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All Journal Mutiara Medika: Jurnal Kedokteran dan Kesehatan BIOMA : Jurnal Biologi Makassar Medical Laboratory Technology Journal Jurnal Surya Medika Journal of Experimental and Clinical Pharmacy (JECP) Pengabdian Kampus: Jurnal Informasi Kegiatan Pengabdian Pada Masyarakat Pharmaceutical Sciences and Research (PSR) Jurnal Ilmu Multidisplin Barigas: Jurnal Riset Mahasiswa Journal of Mathematics, Computation and Statistics (JMATHCOS)
Widayati, Ratna
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Efektivitas Penyembuhan Luka Sediaan Patch Kombinasi Beberapa Spesies Sirih Secara in Vivo Ranti, Dalia; Trinovita, Elsa; Praja, Rian Ka; Frethernety, Agnes; Widayati, Ratna
Journal of Experimental and Clinical Pharmacy (JECP) Vol 4, No 2 (2024): August 2024
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v4i2.960

Abstract

Luka merupakan permasalahan kesehatan dengan tingkat kejadian yang sering terjadi di Indonesia. Pemberian terapi berbahan herbal dapat menjadi salah satu alternatif dalam penyembuhan luka. Sirih merah (Piper crocatum) dan sirih hijau (Piper betle L.) mempunyai berbagai senyawa metabolit sekunder yang berperan dalam penyembuhan luka sayatan pada kulit. Penelitian ini bertujuan untuk mengetahui efektivitas sediaan patch kombinasi ekstrak daun sirih merah dan daun sirih hijau terhadap penyembuhan luka sayat. Hewan coba dibagi menjadi 5 kelompok perlakuan yaitu kontrol positif (plaster povidone iodine), kontrol negatif patch tanpa ekstrak, dan kelompok dengan ekstrak pada beberapa konsentrasi (7,5%, 15% dan 30%). Beberapa parameter yang dilakukan dengan pengukuran panjang luka, pengamatan waktu penyembuhan luka dan infeksi lokal berdasarkan kriteria Nagaoka. Sediaan patch kombinasi ekstrak daun sirih merah dan daun sirih hijau secara statistik tidak menunjukkan perbedaan bermakna terhadap efektivitas dalam penyembuhan luka yang dinilai berdasarkan kriteria Nagaoka dengan beberapa parameter penilaian luka. Namun, pengamatan secara makroskopis pada kelompok K2 (konsentrasi 15%) menunjukkan terjadinya penyembuhan luka yang lebih baik dibandingkan dengan kelompok plaster povidone iodine. Wounds are a health problem that is a frequent occurrence in Indonesia. Providing herbal therapy can be an alternative for healing wounds. Red betel (Piper crocatum) and green betel (Piper betle L.) have various secondary metabolite compounds that play a role in healing wounds of skin incisions. This study aims to determine the effectiveness of a combination patch preparation of red betel leaf extract and green betel leaf in healing cuts on the skin. The experimental animals were divided into five treatment groups: positive control (povidone-iodine plaster), negative control patch without extract, and groups with extract at several concentrations (7.5%, 15%, and 30%). Several parameters were measured by measuring wound length and observing wound healing time and local infection based on the Nagaoka criteria. The combination patch preparation of red betel leaf extract and green betel leaf extract did not statistically show a significant difference in effectiveness in wound healing as assessed based on the Nagaoka criteria with several wound assessment parameters. However, macroscopic observation in the K2 group (concentration 15%) showed better wound healing compared to the povidone-iodine plaster group.
Hubungan kebersihan diri dengan kecacingan pada siswa kelas 3 – 5 SDN 1 Pahandut Seberang Kota Palangka Raya Tahun 2022 Kristiani, Friska Merilia Dwi; Maulia, Desi Rahma; Toemon, Agnes Immanuela; Widayati, Ratna; Augustina, Indria; Lestarisa, Trilianty; Jabal, Arif Rahman; Adryannoor, Muhammad Rafli
Barigas: Jurnal Riset Mahasiswa Vol. 1 No. 1 (2023): Barigas: Jurnal Riset Mahasiswa
Publisher : Fakultas Kedokteran Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/barigas.v1i1.7937

