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Journal : medisains

Potential of turmeric cream (curcuma caesia roxb.) extract in incision wounds Udayani, Ni Nyoman Wahyu; Adrianta, I Ketut Agus; Wiguna, I Putu Bagus Artha; Yowani, Anak Agung Sagung Iswarani
MEDISAINS Early Release
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v0i0.23731

Abstract

Background: Incisional wounds are the most common wounds in the community. Improper handling of incision wounds can worsen wounds and cause infection. The content of secondary metabolites in black turmeric rhizomes can act as anti-inflammatory and antimicrobial in the healing process of incision wounds. However, its effectiveness in healing incision wounds has not been widely studied, so further research is needed.Purpose: This study was conducted to determine the potential of black turmeric cream as an herbal medicine to heal incision wounds.Methods: This study was an invivo experimental research study with a randomized post-test control group design. The samples used were 20 male rats that were made to have a 2 cm incision wound on the back area, consisting of a negative control, a positive control, and three black turmeric extract groups (5%, 10%, and 15%). The data obtained were analyzed by an ANOVA (Analysis of Variance) parametric statistical test.Result: The results showed that the highest decrease in incision wound length was found in the black turmeric rhizome cream Formula III group and the lowest in the negative control group. On day 14, the incision wound area of the Formula III black turmeric rhizome cream group had closed or healed (0.00 cm), while the negative control group had the slowest incision wound closure (0.39 cm).Conclusion: Black turmeric rhizome cream can heal and prevent infection of the incision wound. This shows the potential of black turmeric rhizome as an anti-inflammatory and antimicrobial.
Potential of turmeric cream (curcuma caesia roxb.) extract in incision wounds Udayani, Ni Nyoman Wahyu; Adrianta, I Ketut Agus; Wiguna, I Putu Bagus Artha; Yowani, Anak Agung Sagung Iswarani
MEDISAINS: Jurnal Ilmiah Ilmu-Ilmu Kesehatan Early Release
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v0i0.23731

Abstract

Background: Incisional wounds are the most common wounds in the community. Improper handling of incision wounds can worsen wounds and cause infection. The content of secondary metabolites in black turmeric rhizomes can act as anti-inflammatory and antimicrobial in the healing process of incision wounds. However, its effectiveness in healing incision wounds has not been widely studied, so further research is needed.Purpose: This study was conducted to determine the potential of black turmeric cream as an herbal medicine to heal incision wounds.Methods: This study was an invivo experimental research study with a randomized post-test control group design. The samples used were 20 male rats that were made to have a 2 cm incision wound on the back area, consisting of a negative control, a positive control, and three black turmeric extract groups (5%, 10%, and 15%). The data obtained were analyzed by an ANOVA (Analysis of Variance) parametric statistical test.Result: The results showed that the highest decrease in incision wound length was found in the black turmeric rhizome cream Formula III group and the lowest in the negative control group. On day 14, the incision wound area of the Formula III black turmeric rhizome cream group had closed or healed (0.00 cm), while the negative control group had the slowest incision wound closure (0.39 cm).Conclusion: Black turmeric rhizome cream can heal and prevent infection of the incision wound. This shows the potential of black turmeric rhizome as an anti-inflammatory and antimicrobial.
Co-Authors Agung Ari Chandra Wibawa Agung Ari Chandra Wibawa Agung Ari Chandra Wibawa Agung Ari Chandra Wibawa Agung Nova Mahendra Agung Wiwiek Indrayani Anak Agung Cahaya Dayita Nariswari Bagus Komang Satriyasa Berata, Putu Febryana Suryaputri Debby Juliadi Desak Ketut Ernawati Desak Made Wihandani Dewa Ayu Ika Pramitha Dwi Arymbhi Sanjaya Fitria Megawati Fridayana, Ni Luh Gede Erica Gamaliel Agripa Gunawan, I Putu Windra Herleeyana Meriyani I Gede Made Suradnyana I Gusti Agung Ayu Kusuma Wardhani I Made Jawi I Nyoman Gede Tri Sutrisna I Putu Werda Bisama I Wayan Suardi Adi Gunawan I Wayan Surya Rahadi Ida Bagus Ideyogiswara IGAA Kusuma Wardani Kadek Ayu Puspa Pratiwi Kamalia, Made Gek Adisti Lusy Noviani Made Dwik Lestari Mahaputra, I Putu Yudistira Malelak, Julia Eva Mardiyanti Putri, Ni Putu Kania Marliani, Ni Luh Setia Mas Tiari, Ida Ayu Dwi Putri Megawati, Fitria Mendra, Ni Nyoman Yudianti Meriana Barreto Amaral Nggaba, Ellenoire Rambu Kabeba Hammu Ni Kadek Ayu Mas Ratnadewi Ni Komang Puja Pertiwi Ni Luh Kade Arman Anita Dewi Ni Luh Putu Anggie Pramesthi Putri Ni Luh Putu Tris Yoga Cahyani Ni Made Dharma Shantini Suena Ni Made Maharianingsih Ni Made Sukma Sanjiwani Ni Nyoman Sri Budayanti Ni Nyoman Wahyu Udayani Ni Putu Aryati Suryaningsih Ni Putu Ayu Widya Anggreni Ni Putu Leona Yorita Dewi Ni Putu Putri Cahya Anggreni Ni Putu Refina Dharma Yanti Ni Putu Siska Sugiantari Ni Putu Udayana Antari Nyoman Budiartha Siada Puguh Santoso Puguh Santoso puguh santoso, puguh Putra, I Made Agus Sunadi Putu Windra Gunawan Rahadi, I Wayan Surya Ratnadewi, Ni Kadek Ayu Mas RR. Asih Juanita Samidya, Ni Wayan Rias Sari, Ni Made Elma Agustini Sari, Ni Wayan Suryani Puspita Shiendy Ayu Puspita Suradnyana, I Gede Made Susianti, Luh Sutema, Ida Ayu Manik Partha Veryanti, Putu Rika Wardani, I Gusti Agung Ayu Kusuma Wartana Putra, I Gusti Ngurah Agung Windra Widowati, I Gusti Ayu Rai - Wiguna, I Putu Bagus Artha Yanti, Ni Komang Semara Yeni Cendana Yowani, Anak Agung Sagung Iswarani