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All Journal Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) JCES (Journal of Character Education Society) JURNAL KESEHATAN PERINTIS Jurnal Farmasi Higea Jurnal Kesehatan Ilmiah Indonesia / Indonesian Health Scientific Journal Diseminasi : Jurnal Pengabdian kepada Masyarakat Jurnal Buana Farma Jurnal EduHealth Universitas Muhammadiyah Yogyakarta Undergraduate Conference Proceeding Farmasis: Jurnal Sains Farmasi Duta Pharma Journal Innovative: Journal Of Social Science Research Jurnal Pengabdian Kepada Masyarakat: Kesehatan (JPKMK) Jurnal Mahasiswa Ilmu Kesehatan JURNAL FARMASI DAN KESEHATAN INDONESIA Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Novena Adi Yuhara
Universitas Kristen Immanuel
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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PENETAPAN KADAR FLAVONOID TOTAL DAN UJI AKTIVITAS ANTIOKSIDAN INFUSA BUNGA KERTAS (Bougenvillea glabra) DENGAN SPEKTROFOTOMETER UV-Vis Rawar, Ellsya; Charis, Jesisca; Adi Yuhara, Novena
Duta Pharma Journal Vol. 5 No. 2 (2025): Duta Pharma Journal
Publisher : Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/whnsee23

Abstract

Latar Belakang : Pola makan yang tidak sehat serta paparan stres dapat meningkatkan risiko penyakit degeneratif. Salah satu mekanismenya adalah stres oksidatif yang terjadi ketika jumlah radikal bebas dalam tubuh melebihi kapasitas antioksidan endogen. Flavonoid merupakan metabolit sekunder yang berperan sebagai antioksidan alami dan banyak ditemukan pada tumbuhan, termasuk bunga kertas (Bougainvillea glabra). Tujuan: Penelitian ini bertujuan untuk menentukan kadar flavonoid total serta nilai IC50 sebagai indikator aktivitas antioksidan infusa bunga kertas. Metode: Penelitian diawali dengan penyiapan simplisia melalui proses pengeringan dan penghalusan bunga, kemudian pembuatan infusa pada suhu 90 °C selama 15 menit. Identifikasi flavonoid dilakukan secara kualitatif menggunakan reagen spesifik. Penetapan kadar flavonoid total menggunakan metode kolorimetri dengan reagen AlCl? dan CH3COOK pada infusa 10% (10 g/100 mL). Aktivitas antioksidan diuji menggunakan metode DPPH untuk memperoleh nilai IC50. Hasil: Uji kualitatif menunjukkan adanya flavonoid yang ditandai dengan perubahan warna larutan menjadi jingga. Infusa bunga kertas 10% memiliki kadar flavonoid total sebesar 12,10±0,55 mgEK/10 g. Uji aktivitas antioksidan menunjukkan bahwa nilai IC?? infusa sebesar 703,34±12,37 µg/mL, yang mengindikasikan aktivitas antioksidan sangat lemah. Rendahnya aktivitas ini diduga terkait dengan kelarutan flavonoid yang kurang optimal dalam air serta kemungkinan degradasi senyawa pada pemanasan 90 °C. Kesimpulan: Infusa bunga kertas mengandung flavonoid, namun memiliki aktivitas antioksidan yang sangat lemah. Rendahnya kadar flavonoid terlarut dan potensi kerusakan senyawa akibat pemanasan menjadi faktor yang memengaruhi rendahnya aktivitas antioksidan.
Pengaruh Pengeluaran Bulanan Terhadap Persepsi Peran Apoteker Komunitas Indonesia dalam Mencegah Resistensi Antibiotika Olivke, Debora; Soegiantoro, Didiek Hardiyanto; Yuhara, Novena Adi
Jurnal Kesehatan Ilmiah Aufa Royhan Vol 10 No 2 (2025): Vol. 10 No. 2 Desember 2025
Publisher : Universitas Aufa Royhan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51933/health.v10i2.2427

