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All Journal JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA JURNAL FARMASIMED (JFM) Majalah Farmasetika Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Penelitian Farmasi dan Herbal Journal of Fundamental and Applied Pharmaceutical Science Medical Sains : Jurnal Ilmiah Kefarmasian RENATA Jurnal Pengabdian Masyarakat Kita Semua CERATA Jurnal Kesehatan dr. Soebandi Prosiding Seminar Nasional Unimus Medical Sains : Jurnal Ilmiah Kefarmasian Kunir: Jurnal Farmasi Indonesia (KJFI) Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan JPEMAS: Jurnal Pengabdian Kepada Masyarakat Journal of Community Research and Engagement
Fransisca Dita Mayangsari
Fakultas Ilmu Kesehatan, Universitas Muhammadiyah Lamongan, Jawa Timur, Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Kajian Literatur: Aplikasi Sejumlah Metode Ekstraksi Konvensional untuk Mengekstraksi Senyawa Fenolik dari Bahan Alam Arrofiqi, Mochammad Rasyad; Sakti, Aditya Sindu; Mayangsari, Fransisca Dita
Jurnal Penelitian Farmasi Dan Herbal Vol 7 No 1 (2024): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v7i1.1972

Abstract

This literature review explores various conventional extraction methods utilized to extract phenolic compounds from natural materials. Phenolic compounds, known for their significant antioxidant, anti-inflammatory, and anticancer properties, are crucial bioactive molecules found in plants. The study examines methods such as maceration, percolation, reflux, Soxhlet, digestion, infusion, and decoction, highlighting their efficiencies, advantages, and limitations. The findings suggest that while conventional methods are cost-effective and accessible, they often require longer extraction times and may lead to thermal degradation of sensitive compounds
Pengaruh Probiotik Terhadap Karakteristik dan Stabilitas Fisik Serum NLC Koenzim Q10 Rohmah, Habibatur; Dwi Pratiwi, Elasari; Dita Mayangsari, Fransisca
Majalah Farmasetika Vol 10, No 1 (2025)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/mfarmasetika.v10i1.49478

Abstract

Probiotik merupakan mikroorganisme yang memiliki sifat antioksidan yang dapatberperan sebagai anti aging dan memperbaiki skin barrier. Penelitian tentangpenggunaan probitok masih minim dilakukan, sehingga pada penelitian ini probiotikdiformulasikan kedalam sediaan serum NLC Koenzim Q10 sebagai second activeingredient. Penelitian ini bertujuan untuk menganalisis pengaruh variasi kosentrasiprobiotik terhadap serum yang mengandung NLC Koenzim Q10 terhadap karakteristikdan stabilitas fisik. Variasi konsentrasi probiotik yang diamati yaitu 0% (F0), 2% (F1)dan 6% (F2). NLC Koenzim Q10 dibuat dengan High Shear Homogenization,selanjutnya dicampur dengan basis serum dan probiotik. Setelah itu, dilakukankarakteristik dan stabilitas fisik secara real-time selama 12 minggu dengan parameterorganoleptis, homogenitas, pH dan viskositas. Hasil pengujian karakteristik fisikmenunjukkan bahwa ketiga formula memiliki warna, bentuk dan homogenitas yangsama. F0 memiliki aroma khas lemak seperti NLC, sedangkan F1 dan F2 memilikiaroma asam khas probiotik. Nilai pH dan viskositas F0 lebih tinggi dibandingkan F1 danF2, namun masih memenuhi spesifikasi yang ditetapkan. Pengujian stabilitas fisikmenunjukkan bahwa ketiga formula tetap stabil pada aspek warna, bentuk, danhomogenitas. Namun, aroma pada F1 dan F2 semakin intens, pH mengalamipenurunan dan viskositas mengalami peningkatan. Dengan demikian, dapatdisimpulkan bahwa probiotik mempengaruhi aroma pH dan viskositas, tetapi tidakmempengaruhi warna, bentuk, dan homogenitas sediaan.
Evaluation of Skin Irritation Level and Effectiveness of Foot Sleeping Mask Containing Tengkawang Fat in Nanostructured Lipid Carriers System Fidayanti, Ayu; Mayangsari, Fransisca Dita; Pratiwi, Elasari Dwi
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2608