Abstract

Soil Transmitted Helminths (STH) are a group of intestinal nematode parasites that cause infection in humans, particularly children with poor hygiene. Ascaris lumbricoides, one of the most common intestinal nematodes, can be spread through infective eggs consumed with contaminated food or drink, as well as through dirty hands due to contaminated soil containing infective eggs. This study aims to determine the relationship between personal hygiene and worms in grade 3-5 children at SDN 1 Pahandut Seberang, Palangka Raya City.This research was conducted using the analytical observational research method with a cross sectional approach. The sample used was 41 students from grades 3-5 of SDN 1 Pahandut Seberang. This study revealed that 23 students (56.1%) had good personal cleanliness, while 18 students (43.9%) had poor personal hygiene. Two pupils (4.9%) tested positive for helminthiasis out of a total of 39 students (95.1%). According to the Fisher's Exact test, the obtained findings were p = 0.187. There is no significant correlation between personal hygiene and worm infestation.
HUBUNGAN TINGKAT STRES DENGAN KUALITAS TIDUR PADA MAHASISWA PREKLINIK FAKULTAS KEDOKTERAN UNIVERSITAS PALANGKA RAYA Sibarani, Juliet Valeria; Widayati, Ratna; Mutiasari, Dian
Barigas: Jurnal Riset Mahasiswa Vol. 1 No. 1 (2023): Barigas: Jurnal Riset Mahasiswa
Publisher : Fakultas Kedokteran Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/barigas.v1i1.8033

Abstract

Various demands based on competence result in a lot of stress for medical students which is relatively greater when compared to students in other faculties, resulting in frequent stress for the medical students. College students have the potential to experience stress which results in disrupted sleep quality. This study used an analytic observational method with a cross-sectional design. The sample used amounted to 192 respondents. The data were then analyzed using Kendall's Tau with a significance value (<0.05). Sampling was carried out using Simple Random Sampling technique, by looking at the results of data collection using DASS-42 questionnaire to see stress levels and PSQI questionnaire to see sleep quality. The results of this study indicate that of the 192 samples found normal stress levels were 81 (42.2%), mild stress levels 49 (25.5%), moderate stress 35 (18.2%), severe stress 24 (12, 5%), and very severe 3 (1.6%). Meanwhile, the results showed that 176 (91.7%) had poor sleep quality and 16 (8.3%) had good sleep quality. Based on the results of the analysis, it shows that there is a significant relationship between stress levels and sleep quality in preclinic students at the Faculty of Medicine, University of Palangka Raya with a closeness value is in moderate category.
The Effect of Methanol Fractıonated of Luvunga sarmentosa on In Vıtro Sperm Membrane Integrıty Permatasari, Silvani; Nuha, Alya Firyal; Ratnasari, Arini; Widayati, Ratna; Ka Praja, Rian
Medical Laboratory Technology Journal Vol. 10 No. 1 (2024): June
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/mltj.v10i1.571

Abstract

Infertility cases in the world are increasing in 2020, with 186 million individuals affected worldwide. The most common cause of male infertility is due to decreased sperm quality. Sperm membrane integrity is known to play an essential role in the fertilization ability of spermatozoa. The methanol fraction of Luvunga sarmentosa root extract has the highest antioxidant activity compared to other fractions and can improve sperm motility in vitro. This study aims to determine the effect of the methanol fraction of Luvunga sarmentosa root extract on human sperm membrane integrity and the effective concentration of Luvunga sarmentosa methanol extract fraction to improve sperm membrane integrity in vitro. The samples used were washed human spermatozoa in vitro, then added BWW medium, and incubated at 37℃ for 1 hour with methanol fraction of Luvunga sarmentosa root extract at concentrations of 100, 500, 1000, and 5000ng/ml as well as the control group (BWW only). Furthermore, 100uL of each sample was added to 1mL of Hypo-osmotic swelling (HOS) solution, then incubated at 37oC for 30 minutes to see the integrity of the spermatozoa membrane from the tail swelling. The results showed that sperm membrane integrity significantly increased at 100, 500, 1000, and 5000ng/mL concentrations compared to the control group. The methanol fraction of Luvunga sarmentosa root extract was most effective at a concentration of 100ng/mL. Methanol fraction of Luvunga sarmentosa root extract can improve human sperm membrane integrity.
The Correlation between Protein, Iron, and Vitamin C Intake with Hemoglobin Levels in Pregnant Women Sitorus, Elisabeth Prihana Rotua; Handayani, Septi; Balyas, Abi Bakring; Widayati, Ratna; Fatmaria, Fatmaria; Permatasari, Silvani
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 24, No 1 (2024): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v24i1.17311

