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All Journal Jurnal Review Pendidikan dan Pengajaran (JRPP) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Jurnal Pembelajaran dan Biologi Nukleus Indonesian Journal of Pharmaceutical and Clinical Research Science Midwifery Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Farmanesia FARMASAINKES Nusantara Scientific Medical Research Journal Jurnal ABDIMAS MUTIARA
Yosy Cinthya Eriwaty Silalahi
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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FORMULASI NANOPARTIKEL DARI LIMBAH EKSTRAK KULIT NANAS (Ananas comosus L.) DALAM BENTUK TEH SEDUHAN Rahmi, Sofia; Sari, Rika Puspita; Harahap, Nurul Dahlia; Siahaan, Jekson Martiar; Mega, Juli Yosa; Silalahi, Yosy Cinthya Eriwaty
JURNAL FARMASI, SAINS, dan KESEHATAN Vol. 5 No. 2 (2026): FARMASAINKES: JURNAL FARMASI, SAINS dan KESEHATAN
Publisher : Fakultas Farmasi Universitas Muslim Nusantara Al Washliyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/farmasainkes.v5i2.6263

Abstract

Limbah kulit nenas memiliki kandungan gizi karbohidrat, protein, gula reduksi, serat kasar dan air. Kulit nenas juga memiliki metabolit sekunder alkaloid, flavonoid, saponin dan tanin. Spesifikasi dari senyawa flavonoid ekstrak kulit nenas yaitu senyawa kuersetin. Limbah kulit nenas jika dikonsumsi dalam bentuk rebusan kurang diminati karena berbau langu atau jamu. Penelitian ini dilakukan untuk memanfaatkan limbah kulit nanas menjadi sediaan nanopartikel dalam bentuk teh seduhan. Pembuatan nanopartikel ekstrak diawali dari pembuatan ekstrak dan kemudian dilakukan pencampuran dengan bahan kitosan serta NaTPP dengan perbandingan (1:1:1; 1:5:1 dan 1:10:1), kemudian dihomogenizer dengan kecepatan 4000 rpm selama 90 menit dan freeze drying selama 1x24 jam untuk mendapatkan nanopartikel kering. Dilakukan evaluasi sediaan seperti organoleptis, ukuran partikel, dan zeta potensial. Hasil yang pada organoleptis yaitu berwarna coklat, berbau khas dan berbentuk bubuk. Hasil ukuran partikel diperoleh F3 memiliki ukuran partikel terkecil (145,267±0.06) nm dan zeta potensial (30.27±0.12) mV. Kesimpulan dari penelitian ini yaitu F3 (ekstrak:kitosan:NaTPP dengan perbandingan 1:10:1) memiliki hasil terbaik dibandingkan formula lainnya.
Standardization of Rhizome Simplicia from the Zingiberaceae Family in Terms of Methods and Quality: A Review Silalahi, Yosy Cinthya Eriwaty; Surbakti, Christica Ilsana; Suharyanisa, Suharyanisa; Suryani, Monica; Ulfata, Zikri; Panjaitan, Grace Emmas Sondang; Marbun, Eva Diansari
NSMRJ: Nusantara Scientific Medical Research Journal Vol. 3 No. 02 (2025): NSMRJ: Nusantara Scientific Medical Research Journal
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/nsmrj.v3i02.128

Abstract

Simplicia rhizomes from the Zingiberaceae family are important raw materials in the traditional medicine industry, as they contain bioactive compounds such as flavonoids, alkaloids, and tannins. The quality of simplicia is strongly influenced by post-harvest processing methods, particularly drying. This study aims to systematically review the quality of Zingiberaceae rhizome simplicia based on ten national scientific journals published between 2015 and 2024. The method employed was a literature study using a qualitative descriptive approach, evaluating specific quality parameters (organoleptic characteristics, solubility, and phytochemical tests) and non-specific parameters (moisture content, ash content, and microbial contamination) according to the Indonesian Herbal Pharmacopoeia. The results indicate that oven drying at 50–60 °C for 24–48 hours produces the best-quality simplicia, characterized by moisture content below 10%, ash content within acceptable limits, and high flavonoid levels. Other drying methods, such as sun drying and natural air drying, showed more variable outcomes and in some cases exceeded standard limits, particularly in acid-insoluble ash levels and microbial contamination. Several simplicia samples obtained from traditional markets did not meet quality standards due to suboptimal washing and storage processes. This study concludes that simplicia quality standardization must comprehensively address technical stages from washing to drying. The use of extracts is more strongly recommended than raw simplicia to ensure consistency, stability, and safety of herbal products. Strict quality standards are essential to support the effectiveness of traditional medicines derived from Zingiberaceae.
Co-Authors Adiansyah Adiansyah, Adiansyah Ahmad Hafizullah Ritonga Asmaradhani, Dian Dalimunthe, Agusmal Dicky Yuswardi Wiratma Eka Margareta Sinaga Ginting, Nahitma Harahap, Nurul Dahlia Harefa, Karnerius Hayati, Sry Hutabarat, Vitrilina Jansen Silalahi Khairunnisa Khairunnisa Lida Karo Karo Manurung, Kesaktian Marbun, Eva Diansari Marpaung, Jon Kenedy Mega, Juli Yosa Monica Suryani Nasution, Dinda Juita Nasution, Khairina Nurussakinah, Nurussakinah Panjaitan, Grace Emmas Sondang PUJI LESTARI Purba, Trionaldo Purwandari, Vivi Rahmi, Sofia Rayhana, Rayhana Rika Puspita Sari Siahaan, Jekson Martiar Sianipar, Artha Yuliana Sinaga, Lia Rosa Veronika Siti Maimunah Siti Morin Sinaga Siti Nurbaya Sitompul, Erly Sitorus, Elly Sitorus, Elly Nurita Suharyanisa Supartiningsih - - Surbakti, Christica Ilsana Tambunan, Rika Puspita Tarigan, Malemta Tarigan, Mira Eka Diana Br Telaumbanua, Realisni Thaib, Cut Masyithah Turnip, Icha Wahyuni Ulfata, Zikri Yusuf, Faisal Zuhairiah Nasution, Zuhairiah