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Prevalensi Pelvic Inflammatory Disease Akibat Infeksi Menular Seksual (Non-HIV) pada Perempuan Indonesia: Studi Berbasis GBD 2023 Asyifa Tsulus Sandi; Sani Rachman Soleman; Vita Widyasari
Jurnal Medical Laboratory Vol. 5 No. 2 (2026): Juli: Jurnal Medical Laboratory
Publisher : Sekolah Tinggi Ilmu Kesehatan Kesetiakawanan Sosial Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/medlab.v5i2.570

Abstract

Pelvic Inflammatory Disease (PID) is an inflammatory syndrome of the female upper genital tract that is primarily caused by non-HIV sexually transmitted infections (STIs), such as Chlamydia trachomatis and Neisseria gonorrhoeae, and may lead to infertility, ectopic pregnancy, and chronic pelvic pain if not adequately treated. Epidemiological data on PID at the population level in Indonesia remain very limited. This study aimed to describe the prevalence trend of PID caused by non-HIV STIs among females of all ages in Indonesia during the 2021–2023 period using data from the Global Burden of Disease (GBD) 2023. This descriptive study used secondary data downloaded from the GBD Results Tool (Institute for Health Metrics and Evaluation/IHME). The analyzed measure was the prevalence rate (per 100,000 population) among females of all ages in Indonesia, with non-HIV STIs as the cause and PID as the outcome, for the years 2021, 2022, and 2023, accompanied by 95% uncertainty intervals (UI). The prevalence rate of PID caused by non-HIV STIs among Indonesian females was recorded at 7.05 (95% UI 5.40–9.23) per 100,000 population in 2021, remained relatively stable at 7.04 (95% UI 5.35–9.25) per 100,000 in 2022, and then increased to 8.16 (95% UI 5.77–11.13) per 100,000 in 2023—equivalent to an increase of approximately 15.8% compared to the previous year. In conclusion, there was a tendency toward an increasing prevalence of PID caused by non-HIV STIs among Indonesian females in 2023, although the uncertainty intervals of the estimates remained relatively wide, requiring cautious interpretation. These findings indicate the importance of strengthening STI screening and management in primary healthcare facilities (PHCs) as an effort to prevent PID.
Tren Prevalensi dan Beban Disabilitas (DALY) Skizofrenia di Indonesia Sebelum dan Pasca Pandemi COVID-19: Analisis Data Global Burden of Disease 2020–2023 Luna Litami; Titik Kuntari; Vita Widyasari
Jurnal Medical Laboratory Vol. 5 No. 2 (2026): Juli: Jurnal Medical Laboratory
Publisher : Sekolah Tinggi Ilmu Kesehatan Kesetiakawanan Sosial Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/medlab.v5i2.571

Abstract

Schizophrenia is a severe chronic mental disorder that contributes substantially to the overall disability burden at the population level. This study aimed to analyze trends in the prevalence and disability burden of schizophrenia in Indonesia before and after the COVID-19 pandemic using Disability-Adjusted Life Years (DALYs) as the main indicator. This research employed a quantitative observational design with an analytic descriptive approach, utilizing secondary data from the Global Burden of Disease (GBD) database for the period 2020–2023. The analysis included age-standardized estimates of schizophrenia prevalence and DALYs across 34 provinces in Indonesia. Statistical analyses consisted of descriptive analysis, Pearson correlation tests, and paired samples t-tests to assess year-to-year differences. The results demonstrated a small but consistent and statistically significant increase in schizophrenia prevalence throughout the study period. A parallel and significant increase in DALYs was also observed. A very strong correlation between prevalence and DALYs was found across all years, indicating that increases in prevalence were closely associated with higher disability burden. Significant differences in both prevalence and DALYs were identified between the pre- and post-COVID-19 pandemic periods, suggesting a sustained impact of the pandemic on schizophrenia burden. In conclusion, schizophrenia remains a persistent public mental health challenge in Indonesia, with an increasing disability burden over time. These findings highlight the need for strengthened mental health policies, improved access to continuous treatment, and expanded psychosocial rehabilitation services to mitigate long-term disability associated with schizophrenia.  
Tren Prevalensi dan YLD Stroke di Indonesia Tahun 2021-2023: Analisis Data Global Gurden of Disease Yuni Asnaini; Titik Kuntari; Vita Widyasari
Jurnal Medical Laboratory Vol. 5 No. 2 (2026): Juli: Jurnal Medical Laboratory
Publisher : Sekolah Tinggi Ilmu Kesehatan Kesetiakawanan Sosial Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/medlab.v5i2.572