Abstract

Hemoglobin is an important component of the human body. It aims to transport oxygen and carbon dioxide. Anemia during pregnancy often occurs in the second trimester. Pregnant women tend to be vulnerable to malnutrition since their nutritional needs will increase to satisfy the needs of both the mother and the fetus. Protein intake plays a crucial role in the transportation of iron in the body. Meanwhile, vitamin C serves as a promoter of iron absorption. This research aims to determine and analyze the correlation between protein, iron, and vitamin C intake and hemoglobin levels in pregnant women at Kayon Public Health Center, Jekan Raya District. This research used an analytic observational method with a cross-sectional approach and a purposive sampling technique. Bivariate analysis was also applied by using the Spearman test. The latter results obtain a p-value of 0.748 between protein intake and hemoglobin level; a p-value of 0.222 between vitamin C intake and hemoglobin level; and a p-value of 0.050 between iron intake and hemoglobin level. There was a correlation between iron intake and hemoglobin level, yet there was no correlation between protein and vitamin C intake with hemoglobin level.
Kendali Optimal pada Penyebaran Penyakit Covid-19 berdasarkan model SIVRS Widayati, Ratna; Ahmad, Mizan; Sofiyati, Noor
Journal of Mathematics, Computations and Statistics Vol. 6 No. 2 (2023): Volume 06 Nomor 02 (Oktober 2023)
Publisher : Jurusan Matematika FMIPA UNM

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This study discusses about optimal control for spread of Covid-19 disease with the assumptionthat there is a subpopulation of individuals infected with the new variant of Covid-19. Transmission canoccur between individuals in susceptible subpopulations and individuals in subpopulations infected withCovid-19. SIVRS model is used by assumes that there is control variable in the form of the vaccinationstrategy given to susceptible individuals. This study aims to minimize the number of individuals in thesubpopulation infected and infected with the new variant. An analysis of the optimal control solution wascarried out using the Hamiltonian function and then solving it using the Sweep Forward and Back methodin Matlab. The results show that the vaccination strategy implemented can minimize the number ofindividuals in the subpopulation infected and infected with the new variant.
Korelasi kadar bikarbonat dengan QSOFA score pada pasien sepsis di RSUD dr. Doris Sylvanus Adelia, Sirli; Widayati, Ratna; Surbakti, Ranintha br; Patricia, Tisha; Martani, Natalia Sri
Barigas: Jurnal Riset Mahasiswa Vol. 2 No. 3 (2024): Barigas: Jurnal Riset Mahasiswa
Publisher : Fakultas Kedokteran Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/barigas.v2i3.11665

Abstract

Sepsis is a life-threatening medical emergency due to organ dysfunction described by the body's systemic immunological response to an infectious reaction. Sepsis patients experience sequential system failure, leading to multiple organ failure Sepsis sufferers experience organ failure will experience metabolic acidosis. An indicator of metabolic acidosis is a decrease in bicarbonate. qSOFA is required to determine the risk of organ failure in sepsis patients. To analyze the correlation of bicarbonate levels with qSOFA score in sepsis patients. The relationship between bicarbonate levels and qSOFA was tested using the Pearson correlation. There was no statistically significant with p value = 0.099 and r value = -0.307. Conclusion: There is no significant relationship between bicarbonate levels and qSOFA scores in sepsis patients at RSUD dr. Doris Sylvanus, there is a low correlation intensity with a negative correlation direction, indicating higher bicarbonate levels, lower qSOFA scores.
Upaya Peningkatan Pengetahuan tentang Infeksi Menular Seksual pada Remaja di SMAN 4 Palangka Raya Permatasari, Silvani; Widayati, Ratna; Handayani, Septi
Jurnal Pengabdian Kampus Vol 11 No 2 (2024): Jurnal Pengabdian Kampus
Publisher : LPPM Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52850/jpmupr.v11i2.16634