Abstract

One of the export commodities from the Non-Timber Forest Products (NTFP) group is tengkawang fruit. This fruit can be processed into fat which has properties similar to cocoa butter. The advantage of this fat compared to cocoa butter is that the price is relatively cheaper. However, the use of tengkawang fat in cosmetics is not widely known. Therefore, researchers are interested in developing cosmetic products based on tengkawang fat to treat xerosis of the feet. To increase occlusivity, tengkawang fat is formulated into an NLC (Nanostructured Lipid Carriers) system. In this research, a foot sleeping mask product was made containing NLC tengkawang fat with the addition of gel (to improve viscosity) and sweet orange oil (to improve aroma). The aim of this research was to determine the irritation skin level and effectiveness of moisturizing the skin of the soles of the feet from a foot sleeping mask containing NLC tengkawang fat. The results of the physical characteristics test show that the foot sleeping mask made meets the desired specifications. The results of skin irritation tests with 35 panelists showed that there was no redness or edema on the panelists' skin during 24, 48 and 72 hours of observation. The results of the moisture effectiveness test showed that the average moisture content of the soles of the panelists' feet on day 0 was 34.531%, while on day 28 (4 weeks) it was 42.815%. There was an increase in humidity of 8.284% during 4 weeks of use. The conclusion of this research is that a foot sleeping mask containing Tengkawang fat NLC can increase the moisture of the skin of the soles of the feet by 8.284% during 4 weeks of use.
Edukasi Jajanan Sehat Di SDN Banjarmadu Oleh Tim KKN (Kuliah Kerja Nyata) Dari Universitas Muhammadiyah Lamongan Mayangsari, Fransisca Dita; Fadhilah, Indi Ulul; Rakhmawati, Adinda; Afrianti, Diah Laili Dwi; Azmy, Dymas Zahruddin
JPEMAS: Jurnal Pengabdian Kepada Masyarakat Vol. 1 No. 1 (2022): JPEMAS : Jurnal Pengabdian Kepada Masyarakat
Publisher : Yayasan Pendidikan Tanggui Baimbaian

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71456/adc.v1i1.35

Abstract

Anak usia sekolah (6-12 tahun) membutuhkan asupan gizi yang cukup karena pada usia ini sedang dalam masa pertumbuhan. Anak-anak menghabiskan sebagian besar waktunya di sekolah. Pada umumnya, di sekolah atau di sekitar sekolah banyak sekali penjual makanan yang menarik perhatian anak-anak, seperti es krim, telur gulung, dan lain-lain. Namun, tidak semua makanan yang dijual di sekolah atau di sekitar sekolah adalah jajanan atau makanan yang sehat. Pada beberapa survei yang pernah dilakukan, masih ada jajanan sekolah yang mengandung BTP (Bahan Tambahan Pangan) berbahaya seperti boraks, formalin dan rodamin. Hal inilah yang mendasari tim KKN (Kuliah Kerja Nyata) dari Universitas Muhammadiyah Lamongan mengadakan penyuluhan mengenai jajanan sehat di SDN Banjarmadu, Kecamatan Karanggeneng, Kabupaten Lamongan, Provinsi Jawa Timur. Penyuluhan ini diharapkan dapat membuat siswa-siswa SDN Banjarmadu dapat memiliki kebiasaan yang baik dalam membeli jajanan di sekolah. Penyuluhan ini terdiri dari 3 tahap, yaitu tahap persiapan, pelaksanaan dan evaluasi. Pada tahap persiapan, dilakukan analisa permasalahan, pencarian solusi dan melakukan izin kegiatan. Tahap selanjutnya yaitu pelaksanaan penyuluhan mengenai jajan sehat menggunakan metode ceramah. Tahap terakhir yaitu tahap evaluasi yang dilakukan menggunakan metode kuis edukatif. Berdasarkan hasil evaluasi, disimpulkan bahwa Siswa-siswi SDN Banjarmadu sangat antusias dengan acara penyuluhan jajan sehat yang telah dilakukan oleh tim KKN Universitas Muhammadiyah Lamongan. Para siswa-siswi juga cukup memahami materi yang telah disampaikan oleh tim KKN. Hal ini dibuktikan dengan banyaknya siswa-siswi yang sangat aktif menjawab pertanyaan yang diajukan oleh tim KKN saat sesi kuis edukatif.
THE EFFECT OF LAVENDER OIL CONCENTRATION ON PREFERENCE AND SKIN IRRITATION OF NIGHT BODY LOTION CONTAINING NANOSTRUCTURED LIPID CARRIERS-UBIQUINONE Mayangsari, Fransisca Dita; Sakti, Aditya Sindu; Khotimah, Khusnul
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 10 No 3 (2025)
Publisher : Universitas Muhammadiyah Ahmad Dahlan Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v10i3.1344

