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All Journal JURNAL PROMOSI KESEHATAN INDONESIA Berkala Ilmu Kesehatan Kulit dan Kelamin MNJ (Malang Neurology Journal) AKSIOLOGIYA : Jurnal Pengabdian Kepada Masyarakat Empowerment : Jurnal Pengabdian Masyarakat Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Jurnal Kesehatan Molucca Medica Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) JHeS (Journal of Health Studies) Poltekita: Jurnal Pengabdian Masyarakat Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Titaley, Christiana Rialine
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Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Edukasi Interaktif Pencegahan Stunting untuk Ibu Hamil di Puskesmas Poka–Rumah Tiga Ambon: Interactive Education on Stunting Prevention for Pregnant Women at Poka–Rumah Tiga Health Center, Ambon Tando, Yudhie Djuhastidar; Titaley, Christiana Rialine; Que, Bertha Jean; Taihuttu, Yuniasih Mulyani Jubeline; Angkejaya, Ony Wibriyono; Oetama, Evan Christian; Liyani Sartika Sara; Siwtiory, Ezra Puthrien A.
Poltekita: Jurnal Pengabdian Masyarakat Vol. 5 No. 2 (2024)
Publisher : Pusat Penelitian & Pengabdian Masyarakat Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/pjpm.v5i2.2308

Abstract

Stunting, a form of growth and development impairment due to chronic undernutrition, is a major threat to the quality of human resources. Faculty of Medicine, Pattimura Unversity Ambon, conducted a health education activity aimed at increasing the knowledge of pregnant women and their husbands regarding the importance of efforts to prevent stunting since the pregnancy period. This activity was carried out on 21 December 2021 involving 55 participants consisting of pregnant women and their husbands living in the catchment area of ​​the Poka-Rumah Tiga Health Center, Ambon City. The activity included: 1) Provision of educational materials from resource persons 2) Evaluation of participant knowledge (pre and post-test), and 3) Distribution of promotional media (leaflets) to participants. This activity received positive responses from the Ambon City Health Office, Poka-Rumah Tiga Health Center, and all participants who attended the training. The pre-test assessment before the education sessions showed that 2% of participants had a 'low' level, 45% had a 'moderate' level and 53% had a 'high' level of knowledge about stunting and its prevention. However, in the post-test assessment after the end of the education session, none had a 'low' level of knowledge, only 25% had a ’moderate’ level and 75% of participants had a 'high' level of knowledge. The results indicated an increased level of knowledge in pregnant women and their husbands about the importance of stunting prevention since pregnancy after the training. This educational activity could be carried in the future by involving pregnant women in other areas in Ambon City.
Kepatuhan Minum Obat Pencegahan Filariasis di Wilayah Kerja Puskesmas Waihaong dan Air Salobar Kota Ambon Iwan, Ressita Fannia; Titaley, Christiana Rialine; Taihuttu, Yuniasih; Krentel, Alison
Jurnal Promosi Kesehatan Indonesia Volume 16 No.2 Agustus 2021
Publisher : Master Program of Health Promotion Faculty of Public Health Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jpki.16.2.44-55

