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Tromboemboli Dalam Kehamilan: Sebuah Tinjauan Pustaka Laksono, Sidhi; Sakura, Ayumi Syifa
Berkala Ilmiah Kedokteran dan Kesehatan Masyarakat Vol. 3 No. 2 (2025)
Publisher : Fakultas Kedokteran, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/bikkm.vol3.iss2.art14

Abstract

Venous Thromboembolism (VTE) menyebabkan mortalitas dan morbiditas pada ibu hamil dan postpartum. Kehamilan meningkatkan risiko penyebab VTE sampai empat hingga lima kali dibandingkan pada wanita yang tidak hamil dan risiko akan meningkat 30 sampai 60 kali pada postpartum. VTE terdiri dari dua bentuk utama, yaitu deep vein thrombosis (DVT) dan pulmonary embolism (PE). Patofisiologi VTE dijelaskan melalui triad Virchow: stasis vena, kerusakan endotel, dan hiperkoagulabilitas. Manifestasi klinis VTE pada kehamilan menyerupai fisiologis kehamilan sehingga dilakukan pemeriksaan diagnosis untuk mendiagnosa VTE, pemeriksaan diagnosis dilakukan menggunakan alat diagnostik yang aman untuk ibu hamil dan janin. Antikoagulan dapat diberikan untuk terapi sejak VTE terdiagnosa. VTE. Studi ini menjelaskan mengenai tromboembolisme pada kehamilan yang mencakup faktor risiko, patofisiologi, diagnosis dan terapi pada wanita hamil dan wanita pasca melahirkan. Kata Kunci: Deep Vein Thrombosis (DVT); Pulmonary Embolism (PE); Tromboembolisme (VTE)
Karakteristik Klinis dan Demografi Pasien Infark Miokard Elevasi ST di Siloam Heart Center: A Single Center Study Laksono, Sidhi; Nurbaeti, Putri
Majalah Kedokteran Indonesia Vol 75 No 3 (2025): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.75.3-2025-1887

Abstract

Introduction: Cardiovascular disease remains the leading cause of death globally, with ST-elevation myocardial infarction (STEMI) posing the highest mortality among acute coronary syndromes (ACS). Early intervention, such as percutaneous coronary intervention (PCI), improves outcomes. Objective: To describe the clinical and demographic profile of STEMI patients in Indonesia and identify risk factors associated with disease severity.Methods: A retrospective descriptive study was conducted on STEMI patients who underwent PCI at a Heart Center Hospital from January to December 2024. Data from electronic medical records were analyzed, including only confirmed STEMI cases with complete documentation.Result: 87 patients were included, most male (92%) and aged over 50 (66.7%). Hypertension (49.4%), smoking (46%), and diabetes mellitus (27.6%) were common comorbidities. Leukocytosis occurred in 86.2%, with universally elevated troponin levels. Despite frequent cardiomegaly on chest X-rays, 46% had preserved ejection fraction on echocardiography. Inferior (34.5%) and anterior (19.5%, 17.2%) infarctions were the most common ECG findings. The left anterior descending (LAD) artery was affected in 85.1%, with three-vessel disease present in 49.4%. Mean door-to-balloon (DTB) time was 86.25 minutes. In Intra-PCI Complications, dissection in 2.3%.Conclusion: STEMI in Indonesia predominantly affects older males with modifiable cardiovascular risk factors. These factors are closely linked to severe coronary involvement, particularly multi-vessel disease.
PCI Revascularization Strategies in Patients with Acute Myocardial Infarction and Multivessel Disease Laksono, Sidhi; Widyani, Wella
Medical and Health Journal Vol 5 No 1 (2025): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2025.5.1.16915

Abstract

Background: The incidence of Acute Myocardial Infarction (AMI) accompanied by Multivessel Disease (MVD) has increased annually, necessitating appropriate revascularization strategies to minimize clinical risks. Objective: This study aimed to evaluate various revascularization strategies using Percutaneous Coronary Intervention (PCI) that can be applied in patients with AMI and MVD. Methods: A systematic review was conducted using the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) method. The keywords used were (“Revascularization" AND "Multivessel Disease" AND "Acute Coronary Syndrome”) OR (“Revascularization" AND "Multivessel Disease" AND "Acute Myocardial Infarction”). Articles were collected based on inclusion criteria: original articles, published in English, and published between 2020 and 2025. Results: A total of 1,263 articles were found in the initial search. Of these, 169 were excluded due to duplication, 1,069 due to irrelevant PICO criteria, and 6 due to limited access. From the remaining 19 articles, it was found that revascularization strategies could be classified based on the number of vessels treated (culprit-only, incomplete, and complete revascularization) and the timing of the intervention (immediate and staged revascularization). Conclusion: No single strategy was superior in all contexts. The choice of revascularization strategy should be individualized based on each patient’s clinical status and coronary anatomy to optimize outcomes.
COMPLICATIONS SURVEY OF PERCUTANEOUS CORONARY INTERVENTION: A CROSS-SECTIONAL STUDY Laksono, Sidhi; Kusharsamita, Hillary
Biomedika Vol 17, No 1 (2025): Biomedika August 2025
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v17i2.3327

