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All Journal HAYATI Journal of Biosciences CHEMPUBLISH JOURNAL Jurnal Farmasi Sains dan Komunitas Jurnal Penelitian Pendidikan IPA (JPPIPA) JCES (Journal of Character Education Society) Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Walisongo Journal of Chemistry Jurnal Kreativitas PKM Jambura Journal of Chemistry PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat JKPK (Jurnal Kimia dan Pendidikan Kimia) JURNAL REKAYASA KIMIA & LINGKUNGAN Jurnal Bioteknologi & Biosains Indonesia (JBBI) Jurnal Bioteknologi & Biosains Indonesia
Susanto, Nindita Clourisa Amaris
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Isolasi Senyawa Metabolit Sekunder dari Ekstrak Etil Asetat Daun Sungkai (Peronema canescens jack.) dan Uji Aktivitas Imunomodulator Safitri, Wulan; Latief, Madyawati; Susanto, Nindita Clourisa Amaris
Jambura Journal of Chemistry Vol 6, No 2 (2024): August
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/jambchem.v6i2.15506

Abstract

Sungkai (Peronema canescens Jack.) is a plant native to Indonesia that is traditionally used for dehumidifiers, treating malaria and increasing endurance. This study aims to isolate the compounds in the ethyl acetate extract of sungkai leaves and test the immunomodulatory activity of these compounds. Sungkai leaves were carried out stratified maceration using n-hexane, ethyl acetate and methanol solvents, then phytochemical screening of ethyl acetate extract of sungkai leaves, followed by an isolation process using the KVC method and isolates were obtained on F3. Phytochemical screening of F3 isolates contains steroid compounds. Immunomodulatory activity tests showed that in EEADS 50 mg/Kgbb, 150 mg/Kgbb, 450 mg/Kgbb, K+ and isolates there was an increase in the number of leukocytes and % macrophage activity compared to K-. The EEADS treatment of 50 mg/Kgbb, 150 mg/Kgbb and isolates of 0.7 mg/Kgbb did not differ markedly from K- but differed markedly from the EEADS treatment of 450 mg/Kgbb and K+. At a dose of 450 mg/Kgbb there was an increase in leukocytes and the highest % macrophage activity which was almost close to K+ (Imboost 0.7 mg/Kgbb). The UV-Vis spectrum of the F3 isolate shows a maximum absorption peak at 267 nm indicating the presence of a nonconjugation double bond. The FTIR spectrum shows isolates have groups O-H (3381.13cm-1), aliphatic C-H (2939.10cm-1), C=C (1631.44cm-1), C-H (1449.42-1362.82cm-1), and C-O (1022.32cm-1). Based on the literature comparison, the pattern of the UV-Vis spectrum and FTIR of F3 isolates has similarities with the UV-Vis and FTIR spectrum of steroid group compounds, namely β-Sitosterol.
Ekstrak Getah Merkubung (Macaranga gigantea) Sebagai Inhibitor Korosi Yang Ramah Lingkungan Pada Baja Lunak Dalam Media Air Gambut Prasetio, Muhamad Reza; Pradina, Armitha Dea; Gusti, Diah Riski; Susanto, Nindita Clourisa Amaris
Jambura Journal of Chemistry Vol 7, No 1 (2025): February
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/jambchem.v7i1.15714

Abstract

Pemanfaatan baja lunak dalam industri sebagai alat kontruksi dan transportasi karena baja memiliki banyak manfaat antara lain kokoh, mudah digunakan dan sederhana. Namun, baja rentan terkena korosi karena berinteraksi dengan kondisi lingkungan asam, alkali , dan lingkungan agresif lainnya. Ekstrak getah merkubung (Macaranga gigantea) dipilih sebagai inhibitor korosi karena mengandung senyawa metabolit sekunder, salah satunya yaitu tanin. Tujuan dari penelitian ini untuk manganalisis pengaruh konsentrasi ekstrak terhadap laju korosi, efisiensi dalam media air gambut. Metode pengujian yaitu metode kehilangan berat, dimana laju korosi tertinggi pada suhu 333 K dengan konsentrasi 0,5 g/L adalah 0,555 g/cm^2.jam. Sedangkan nilai efisiensi sebesar 67,196 % pada suhu 333 K dengan konsentrasi 2,5 g/L. Analisis yang digunakan pada penelitian ini yaitu Analisis Scanning Electron Microscopy/ Energy Dispersive X-Ray (SEM-EDX) dan Analisis Fouriere Transformi Infra Red (FTIR).
Pengenalan ecoprint guna meningkatkan keterampilan siswa dalam pemanfaatan bahan alam Susanto, Nindita Clourisa Amaris; Latief, Madyawati; Puspitasari, Ratih Dyah; Bemis, Restina; Heriyanti, Heriyanti
Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Vol 4 No 1 (2021)
Publisher : University of Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jipemas.v4i1.8974

