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Effect of Purple Leaf (Graptophyllum pictum (L.) Griff) Emulsion on the Histological Parameters of Streptozotocin-Induced Diabetic Rats Dewi, Niluh Puspita; Dewik, Komang; Alaydrus, Syafika; Kasim, Athia Kurnia; Polontalo, Nani Astria; Wirawan, Wayan; Andini, Dian; Irma, Irma; Fatu, Imelda Synthia
Jurnal Penelitian Pendidikan IPA Vol 12 No 1 (2026)
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v12i1.14172

Abstract

Damage to vital organs such as the liver, kidneys, and pancreas is a common complication of diabetes mellitus, characterized by chronic hyperglycemia due to pancreatic cell dysfunction. Graptophyllum pictum (purple leaf) is a potential herbal therapy containing bioactive compounds with antioxidant and organ-protective effects. This study aimed to evaluate the effect of purple leaf emulsion on blood glucose levels and the histopathological features of diabetic rats induced by streptozotocin. Rats were divided into six groups: normal control, negative control, positive control (glibenclamide), and three doses of purple leaf emulsion (100, 200, and 300 mg/kg BW). After 28 days of treatment, the emulsion significantly reduced blood glucose levels and improved the histological structures of the liver, kidneys, and pancreas. The 200 mg/kg BW dose was most effective for pancreatic protection, while 300 mg/kg BW provided optimal hepatoprotective and renoprotective effects. These findings highlight the potential of purple leaf as a natural antidiabetic and organ-protective agent.
EDUKASI PEMANFAATAN SEDUHAN DAUN TEH HIJAU SEBAGAI ANTIKARIES DI DESA BOSA KEC. TAWAELI, SULAWESI TENGAH R, Sririzqi Muthmainnah A.; Alaydrus, Syafika; Mariyani, Mariyani; Utami, Faikah Dyah; Djumiran, Sandra Sri Dewi; Tamuntuan, Annisa Fitria
Jurnal Abdi Insani Vol 13 No 1 (2026): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v13i1.2775

Abstract

Bosa Village is categorized as a 3T priority area (Frontier, Outermost, and Disadvantaged), resulting in a lack of dental health facilities and limited public knowledge regarding the dangers of dental caries, as well as a lack of understanding of utilizing plants for disease prevention. Shredded green tea leaves (Camellia sinensis) are a widely available commercial product that can be utilized for dental caries prevention due to their antibacterial properties. Therefore, the objective of this community service is to educate the public on dental caries prevention, specifically through the formulation of mouthwash from steeped green tea leaves to enhance knowledge of dental health maintenance using accessible products. The method employed was the lecture method, complemented by the distribution of brochures. This was followed by a recall of the material through a Q&A session. The results showed a significant improvement in the participants' competence between the pre-test and post-test. Although participants initially lacked understanding in several aspects, there was a substantial increase in comprehension following the post-test. This improvement was evident after the community of Bosa, Hamlet II, received education on utilizing green tea leaves as a mouthwash for dental caries prevention. Consequently, the community has begun to understand the prevention and maintenance of oral health, including the use of shredded green tea leaves as an anti-caries mouthwash.