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Journal : Journal of Comprehensive Science

Activity Test of Anti-Dandruff Shampoo Preparation of Fragrant Pandan Leaf Extract (Pandanus Amaryllifolius Roxb.) Against the fungus Malassezia Furfur Pallo, Arini Aprili; Pakan, Prisca Deviani; Indriarini, Desi; Riwu, Magdarita
Journal of Comprehensive Science Vol. 5 No. 2 (2026): Journal of Comprehensive Science
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/jcs.v5i2.4022

Abstract

Dandruff is a scalp disorder caused by Malassezia furfur fungus, often treated with anti-dandruff shampoos. However, synthetic active ingredients in such shampoos may cause side effects like scalp irritation, dryness, or allergies. As an alternative, herbal formulations using fragrant pandan leaves (Pandanus amaryllifolius Roxb.), known for their antifungal properties, can be developed. The objective of this study was to determine and analyze the best Fragrant pandan (Pandanus amaryllifolius Roxb.) leaf extract shampoo formulation and its antifungal activity against Malassezia furfur. The type of research conducted was a true experimental study with a Post-Test Only Control Group Design. In this study, there were treatment groups given a shampoo preparation of fragrant pandanus leaf extract at concentrations of 30%, 50%, and 70%, a negative control group of a shampoo base, and a positive control group of a shampoo containing 1% selenium sulfide under the brand name Selsun. The analysis used was the One-Way ANOVA test. The shampoo preparation of fragrant pandanus leaf extract demonstrated antifungal activity against Malassezia furfur, with inhibition zones obtained at a 30% concentration (15.83 mm), 50% concentration (18.68 mm), 70% concentration (21.89 mm), positive control (21.36 mm), and negative control (0 mm). The 70% Fragrant pandan (Pandanus amaryllifolius Roxb.) leaf extract shampoo preparation is the best formulation because it exhibits optimal physical characteristics and produces the greatest inhibition against Malassezia furfur.
Hubungan Letak Hemiparesis Dengan Derajat Depresi Pada Penderita Stroke Non Hemoragik di RSUD Prof. Dr. W. Z. Johannes Kupang Legoh, Christiano Yeheskiel; Louis Wungouw, Herman Pieter; Riwu, Magdarita; Deo, Dwita Anastasia
Journal of Comprehensive Science Vol. 5 No. 3 (2026): Journal of Comprehensive Science
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/jcs.v5i3.4103

Abstract

Stroke non hemoragik merupakan gangguan neurologis akibat sumbatan aliran darah otak yang sering menimbulkan hemiparesis sebagai gejala sisa. Kondisi kelemahan satu sisi tubuh ini tidak hanya berdampak pada fungsi fisik, tetapi juga berkontribusi terhadap gangguan psikologis seperti depresi. Perbedaan hasil penelitian sebelumnya mengenai kecenderungan depresi berdasarkan letak hemiparesis mendorong dilakukannya penelitian ini. Penelitian ini bertujuan menganalisis hubungan letak hemiparesis dengan derajat depresi pada penderita stroke non hemoragik di RSUD Prof. Dr. W. Z. Johannes Kupang. Penelitian menggunakan desain analitik observasional dengan pendekatan cross sectional terhadap 46 responden yang dipilih secara consecutive sampling. Derajat depresi diukur menggunakan kuesioner Hamilton Depression Rating Scale (HDRS), kemudian dianalisis secara univariat dan bivariat menggunakan uji Koefisien Kontingensi. Hasil penelitian menunjukkan mayoritas responden mengalami depresi derajat sedang (37%). Analisis bivariat menunjukkan terdapat hubungan signifikan antara letak hemiparesis dengan derajat depresi (p=0,009; p<0,05). Disimpulkan bahwa letak hemiparesis berhubungan secara bermakna dengan tingkat keparahan depresi pada pasien stroke non hemoragik, sehingga diperlukan perhatian multidisiplin dalam penanganan aspek fisik dan psikologis pasien.