Abstract

Background: Lymphatic Filariasis (LF) is an infectious disease caused by filarial worms and transmitted by mosquitoes. Mass drug administration (MDA) for LF is used in endemic areas to stop transmission and prevent disability due to LF. This study aims to identify factors associated with overall compliance with the MDA in 2018 in the catchment areas of Waihaong and Air Salobar Health Centers, Ambon. Method: This analysis used data derived from a survey conducted by the Faculty of Medicine Pattimura University, Ambon, in January 2019. We used information from 745 subjects who received LF drugs in both study areas. Logistic regression analysis was employed to determine factors associated with community compliance with taking filariasis drugs. Results: Our study found that only 67% of the community swallowed LF drugs (60,3% in Waihaong and 72,6% in Air Salobar). Higher compliance with swallowing the LF drugs was found in respondents living in the catchment area of Air Salobar Health Center (OR=2,01, 95%CI:1,42-2,86, P-value<0,001);with a high level of knowledge (OR=1,91, 95%CI:1,34-2,74, P-value<0,001 and with a high sense of trust towards the drugs deliverers (OR=4,93, 95%CI:2,17-11,22, Pvalue<0,001). Furthermore, respondents who felt a high moral obligation to take the drugs (OR=2,39, 95%CI:1,15-4,94, P-value=0,019); and received social support to take the drugs (OR=5,12, 95%CI:3,18-8,23, P-value<0,001) were also more likely to comply with treatment. This study shows that health promotion interventions to increase community awareness and knowledge are still required in Ambon City despite many rounds of mass drug administration. Various educational media and efforts to increase knowledge and capabilities of the drug deliverers are essential to improve community compliance with taking LF drugs.
Utilization of Family Planning Contraceptives among Women inthe Coastal Area of South Buru District, Maluku, 2017 Titaley, Christiana Rialine; Sallatalohy, Ninik
Kesmas Vol. 15, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Maluku Province is one among provinces in Indonesia with a contraceptive prevalence rate (CPR) lower than the national average. This study aimed toexamine factors associated with the utilization of family planning contraceptives among women of reproductive age living in the coastal area of South BuruDistrict, Maluku, Indonesia. Data were derived from a household health survey conducted in five subdistricts in South Buru, e.g., Namrole, Leksula, Waesama,Kapala Madan and Ambalau Subdistricts on November 2017 by the Faculty of Medicine, Pattimura University in Ambon. Information on contraceptive usewere collected from 390 married women aged 20 - 49 years. Bivariate and multivariate logistic regression analysis were employed to examine the factorsassociated with utilization of family planning contraceptives. This study found a low rate of utilization of family planning contraceptives (38.5%). The odds ofutilization modern contraceptive significantly reduced among women living in Ambalau and Leksula Subdistricts, aged 41 - 49 years, those who intend to havemore number of children, and with a low level of knowledge about family planning contraceptive methods.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN ANEMIA IBU BALITA DI WILAYAH KERJA PUSKESMAS TULEHU KABUPATEN MALUKU TENGAH TAHUN 2025 Zain, Marwah Mahrusah; Latuconsina, Vina Zakiah; Mainase, Josepina; Pattiasina, Firensca; Titaley, Christiana Rialine; Soumena, Rif’ah Zafarani; Hataul, Is Asmaul Haq
Molucca Medica Vol 18 No 2 (2025): VOLUME 18, NOMOR 2, OKTOBER 2025
Publisher : Pattimura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/molmed.2025.v18.i2.108

Abstract

Latar Belakang: Anemia merupakan kondisi ketika kadar hemoglobin dalam darah menurun, sehingga kemampuan darah untuk mengangkut oksigen berkurang. Ibu balita termasuk dalam kelompok yang rentan anemia. Kesehatan ibu balita sangat penting untuk diperhatikan, karena kondisi kesehatan ibu memiliki keterkaitan dengan kesehatan balita. Tujuan: Penelitian ini dilakukan dengan tujuan untuk mengetahui faktor-faktor yang berhubungan dengan kejadian anemia ibu balita di wilayah kerja Puskesmas Tulehu Kabupaten Maluku Tengah tahun 2025. Metode: Desain penelitian yang digunakan, yaitu analitik kuantitatif dengan pendekatan cross sectional. Data yang digunakan merupakan data primer yang dikumpulkan dengan teknik proportional stratified sampling dan purposive sampling. Jumlah sampel yaitu 91 sampel yang diambil pada 15 dusun di wilayah kerja Puskesmas Tulehu. Data yang dikumpulkan dianalisis secara bivariat dengan uji chi square dan Fisher exact. Hasil penelitian ini memperlihatkan bahwa proporsi anemia ibu balita yaitu 16,5%. Hasil: Hasil analisis bivariat menunjukkan bahwa tidak terdapat hubungan antara usia (p=0,371), pendidikan (p=0,122), pekerjaan (p=0,200), kondisi ekonomi (p=0,729), dan paritas (p=0,106) dengan kejadian anemia, sedangkan ditemukan terdapat hubungan antara IMT (p=0,002), LILA (p=0,006), pola makan (p=0,016), dan tingkat pengetahuan (p=0,025) dengan kejadian anemia. Ibu balita dengan status gizi kurang, pola makan buruk, dan pengetahuan rendah lebih berisiko mengalami anemia. Kesimpulan: Kesimpulannya, status gizi, pola makan, dan tingkat pengetahuan berhubungan dengan anemia ibu balita. Peningkatan pengetahuan anemia dan perilaku gizi melalui program edukasi kesehatan yang berkesinambungan serta pemantauan status gizi ibu balita merupakan upaya yang perlu dilakukan guna mengurangi angka kejadian anemia pada ibu balita
DIAGNOSTIC AND PROGNOSTIC VALUE OF CIRCULATING miRNAs AS NON-INVASIVE BIOMARKERS IN GLIOBLASTOMA MULTIFORME: A SYSTEMATIC REVIEW AND META-ANALYSIS Akas, Ignasius Dede Setyo; Seleky, Cherlyn; Febriani, Reka; Titaley, Christiana Rialine; Huwae, Laura Bianca Sylvia
MNJ (Malang Neurology Journal) Vol. 12 No. 2 (2026): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2026.012.02.14

