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All Journal ThufuLA: Jurnal Inovasi Pendidikan Guru Raudhatul Athfal Indonesian Journal of Pharmaceutical Science and Technology J-Dinamika: Jurnal Pengabdian Kepada Masyarakat Majalah Biomorfologi (Biomorphology Journal) Jurnal Pengabdian Masyarakat Jurnal Keperawatan Soedirman (The Soedirman Journal of Nursing)
Khaerunnisa, Siti
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Biochemistry, Genetics & Molecular Biology Computer Science & IT Education Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Peran Guru dalam Menanamkan Nilai Karakter Peduli Sosial Khaerunnisa, Siti; Muqowim, Muqowim
ThufuLA: Jurnal Inovasi Pendidikan Guru Raudhatul Athfal Vol 8, No 2 (2020): ThufuLA: Jurnal Inovasi Pendidikan Guru Raudhatul Athfal
Publisher : PIAUD IAIN Kudus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21043/thufula.v8i2.7636

Abstract

Tujuan penelitian ini yaitu untuk mengetahui peran guru dalam menanamkan nilai karakter peduli sosial di RA An Nawaa 3 Kota Cirebon. Penelitian ini dilatar belakangi oleh data hasil survey salah satu lembaga sosial di Indonesia yang menunjukkan bahwa kemampuan memiliki rasa empati pada anak muda menurun 40% selama 10 tahun terakhir, seiring dengan perkembangan teknologi dan internet. Penelitian ini menggunakan pendekatan deskriptif kualitatif. Beberapa informan yang dijadikan sumber data yaitu kepala sekolah, guru kelas B1, B2, B3, A1, dan A2. Hasil penelitian menunjukkan bahwa guru telah menjalankan perannya dalam menanamkan nilai karakter peduli sosial pada anak. Beberapa peran guru tersebut diantaranya guru sebagai sumber belajar, fasilitator, pengelola, demonstrator, pembimbing, motivator, evaluator, dan mediator. Faktor pendukungnya adalah antusias belajar anak yang tinggi, pelaksanaan program sekolah, dan dukungan dari orang tua murid. Sedangkan faktor penghambatnya yaitu emosi anak yang belum stabil dan adanya kendala pada waktu pelaksanaan program sekolah.
MOLECULAR DOCKING OF Crocus sativus PHYTOCHEMICALS AGAINST INDUCIBLE NITRIC OXIDE SYNTHASE AND PHOSPHODIESTERASE-9 IN HEART FAILURE PRESERVED EJECTION FRACTION Yasmine, Syafira; Firmanto, Neissya Nastiti; Sabrina, Annisa Maya; Khaerunnisa, Siti
Majalah Biomorfologi Vol. 33 No. 1 (2023): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v33i1.2023.20-29

Abstract

Highlights1. Heart failure preserved ejection fraction increases the mortality rate every year.2. Definitive therapy for HFpEF is not well identified.3. Crocus sativus phytochemical has anti-inflammatory and cardioprotective effects due to iNOS and PDE-9 inhibition. AbstractBackground: Heart failure preserved ejection fraction (HFpEF) is a complex disease associated with metabolic disease as a risk factor. A previous study found an association between iNOS and PDE-9 with inflammation and myocardial fibrosis in HFpEF. Objective: This study aimed to identify the potential phytochemicals of Crocus sativus (Saffron) that can inhibit protein iNOS and PDE-9 based on a molecular docking study. Material and Method: A total of fifty phytochemicals were obtained from Dr. Duke's Phytochemical Database and IJAH IPB. Those phytochemicals were screened by using the PyRx application and followed with Lipinski's Rule of Five screening by using SWISS Adme. Ten phytochemicals with lowest binding energy for each protein were docked and visually analyzed using Autodock 4.2 and BIOVIA Discovery Studio Visualizer 2016. Results: The best binding energy between protein-phytochemicals were -9.17 kcal/mol and -8.55 kcal/mol for iNOS and -9.17 kcal,/mol and -9.08 kcal/mol for PDE-9. Conclusion: Delphinidine and malvidin are the recommended inhibitors against iNOS and PDE-9 and must be investigated in further research.
Risk Factor Profile and Role of Cardiovascular Disease Outreach Program by Experts in Rural Communities: A Pilot Study in Magetan Regency, Indonesia Wungu, Citrawati Dyah Kencono; Elvaretta, Clarissa; Palupi, Dian Eka Roro; Qurnianingsih, Ema; Susilo, Hendri; Lukitasari, Lina; Humairah, Ira; Khaerunnisa, Siti; Soetjipto, Soetjipto; Handajani, Retno; Safitri, Indri; Ummah, Fithriyah Cholifatul; Waskito, Langgeng Agung; Prabowo, Gwenny Ichsan; Wiratama, Bayu Satria; Amin, Indah Binti Mohd
Jurnal Keperawatan Soedirman Vol 19 No 2 (2024): Jurnal Keperawatan Soedirman (JKS)
Publisher : Fakultas Ilmu-ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jks.2024.19.2.10947