Abstract

Community pharmacists have an important role in health services, especially in providing education on the use of drugs and preventing antibiotic abuse amid rising antimicrobial resistance. Public perception of the role of community pharmacists is still not optimal, influenced by limited knowledge and socio-economic factors, such as monthly expenses. This study aims to analyze the influence of monthly expenditure on the perception of the Indonesian public regarding the role of community pharmacists in preventing antibiotic resistance. The study used a cross-sectional design with a quantitative approach, involving 100 respondents through a questionnaire distributed online through googleform. Perceptions were analyzed based on six aspects: General Awareness, Effectiveness, Collaborative, Barriers, Trustworthiness, and antibiotic resistance. The results of the validity test showed the value of the KMO and Bartlett's Test with a value of 0.689, with a significance (p< 0.001) indicating that the data was worth analysis, while the reliability of the instrument was good with Cronbach's Alpha 0.670 which indicated a reliable instrument when >0.6. Chi-square analysis showed that monthly expenditure had no significant effect on public perception (p = 0.186). The Rank Spearman correlation test showed that all variables were significantly related (p < 0.001) with positive direction and correlation strength was strong enough to be strong (r = 0.443–0.776), and the strongest correlation was between Collaborative and Barriers (r = 0.776). These findings confirm the importance of the role of community pharmacists in antibiotic education and collaboration with health care workers, as well as encourage further research using longitudinal designs or adding other variables that influence antibiotic use behavior.
PENGARUH USIA TERHADAP PERSEPSI MASYARAKAT ATAS PERAN APOTEKER DALAM PELAYANAN SWAMEDIKASI Koa, Oktaviana; Soegiantoro, Didiek Hardiyanto; Yuhara, Novena Adi
Jurnal Kesehatan Ilmiah Aufa Royhan Vol 10 No 2 (2025): Vol. 10 No. 2 Desember 2025
Publisher : Universitas Aufa Royhan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51933/health.v10i2.2434