Abstract

Stroke is one of the non-communicable diseases that remains a leading cause of mortality and disability worldwide, including in Indonesia. The increasing prevalence of stroke and the high number of Years Lived with Disability (YLD) indicate the substantial health burden caused by this disease. This study aimed to analyze the trends in stroke prevalence and YLD in Indonesia during the period 2021–2023 based on data from the Global Burden of Disease (GBD). This research employed a quantitative descriptive method with an ecological approach and time-trend analysis. Secondary data were obtained from the GBD Results Tool platform and analyzed using R software version 4.4.1. The analysis was conducted based on geographical regions, particularly across the major islands of Indonesia. The results showed that both stroke prevalence and YLD gradually increased during the 2021–2023 period. Java Island recorded the highest prevalence and YLD compared to other regions, while Maluku and Papua exhibited lower prevalence but greater variation in YLD. The increase in prevalence and YLD was associated with high urbanization, unhealthy lifestyles, hypertension, diabetes, and unequal access to healthcare and rehabilitation services. Pearson correlation analysis demonstrated a very strong relationship between stroke prevalence and YLD in each study year (r > 0.99). In addition, significant regional differences were identified in the distribution of stroke prevalence and YLD. This study concludes that the burden of stroke in Indonesia continues to increase and demonstrates regional disparities. Therefore, health policies should focus more on controlling major risk factors, improving equitable access to healthcare services, and strengthening post-stroke rehabilitation programs to reduce disability caused by stroke in Indonesia.
The Impact of GNI per Capita on the Prevalence and Incidence of Anxiety and Depressive Disorders: A Global Analysis Using GBD 2023 Data Dede Efendy; Utami Utami; Vita Widyasari; Yoga Saputra; Yuni Asnaini
Jurnal Medical Laboratory Vol. 5 No. 2 (2026): Juli: Jurnal Medical Laboratory
Publisher : Sekolah Tinggi Ilmu Kesehatan Kesetiakawanan Sosial Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/medlab.v5i2.573

Abstract

Mental health disorders, particularly depression and anxiety, continue to contribute significantly to the global burden of disease and disability. Socioeconomic inequality, especially differences in Gross National Income (GNI) per capita, is considered an important determinant influencing mental health outcomes across countries and regions. This study aimed to analyze the relationship between GNI per capita and the prevalence of depression and anxiety disorders globally using data from the Global Burden of Disease (GBD) 2023 database. A descriptive ecological study design was employed using secondary data from 187 countries and regions. Data were analyzed using descriptive statistics, Spearman correlation analysis, and regional comparative analysis with ANOVA. The findings demonstrated substantial regional disparities in mental health burden and income distribution. Africa showed the highest average prevalence of depression, while Asia exhibited the greatest variability in anxiety disorders. A statistically significant negative correlation was found between depression and income levels (r = -0.213; p = 0.003), indicating that lower-income countries tend to experience higher levels of depression. In contrast, the relationship between anxiety and income was weak and not statistically significant (r = -0.079; p = 0.281), suggesting that anxiety disorders may also be influenced by social, cultural, and structural factors beyond economic conditions. Significant regional differences were also identified for both depression and income levels. These findings highlight the importance of addressing socioeconomic inequalities and strengthening mental health systems, particularly in low- and middle-income countries. Integrating mental health services into primary healthcare and implementing multisectoral policies that combine economic development, social protection, and accessible healthcare are essential strategies for reducing the global burden of mental disorders and improving population well-being.  
Perbandingan Prevalensi dan Kematian Ileus Paralitik dengan Kanker Usus Besar di Indonesia: Analisis Data Global Burden of Disease (GBD) Tahun 2019, 2021 dan 2023 Irma Nurvita Zerlinda; Vita Widyasari; Titik Kuntari
Jurnal Medical Laboratory Vol. 5 No. 2 (2026): Juli: Jurnal Medical Laboratory
Publisher : Sekolah Tinggi Ilmu Kesehatan Kesetiakawanan Sosial Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/medlab.v5i2.574