Abstract

Cardiovascular outreach programs and risk factors profiling have been regarded as key strategy in preventing and controlling cardiovascular diseases as the leading global causes of death worldwide, especially when being conducted by a professional. This pilot study aims to evaluate the effectiveness of a cardiovascular outreach program in Plaosan District, Magetan Regency, to improve knowledge and influence changes in the community’s behavior related to cardiovascular risk factors. This study was conducted by providing educational interventions and profiling cardiovascular risk factors on 90 adults using consecutive sampling method. Health education was performed by experts and evaluated by pre-post tests before and after the material delivery. Statistical analysis was used to assess the relationship of risk factors that can contribute to cardiovascular disease. This study showed a significant increase in the participants' knowledge score after the intervention (p = 0.007). There were several risk factors for cardiovascular disease in the participants, with the highest risk prevalence being diabetes mellitus (33.33%). Six participants (6.67%) had abnormal electrocardiography results. In conclusion, our study showed a high prevalence of cardiovascular risk factors in rural communities and the importance of cardiovascular outreach programs by experts to improve the understanding of cardiovascular disease in a specific community.
Senyawa Non-aromatik Herba Centella asiatica menggunakan Metode Baru melalui Karbon Aktif, dan Analisis Farmakologi Jejaring pada Luka Bakar Awaluddin, Rizki; Mustaqim, Rafli Mulkan; Arbain, Dayar; Hayati, Farida; Khaerunnisa, Siti
Indonesian Journal of Pharmaceutical Science and Technology Vol 11, No 2 (2024)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v11i2.50623

