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All Journal Farmaka International Journal of Integrated Health Sciences Jurnal Farmasi Klinik Indonesia Global Medical and Health Communication JURNAL PENDIDIKAN KEPERAWATAN INDONESIA Jurnal Kebidanan Jurnal Kesehatan Bakti Tunas Husada JURNAL PENDIDIKAN JASMANI DAN OLAHRAGA NurseLine Journal Jurnal Keperawatan Padjadjaran Jurnal Kesehatan Manarang Majalah Kedokteran Andalas Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Journal of Applied Nursing and Health JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Jurnal Kesehatan Bakti Tunas Husada Media Penelitian dan Pengembangan Kesehatan Indonesian Journal of Electronics, Electromedical Engineering, and Medical Informatics
Shelly Iskandar
Departemen Ilmu Kedokteran Jiwa, Fakultas Kedokteran, Universitas Padjadjaran/ RSUP Dr. Hasan Sadikin Bandung
Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Education Electrical & Electronics Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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CATECHOL-O-METHYLTRANSFERASE VAL158MET GENE POLYMORPHISM IN SCHIZOPHRENIA RISPERIDONE-TREATED PATIENTS Fitri N. Ramadhani; Ajeng Diantini; Shelly Iskandar; Melisa I. Barliana
Farmaka Vol 18, No 4 (2020): Farmaka (Suplemen)
Publisher : Fakultas Farmasi, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/farmaka.v18i4.42482

Abstract

Catechol-O-Methyltransferase (COMT) gene is located at chromosome 22q11 on a location with a high risk of the occurrence of schizophrenia that has a role in the degradation and inactivation of dopamine neurotransmitters. The COMT Val158Met gene polymorphism has enzymatic activity variation that can affect the availability of COMT enzyme, balance of dopamine level, and availability of dopamine receptors so it can influence the effectiveness of risperidone therapy that varies. The aim of this study was to observe the genetic profile of COMT Val158Met gene polymorphism and its correlation with effectiveness of risperidone therapy either single or combination in schizophrenia patients at Mental Hospital of Prof. Dr. Soerojo Magelang. This study was an observational descriptive study with a cross-sectional plan. Data collection was carried out prospectively through assessment of risperidone therapy effectiveness based on PANSS-EC scores in medical record, whole blood sampling, and identification of COMT Val158Met gene polymorphism using Polymerase Chain Reaction-Amplification Refractory Mutation System (PCR-ARMS) method. The result of study showed that all schizophrenia patients at Mental Hospital of Prof. Dr. Soerojo Magelang had heterozygote Val/Met (GA) genotype. Combination risperidone therapy was the most widely used (90.79%) rather than single with the result that 44 patients of 69 patients (63.77%) responded to the combination risperidone. Combined risperidone clozapine therapy was the most widely used (57.97%) with the result that 23 patients out of 40 (57.50%) responded to the combination therapy.
The life experiences of adolescent female students who use social media Khairiyatul Munawwarah; Shelly Iskandar; Imas Rafiyah
Jurnal Keperawatan Padjadjaran Vol. 10 No. 3 (2022): Jurnal Keperawatan Padjadjaran
Publisher : Faculty of Nursing Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkp.v10i3.2097

Abstract

Background: Social media is a place for students to follow trends. However, Islamic boarding schools limit students by prohibiting them from bringing cell phones; therefore, they are not influenced by the outside world, even online.Purpose: The purpose of this study is to explore the experiences of female students as users of social media related to dormitory rules.Methods: Using a qualitative research design with a phenomenological approach. The research was conducted by in-depth interviews with 8 female students at Madrasah Ulumul Qur'an Langsa aged 15-18 years. Interview transcripts were analyzed using the Colaizzi method.Results: Six themes emerged from this study including: students bring cell phones to boarding schools because of the influence of friends and want to see updates, the use of social media as entertainment in their spare time, social media affects the way students follow fashion, the influence of the outside environment is more dominant on the behavior of students than the media in social media. The values instilled in the pesantren become a bulwark in the face of the outside world, and students want to make the best use of social media.Conclusions: Female students want to make the best use of social media to atone for the violations committed. They also agree that the prohibition of bringing cell phones and access to social media in Islamic boarding schools is the right thing because it can cause negligence and jealousy in friends who do not carry cell phones.
Studi Literatur: Predisposing, Enabling, dan Reinforcing Factors Terjadinya Perilaku Seksual Pranikah pada Remaja Hardiyati Hardiyati; Shelly Iskandar; Taty Hernawaty
Jurnal Kesehatan Manarang Vol 5 No 2 (2019): Desember 2019
Publisher : Politeknik Kesehatan Kemenkes Mamuju