Abstract

Lavender Oil (LO) has a calming scent and antioxidant activity. Therefore, this oil has potential as a fragrance and second active ingredient in Night Body Lotion (NBL) that contained Coenzyme Q10 (CoQ10) loaded Nanostructured Lipid Carrier (NLC) systems.  This study aims to observe the effect of LO’s concentration on the physical characteristics, consumer preference level, and skin irritation of NBL that contained NLC-CoQ10. There are three formulas observed in this study, namely F0 (0% LO), F1 (2% LO), and F2 (4% LO). The physical characteristics assessed included organoleptic, homogeneity, pH, spreadability, and viscosity.  In vivo skin irritation tests observe erythema and edema on the skin of a white rat. In a consumer preference test, the panelists assess the organoleptic properties of F0, F1, and F3 using a 7-point hedonic scale. Based on the physical characteristic test, it is known that the three formulas have the same color, consistency, homogeneity, and spreadability value. The difference between the three formulas lies in their aroma. F0 is unscented; F1 and F2 have a lavender scent. All formulas have a pH in the range of 5.89-6.06. Statistically, increasing the concentration of LO decreases the pH of NBL. The three formulas have a viscosity in the range of 2.140–2.890 cP. Statistically, the viscosity of NBL increased with the increase in LO concentration. Based on the skin irritation test, it is known that all formulas are non-irritating. Based on preference level analysis, the most preferred formulas based on their scent are F1 and F2.
DAGUSIBU (OBTAIN, USE, STORE, AND DISPOSE): DRUG MANAGEMENT COUNCELLING FOR THE ELDERLY Hilda Rohadatul Aliyah; Zahro Aisyi Khaddah; Yulia Retno Agustin; Azwar Mirza Al Fath; Putri Wulandari; Fransisca Dita Mayangsari
Journal of Community Research and Engagement Vol. 2 No. 1 (2025): MAY
Publisher : Universitas Muhammadiyah Lamongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.38040/jcore.v2i1.1148

Abstract

Background: The lack of public awareness regarding proper medicine management contributes to irrational drug use and improper disposal, which can harm the environment, water sources, and ecosystems. Observations in Miru Village, Sekaran District, Lamongan Regency indicate that the community, particularly the elderly, has never received education on the principles of DAGUSIBU (Obtain, Use, Store, Dispose). Therefore, educating the public, especially the elderly, is essential to enhance their knowledge of safe and effective drug management. Objective: This initiative aims to improve the elderly’s understanding of how to obtain, use, store, and dispose of medicines properly. Method: Educational sessions were conducted using lectures, question-and-answer discussions, and visual aids including posters and brochures. These sessions took place at Pasadena Pharmacy, Miru. To assess the program’s effectiveness, participants completed pre-test and post-test assessments, along with satisfaction questionnaires. Results: Shows an increase in knowledge from pretest and posttest where the pretest results before the presentation of the material were only 20% then after the presentation of the material the posttest value increased to 95% until it reached 100%. In addition, the satisfaction of most participants expressed satisfaction with the presentation of the material that had been done. Conclusion: This community service program has proven to be effective in increasing public knowledge about DAGUSIBU. Improved understanding of proper medicine management can enhance public health and promote safer drug use, ultimately reducing the risks associated with improper medication practices.
Tingkat Pengetahuan Masyarakat Tentang Obat Tradisional di Desa Temenggungan Kecamatan Cepu Kabupaten Blora Jannah, Miftakhul; Kusumo, Djati Wulan; Mayangsari, Fransisca Dita
KUNIR: JURNAL FARMASI INDONESIA Vol 3 No 2 (2025): NOVEMBER
Publisher : Program Studi Farmasi (S-1), Fakultas Ilmu Kesehatan, Universitas Bhamada Slawi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36308/kjfi.v3i2.852

