journal of Science and Social Development Jurnal Sains dan Kesehatan IJENSET
Galuh Gondo Kusumo
Akademi Farmasi Surabaya
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Identifikasi Senyawa Tanin Pada Daun Kemuning (Murraya panicullata L. Jack) Dengan Berbagai Jenis Pelarut Pengekstraksi Kusumo, Galuh Gondo; Ferry Fernanda, M.A. Hanny; Asroriyah, Heppy
Journal of Pharmacy and Science Vol. 2 No. 1 (2017): Journal of Pharmacy and Science
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v2i1.63

Abstract

ABSTRAKKemuning (Murraya paniculata L. Jack) adalah salah satu kekayaan alam yang memiliki banyak manfaat bagi kehidupan manusia. Tanin merupakan salah satu metabolit sekunder dari kemuning yang dapat digunakan sebagai anti diare dan pelangsing. Ekstrak kemuning didapatkan dari maserasi menggunakan tiga pelarut berbeda, yaitu metanol, etanol dan etil asetat. Tannin kemudian dipisahan dari ekstrak dengan menggunakan kromatografi lapis tipis (KLT) dengan berbagai jenis pelarut. Hasil nalisis menunjukkan bahwa pelarut terbaik untuk mengekstraksi tanin adalah metanol dengan perolehan 23,6989 g (31,59%). Skrining fitokimia yang dilakukan menggunakan dua reagen yang berbeda menunjukkan hasil yang positif mengandung tanin. Eluenterbaik untuk analisa tanin pada penelitian ini adalah dengan n-heksan-etil asetat (6 : 4) dengan nilai Rf sebesar 0,62.Kata Kunci : kemuning (Murraya paniculata L. Jack), tannin, kromatografi lapis tipis (KLT)ABSTRACTOrange Jessamine (Murraya paniculata L. Jack) is one of the natural treasures which has many benefits for human life. Tannin is one of secondary metabolite of orange jessamine that can be used as antidiarrhoeal and body slimming. It was obtained by maceration using 3 different solvents, such as : methanol, ethanol, and ethyl acetate. Tannins was separated from crude extract using thin layer chromatography (TLC) in different type of eluent. The analysis showed that the best solvent to extract tannin is methanol that produce of 23.6989 g (31.59%). The phytochemical screening test of the two reagents shows positif result contain tannin compound. The best eluent in this study aimed is n-hexane: ethyl acetate (6 : 4) with tannin Rf value of 0.62.Keywords: Orange jessamine (Murraya paniculata L. Jack), tannin, maceration, thin layer chromatography
Identification of Secondary Metabolites of Onion Peels Extract (Allium cepa L.) of Various Solvent: Identifikasi Senyawa metabolit Sekunder Ekstrak Kulit Bawang Merah (Allium cepa L.) dari Berbagai Macam Pelarut Mercyska Suryandari; Galuh Gondo Kusumo
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 7 No. 2 (2022): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v7i2.289

Abstract

Onion peels (Allium cepa L.) is often disposed of without being used and ends up as waste in markets that can pollute the environment. Onion peels can potentially be developed for treatment as an anti-cancer because of its phytochemical compounds. Previous studies have shown that secondary metabolites found in onion peels using different solvents produce different secondary metabolites. So the purpose of this study was to find out the secondary metabolite compounds from onion peels extract (Allium cepa L.) qualitatively when extracted using 5 different solvents. This research was conducted using a phytochemical screening method on the onion peels extract (Allium cepa L.). n-Hexane, Ethyl Acetate, Acetone, Ethanol 96%, and Chloroform were used in the maceration extraction method separately. The results showed that the yield value was 0.96%; 2.66%; 3.90%; 4.80%; 1.62%. The results showed that acetone, ethanol, and chloroform extracts of onion peels extract (Allium cepa L.) contained alkaloids, flavonoids, saponins, steroids, terpenoids, and tannins. Meanwhile, the ethyl acetate extract of onion peels contains alkaloids, flavonoids, steroids, terpenoids, and tannins. Lastly, the n-hexane extract of the onion peels only contains steroids and terpenoids. So it can be concluded that secondary metabolites in onion peels extract contain alkaloids, flavonoids, saponins, steroids, terpenoids, and tannins.
Antioxidan Activity from Methanol Extract of Kratom Leaves (Mitragyna speciosa) Maseration Result Using The DPPH Method: Aktivitas Antioksidan Ekstrak Metanol Daun Kratom (Mitragyna speciosa) Hasil Maserasi Menggunakan Metode DPPH Andhika Dwi Aristyawan; Anggi Ayu Windari; Mercyska Suryandari; Galuh Gondo Kusumo
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 8 No. 2 (2023): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v8i2.357