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33490/jkm.v5i2.106

Abstract

Adolescent behaviors that have the potential to cause problems that often occur and are most prominent among adolescents are some high-risk behaviors including experiences of sexual violence and premarital sexual behavior. Changes that occur in adolescents ranging from physical, psychological, and social changes that risk causing problems because they are hanging out with peers and feel attracted to the opposite sex. The impact of sexual behavior on adolescents results in abortion, unwanted pregnancy, death, increased incidence of HIV/AIDS as well as an increase in juvenile crime in adolescents. The purpose of this literature study is to identify early predisposing factors, enabling factors, and reinforcing factors that influence premarital sexual behavior. The method used in writing this literature study with internet searches from Proquest, CINAHL, EBSCOHost, Pubmed, Google Scholar and nursing books from 2000 – 2014 with the keywords Premarital sexual behavior. Predisposing factors include dating status, dating frequency, and knowledge. Enabling factors include the use of smartphones and reinforcing factors are religious norms and family norms. It can be concluded that several factors that influence the occurrence of premarital sexual behavior include dating status, frequency of dating, knowledge, smartphone usage, religious norms and family norms. The high influence of premarital sexual behavior shows that health promotion programs must be focused on increasing positive and supportive values, as well as the need for skills training so that adolescents can avoid premarital sexual behavior.
Perbandingan Skor Positive and Negative Syndrome Scale Antara Skizofrenia Awitan Remaja dan Awitan Dewasa Priskila Gracianita; Veranita Pandia; Shelly Iskandar; Mohammad Ghozali
Majalah Kedokteran Indonesia Vol 70 No 8 (2020): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.70.8-2020-273

Abstract

Introduction: Adolescent-onset schizophrenia patients cover a small fraction of schizophrenia population, with greater symptoms’ degree of severity, affecting patients’ quality of life. One of the instruments which measures schizophrenia symptom severity is Positive and Negative Syndrome Scale (PANSS). This study’s purpose is to know the demographic characteristic and compare the PANSS scores between adolescent-onset and adult-onset schizophrenia. Method: This study is a cross-sectional descriptive study done throughout November 2019–February 2020. This study uses secondarily-sourced data from the schizophrenia patients’ medical records admitted in Dr. Hasan Sadikin Central General Hospital’s in 2018, sampled through total sampling and calculated using Mann-Whitney U test. Result: Result of this study shows that most adolescent-onset schizophrenia patients are male, middle-level educated, unemployed, and unmarried. Statistically significant difference is not found in total score, positive scale, negative scale, and general psychopathology scale. It is also found that in general psychopathology scale, adolescent-onset patient scored higher than adult-onset patients on “unusual thought content” between the two onsets (p=0,01).Conclusion: Adolescent-onset in schizophrenia is not significantly different to adult-onset in PANSS score, though it is significant in unusual thought content in general psychopathology scale.
Effectiveness of Multimedia and Education using Lecturing Method on Role of Vitamin D for Health Cadres Sumartini Dewi; Adityana Sulistyo; Erwin Sumardi; Eka Puji Lestari; Kevin Sulay Wijaya; Paramitha Kusuma; Theresia Dewi; Agraini Agraini; Eldi Sauma; Winda Kurniati; Francisca Nungki Triandari; Shelly Iskandar; Tuti Kurnianingsih; Veranita Pandia
International Journal of Integrated Health Sciences Vol 9, No 2 (2021)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v9n2.2243