Abstract

Penggunaan obat tradisional masih menjadi bagian penting dari praktik kesehatan masyarakat di pedesaan Indonesia, namun pemahaman terkait aspek keamanan, batas konsumsi, dan regulasi masih terbatas. Penelitian ini bertujuan mengukur tingkat pengetahuan masyarakat Desa Temenggungan tentang obat tradisional serta hubungan karakteristik responden terhadap tingkat pengetahuan tersebut. Penelitian kuantitatif dengan desain analitik korelasi ini melibatkan 89 responden yang dipilih secara purposive dan stratified random sampling. Instrumen berupa kuesioner terstruktur 15 item pertanyaan yang telah diuji validitas menggunakan korelasi Pearson ( r hitung 0,612–0,863 > r tabel 0,361) dan reliabilitas dengan Cronbach’s Alpha (0,939). Analisis data dilakukan secara deskriptif dan inferensial (uji chi-square). Temuan penelitian ini mengindikasikan bahwa mayoritas responden memiliki pengetahuan kategori cukup (69,7%), diikuti kurang (21,3%) dan baik (9%). Pekerjaan berhubungan signifikan dengan tingkat pengetahuan (p=0,009), sedangkan umur (p=0,372) dan pendidikan (p=0,720) tidak menunjukkan hubungan signifikan. Secara umum, masyarakat di Desa Temenggungan memiliki pengetahuan yang berada pada kategori cukup dengan kekuatan pada pemahaman definisi dan manfaat umum, namun lemah pada aspek keamanan, batas konsumsi, dan literasi regulasi. Edukasi berbasis bukti ilmiah diperlukan untuk meningkatkan penggunaan obat tradisional yang aman dan tepat.
UJI KARAKTERISTIK FISIK DAN HEDONIK DARI ANTIAGING SLEEPING MASK DENGAN EKSTRAK KULIT BUAH DELIMA MERAH Fransisca Dita Mayangsari; Djati Wulan Kusumo; Zurotul Muarifah
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.640

Abstract

ABSTRACT Red pomegranate peel extract (RPPE) contains ellagitannin. This compound has an antioxidant effect. Therefore,this extract has good potential as an active ingredient in anti-aging cosmetics. However, applying the extract directly to the skin is inconvenient. So in this study RPPE was formulated into a sleeping mask. This study aims to analyze the effect of variations in the concentration of RPPE in sleeping masks on physical characteristics and the level of preference/hedonic. RPPE concentration observed was 2.5% (F1) ; 5% (F2) ; 7.5% (F3). Characteristic tests include organoleptic, pH value, visual homogeneity, consistency and viscosity. Parameters analyzed in the hedonic test include texture, color, and aroma. The organoleptic and homogeneity were analyzed descriptively. The test data for pH and viscosity were analyzed statistically using the One Way ANOVA method. The results of the hedonic test were analyzed statistically using the univariate method. Based on the results of the organoleptic test, it is known that F1 have a light brown color, F2 is brown, and F3 is dark brown. The third formula is visually homogeneous. The higher the concentration of RPPE, the lower the pH value and viscosity of the preparation. Increasing the concentration of RPPE reduce consistency. This study concluded that the concentration of RPPE affects the physical properties of the aspects of color, consistency, pH, and viscosity. The concentration of RPPE also affects the level of preference of the panelists. Most of the panelists prefer the color and texture of the sleeping mask that contains low concentration of RPPE (2.5%). Keywords : Physical Characteristics ; Hedonic; Sleeping Mask ; Red Pomegranate Peel Extract
KOMBINASI MINYAK KULIT JERUK MANIS DAN PEPERMIN SEBAGAI PENGAROMA ALAMI PADA SEDIAAN DEODORAN KRIM: EVALUASI KARAKTERISTIK FISIK DAN IRITASI KULIT Mayangsari, Fransisca Dita; Elasari Dwi Pratiwi; Muhammad Arendra Ardiansyah
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 11 No. 2 (2025): Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v11i2.948

