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Yusneli, Yusneli
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GAMBARAN KADAR KREATININ PADA PENDERITA HIPERTENSI DI RUMAH SAKIT ISLAM SITI KHADIJAH PALEMBANG Amalia, Ruhalida Okta; Yusneli, Yusneli; Siregar, Sri Sulpha; Febriyani, Erisa; Syailendra, Anton
Journal of Medical Laboratory and Science Vol 3 No 2 (2023): JMLS: Journal of Medical Laboratory and Science
Publisher : Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36086/medlabscience.v3i2.1968

Abstract

Latar Belakang: Hipertensi atau tekanan darah tinggi ditandai dengan meningkatnya tekanan darah pada dinding pembuluh darah arteri. Tekanan darah yang melebihi nilai 140/90 mmHg dapat mengakibatkan aliran darah pada ginjal terganggu. Apabila salah satu faktor pendukung kerja ginjal seperti aliran darah ke ginjal, jaringan ginjal atau saluran pengeluaran ginjal terganggu maka dapat merusak fungsi ginjal. Menurunnya kerja ginjal akan menyebabkan nilai kadar kreatinin meningkat. Tujuan Penelitian: Untuk mengetahui gambaran kadar kreatinin pada penderita Hipertensi di Rumah Sakit Islam Siti Khadijah Palembang tahun 2022. Metode Penelitian: deskriptif dengan pendekatan cross sectional jumlah sampel 100 pasien. Hasil Penelitian: Didapatkan hasil 47 pasien (47,0%) yang memiliki kadar kreatinin normal dan yang memiliki kadar kreatinin tidak normal sebanyak 53 pasien (53,0%). Pada laki-laki didapatkan hasil kadar kreatinin tidak normal sebanyak 30 pasien (75,0%), sedangkan pada perempuan didapatkan hasil kadar kreatinin tidak normal sebanyak 23 pasien (38,3%). Kategori Umur berisiko (≥ 40 tahun) didapatkan hasil kadar kreatinin tidak normal sebanyak 48 pasien (53,9%) dan umur tidak berisiko (< 40 tahun) didapatkan hasil kadar kreatinin tidak normal sebanyak 5 pasien (45,5%). Berdasarkan derajat tekanan darah pada hipertensi tipe I kadar kreatinin tidak normal sebanyak 35 pasien (66,0%) dan pada hipertensi tipe II kadar kreatinin tidak normal sebanyak 18 pasien (34,0%). Kesimpulan: kadar kreatinin pada penderita hipertensi cenderung tidak normal dengan rerata sebesar 61,97%. Saran : bagi penderita hipertensi terutama penderita tipe I dan II seyogyanya rutin melakukan pemeriksaan kadar kreatinin untuk memantau gangguan ginjal serta efek samping hipertensi. Kata Kunci: Kreatinin, ginjal, hipertensi
KOMBINASI KITOSAN DAN Lactobacillus acidophilus SEBAGAI ANTIBAKTERI Escherichia coli Febriyani, Erisa; Yusneli, Yusneli; Siregar, Sri Sulpha; Handayani, Handayani; Afriayani, Iis
Journal of Medical Laboratory and Science Vol 4 No 1 (2024): JMLS: Journal of Medical Laboratory and Science
Publisher : Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36086/medlabscience.v4i1.2147

Abstract

ABSTRACT Background: Chitosan is a prebiotic obtained from fishery waste raw materials such as shrimp heads and crab shells which are abundant in Indonesia. Prebiotics are indigestible ingredients that produce beneficial effects on the host by selectively stimulating the growth of one or more specific bacteria. LAB from the genera Lactobacillus and Bifidobacterium have potential as probiotic agents that are beneficial for human and animal health. The amount of probiotics can be optimized by using prebiotics. The synergistic concept between probiotics and prebiotics is known as synbiotics. This research aims to see the effect of the combination of chitosan and Lactobacillus acidophilus on the growth of Escherichia coli bacteria in Vivo. Methods: E. coli in cecum duck was determinant by plate count method. Results: The average of E. coli content in the cecum of pegagan duck were : 40.00; 78.33; 21.67; 19.33 dan 11.00x105 CFU/mL for treatment A (control), B, C, D, E, F, G, and H respectively. Conclusion: The results showed that the treatment had significant effect (P<0,05) on E. coli. Keywords : L. acidophilus sp, Chitosan 0,2%, E. coli
Co-Authors Afriayani, Iis Aisy, Andind Rahadatul Amalia, Ruhalida Okta Amin, Maliha Asrori Asrori Basa, Itail Husna Dani, Hamril Erwin Edyansyah, Erwin Fandianta, Fandianta Febriani, Erisa Febriyani, Erisa Garini, Ardiya Handayani Handayani Harianja, Sri Hartini Hermansyah, Herry Hetty Ismainar Jepisah, Doni Karwiti, Witi Lestari, Wuni Sri Maksuk Marlina, Hastuti Maulina, Aura Nasrazuhdy, Nasrazuhdy Navianti, Diah Nurhayati Nurhayati Nurhidayah Nurhidayah Nyayu Fauziah Zen, Nyayu Fauziah Oktavia, Tiara Rahmawati, Ully Refai, Refai Safura, Intan SEPTI WULANDARI Siregar, Sri Sulpha Sudarti Sudarti Syailendra, Anton Yessi Harnani