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All Journal Jurnal Kedokteran Brawijaya Jurnal Respirologi Indonesia Jurnal Respirasi (JR) Malang Respiratory Journal Jurnal Klinik dan Riset Kesehatan Asian Journal of Health Research
Tantular, Rezki
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Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Survival Rate of Lung Adenocarcinoma Patients Receiving EGFR - Tyrosine Kinase Inhibitor Targeted Therapy Setyawan, Ungky Agus; Tantular, Rezki; Bahar, Chaerani
Jurnal Kedokteran Brawijaya Vol. 32 No. 3 (2023)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2022.032.03.5

Abstract

Globally, lung cancer is by far the leading cause of death by cancer-which contribute to 2.094 million death-with the highest toll from cancer being 1.8 million. Currently, lung cancer therapy has developed from chemotherapy to targeted therapy, such as Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor (EGFR-TKI). This study aimed to assess the survival rate of adenocarcinoma cell lung cancer patients who received EGFR-TKI therapy at the Pulmonary Clinic of Dr. Saiful Anwar General Hospital Malang. This study was a retrospective study using patient medical records between 2017 and 2020. The data were processed and analyzed using the Chi-Square test. The number of samples was 117 patients consisting of 63 patients receiving Gefitinib therapy, 36 patients receiving Afatinib therapy, and 18 patients receiving Erlotinib therapy. There were no significant differences between variables of age, sex, smoking history, stage, and exon mutations with 1-year survival. Gefitinib therapy has a higher average survival time than Afatinib and Erlotinib. However, the 1-year survival rate (YSR) was highest on Afatinib. The Middle Survival (MS) of the three regimens is almost the same, about 300 days. Statistical data showed no relationship between survival and the treatment regimen given (p=0.187). The most common side effect of TKI is skin rash. This research should be carried out with a larger sample to minimize bias.
Overview of Tuberculosis Knowledge among SMK Telkom Malang Students R Sugiri, Yani Jane; Tantular, Rezki; Binharyanto, Adlan Pratama; Pratiwi, Eka; Muhammad, Iqbal; Asyari, Claudia Herda; Dini, Zata; Primaputri, Cindy Carissa; Lyono, Albert; Susanti, Lia; Delfianto, Dwiroza; Aprilen, Nisa; Suardana, I Made; Murti Dewi, Dian Ayu; Wikamto, Rifka
Jurnal Kedokteran Brawijaya Vol. 33 No. 4 (2025)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2025.033.04.6

Abstract

Tuberculosis has emerged as a major global health challenge. Public knowledge about TB is crucial for its prevention, early detection, and management. Research conducted by the World Health Organization indicates that a good level of knowledge about Tuberculosis among the public can significantly enhance symptom recognition, timely medical care, and reduce the stigma. This study aims to describe the TB knowledge of SMK Telkom Malang students. A quasi-experimental pretest-posttest design was conducted involving 415 students, of whom 336 completed both assessments. TB knowledge was measured using a 10-item validated questionnaire and categorised as good, sufficient, or poor. The Wilcoxon signed-rank test was used for statistical analysis. They were then given health education about TB, after receiving health education about TB, 69 students did not consent to continue the study or complete the posttest and were therefore excluded, leaving 336 students as sample. Pretest demonstrated 225 students (67%) with good knowledge, 93 students (27,7%) with sufficient knowledge, and 18 students (5,3%) with poor knowledge, the overall median was 80, while posttest analysis revealed 264 students (78.6%) with good knowledge, 66 students (19.6%) with sufficient knowledge, and 6 students (1,8%) with poor knowledge, the overall median was 90 . The scores were compared using the Wilcoxon test with significantly improved score with a p-value of <0.001. In conclusion, health education significantly improved TB knowledge among students. Continued efforts to integrate TB education in schools are recommended to support TB control strategies.
Co-Authors Abdul, Haris Andreas, Santoso Aprilen, Nisa Arinto Yudi Ponco Wardoyo Asyari, Claudia Herda Bahar, Chaerani Binharyanto, Adlan Pratama Chozin, Iin Noor Delfianto, Dwiroza Dini Rachma Erawati Dini, Zata Djajalaksana, Susanthy Eka Pratiwi Fadli, M Luqman Falyani, Silvy Amalia I MADE SUARDANA I Wayan Agung Indrawan Iqbal Muhammad Jane, Sugiri Kristo, Kurniawan Listyoko, Aditya Sri Lyono, Albert Mafisah, Saidah Maulana, Uray Riki Arif Murti Dewi, Dian Ayu Nanik Setijowati Permana, Deden Prabowo, Adityo Pratama, Anugerah Justi Primaputri, Cindy Carissa R Sugiri, Yani Jane R. Sugiri, Yani Jane Rahayu Sartono, Teguh Sartono, Teguh Rahayu Setyawan, Ungky Agus Setyo Yudhanto, Hendy Sugiri, Yani Jane Rosihaningsih Susanti, Lia Syahrul Chilmi, Syahrul Widowati, Ayu Rizky Wikamto, Rifka Yusdianto, Adrian Yusuf, Mustofa