Abstract

Background: Glioblastoma multiforme (GBM) is most prevalent and aggressive form of glioma, characterized by a high mortality rate and significant effect on patient's quality of life. The challenges in diagnosing, treating, and predicting prognosis of GBM highlight the need for more reliable biomarkers.  Promising characteristics as noninvasive biomarkers have been identified in microRNA (miRNAs) to their critical role in glioblastoma pathogenesis. Objective: Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 standards guided implementation of this systematic review and meta-analysis examining diagnostic and prognostic relevance of microRNAs in GBM as non-invasive biomarkers. A total of 9 studies on diagnostic accuracy and 6 studies on prognostic analysis were included. Articles were identified through comprehensive searches in PubMed, EBSCO, and Wiley databases. Availability of diagnostic indicators such as area under curve (AUC), sensitivity, and specificity for miRNA-based diagnosis, along with survival measurements reported as hazard ratios (HRs) or mean survival outcomes, constituted main inclusion requirements for original studies. Results: In meta-analysis, circulating miRNAs achieved notable diagnostic performance, supported by sensitivity and specificity values of 0.86 and 0.92, respectively, along with AUC of 0.93. Subgroup analysis was then performed to assess consistency of accuracy based on ethnicity, sample source, dysregulation category, and miRNA profile mapping. Certain miRNAs also showed promise as prognosis markers as they are involved in glioblastoma progressivity. Conclusion: Circulating miRNAs demonstrate high accuracy as non-invasive biomarkers for GBM diagnosis and prognosis. Their role in glioblastoma progression suggests potential applications in more precise therapeutic approaches.
Co-Authors Abbas, Mutmainnah Aini, Tarisha Noer Akas, Ignasius Dede Setyo Amanda Gracia Manuputty Angkejaya, Ony Wibriyono Bandjar, Fitri Kadarsih Bension, Johan Bruiyf Christian Oetama, Evan Djoko, Sri Wahyuni Elpira Asmin Febriani, Reka Harahap, Iqbal Alaudilah Hataul, Is Asmaul Haq Huwae, Laura Bianca Slyvia Huwae, Laura Bianca Sylvia Iwan, Ressita Fannia Jean Que, Bertha Kailola, Nathalie Elischeva Krentel, Alison Latuconsina, Vina Zakiah Laura Bianca Sylvia Huwae Liyani Sartika Sara Maelissa, Merlin Margareth Maelissa, Merlin Margreth Mailera, Damara Herlis Mainase, Josephina Mainase, Josepina Malakauseya, Maxwell Landri Vers Mulyani Jubeline Taihuttu, Yuniasih Nari, Janti Pare Oetama, Evan Christian Pangestu, Juan Felix Pattiasina, Firensca Pattipeilohy, Claudia Igreya Pentury, Rosano Carolina Prasetijo, Muhammad Raditya Que, Bertha Jean Saija, Alessandra Sallatalohy, Ninik Sara, Liyani Sartika Seimahuira, Theresia Seleky, Cherlyn SILALAHI, PARNINGOTAN YOSI Siwtiory, Ezra Puthrien A. Soumena, Rif’ah Zafarani Tahitu, Ritha Taihuttu, Yuniasih MJ Taihuttu, Yuniasih Mulyani Jubeline Tanamal, Rita Tando, Yudhie Djuhastidar Tauran, Yaustien Shenny Tuahatu, Ivana Uniplaita, Agatha Gavia Zain, Marwah Mahrusah