Abstract

Antioxidants are compounds that can prevent the formation of free radicals. Kratom is a typical plant from South Putussibau area, in West Kalimantan. The kratom plant contains alkaloids, triterpenoid-steroids, saponins, tannins and flavonoids. The main component of kratom leaves is an indole alkaloid that is efficacious as an antioxidant. The goal is to determine the antioxidant activity of kratom leaf extract (Mitragyna speciosa). The method used is the measurement of the reduced amount of DPPH from an antioxidant compound UV-Vis spectrophotometrically at a wavelength of 517nm using Vitamin C as a comparison. The extraction method used is maceration. The test was sampled 10 mg of kratom leaf extract (Mitragyna speciosa) with 10 ppm, 20 ppm, 30 ppm, 40 ppm, and 50ppm concentrations, then repeated 3 times. The results of the antioxidant activity of kratom leaves (Mitragyna speciosa) were expressed with IC50 values of 44,169 ± 0.5313 with an RSD value of 1.202%. Then it can be concluded that kratom leaf methanol extract (Mitragyna speciosa) has a very strong antioxidant activity with an IC50 value of 44,169 ± 0.5313 with an RSD value of 1.202%.
Identification of Secondary Metabolites of Garlic Peels Extract (Allium sativum) Mercyska Suryandari Mercyska; Galuh Gondo Kusumo; Ade Ferdinan
Jurnal Komunitas Farmasi Nasional Vol. 2 No. 2 (2022): Jurnal Komunitas Farmasi Nasional
Publisher : Akademi Farmasi Yarsi Pontianak

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Abstract

The use of garlic often only makes use of the root part, while the garlic skin is often thrown away without optimal utilization and ends up as waste. Garlic skin has the potential to be developed as a treatment, one of which is for cholesterol because it contains phytochemical compounds. Previous studies have shown that using different solvents during the extraction process will produce different secondary metabolites. So the purpose of this study was to find out the secondary metabolites of garlic skin extract (Allium sativum L.) qualitatively when extracted using 5 different solvents. In this research, the method used was phytochemical screening on garlic skin extract (Allium sativun L.). n-Hexane, Ethyl Acetate, Acetone, 96% Ethanol, and Chloroform using remaceration extraction method separately. The results showed that the yield value was 0.90%; 1.34%; 1.00%; 3.90%; 1.20%. The results showed that the n-Hexane extract of garlic (Allium sativum L.) peels contained steroids and terpenoids; ethyl acetate extract contains alkaloids, steroids and terpenoids; acetone extract contains saponins, steroids, terpenoids and tannins; 96% ethanol extract contains alkaloids, flavonoids, saponins, terpenoids, and tannins; and finally the chloroform extract of garlic skin contains alkaloids, steroids, terpenoids and tannins. So it can be concluded that the secondary metabolites in garlic peel extract contain alkaloids, flavonoids, saponins, steroids, terpenoids and tannins.the study, methods, results and conclusions, can describe qualitatiive and quantitative information.
PENINGKATAN PEMAHAMAN MASYARAKAT DESA DRENGES KABUPATEN BOJONEGORO TENTANG PENGGUNAAN OBAT MELALUI PENYULUHAN PENGUNAAN OBAT YANG BENAR Ilil Maidatuz Zulfa; Prasetyo Handrianto; Ratih Kusuma Wardani; Galuh Gondo Kusumo
Journal of Science and Social Development Vol. 1 No. 2 (2018): Journal of Science and Social Development
Publisher : Universitas Nahdlatul Ulama Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55732/jossd.v1i2.169