Abstract

Sweet orange peel oil (MJ) and peppermint oil (MP) are essential oils. The MJ contained mainly limonene, while the MP contained mainly menthol. These compounds give MJ and MP their distinctive aromas but can also potentially cause skin irritation, especially when used in high concentrations. The purpose of this study was to observe the effect of adding a combination of essential oils (MJ and MP) at a concentration of 3% on the physical characteristics and skin irritation levels of cream deodorants. The ratios of MJ:MP added were 0:0 (F0), 100:0 (FA), 50:50 (FB), and 0:100 (FC). In the physical characteristic test, observations included pH, organoleptic, viscosity, and spreadability. In the irritation test, observations included erythema and edema on the skin of white rat. Based on the organoleptic test, it is known that F0 was odorless, FA had the aroma of MJ, FB had the aroma of MP with a little MJ, and FC had the aroma of MP. All four formulas were white in color and had a semi-solid consistency. They had a pH between 5.27-5.68. The formula with the highest pH was F0. All four formulas had a spreadability value between 5.20-5.53. These values ??were not significantly different. All four formulas had a viscosity value between 14,066-14,980 cP. These values ??were not significantly different. The results of skin irritation observations showed that all formulas had a primary irritation index score of 0. The study concluded that the ratio of MJ and MP affected the aroma and pH of the cream deodorant but did not affect the color, consistency, viscosity, and spreadability. None of the formulas causes skin irritation.
The Effect of Essential Oil Types on The Physical Characteristics and Consumer Preference Level of Antiaging Body Lotion that Contain NLC-Coenzyme Q10 Fransisca Dita Mayangsari; Khusnul Khotimah; Asyalafia
Jurnal Kesehatan dr. Soebandi Vol 11 No 2 (2023): Jurnal Kesehatan dr. Soebandi
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/jkds.v11i2.487

Abstract

Lavender oil and lime oil contain linalool which has a relaxing effect. This oil has potential as a fragrance in antiaging body lotion products containing Coenzyme Q10 (CoQ10) in the Nanostructured Lipid Carriers System (NLC). This study aimed to analyzed the physical characteristics and consumer preference level for anti aging body lotion containing NLC-CoQ10. NLC-CoQ10 was prepared using the High Shear Homogenization method. For F1 (Formula 1), NLC-CoQ10 is mixed with a gel base and lavender oil. For F2 (Formula 2), the type of essential oil added is lime oil. These two forms when compared with F0 (Formula 0 = formula without essential oils). The physical properties observed included organoleptic, pH, homogeneity, spreadability, and viscosity. Organoleptic test and homogeneity were analyzed descriptively. While the pH, spreadability, and viscosity were analyzed using One Way Anova. In the preference level test, the aspect that is assessed is aroma. This test was analyzed statistically using the Univariate method. Based on the physical characteristic test, it is known that the three formulas have the same color, consistency, and homogeneity. The difference between the three formulas lies in their aroma. F0 is unscented; F1 has a lavender scent; F2 has a lime scent. The viscosity of the three formulas is also different but does not affect the spreadability value. Based on the aroma preference level test, it is known that F2 has the highest value. The type of essential oil affects the aroma and level of preference of the panelists. The most preferred formula is a formula containing lime oil. Keyword: Anti-aging; Body Lotion; Koenzim Q10; Lavender Oil; Lime Oil
Co-Authors Adinda Rakhmawati Aditya Sindu Sakti Afrianti, Diah Laili Dwi Aini, Reyda Eka Ainun Filzah Fazliana Anugrahayu Harsart, Yully Arrofiqi, Mochammad Rasyad Arrohmah, Nabilah Asyalafia Asyalafia Ats-Tsaqiifah, Nadya Jauharo Aula Nurwanda, Friska Selsabillah Azmy, Dymas Zahruddin Azwar Mirza Al Fath Diah Indah Kumala Sari Diah Laili Dwi Afrianti Dwi Pratiwi, Elasari Dymas Zahruddin Azmy Elasari Dwi Pratiwi Elasari Dwi Pratiwi Elasari Dwi Pratiwi ELASARI DWI PRATIWI, ELASARI DWI Emilia Rahmawati Fadhilah, Indi Ulul Fidayanti, Ayu Habibatur Rohmah Hilda Rohadatul Aliyah I Ketut Suada Indi Ulul Fadhilah Khurin’in, Laura Ayu khusnul khotimah Khusnul Khotimah Kusumo, Djati Wulan Lailiyah, Qurrotul Mafula, Faricha Maulidah, Mufarokhah Sukma Merry Anggelya Mentari MIFTAKHUL JANNAH Muhammad Arendra Ardiansyah Nasrul Haq, Nifa’il Noorma Rosita Primanitha Ria Utami Primanitha Ria Utami Putri Gita Ayu Safitri PUTRI WULANDARI Rakhmawati, Adinda Rizka Amalia Fachriani Rohmah, Habibatur Safira Yulita Fazadini Sandrawati Sri Bintang Sahara Mahaputra Kusumanegara Tristiana Erawati Munandar Uswatun Khasanah Widji Soeratri Yulia Retno Agustin Zahro Aisyi Khaddah Zurotul Muarifah