Abstract

Community pharmacists have an important role in public health services, especially in self-medication services, namely the use of drugs without a doctor's prescription to treat minor complaints, although public perception of the role of pharmacists can differ between regions; the purpose of this study was to see the extent of the influence of Indonesian public perception on the role of community pharmacists in self-medication service practices using quantitative methods with a cross-sectional design through the distribution of online questionnaires covering six variables: General Awareness (GA), Effectiveness (EFF), Collaboration (COLL), Barriers (BARR), Trustworthiness (TRUST), and Self-medication Services, where the validity test with KMO and Bartlett's Test and PCA factor analysis showed a KMO value > 0.771 which met the construct feasibility requirements, while Cronbach's Alpha reliability > 0.743 indicated very good internal consistency; Chi-Square analysis for the influence of age and Pearson correlation between variables yielded a significance value > 0.05, meaning there was no significant relationship between age and respondents' perceptions, indicating a consistent relationship between constructs, with the highest correlation between self-medication service and barriers (r = 0.780), indicating the higher the perceived barriers, the stronger the relationship with self-medication services. The government and pharmacists are intensifying education to reduce barriers, pharmacists are strengthening collaboration and trust through personalized consultations, developing mobile drug consultation applications, and further research in specific areas to explore other factors such as education.
Antibacterial Activity Test of Green Betel Leaf Extract Clay Mask (Piper Betle L) Against Acne-Causing Bacteria (Propionibacterium Acnes) Karinda, Yosi; Adi Yuhara, Novena; Ellsya Angeline Rawar
Jurnal EduHealth Vol. 16 No. 04 (2025): Jurnal EduHealt, Edition October-December , 2025
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Propionibacterium acnes is one of the bacteria that causes acne. Green betel leaf ( Piper betle L.) is a plant that has been used for generations. Green betel leaf extract contains flavonoids, tannins, saponins, alkaloids, and phenols that have antibacterial potential. Clay masks are solid mask preparations formulated with clay minerals as the base ingredient. This study aims to determine the characteristics of an anti-acne clay mask made from green betel leaf extract and its antibacterial activity against Propionibacterium acnes. Green betel leaves were extracted through maceration method using 96% ethanol solvent then made 4 clay mask preparations which were tested for organoleptic, pH, homogeneity, spreadability, adhesive power and drying time and antibacterial test was carried out using well method, inhibition zone data were tested using One-Way ANOVA and Duncan test to determine whether there were significant differences between each formula. The results of this study aimed to determine the physical quality and antibacterial activity of green betel leaf extract clay mask preparations against Propionibacterium acnes . The clay mask formula used consisted of F0 (without extract), F1, F2, and F3 with concentration variations of 2.5%, 5% and 7.5% extract. Evaluation of physical quality included organoleptic, homogeneity, pH, spreadability, adhesive power, and drying time tests. The results of the physical preparation test of the green betel leaf ethanol extract clay mask showed a soft, homogeneous shape, green color, betel leaf aroma, Ph around 5-6, spreadability of 5.23-6.73 cm, adhesiveness of 15.5-24.7 seconds and drying time of 12.7-15 minutes. The antibacterial activity test showed that F3 produced the largest inhibition zone of 3 2.9 mm. Statistical analysis using One-Way ANOVA showed that variations in extract concentration had a significant effect on antibacterial activity. Thus, the green betel leaf extract clay mask , especially the F3 formula, has good physical quality and the highest effectiveness as an anti-acne preparation.
Formulation and Determination of SPF Value of Sunscreen Spray with Cymbopogon Nardus L. Essential Oil Kristiana, Agita; Rawar, Ellsya; Yuhara, Novena Adi
Jurnal EduHealth Vol. 16 No. 04 (2025): Jurnal EduHealt, Edition October-December , 2025
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Ultraviolet light exposure creates free radicals in skin causing skin problems. To overcome this, sunscreens containing synthetic chemical substances can absorb ultraviolet rays and ward off free radicals that are formed, but the downside of sunscreen creams and lotions is that they are sticky and need to be adjusted to human skin type. Essential oil from Cymbopogon nardus L. containing citronellal, geraniol, and other flavonoid compounds which have sunscreen and antioxidant activity can be developed into a sunscreen preparation, namely spray sunscreen which is non-sticky and suitable for all skin types. The objective of this study was to obtain a sunscreen spray formula containing citronella essential oil that meets all physical preparation test requirements and has the highest SPF value. The research design is laboratory experimental study with citronella essential oil formulated in four variations of sunscreen spray formula (F0, F1, F2, F3) with concentrations of 0%, 5%, 7.5%, and 10%. The research methods are essential oil extraction by steam-water distillation, phytochemical screening, formulation, physical evaluation (organoleptic, pH, homogeneity, and viscosity testing), dan SPF activity test using spectrophotometer UV-Vis. All formulas exhibited acceptable physical characteristics with a constant pH of 7, homogeneous, and varying viscosity. The highest SPF values was F3 (12.13±0.00) with low protection. These results indicate that citronella essential oil can be incorporated into a sunscreen spray formulation that meets physical quality requirements and provides UV protection with the highest SPF value owned by F3.
Co-Authors Agustinus Jitro Nono Charis, Jesisca Christiani, Grace Joy Devia Danila Dewi Magistasari Ellsya Angeline Rawar Felik Felik Fenty Fenty, Fenty Happy Elda Murdiana, Happy Elda Ikakusumawati, Novita Dhewi Karinda, Yosi Koa, Oktaviana Kristiana, Agita Losi Yenni Florindha Magistasari, Dewi Manise, Chyntia Clarisa Mayi, Anggriana Rambu Gadi Novita Dhewi Ikakusumawati Olivke, Debora Rawar, Ellsya Sarah Puspita Atmaja Soegiantoro, Didiek Hardiyanto Supanji Supanji Supanji, Supanji Susi Ari Kristina Susi Ari Kristina Tabita Rahmavika Tatambihe, Naomi Azazya Teofilia Alvanes Kronikel Gea Tri Murti Andayani Tri Murti Andayani Wahyukurnia, Pilar Tesalonika Yosua Adi Kristariyanto