Abstract

The purpose of this research is to examine the perspectives of interventional cardiologists, and the annual incidence of each PCI complications. This study is based on a cross-sectional analysis conducted using the Google Forms. The technique for determining the research subject used in this study was non-random sampling with purposive sampling technique. The anonymity and confidentiality of the information collected is highly prioritized. Annual PCI incidence rates are as follows: 100 (13%) 100–199 (13%), 200–299 (35%) 300 and above (38%). With a mean score of 5.56 on a scale from 0 to 10, participants are very concerned about the possibility of PCI complications. Coronary perforation is the most concerning complication of PCI (83%). Annually, coronary artery dissection occurred between once and five times (73%), coronary perforation occurred between once and five times (50%), and hemodynamic collapse was occurred at one to five times (60.9%). Further, 78.3% of participants never used covered stents, while 32% of participants used balloon tamponade at least one to five times each year. Participating interventional cardiologists in our research have concerns about possible PCI complications. Perforations, dissections, hemodynamic collapse, no-reflow, and entrapment equipment are complications that operators must be ready to identify and control.
Building Bridges in Cardio-Oncology: The Role of Clinics in Multidisciplinary Care and Patient Outcomes Laksono, Sidhi
Indonesian Journal of Cancer Vol 19, No 3 (2025): September
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i3.1299

Abstract

Cardio-oncology is a specialized field within cardiology that focuses on the relationship between cancer, its therapies, and cardiovascular health. This multidisciplinary domain, involving cardiology, hematology, and oncology, addresses the significant cardiovascular risks associated with cancer treatments, particularly chemotherapy, which can lead to conditions such as heart failure, coronary artery disease, myocarditis, and pericardial effusion. Developing robust clinical pathways is essential to mitigate these risks and ensure timely diagnosis and management of therapy-induced cardiac dysfunction. Cardio-oncology clinics play a pivotal role in integrating multidisciplinary expertise, providing consultation and heart evaluation services, and fostering research to improve patient outcomes. Strengthening collaboration across disciplines and raising awareness among patients are critical goals in advancing the effectiveness of cardio-oncology clinics.
Intervensi Transkateter Katup Aorta Menggunakan Edwards Sapien 3 Pada Perempuan 70 Tahun Dengan Stenosis Aorta Berat: Laporan Kasus Laksono, Sidhi; Widyani, Wella
Jurnal Medika Malahayati Vol 9, No 3 (2025): Volume 9 Nomor 3
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jmm.v9i3.17536

Abstract

Implantasi transkateter katup aorta (TAVI) merupakan pilihan terapi selain bedah pada pasien stenosis aorta (AS) berat dengan risiko bedah yang sedang-tinggi. Tindakan TAVI ini efektif aman dikerjakan pada pasien usia tua dengan AS berat. Kasus perempuan 70 tahun dengan keluhan cepat lelah ketika berenang yang dirasakan sejak 3 bulan yang lalu, pasien ini dengan gangguan katup AS berat serta memiliki faktor risiko hipertensi dan diabetes melitus tipe 2. Dari hasil pemeriksaan echo dan CT aorta disarankan untuk tindakan penggantian katup baik secara bedah atau transkateter, pasien memilih untuk tindakan transkateter. Dilakukanlah pemasangan TAVI Edward Sapien 3 ukuran 20mm dengan hasil baik.  Seperti yang ditunjukkan oleh kasus klinis ini, TAVI telah terbukti menjadi pengobatan yang efektif pada pasien dengan stenosis aorta dan risiko bedah menengah.
Distinguish Between Perforation or Coronary Cameral Fistula: A Rare Findings during Percutaneous Coronary Intervention Laksono, Sidhi; Angkasa, Irwan Surya; Zheng, Tonni; Hosana, Cliffian; Nurbaeti, Putri; Nokik Stujanna, Endin
The Avicenna Medical Journal Vol. 6 No. 1 (2025): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v6i1.45801