Abstract

Irrational drug use usually happens in self medication practise without any supervision from health care providers. Self medication practise usually does not consider the potential of allergic reaction, pregnancy, breast feeding, diet, and medication history.The promotion of rational drug use through communication, information, and education still need to be conducted to the community. This event is purposed to improve perception, knowledge, and attitude of Desa Drenges residents in the term of drug usage. A total 23 person of Desa Drengeswere enrolled in this eventfacilitated by village administrators.The perception, knowledge, and attitude of the residents recruited were evaluate through questionnaire filled before and after the event. The result showed the increase of perception, knowledge, and attitude of the residents up to 2,69%. From the result, The community service event can improve the quality of health of residents in Desa Drenges through the improvement of perception, knowledge, and attitude in the term of rational drug use.
UJI AKTIVITAS ANTIOKSIDAN TEH SEDUHAN DAUN ROSEMARY (Rosmarinus officinalis L.) DAN DAUN STEVIA (Stevia rebaudiana) DENGAN PERBANDINGAN (60:40) Mercyska, Mercyska Suryandari; Nur Indahwati, Sephia; Gondo Kusumo, , Galuh
Jurnal Komunitas Farmasi Nasional Vol. 3 No. 02 (2023): Jurnal Komunitas Farmasi Nasional
Publisher : Akademi Farmasi Yarsi Pontianak

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Abstract

Rosemary is an herbal plant whose content has compounds. Antioxidant that can prevent the occurrence of damage due to free addiction. This study wanted to find out the content of antioxidant that are obtained in steeping rosemary tea with using additional weetener stevia leaves. Antioxidant testing of leaf steeping tea. Rosemary and stevia leaves using the DPPH method observations were conducted at a wavelength of 522 nm, using a Vitamin C comparator. Replication was performed 3 times the treatment with a difference in brewing time of 5 minutes, 10 minutes and 15 minutes. From the results of the stury and observations obtained % Vitamin C concentration 1 ppm 15.45%, concentration 2 ppm 13.18%, concentration 3 ppm 26.52%, concentration 4 ppm 28.79%, concentration 5 ppm 38.33%. As for the result of % steeping rosemary leaf tea and stevia leaves on sample A brewed for 5 minutes on average % soaking 46.83%, sample B brewing for 10 minutes on average 32.01% dampening, and 15 minutes samle C brewing average % dampering 38.8%. The results of the antioxidant activity test of tea steeping rosemary leaves and stevia leaves in a ratio of (60:40) are that there is a strong antioxidant activity.
Formulasi dan Evaluasi Nano Partikel Ekstrak Etanol Daun Ubi Jalar Ungu (Ipomoea batatas L.) Varietas Antin-3: Formulation and Evaluation of Nano Particles Ethanol Extract of Purple Sweet Potato Leaves (Ipomoea batatas L.) Antin-3 Varieties Damaranie Dipahayu; Galuh Gondo Kusumo
Jurnal Sains dan Kesehatan Vol. 3 No. 6 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i6.818

Abstract

Ekstrak daun ubi jalar ungu (Ipomoea batatas Lamk) varietas Antin-3 (Ekstrak daun Antin-3) yang mengandung polifenol dan flavonoid yang memiliki kemampuan sebagai antioksidan. Polifenol dan Flavonoid memiliki bioavailabilitas yang rendah. Penelitian ini bertujuan untuk memperkecil ukuran partikel ekstrak menjadi nanopartikel sehingga penyerapan saluran cerna dapat meningkat serta evaluasi fisiknya untuk memastikan partikel nano seperti ukuran partikel (10-1.000 nm), indeks polidispersitas (PDI) ( < 0,5) dan nilai potensial zeta (±20mV sampai ±-30mV). Formulasi ekstrak nano dengan metode gelasi ionik menggunakan kitosan: NaTPP. Ada tiga Tiga sampel yang diteliti (F1:F2:F3) yaitu dengan perbandingan ekstrak daun Antin-3:kitosan:NaTPP (1:1:1 ); (1:5:1); (1:10:1). Evaluasi dilakukan dengan menggunakan PSA (Particle Size Analyzer). Hasil evaluasi sampel (F1:F2:F3) menggunakan PSA (Particle Size Analyzer) untuk ukuran partikel berturut-turut (1.482 nm; 564,38 nm; 734,36 nm); untuk PdI berturut-turut (0,3482; 0,4272; 0,381) dan untuk nilai potensial zeta masing-masing (5,19mV; 21,57mV; 33,4mV). F3 merupakan sampel yang memenuhi kriteria ukuran partikel, PdI dengan nilai zeta potensial
UU Edukasi Herbal 3S (Salam, Seledri, Dan Sirsak) Sebagai Terapi Antihiperkolesterolemia Di Smk Farmasi Surabaya Umar, Umarudin; Suryadari, Mercyska; ., Surahmaida; Kusumo, Galuh Gondo; Ulfa, Ninik Mas; Aristyawan, Andhika Dwi; ., Syukrianto
Jurnal Abdimas ITEKES Vol 4 No 1 (2024)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat Institute Teknologi dan Kesehatan (ITEKES) Bali

