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All Journal Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) JCES (Journal of Character Education Society) JURNAL KESEHATAN PERINTIS Jurnal Farmasi Higea Jurnal Kesehatan Ilmiah Indonesia / Indonesian Health Scientific Journal Diseminasi : Jurnal Pengabdian kepada Masyarakat Jurnal Buana Farma Jurnal EduHealth Universitas Muhammadiyah Yogyakarta Undergraduate Conference Proceeding Farmasis: Jurnal Sains Farmasi Duta Pharma Journal Innovative: Journal Of Social Science Research Jurnal Pengabdian Kepada Masyarakat: Kesehatan (JPKMK) Jurnal Mahasiswa Ilmu Kesehatan JURNAL FARMASI DAN KESEHATAN INDONESIA Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Novena Adi Yuhara
Universitas Kristen Immanuel
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PENETAPAN KADAR FLAVONOID TOTAL DAN UJI AKTIVITAS ANTIOKSIDAN INFUSA BUNGA KERTAS (Bougenvillea glabra) DENGAN SPEKTROFOTOMETER UV-Vis Rawar, Ellsya; Charis, Jesisca; Adi Yuhara, Novena
Duta Pharma Journal Vol. 5 No. 2 (2025): Duta Pharma Journal
Publisher : Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/whnsee23

Abstract

Latar Belakang : Pola makan yang tidak sehat serta paparan stres dapat meningkatkan risiko penyakit degeneratif. Salah satu mekanismenya adalah stres oksidatif yang terjadi ketika jumlah radikal bebas dalam tubuh melebihi kapasitas antioksidan endogen. Flavonoid merupakan metabolit sekunder yang berperan sebagai antioksidan alami dan banyak ditemukan pada tumbuhan, termasuk bunga kertas (Bougainvillea glabra). Tujuan: Penelitian ini bertujuan untuk menentukan kadar flavonoid total serta nilai IC50 sebagai indikator aktivitas antioksidan infusa bunga kertas. Metode: Penelitian diawali dengan penyiapan simplisia melalui proses pengeringan dan penghalusan bunga, kemudian pembuatan infusa pada suhu 90 °C selama 15 menit. Identifikasi flavonoid dilakukan secara kualitatif menggunakan reagen spesifik. Penetapan kadar flavonoid total menggunakan metode kolorimetri dengan reagen AlCl? dan CH3COOK pada infusa 10% (10 g/100 mL). Aktivitas antioksidan diuji menggunakan metode DPPH untuk memperoleh nilai IC50. Hasil: Uji kualitatif menunjukkan adanya flavonoid yang ditandai dengan perubahan warna larutan menjadi jingga. Infusa bunga kertas 10% memiliki kadar flavonoid total sebesar 12,10±0,55 mgEK/10 g. Uji aktivitas antioksidan menunjukkan bahwa nilai IC?? infusa sebesar 703,34±12,37 µg/mL, yang mengindikasikan aktivitas antioksidan sangat lemah. Rendahnya aktivitas ini diduga terkait dengan kelarutan flavonoid yang kurang optimal dalam air serta kemungkinan degradasi senyawa pada pemanasan 90 °C. Kesimpulan: Infusa bunga kertas mengandung flavonoid, namun memiliki aktivitas antioksidan yang sangat lemah. Rendahnya kadar flavonoid terlarut dan potensi kerusakan senyawa akibat pemanasan menjadi faktor yang memengaruhi rendahnya aktivitas antioksidan.
Pengaruh Pengeluaran Bulanan Terhadap Persepsi Peran Apoteker Komunitas Indonesia dalam Mencegah Resistensi Antibiotika Olivke, Debora; Soegiantoro, Didiek Hardiyanto; Yuhara, Novena Adi
Jurnal Kesehatan Ilmiah Aufa Royhan Vol 10 No 2 (2025): Vol. 10 No. 2 Desember 2025
Publisher : Universitas Aufa Royhan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51933/health.v10i2.2427

Abstract

Community pharmacists have an important role in health services, especially in providing education on the use of drugs and preventing antibiotic abuse amid rising antimicrobial resistance. Public perception of the role of community pharmacists is still not optimal, influenced by limited knowledge and socio-economic factors, such as monthly expenses. This study aims to analyze the influence of monthly expenditure on the perception of the Indonesian public regarding the role of community pharmacists in preventing antibiotic resistance. The study used a cross-sectional design with a quantitative approach, involving 100 respondents through a questionnaire distributed online through googleform. Perceptions were analyzed based on six aspects: General Awareness, Effectiveness, Collaborative, Barriers, Trustworthiness, and antibiotic resistance. The results of the validity test showed the value of the KMO and Bartlett's Test with a value of 0.689, with a significance (p< 0.001) indicating that the data was worth analysis, while the reliability of the instrument was good with Cronbach's Alpha 0.670 which indicated a reliable instrument when >0.6. Chi-square analysis showed that monthly expenditure had no significant effect on public perception (p = 0.186). The Rank Spearman correlation test showed that all variables were significantly related (p < 0.001) with positive direction and correlation strength was strong enough to be strong (r = 0.443–0.776), and the strongest correlation was between Collaborative and Barriers (r = 0.776). These findings confirm the importance of the role of community pharmacists in antibiotic education and collaboration with health care workers, as well as encourage further research using longitudinal designs or adding other variables that influence antibiotic use behavior.
PENGARUH USIA TERHADAP PERSEPSI MASYARAKAT ATAS PERAN APOTEKER DALAM PELAYANAN SWAMEDIKASI Koa, Oktaviana; Soegiantoro, Didiek Hardiyanto; Yuhara, Novena Adi
Jurnal Kesehatan Ilmiah Aufa Royhan Vol 10 No 2 (2025): Vol. 10 No. 2 Desember 2025
Publisher : Universitas Aufa Royhan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51933/health.v10i2.2434