Abstract

Objective: To investigate the differences in the effectiveness of learning methods between multimedia and lecture methods on benefits of vitamin D for health from the perspective of health cadres' knowledge,. Methods: This study was an experimental study with a pre-and post-test design. The knowledge of health cadres was assessed using a questionnaire. The questionnaire was distributed before and after the health cadres received vitamin D education by two different methods. Data analysis was conducted using paired and independent t-test with a significance level of p <0.05. Results: A total of 59 health cadres participated in this study. Prior to education, the median test score for the multimedia group was 9.45, while the median test score for the lecture group was 82.70. After the education, the multimedia group and the lecture group got a median test score of 10.84. The multimedia method and lecture method significantly increased health cadres' knowledge with p-values of <0.02 and 0.003, respectively. There was no difference in the multimedia method's effectiveness compared to the lecture method in increasing the knowledge of health workers about vitamin D's role in health (p=0.62). Conclusion: The multimedia education method is as effective as the lecture method in increasing health cadres' knowledge about the role of vitamin D in health. 
EFEKTIVITAS INTERVENSI SELF-MANAGEMENT TERHADAP ADHERENCE TO RECOMMENDED REGIMEN PADA KLIEN SKIZOFRENIA DI WILAYAH PUSKESMAS PURWADADI KECAMATAN PURWADADI KABUPATEN CIAMIS Reni Hertini; Shelly Iskandar; Taty Hernawaty
Jurnal Kesehatan Bakti Tunas Husada: Jurnal Ilmu-ilmu Keperawatan, Analis Kesehatan dan Farmasi Vol 20, No 2 (2020)
Publisher : LPPM Universitas Bakti Tunas Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36465/jkbth.v20i2.612

Abstract

CORRELATION BETWEEN COGNITIVE FUNCTION AND SERUM LEVELS OF TUMOR NECROSIS ALPHA (TNF-α) IN SCHIZOPHRENIA Eldi Sauma; Antania Hanjani Irianti; Tuti Kurnianingsih; Shelly Iskandar; Sumartini Dewi; Veranita Pandia
Majalah Kedokteran Andalas Vol 46, No 8 (2024): Online Januari 2024
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i8.p1261-1270.2024

Abstract

Introduction: Impaired cognitive function causes significant impairment in schizophrenic patients. Studies result found that inflammatory processes in the brain play an important role in cognitive decline in schizophrenia. One of the inflammatory markers associated with cognitive function in schizophrenia is serum Tumor Necrosis Factor Alpha (TNF-α) levels. TNF-α levels can be influenced by genetic and racial factors.   Objective: This study aims to analyze the correlation between cognitive function and TNF-α serum levels in schizophrenic patients in Indonesia. Methods: This study is an analytical study using a cross-sectional design in 34 schizophrenic patients who were hospitalized in the Mental Hospital of West Java Province. Patients with risk of inflammation and cognitive impairment are excluded. Cognitive function was assessed using the Rey Auditory Verbal Learning Test (RAVLT), Digit Span and Trail Making Test. TNF-α serum levels were measured using the Sandwitch-ELISA (Enzyme-linked Immunosorbent Assay) method. Results: Study participants showed a cognitive deficit in all examination instruments. The TNF-α serum levels of the participants increased (mean: 8.93 ± 3.43). TNF-α serum levels was not significantly correlated with cognitive function. Conclusion: There is no significant correlation exist between cognitive function and TNF-α serum levels in schizophrenia.Keywords: Schizophrenia, cognitive function, TNF-α
THE ROLE OF SLEEP IN INFANT AND EARLY CHILDHOOD COGNITIVE DEVELOPMENT: A SCOPING REVIEW Martin, Novia; Mose, Johanes Cornelius; Iskandar, Shelly
Media Penelitian dan Pengembangan Kesehatan Vol. 34 No. 2 (2024): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v34i2.2061