Abstract

Ecoprint is a technique for printing colors and shapes on fabric using natural materials. Ecoprint techniques have been introduced to junior high school students because they can capture the material and teacher's instructions independently, think critically and creatively. The purpose of the ecoprint introduction activity is to provide knowledge about ecoprint and students' skills in utilizing local potential through natural materials or plants around the school. The methods used are lectures, demonstrations, practice, and evaluation. The questionnaires and direct observations on ecoprint products were used as evaluations for this activity. Students have been able to print motifs and colors from leaves and flowers on a cloth to produce ecoprint products according to their respective creativity. 
Microencapsulation of Fermented Red Palm Oil with L. casei as Nutracetical Source Hertanti, Hertanti; Nuralang, Nuralang; Susanto, Nindita Clourisa Amaris; Tarigan, Indra Lasmana; Nelson, Nelson
Jurnal Rekayasa Kimia & Lingkungan Vol 17, No 2 (2022): Jurnal Rekayasa Kimia & Lingkungan (December, 2022)
Publisher : Chemical Engineering Department, Syiah Kuala University, Banda Aceh, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23955/rkl.v17i2.27110

Abstract

Red Palm Oil (RPO) is the result of refining from Crude Palm Oil (CPO) which still maintains a high level of phytonutrients that are beneficial for health. The benefits of RPO can be used as a nutraceutical source, because RPO acts as a provitamin A and vitamin E. The addition of Lactic Acid Bacteria (LAB) in a product functions as a probiotic with metabolite activity that can inhibit pathogenic microorganism thereby increasing the durability of a product. The addition of LAB to RPO is expected to increase the nutraceutical value by adding probiotic properties to RPO products. Microencapsulation technology can protect the bioactive content of essential oils against unwanted chemical interactions with other components and provide increased stability during processing. This research is expected to be able to provide information about the potential raw material of fermented RPO as a nutraceutical source by showing the profile of RPO before and after the fermentation process, chemical and physical properties of the microencapsulant. The microencapsulation technique used is the extrusion method. Fermentation of the bioactive compound ingredients in RPO using L. casei has a significant effect. RPO after fermentation using L. casei (Red-PalmZym) produces major compounds in the form of 9-Octadecenoic acid, methyl ester, (E)- Fermentation of RPO with L. casei increases the components of chemical compounds contained therein. The stability of the RPO microencapsulated before fermentation provided an effective protection against oxidative damage to the oil and proved that the microencapsulation process can reduce the level of damage to the oil.
Sosialisasi Penurunan Tekanan Darah dengan Terapi Komplementer Herbal “TeJiMa” dan Senam Hipertensi Susanto, Bela Novita Amaris; Megananda, Nadya Karlina; Aderita, Novi Indah; Susanto, Nindita Clourisa Amaris
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 7, No 2 (2024): Volume 7 No 2 2024
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v7i2.13063

Abstract

ABSTRAK Hipertensi termasuk kategori penyakit muncul dengan gejala maupun tanpa gejala. Biasanya, penderita tidak menyadari bahwa dirinya mengalami hipertensi sampai menyadari adanya komplikasi hipertensi. Kelalaian pengobatan maupun pengobatan yang tidak teratur menjadi salah satu penyebab sulitnya hipertensi dikendalikan. Tujuan kegiatan ini untuk memberikan sosilisasi ke masyarakat penderita hipertensi tentang terapi komplementer dengan konsumsi minuman herbal dan senam hipertesi. Metode yang digunakan adalah sebelum dan sesudah sosialisasi dilakukan pengecekan tekanan darah, dilanjutkan kegiatan berupa terapi aktivitas senam bersama, setelah itu dilakukan sosialisasi dan minum bersama “TeJiMa”, dilanjutkan dengan manjawab pertanyaan dari peserta. Capaian keberhasilan kegiatan ini yaitu peserta terlihat fokus mendengarkan dan mengikuti kegiatan, terdapat penurunan tekanan darah setelah konsumsi minuman herbal “TeJiMa” dan senam hipertensi. Harapannya bagi penderita hipertensi dapat menjadikan minuman herbal “TeJiMa” sebagai terapi tambahan dalam penatalaksanaan penurunan tekanan darah. Kata Kunci: Hipertensi, Bunga Telang, Jintan Hitam, Senam Hipertensi  ABSTRACT Hypertension is a category of disease that appears with or without symptoms. Usually, sufferers do not realize that they have hypertension until they become aware of the complications of hypertension. Neglect of treatment or irregular treatment is one of the reasons why hypertension is difficult to control. The aim of this activity is to provide outreach to people suffering from hypertension about complementary therapy by consuming herbal drinks and hypertension exercises. The method used was before and after the socialization, blood pressure was checked, followed by activities in the form of group exercise therapy activities, after that socialization was carried out and drinking with "TeJiMa", followed by answering questions from the participants. The success of this activity was that the participants seemed focused on listening and participating in the activity, there was a reduction in blood pressure after consuming the herbal drink "TeJiMa" and hypertension exercises. The hope is that hypertension sufferers can use the herbal drink "TeJiMa" as additional therapy in the management of lowering blood pressure.Keywords: Hypertension, Butterfly Flower, Black Cumin, Hypertension Gymnastics
TRANSDERMAL PATCH PILIS FROM TURMERIC RHIZOME AND BLACK SEEDS FOR TREATMENT BASED ON ETHNOPHARMACY Susanto, Nindita Clourisa Amaris; Sawitri, Arinda Handiyah; Muslimah, Intan
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 11 No. 2 (2024)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jbbi.2024.4870