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37294/jai.v4i1.568

Abstract

Dampak buruk dari hiperkolesterolemia tidak hanya pada orang tua namun karena life style banyak anak-anak mengalami hiperkolestrolemia. Upaya yang dilakukan berdsarkan hasil wawancara dengan mengkonsumsi obat sintesis namun memiliki efek samping dan perlu upaya alternatif dengan memanfaatkan potensi herbal yang ada disekitar lingkungan yaitu 3S (Salam, Seledri dan Sirsak). Banyak penelitian yang menunjukkan bahwa daun salam dapat menurunkan kadar kolesterol baik berupa ekstrak maupun berupa minuman yaitu air rebusan dan jus daun salam.  Seledri dapat menurunkan kadar kolesterol atau sebagai terapi alternatif untuk antihipekolesterolemia. Sirsak sudh banyak diterapkan sebagai penurun kolesterol dengan cara direbus. Tujuan kegiatan ini adalah memberikan edukasi potensi 3S (Salam, Seledri dan Sirsak) sebagai terapi antihiperkolesterolemia, dimana nantinya dapat bermanfaat untuk masyarakat khususnya para remaja yang rentan terhadap penyakit degenerative. Metode pendekatan dengan penyuluhan dan edukasi. Kegiatan pengmas di hadiri oleh 30 siswa SMK Farmasi Surabaya dilakukan bulan 30 Januari 2024. Kegiatan pengmas ini dengan media edukasi powerpoint tentang pengetahuan antihiperkolestrolemia, terapi secara non farmakalogi 3S dengan potensi kandungan senyawa kimia  seperti flavonoid, tanin, dan minyak atsiri. Kandungan tersebut berpotensi untuk menurunkan antihiperkolestrolemia. Tingkat pengetahuan hasil pre test sebesar  57% dan post test menunjukan peningkatan tingkat pengetahuan siswa terhadap 3S sebagai terapi non farmaklogis antihiperkolestrolemia sebesar 97%. Kata kunci : antihiperkolestrolemia, 3S (Salam, seledri, dan sirsak), Non farmakalogi
ED IDENTIFIKASI METABOLIT SEKUNDER EKO ENZIM LIMBAH BUAH DAN SAYUR : IDENTIFIKASI METABOLIT SEKUNDER EKO ENZIM LIMBAH BUAH DAN SAYUR Bawanda, Edward Melfin; Umarudin Umarudin; Syukrianto; Galuh Gondo Kusumo; Ramadhan Renaisansa; Widya Dara Anindya; Silvi Ayu Wulansari; Vika Ayu Devianti
Jurnal Komunitas Farmasi Nasional Vol. 5 No. 01 (2025): Jurnal Komunitas Farmasi Nasional
Publisher : Akademi Farmasi Yarsi Pontianak