Abstract

Community pharmacists have an important role in public health services, especially in self-medication services, namely the use of drugs without a doctor's prescription to treat minor complaints, although public perception of the role of pharmacists can differ between regions; the purpose of this study was to see the extent of the influence of Indonesian public perception on the role of community pharmacists in self-medication service practices using quantitative methods with a cross-sectional design through the distribution of online questionnaires covering six variables: General Awareness (GA), Effectiveness (EFF), Collaboration (COLL), Barriers (BARR), Trustworthiness (TRUST), and Self-medication Services, where the validity test with KMO and Bartlett's Test and PCA factor analysis showed a KMO value > 0.771 which met the construct feasibility requirements, while Cronbach's Alpha reliability > 0.743 indicated very good internal consistency; Chi-Square analysis for the influence of age and Pearson correlation between variables yielded a significance value > 0.05, meaning there was no significant relationship between age and respondents' perceptions, indicating a consistent relationship between constructs, with the highest correlation between self-medication service and barriers (r = 0.780), indicating the higher the perceived barriers, the stronger the relationship with self-medication services. The government and pharmacists are intensifying education to reduce barriers, pharmacists are strengthening collaboration and trust through personalized consultations, developing mobile drug consultation applications, and further research in specific areas to explore other factors such as education.
ATR-FTIR Spectral Profiling and PCA of Red Ginger (Zingiber officinale var. rubrum) from Java, Indonesia Maria Serliati Ngongo; Novena Adi Yuhara; Ellsya Rawar
Duta Pharma Journal Vol. 6 No. 1 (2026): Duta Pharma Journal
Publisher : Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/2jsq5e89

Abstract

Background: Red ginger (Zingiber officinale var. rubrum) is a herbal plant widely used in traditional medicine due to its various bioactive compounds, which are influenced by geographical and agroclimatic conditions. Objectives: This study aimed to distinguish the Fourier Transform Infrared (FTIR) spectral profiles of red ginger in Java, Indonesia using Principal Component Analysis (PCA). Methodology: Red ginger samples from six regions, namely Jatinangor, Ciamis, Trenggalek, Bogor, Sumedang, and Wonogiri, were dried, ground, and analysed using ATR-FTIR in the wavenumber range of 4000-400 cm?¹. The transmittance data were processed using PCA in XLSTAT. Dry weight loss was determined using an oven at 105°C to evaluate the water content of the medicinal plants. Results: The results of dry weight loss showed an average value ranging from 9.24% to 11.96%. Samples from Ciamis (11.76%), Sumedang (11.96%), Trenggalek (10.84%), and Bogor (10.15%) exceeded the required standard limit (<10%), while the other samples met the standard requirements. FTIR spectral analysis revealed the presence of O–H, C–H, C=O, C=C, and C–O functional groups associated with gingerol and shogaol compounds. PCA analysis showed that two principal components, PC1 and PC2, explained 96.798% of the total variation in the data. The score plot showed sample clustering by geographical origin, with Jatinangor, Trenggalek, and Bogor exhibiting relatively similar spectral characteristics, whereas Sumedang, Ciamis, and Wonogiri showed distinct profiles. Contribution analysis showed that Ciamis and Wonogiri contributed mostly to the formation of PC1, while Ciamis and Sumedang contributed significantly to PC2. PCA is used to distinguish the spectral profiles of red ginger based on the regional origin of the tested samples as an initial overview for explanation without a validated classification model. Conclusions: This study demonstrated that the combination of ATR-FTIR and PCA is an effective, rapid method for differentiating the spectral profiles of red gingers by geographical origin.
Co-Authors Agustinus Jitro Nono Charis, Jesisca Christiani, Grace Joy Devia Danila Dewi Magistasari Ellsya Angeline Rawar Ellsya Rawar Felik Felik Fenty Fenty, Fenty Happy Elda Murdiana, Happy Elda Ikakusumawati, Novita Dhewi Koa, Oktaviana Losi Yenni Florindha Magistasari, Dewi Manise, Chyntia Clarisa Maria Serliati Ngongo Mayi, Anggriana Rambu Gadi Novita Dhewi Ikakusumawati Olivke, Debora Rawar, Ellsya Sarah Puspita Atmaja Soegiantoro, Didiek Hardiyanto Supanji Supanji Supanji, Supanji Susi Ari Kristina Susi Ari Kristina Tabita Rahmavika Tatambihe, Naomi Azazya Teofilia Alvanes Kronikel Gea Tri Murti Andayani Tri Murti Andayani Wahyukurnia, Pilar Tesalonika Yosua Adi Kristariyanto