Abstract

Pilis, a traditional product containing various herbal ingredients, is currently less desir-able due to its impractical and unfashionable method of application. Pilis is used to treat dizziness, pain, eye fatigue, encephalitis in children, fever, and to aid recovery for mothers after childbirth. However, pilis also carries risks related to uncontrolled dosage and contamination, particularly from chemical or heavy metal pollutants, which may cause toxic reactions. To mitigate these risks, pilis should be used in recommended doses and produced under clean and safe conditions. This research aimed to provide the innovation of patches as an alternative treatment to increase attractiveness and control the active substances released and delivered for a long time. Transdermal patches are made from a combination of turmeric and black seed containing flavonoid active metabolite compounds, namely curcumin, carotenoids, quercetin, kaempferol, and apigenin. The combination has a synergistic effect that can increase total flavonoid levels and the therapeutic effect of pilis. The method used in this research was litera-ture review and data analysis. The results showed the effect of transdermal patch pilis from the combined extracts added to the formula in vitro and in vivo using animal tests. In conclusion, transdermal patch pilis has prospects as a topical treatment based on the combination of an active delivery system with a patch and metered dose system.
Green Synthesis of Ag/Chitosan Nanoparticles using Avocado Leaves Bioreductor (Persea americana Mill.) as a Nitrite Colorimetry Detector Lestari, Nani; Puspitasari, Ratih Dyah Puspitasari; Susanto, Nindita Clourisa Amaris; Tarigan, Indra Lasmana; Nelson, Nelson
Chempublish Journal Vol. 9 No. 2 (2025): Chempublish Journal (July - December)
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/chp.v9i2.46583

Abstract

Urinary tract infection (UTI) is one of the most common types of infection caused by the growth of microorganisms in the human urinary tract. Nitrite can be detected using spectroscopy, electrochemistry, chemiluminescence, chromatography, capillary electrophoresis, and flow injection analysis methods. However, this method takes quite a long time. So, this method is not suitable for rapid screening because it requires time for bacterial incubation and adequate sample preparation. So, there is a need for a fast-screening method that can diagnose UTIs through a nitrite colorimetric sensor. The colorimetric method is based on nanoparticles, which are relatively cheap and can provide visual and rapid detection. Nitrite is an indicator in diagnosing UTI. This research aims to determine the synthesis of Ag nanoparticles using avocado leaf bio-reductors (Persea americana Mill.) and chitosan as a stabilizer, which can be used as a colorimetric nitrite detector to minimize the use of dangerous and environmentally unfriendly inorganic materials. Characterization and analysis in this research used a UV-Vis spectrophotometer, FT-IR (Fourier Transform Infra-Red), and PSA (Particle Size Analyzer). The Ag nanoparticle synthesis process was carried out by varying the bioreductant volume, synthesis time, and chitosan concentration. It was found that the optimum synthesis time was 4 hours with an SPR value of 428 nm, an absorbance of 2.112 and a nanoparticle size. Apart from that, the optimum concentration of chitosan was obtained at a concentration of 2.5% with an SPR of 435 nm and an absorbance of 1.341 with a nanoparticle size. The results obtained from AgNPs/chitosan as a colorimetric nitrite detector showed a color change to purple with an LOD value of 0.1303 µM and an LOQ of 0.4345 µM. Keywords: Ag Nanoparticles; Avocado Leaveas; Colorimetry; Nitrite.
Co-Authors Aderita, Novi Indah Adriliana, Zairaini Adriliana Aminuyati Ananda, Hertanti Dwi Anif Nur Artanti, Anif Nur Aptika Oktaviana Trisna Dewi Ardhica, Jammes Darojati, Ulfa Afrinurfadhilah Diah Riski Gusti ERMAWATI, DIAN EKA Fajri, Nadiatul Fikriansyah, Muhammad Hanifah, Fitria Lidini Hanuriansyah, Yavi Hapsari, Aulia Ratri Heriyanti Heriyanti, Heriyanti Hertanti, Hertanti Heru Sasongko Indra Lasmana Tarigan Madyawati Latief Megananda, Nadya Karlina Megasari, Anis Laela Meitasari, Annisa Diyah Meitasari, Annisa Diyan Muslimah, Intan Nafisa, Fadhila Dian Nani Lestari Nelson Nelson Nelson Nuralang nuralang, nuralang Pradina, Armitha Dea Prasetio, M. Reza Prasetio, Muhamad Reza Prastia, Echa Hana Puspitasari, Ratih Dyah Puspitasari, Ratih Dyah Puspitasari Rahayu Rahayu Restina Bemis, Restina Rochmani, Sholichah Rohmani, Sholicha Sawitri, Arinda Handiyah Sholichah Rohmani, Sholichah siti nurkhasanah Susanto, Bela Novita Amaris Sutrisno, Sutrisno untari, meta kartika Utami, Diyah Tri Wulan Safitri, Wulan Zulpadly, M. Fiqri Zulpadly, Muhammad Fiqri