Abstract

Sexually Transmitted Infection (STI) is an infection triggered by bacteria, viruses, protozoa, parasites and fungi which is transmitted mainly through sexual contact, including anal and oral. Apart from that, STIs can also be transmitted through direct contact with contaminated objects, for example towels, sex toys, syringes, thermometers, and also through pregnant women to their fetuses or during the birth stage. One age group that is vulnerable to STIs is teenagers. Teenagers are more often encouraged to explore sexual experiences, which can increase the risk of experiencing STIs. One of the problems of teenagers at SMAN 4 Palangka Raya based on the results of interviews with students related to STI cases is the low level of knowledge about STIs. This service activity aims to increase teenagers' knowledge about STIs and spread this knowledge to the surrounding environment. The method used is a lecture containing material about the definition and meaning of STIs, the causes of STIs, symptoms caused by STI-causing agents in both men and women, how STIs are transmitted and how to prevent them. Service activities begin with socialization, implementation and evaluation of results. The implementation of Community Service activities in the form of efforts to increase knowledge about sexually transmitted infections in adolescents at SMAN 4 Palangka Raya was successful, participants enthusiastically listened to the material presented. There was a significant increase in knowledge after counseling compared to the pretest. Counseling can increase students' knowledge about the types of STIs and their complications.
Gastroprotective Potential of Medicinal Plant From Central Kalimantan: Sungkai Leaves (Peronema canescens Jack)-Ultrasonic Assisted Extraction in Rats Induced with Absolute Ethanol Savitri, Dilasari; Trinovita, Elsa; Widayati, Ratna; Handayani, Septi; Nugrahini, Sintha
Pharmaceutical Sciences and Research Vol. 12, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Peptic ulcer disease is a gastrointestinal disorder associated with significant morbidity and mortality. Enhancing the quality of life of patients with peptic ulcers often involves integrating conventional treatments with complementary alternative therapies. One such alternative therapy is herbal remedies, which local communities have long recognized. Sungkai leaves (Peronema canescens Jack) contain various bioactive components, including flavonoids, alkaloids, saponins, tannins, steroids, and phenolic compounds. This study aimed to assess the gastroprotective properties of sungkai leaf extract (Peronema canescens Jack) by analyzing the average size of gastric lesions in male Wistar rats exposed to absolute ethanol. The research used a true experimental design with a posttest-only control group approach involving six treatment groups, each consisting of four rats. Gastroprotective activity was macroscopically evaluated by measuring the average size of the gastric lesions. Statistical analyses were conducted using the Kruskal-Wallis and Mann-Whitney tests for post hoc comparisons. Results showed that the normal group had an average lesion size of 0 mm, the negative control group had 115.37±50.53 mm, and the positive control group had 7.40±2.57 mm. For the groups treated with sungkai leaf extract, the 100 mg/kgBW dose resulted in 6.86±3.83 mm lesions, the 200 mg/kgBW dose in 9.65±10.27 mm, and the 400 mg/kgBW dose in 29.50±19.68 mm. Statistical analysis using SPSS 26 revealed a significant difference between the groups,with a Kruskal-Wallis test result of p=0.002. These findings show that sungkai leaf extract exhibits gastroprotective activity compared with omeprazole, as seen by the smaller average size of gastric lesions in male Wistar rats treated with absolute ethanol.
DISTRIBUSI GEOGRAFIS Anopheles spp DI PALANGKA RAYA Augustina, Indria; Ratnasari, Arini; Karmila, Mila; Widayati, Ratna; Tarigan, Grandiano Escool; Sitohang, Ryan Ferdinand; Jabal, Arif
BIOMA : JURNAL BIOLOGI MAKASSAR Vol. 9 No. 2 (2024): Bioma : Juli - Desember 2024
Publisher : Department of Biology, Faculty of Mathematics and Natural Sciences, Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Potensi vektor malaria di Palangka Raya perlu diperhatikan mengenai habitat alami Anopheles sp. Malaria masih menjadi masalah kesehatan yang serius di Indonesia. Kasus malaria pernah terlaporkan di Kota Palangka Raya tepatnya di Kecamatan Bukit Batu. Tujuan penelitian ini untuk menganalisis distribusi  geografis nyamuk Anopheles spp. di Kota Palangka Raya. Total Anopheles sp. yang ditemukan di Palangka Raya sebesar 141 dari  dua spesies nyamuk An. barbirotris, dan An. Vagus. Spesies Anopheles sp yang ditemukan di Kota Palangka Raya yaitu An. vagus dan An. barbirostris. yang hanya tersebar di Kelurahan Tangkiling dan Tumbang Rungan. Metode animal bait trap paling efektif menangkap nyamuk An. vagus dan An. barbirostris dibandingkan metode lain. Sebaran Anopheles di Kota Palangka Raya hanya cocok di dua lokasi tersebut. Kata kunci :  Distribusi, geografis, Anopheles
Co-Authors Adelia, Sirli Adryannoor, Muhammad Rafli Alexandra, Francisca Diana Arif Rahman Jabal Arini Ratnasari Augustina, Indria Balyas, Abi Bakring Berliani, Victoria Dian Mutiasari, Dian Elsa Trinovita Fatmaria, Fatmaria Frethernety, Agnes Handayani, Septi Jabal, Arif Kristiani, Friska Merilia Dwi Lestarisa, Trilianty Maulia, Desi Rahma Mila Karmila Mizan Ahmad Natalia Sri Martani Nugrahini, Sintha Nuha, Alya Firyal Patricia, Tisha Permatasari, Silvani Ranintha br Surbakti Ranti, Dalia Rian Ka Praja Savitri, Dilasari Sibarani, Juliet Valeria Sitohang, Ryan Ferdinand Sitorus, Elisabeth Prihana Rotua Sofiyati, noor Tarigan, Grandiano Escool Toemon, Agnes Immanuela Zefanya, Thania