Abstract

Colorectal cancer and paralytic ileus are significant health concerns worldwide, including in Indonesia, where their prevalence and mortality rates have shown concerning trends. This study aims to compare the prevalence and mortality of paralytic ileus and colorectal cancer in Indonesia using data from the Global Burden of Disease (GBD) for the years 2019, 2021, and 2023. A secondary data analysis was conducted using GBD 2023 data, focusing on prevalence, incidence, and mortality rates for both conditions across 34 provinces in Indonesia. The study employed a time-trend analysis to observe the changes in disease burden over the specified years, along with examining the differences in disease characteristics based on sex, age groups, and regions. Results indicated that colorectal cancer has a higher burden of disease, with significantly higher prevalence and mortality rates compared to paralytic ileus. This highlights the urgent need for enhanced prevention, early detection, and management strategies for colorectal cancer in Indonesia. The findings emphasize the importance of integrated healthcare policies to address both conditions effectively, focusing on regions with the highest disease burden. Further research is recommended to explore the underlying risk factors and to evaluate the effectiveness of current healthcare interventions.
Trends in Ischemic Heart Disease in Indonesia from 2019–2023: A Global Burden of Disease-Based Study with Gender Analysis (Male and Female) Rizka Triadiati Ikhsantiningtyas Pratisti; Utami Utami; Vita Widyasari
Jurnal Medical Laboratory Vol. 5 No. 2 (2026): Juli: Jurnal Medical Laboratory
Publisher : Sekolah Tinggi Ilmu Kesehatan Kesetiakawanan Sosial Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/medlab.v5i2.575

Abstract

This study aims to analyze the trends in the prevalence of ischemic heart disease (IHD) in Indonesia from 2019 to 2023 based on data from the Global Burden of Disease (GBD) study, with a focus on gender differences between males and females. The data used in this study includes detailed prevalence data for IHD based on province and gender. The analysis reveals that the prevalence of IHD is higher in males than in females, with greater fluctuations observed in females, particularly after menopause. Although there are significant differences in the prevalence across several provinces, risk factors such as smoking, obesity, hypertension, and diabetes contribute significantly to the increasing prevalence of this disease. However, the differences in prevalence between provinces and genders are not always statistically significant, indicating that other factors such as access to healthcare, lifestyle, and socio-economic factors also influence the distribution of this disease. This study provides valuable insights for the development of gender-based heart disease prevention policies and introduces more targeted interventions.
Analisis Beban Kecelakaan Sepeda Motor di Pulau Jawa: (Studi Epidemiologi Insidensi, Mortalitas, dan Years Lived with Disability (YLD) pada Rentang Usia 10-49 Tahun (Data GBD tahun 2023)) Dadan Andriyanto; Sunarto Sunarto; Vita Widyasari
Jurnal Medical Laboratory Vol. 5 No. 2 (2026): Juli: Jurnal Medical Laboratory
Publisher : Sekolah Tinggi Ilmu Kesehatan Kesetiakawanan Sosial Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/medlab.v5i2.592

Abstract

Motorcycle-related Road injuries remain one of the leading causes of morbidity, mortality, and disability among the productive-age population in Indonesia, particularly on Java Island. This study aimed to analyze the burden of motorcycle-related injuries using the indicators of incidence, mortality, and Years Lived with Disability (YLD) among individuals aged 10–49 years across six provinces on Java Island in 2023. A descriptive ecological study design was employed using secondary data obtained from the 2023 Global Burden of disease (GBD) database managed by the Institute for Health Metrics and Evaluation (IHME). Descriptive analyses were conducted on age- and province-specific incidence, mortality, and YLD rates per 100,000 population. The findings revealed substantial interprovincial variations in the burden of motorcycle injuries. The Special Region of Yogyakarta recorded the highest Incidence and YLD rates, whereas West Java and East Java exhibited relatively higher mortality rates in specific age groups. Individuals aged 15–24 years experienced the highest Incidence and mortality, while YLD increased progressively with age, peaking among those aged 45–49 years. These findings highlight the need for age-specific road safety strategies, emphasizing primary prevention for younger riders and strengthened rehabilitation services to reduce long-term disability among the productive-age population.