Abstract

Introduction: Coronary cameral fistula (CCFs) is a connection between the coronary arteries and a chamber of the heart. Most of it is accidentally found on coronary angiography. This case report discusses a patient with symptoms in whom CCF was incidentally found on CAG. Case presentation: A 49-year-old male patient came to our hospital to undergo an elective standby coronary angiogram. No plaque was found in the LM and LCx; however, a chronic total occlusion (CTO) in the medial LAD was found, as well as 60% tubular stenosis in the proximal and 75% tubular stenosis in the distal RCA. Drug eluting stent was placed up to 20 atm in mid-distal LAD. However, we found contrast-dye extravasation that emptied directly into the heart chamber from the distal LAD. There’s no any signs of pericardial effusion from the bedside echo thus reinforcing the diagnosis of CCFs. Discussion: CCFs represent rare cardiovascular anomalies characterized by abnormal connections between coronary arteries and cardiac chambers or major vessels. Conclussion: Bedside echocardiography is a rapid modality to differentiate perforation from CCFs and can be performed intra-PCI. Management such as transcatheter closure or surgical ligation, can be performed with their own indications.
Artificial Intelligence dan Kardiologi: A Mini Review Laksono, Sidhi; Candra, Wincent
Health and Medical Journal Vol 4, No 2 (2022): HEME May 2022
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (153.619 KB) | DOI: 10.33854/heme.v4i2.964

Abstract

Dalam diagnosis dan terapi pasien dengan gangguan jantung masih terdapat keterbatasan-keterbatasan tertentu. Teknologi medis berbasis artificial intelligence berkembang dengan pesat sebagai solusi yang dapat diterapkan untuk praktik klinis. Artificial intelligence sendiri merupakan istilah yang digunakan dalam pemanfaatan teknologi dan komputer untuk mensimulasikan perilaku cerdas dan pemikiran kritis yang sebanding dengan manusia. Saat ini, hanya pengaturan tertentu dalam praktik klinis yang mendapat manfaat dari penerapan artificial intelligence. Artificial intelligence menawarkan solusi akan beberapa permasalahan pada kardiologi. Artificial intelligence berpotensi meningkatkan kualitas pelayanan kedokteran pada bidang kardiologi. Perlu adanya standar tertentu dalam manajemen kedokteran berbasis artificial intelligence.
Tatalaksana Angina Pektoris Stabil pada Pasien Dewasa Tua : Literature Review Laksono, Sidhi; Surya Angkasa, Irwan
GALENICAL : Jurnal Kedokteran dan Kesehatan Mahasiswa Malikussaleh Vol. 4 No. 5 (2025): GALENICAL : Jurnal Kedokteran dan Kesehatan Mahasiswa Malikussaleh - Oktober 20
Publisher : Program Studi Kedokteran Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/jkkmm.v4i5.17876

Abstract

Prevalensi penyakit jantung di Indonesia berdasarkan data Riskesdas 2018 masih cukup tinggi sebesar 1.5% atau sekitar 2.784.064 individu. Dimana 4 dari 5 kematian akibat penyakit jantung disebabkan oleh stroke dan penyakit jantung koroner. Morbiditas dan mortalias cenderung meningkat pada pasien berusia lanjut karena biasanya pasien lanjut usia disertai dengan penyakit komorbid seperti hipertensi, dan diabetes. Beberapa obat anti-angina juga dapat memberikan efek yang tidak diinginkan. Penentuan terapi baik dengan obat maupun intervensi yang tepat sangat membantu dokter untuk mendapatkan hasil terapi terbaik bagi pasien lanjut usia. Penulisan ini bertujuan untuk merangkum penelitian-penelitian serta guideline pilihan terapi bagi pasien usia lanjut yang mengalami angina pektoris stabil.
CARDIORENAL SYNDROME: NARRATIVE REVIEW Laksono, Sidhi; Nugraha, Dhiki
Al-Iqra Medical Journal : Jurnal Berkala Ilmiah Kedokteran Vol. 6 No. 2 (2023): Al-Iqra Medical Journal: Jurnal Berkala Ilmiah Kedokteran
Publisher : Journal Medical Universitas muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26618/aimj.v6i2.9732

Abstract

Cardiorenal syndrome is a disorder that involves the heart and kidneys, acute or chronic dysfunction of one organ can induce acute or chronic dysfunction of other organs. Renal dysfunction associated with acute heart failure, and vice versa, causes considerable morbidity and mortality. Until recently, there has been no consistent and effective strategy in the management of patients with cardiorenal syndrome. Generally, only done by reducing the volume of fluid so as not to worsen kidney function. Early identification leads to more effective treatment and shorter hospitalization. A multidisciplinary approach involving cardiologists and renal specialists is essential.