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Abstract

Organic waste, in the form of fruit and vegetable peels from Ketintang, Surabaya City, East Java, can be processed into an eco enzyme through fermentation using a mixture of sugar and water over a period of 30 days. During this process, glucose is broken down into pyruvic acid, which, under anaerobic conditions, undergoes decarboxylation to form ethanol and carbon dioxide. This study aims to identify the secondary metabolites present in eco enzymes derived from fruit and vegetable waste. This research employed an accurate experimental method, observing colour changes in the tests for flavonoids and tannins, the presence of froth in the saponin test, the formation of rings in the steroid and terpenoid tests, and the appearance of precipitate in the alkaloid test. The analysis results indicated that the eco-enzyme from fruit and vegetable waste tested positive for flavonoids, tannins, and saponins, while alkaloids, terpenoids, and steroids were not detected (negative).
EDUKASI TENTANG TANAMAN OBAT ASLI INDONESIA YANG BERPOTENSI SEBAGAI AFRODISIAK BAGI PRIA DI SMK FARMASI Umarudin, Umarudin; Ulfa, Ninik Mas; Kusumo, Galuh Gondo; Syukrianto, Syukrianto
Prosiding Seminar Nasional Biologi Vol. 13 (2025)
Publisher : Prosiding Seminar Nasional Biologi

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Abstract

Tujuan dari kegiatan ini adalah memberikan edukasi kepada siswa SMK Farmasi tentang tanaman obat asli Indonesia yang berpotensi sebagai afrodisiak. Metode pelaksanaannya meliputi sesi edukasi, sesi tanya jawab, dan diskusi. Media yang digunakan berupa slide PowerPoint, foto tanaman, dan simplisia (bahan tanaman kering) dari tanaman obat asli Indonesia yang dikenal memiliki sifat afrodisiak. Sebelum penyampaian materi, dilakukan pre-test dan dilanjutkan dengan post-test di akhir kegiatan. Hasil kedua tes dianalisis menggunakan tabulasi grafik. Hasil pre-test menunjukkan skor rata-rata 40 dari 100, yang mencerminkan pemahaman awal siswa tentang tanaman asli Indonesia yang berpotensi afrodisiak. Selanjutnya, diberikan edukasi tentang tiga tanaman herbal yang diperkenalkan kepada siswa SMK Farmasi: lada Jawa (Piper retrofractum) yang berasal dari Madura dan Jember; purwaceng (Pimpinella alpina atau Pimpinella pruatjan) yang bersumber dari Dataran Tinggi Dieng, Jawa Tengah; Gunung Semeru dan Pegunungan Tengger, Jawa Timur; Gunung Pangrango, Jawa Barat; serta Gunung Lawu dan Gunung Galunggung; dan pasak bumi (Eurycoma longifolia) yang ditemukan di Sumatra dan Kalimantan. Edukasi awal ini bertujuan mengurangi ketergantungan pada obat sintetis yang sering menimbulkan efek samping. Hasil post-test menunjukkan peningkatan dengan skor rata-rata 98. Kegiatan ini memberi kontribusi positif dengan memperluas pengetahuan siswa tentang morfologi tanaman, habitus, dan efek farmakologis sebagai afrodisiak pada pria, yang didukung oleh studi ilmiah. Selain memberi manfaat bagi siswa, inisiatif ini juga memberikan wawasan berharga bagi masyarakat luas sebagai langkah penting untuk meningkatkan kesehatan reproduksi secara menyeluruh melalui pendekatan alami dan berbasis pengetahuan.
Co-Authors ., Syukrianto Ade Ferdinan Anggi Ayu Windari Anindya, Widya Dara Aristyawan, Andhika Dwi Asroriyah, Heppy Bawanda, Edward Melfin Damaranie Dipahayu Devianti, Vika Ayu Fernanda, MA Hanny Ferry M.A. Hanny Ferry Fernanda Mercyska Suryandari Nia Dwi Wahyuning Arum Nur Indahwati, Sephia Octifany, Salsabila Pertiwi, Husadhani Dwi Prasetyo Handrianto Ramadhan Renaisansa Ratih Kusuma Wardani Renaisansa, Ramadhan Siti Annurijati Hatidja Sri Safitri Surahmaida, Surahmaida Suryadari, Mercyska Syukrianto Syukrianto, Syukrianto Ulfa, Ninik Mas Umar, Umarudin Umarudin Umarudin, Umarudin Wulansari, Silvi ayu Yuliarni, Floreta Fiska Zulfa, Ilil Maidatuz