Abstract

Tidur adalah periode terjadinya perubahan aktivitas otak, berkurangnya aktivitas sensorik dan daya tanggap terhadap rangsangan eksternal. Penelitian telah membuktikan banyaknya manfaat tidur bayi dan balita terhadap perkembangan kognitif serta dampaknya pada anak usia sekolah. Bayi yang memiliki pengaturan tidur yang baik diyakini memberikan dampak positif pada kemampuan kognitif. Sebaliknya, gangguan tidur pada masa kanak-kanak berhubungan dengan volume otak yang lebih kecil. Bukti dalam 20 tahun terakhir menunjukkan bahwa tidur sangat penting untuk perkembangan sistem sensorik pada janin dan bayi, menjaga plastisitas otak, penciptaan memori dan pembelajaran jangka Panjang. Oleh karena itu, scoping review ini bertujuan mengidentifikasi bukti yang tersedia tentang peran tidur pada bayi dan balita terhadap perkembangan kognitifnya. Pencarian sistematis dilakukan di PubMED, ScienceDirect, SCOPUS, The Lancet, dan Oxford Academic Journal dengan menggunakan istilah dan kata kunci yang telah ditentukan. Artikel yang dijadikan rujukan adalah artikel yang publish pada 10 tahun terakhir, berbahasa inggris, merupakan artikel penelitian, dan dapat diakses, sedangkan artikel yang berupa buku, tesis, surat, review dikecualikan. Dari hasil seleksi diperoleh total akhir 7 artikel untuk di review. Hasilnya, tidur memiliki banyak manfaat bagi perkembangan kognitif bayi dan balita yakni mereka dengan tidur yang cukup memiliki kemampuan memperhatikan, memproses, dan berkomunikasi dengan lebih baik dibandingkan mereka yang tidak cukup tidur. Diperlukan adanya penelitian lebih lanjut mengingat keterbatasan dari sebuah tinjauan sistematis yakni rentan terhadap bias dalam seleksi artikel dan heterogenitas statistik.
Studi Literatur: Predisposing, Enabling, dan Reinforcing Factors Terjadinya Perilaku Seksual Pranikah pada Remaja: PREDISPOSING FACTORS, ENABLING FACTORS, DAN REINFORCING FACTOR TERJADINYA PERILAKU SEKSUAL PRANIKAH PADA REMAJA : LITERATUR REVIEW Hardiyati Hardiyati; Shelly Iskandar; Taty Hernawaty
Jurnal Kesehatan Manarang Vol 5 No 2 (2019): Desember 2019
Publisher : Politeknik Kesehatan Kemenkes Mamuju

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (280.062 KB) | DOI: 10.33490/jkm.v5i2.106

Abstract

Adolescent behaviors that have the potential to cause problems that often occur and are most prominent among adolescents are some high-risk behaviors including experiences of sexual violence and premarital sexual behavior. Changes that occur in adolescents ranging from physical, psychological, and social changes that risk causing problems because they are hanging out with peers and feel attracted to the opposite sex. The impact of sexual behavior on adolescents results in abortion, unwanted pregnancy, death, increased incidence of HIV/AIDS as well as an increase in juvenile crime in adolescents. The purpose of this literature study is to identify early predisposing factors, enabling factors, and reinforcing factors that influence premarital sexual behavior. The method used in writing this literature study with internet searches from Proquest, CINAHL, EBSCOHost, Pubmed, Google Scholar and nursing books from 2000 – 2014 with the keywords Premarital sexual behavior. Predisposing factors include dating status, dating frequency, and knowledge. Enabling factors include the use of smartphones and reinforcing factors are religious norms and family norms. It can be concluded that several factors that influence the occurrence of premarital sexual behavior include dating status, frequency of dating, knowledge, smartphone usage, religious norms and family norms. The high influence of premarital sexual behavior shows that health promotion programs must be focused on increasing positive and supportive values, as well as the need for skills training so that adolescents can avoid premarital sexual behavior.
Hatha Yoga vs Prenatal gymnastic: The Perfect Choice to Reduce Stress and Improve Health for Primigravid Fernandez, Veronica; Lesmana, Ronny; Krisnadi, Sofie Riyani; Susiarno, Hadi; Tarawan, Vita Murniati; Iskandar, Shelly
JURNAL KEBIDANAN Vol 15, No 1 (2025): April 2025
Publisher : Politeknik Kesehatan Kementerian Kesehatan Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jkb.v15i1.12677