Abstract

Prevalensi luka bakar masih menjadi perhatian kaitannya dengan perubahan fisik pasca luka bakar yakni contractures, hypertrophic scar dan keloid yang menurunkan fungsi, kualitas hidup dan estetika kulit. Herba pegagan (Centella asiatica) melalui senyawa triterpen telah dikenal untuk mempercepat luka bakar. Namun, sifat senyawa triterpen yang polar identik dengan keberadaan klorofil dan senyawa lainnya yang sulit dipisahkan. Masih adanya kontroversi terkait protein yang berperan dalam kesembuhan luka bakar membutuhkan kajian untuk menentukan protein potensial. Penelitian ini bertujuan untuk mengeksplorasi metode baru pada ekstraksi herba pegagan menggunakan karbon aktif serja kajian farmakologi jejaring untuk menentukan protein potensial. Herba pegagan diekstraksi menggunakan metode maserasi pada pelarut metanol dan dilanjutkan dengan penambahan karbon aktif. Hasil purifikasi diidentifikasi menggunakan KLT dengan fase gerak kloroform: asam asetat glasial: metanol: akuades (60:32:12:8 v/v) dan pereaksi semprot anisaldehid-asam sulfat. Kajian farmakologi jejaring dilakukan secara in silico untuk mengkaji interaksi protein-protein dan senyawa-protein berkaitan dengan luka bakar. Hasil skrining fitokimia menunjukkan keberadaan asaticoside pada ekstrak terpurifikasi dan maserat dengan nilai Rf yang relatif identik. Senyawa non aromatik berperan dalam mempercepat kesembuhan luka bakar dengan mempengaruhi protein IL1β, IL6, MAPK8, PTGS2, NOX4, IFN-γ, NFKB1, TGFβ1, MMP13, dan TNF.
Stop Bullying Counseling as an Effort to Prevent Bullying Behavior that Occurs in Students at Ketabang Seruni Elementary School Surabaya Fatimah, Nurmawati; Khairul Rizki Purba, Abdul; Fithriyah, Izzatul; Purwaningsih, Sri; Setiawati, Yuani; Khaerunnisa, Siti; Akbar Kurniawan, Mohammad
J-Dinamika : Jurnal Pengabdian Masyarakat Vol 9 No 3 (2024): Desember
Publisher : Politeknik Negeri Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The phenomenon of bullying is a serious problem for child development in Indonesia. Bullying cases in Indonesia are ranked fifth in Indonesia world in bullying incidents (Jayani, 2019). Violence against students at school is a topic of discussion mainstream in the media. The incidence of bullying is 10-60% of children who receive ridicule, ridicule, expulsion, kicking or pushing at least once a week. Cases of bullying in Children can occur anywhere, anytime and by anyone. This makes this case still high incidence rate (Komisi Perlindungan Anak Indonesia, 2020). If this bullying incident continues for a long time, it will have an impact on the victim of bullying, both physically, psychologically and socially. The bullying case at Ketabang Seruni Elementary School Surabaya is of particular concern to the school principal. During break time, students are often heard making fun of each other, and there are friends who are alone because they are ostracized. As a leading public school in the city of Surabaya, hopes that its students can be a good for other schools by implementing free bullying at schools. The solution offered to solve this problem is to provide education to students at Ketabang Seruni Elementary School Surabaya by providing an explanation first about the purpose of the activity, then giving a questionnaire to the students about various things related to the meaning of bullying, types of bullying, causes of bullying, characteristics of perpetrators and victims of bullying, bad impacts of bullying, prevention of bullying, efforts to handle bullying prevention. Education is provided by providing materials using powerpoint media, leaflets and posters which are pasted on the school walls as a means of reminder for the entire community at school, including students, teachers, employees and parents. The result of this activity is that there is an increase in students' understanding of bullying and good practices are obtained by changing the way students socialize to be better and more polite. Keywords — Mental health; Education; Discrimination; Dignity
KEGIATAN AKSI STOP STUNTING DI KAMPUNG RAWACANA KELURAHAN GANDASARI KOTA TANGERANG Swara, Marrieta Moddies; Nadya, Aisha; Nuraini, Hery; Romadhon, Ilham Qodry; Khaerunnisa, Siti
Abdi Pandawa: Jurnal Pengabdian Kepada Masyarakat Vol. 3 No. 2 (2023): Pengabdian Kepada Masyarakat
Publisher : Universitas Islam Syekh Yusuf Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33592/ap.v3i2.4216

Abstract

Stunting atau terhambatnya proses tumbuh kembang pada anak adalah masalah kesehatan global dimana memerlukan perhatian serius. Kegiatan Pengabdian Kepada Masyarakat di kampung Rawacana Kelurahan Gandasari Kota Tangerang menekankan pada peran kunci ibu dalam memastikan asupan gizi yang cukup selama kehamilan dan menyusui serta pengelolaan gizi dalam rumah tangga dimana mampu mendukung pertumbuhan anak. Diharapkan kegiatan Aksi Stop Stunting ini berguna bagi praktisi kesehatan, peneliti, dan masyarakat dalam upaya bersamaa pencegahan stunting untuk memastikan masa depan yang sehat bagi generasi mendatang. Langkah Aksi Stop Stunting ini harus diiringi dengan edukasi berkelanjutan, dukungan komunitas dan pemantauan pertumbuhan anak. Kata Kunci : Stunting, pertumbuhan, perkembangan, anak.
Co-Authors Abdul Khairul Rizki Purba Mustofa Indwiani Astuti Akbar Kurniawan, Mohammad Amin, Indah Binti Mohd Awaluddin, Rizki Bayu Satria Wiratama DAYAR ARBAIN Elvaretta, Clarissa Fatimah, Nurmawati Firmanto, Neissya Nastiti Hayati, Farida Hendri Susilo Humairah, Ira I'tishom, Reny Indri Safitri, Indri Izzatul Fithriyah Lukitasari, Lina Muqowim, Muqowim Mustaqim, Rafli Mulkan Nadya, Aisha Nuraini, Hery Palupi, Dian Eka Roro Prabowo, Gwenny Ichsan Qurnianingsih, Ema Retno Handajani Romadhon, Ilham Qodry Sabrina, Annisa Maya SOETJIPTO . Sri Purwaningsih Susanti, Nurul Fatimah Swara, Marrieta Moddies Ummah, Fithriyah Cholifatul Waskito, Langgeng Agung Wungu, Citrawati Dyah Kencono Yasmine, Syafira Yuani Setiawati