Abstract

Abstract: Pregnancy is a critical period involving significant physiological and psychological changes, particularly in primigravida women who are more susceptible to anxiety and stress. Elevated stress levels during pregnancy may increase the risk of complications like high blood pressure, preeclampsia, and premature delivery. Non-pharmacological interventions like Hatha Yoga and gymnastic prenatalhave been widely recommended to improve maternal well-being. The purpose of this research was to evaluate and compare the impacts of two different interventions on maternal psychological and physiological health through a Systematic Literature Review (SLR) conducted in accordance with PRISMA guidelines. Relevant literature was retrieved from databases including Pubmed, Scopus, ScinceDirect, Google Scholar, focusing on research published between 2014 and 2024. The findings indicate that Hatha Yoga is more effective in reducing anxiety, cortisol levels, and systolic blood pressure, while prenatal gymnastic better supported diastolic blood pressure regulation and physical endurance for labor. Both interventions contribute to better cardiovascular function, increased oxygen saturation, and a smoother labor process. Additionally, yoga is associated with improved neonatal outcomes, while studies on prenatal exercise’s effects on newborn health remain limited. Future research should explore the long-term effects and key differences between these interventions to determine the most effective approach for maternal and neonatal health. These findings support integrating yoga and gymnastic prenatalinto antenatal care programs to enhance pregnancy outcomes.
Co-Authors Achadiyani Adityana Sulistyo Agraini Agraini AJENG DIANTINI Ajeng Fitria Ambrosius Purba Ambrosius Purba Amri, M Faizal Antania Hanjani Irianti Arjon Turnip Bambang Eryanto Danasasmita, Febrianti Santiardi Dewi, Sumartini Dhanasari Vidiawati Dwi Agustian efri widianti Eka Puji Lestari Elda Nazriati Eldi Sauma Erwin Sumardi Fedri Rinawan Fernandez, Veronica Fidella Fidella Fitri N. Ramadhani Fitria, Nita Francisca Nungki Triandari Hardiyati Hardiyati Hertini, Reni Imas Rafiyah Irfan I Irianti, Antania Hanjani Johanes C. Mose Kartika Farahdilla Fitri Kevin Sulay Wijaya Khairiyatul Munawwarah Krisnadi, Sofie Riyani Kurnianingsih, Tuti Kusumandari, Dwi Esti Leonardo Lubis Leonardo Lubis Lydyana, Lynna Lynna Lidyana Lynna Lidyana Martin, Novia Melisa I. Barliana Melisa Intan Barliana, Melisa Intan Mohammad Ghozali Nadiya, Ulfah Nita Fitria Paramitha Kusuma Primal Sudjana Priskila Gracianita Rahmawati, Annida Reni Hertini Rio Dananjaya Ronny Lesmana Rudi Wisaksana Simbolon, Artha Ivonita Siti Aminah Sobana Sofie R. Krisnadi Sumartini Dewi Susiarno, Hadi Syahrina, Nadira Alvi Taty Hernawaty Taty Hernawaty Taty Hernawaty Taty Hernawaty Theresia Dewi Tuti Kurnianingsih Tuti Kurnianingsih Veranita Pandia Veranita Pandia Veranita Pandia Vita Muniarti Tarawan Vita Murniati Tarawan Wibowo, Jony Winaryo Winda Kurniati Zakiyah, Neily