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RISK FACTORS FOR PULMONARY TUBERCULOSIS COINFECTION IN HIV/AIDS PATIENTS Ildha Rosendy Kurnianda; Apriliana, Ety; Putri, Giska Tri; Wardani, Dyah Wulan Sumekar Rengganis
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1318

Abstract

Tuberculosis and HIV co-infection is a major public health problem in many parts of the world. In Indonesia, tuberculosis (TB) is an opportunistic infection that most often occurs in people living with HIV/AIDS (PLWHA). HIV infection increases susceptibility to Mycobacterium tuberculosis, thereby increasing the risk of developing TB. The World Health Organization (WHO) estimates that TB causes 13% of deaths in AIDS sufferers. Tuberculosis (TB) and HIV co-infection occurs when a person is infected with Mycobacterium tuberculosis and HIV at the same time. People with HIV have a 30 times greater risk of suffering from TB than people who are not infected with HIV. There is a significant relationship between these two infections, where each infection accelerates the development of the other infection. HIV infection can trigger reactivation of latent TB into active TB, while TB infection can worsen the clinical condition of patients who have been infected with HIV. The aim of this study was to determine various risk factors for pulmonary tuberculosis co-infection in HIV/AIDS patients. The method used is qualitative with literature study as a data collection technique. The results obtained were alcohol consumption and extra-pulmonary TB, education level, monthly income, occupation, family history of PTB, lack of appetite, balanced diet, maintaining healthy nutrition, smoking, and stopping taking medication if you felt the condition was under control and the incidence of PTB were factors associated with an increase in pulmonary tuberculosis co-infection..
Potensi Ekstrak Kulit Nanas (Ananas comosus) Sebagai Antimikroba Sinaga, Herman Fransiskus; Apriliana, Ety; Septiani, Linda; Kurniati, Intanri
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1427

Abstract

Pineapple is one of the traditional plants that may be used as an alternative treatment to reduce pathogenic microbes. Its content is rich in chlorine, iodine, phenol and the enzyme bromelain which functions to stop microbial growth. This research aims to determine the potential of pineapple peel extract (Ananas comosus) as antimicrobe agents. This research uses a literature review study method, namely by using research articles obtained through a literature search process related to the potential use of pineapple peel extract on microbe from 2015 to 2025. Pineapple peel extract contains the main compounds, namely flavonoids, polyphenols, bromelain and saponins. This content causes pineapple skin extract (Ananas comosus) to have an effect on microbes.
UJI DAYA HAMBAT EKSTRAK DAUN LIDAH MERTUA (Sansevieria trifasciata laurentii) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus Saputra, Kurnia Hadi; Apriliana, Ety; Rodiani, Rodiani; Oktarlina, Rasmi Zakiah
Medula Vol 15 No 2 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i2.1579

Abstract

Infectious and communicable diseases remain one of the leading causes of mortality in Indonesia and worldwide. Several pathogenic bacteria can cause infections, one of which is Staphylococcus aureus. This bacterium can lead to a variety of conditions, including mastitis, dermatitis (skin inflammation), respiratory tract infections, impetigo, abscesses, toxic shock syndrome, and food poisoning. With the advent of antibiotics, an increasing number of bacterial strains have developed antibiotic resistance. The primary cause of this resistance is the widespread and irrational use of antibiotics, which allows some bacteria to survive and become resistant. The snake plant (Sansevieria trifasciata laurentii) contains compounds with antibacterial properties, such as tannins, saponins, and flavonoids. This study aimed to investigate the antibacterial activity of snake plant extract against Staphylococcus aureus. The research design used was a laboratory-based observational study. The antibacterial activity of the snake plant leaf extract was tested at concentrations of 20%, 40%, 60%, 80%, and 100% against Staphylococcus aureus using the dilution method to determine the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC). The results showed that the snake plant extract exhibited antibacterial activity against Staphylococcus aureus at all tested concentrations (20% to 100%). The MIC was observed at a concentration of 20%, while the MBC was found at 40%. These findings confirm that the extract of Sansevieria trifasciata laurentii has inhibitory effects on the growth of Staphylococcus aureus.
Uji Daya Hambat Ekstrak Andaliman (Zanthoxylum Acanthopodium) terhadap Pertumbuhan Escherichia Coli Silitonga, Yona Arisena Magdalena; Apriliana, Ety; Anggraini, Dwi Indria
Jurnal Penelitian Perawat Profesional Vol 6 No 4 (2024): Agustus 2024, Jurnal Penelitian Perawat Profesional
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jppp.v6i4.2703

Abstract

Penyakit infeksi merupakan salah satu penyakit yang banyak menyebabkan kematian di seluruh dunia, terutama pada negara berkembang yang banyak mempunyai angka kematian yang tinggi, termasuk Indonesia. Escherichia coli merupakan bakteri yang normalnya hidup di dalam usus manusia dan hewan. Kebanyakan Escherichia coli tidak berbahaya, tetapi beberapa Escherichia coli merupakan patogen, yang mana dapat menyebabkan penyakit, diare atau penyakit di luar saluran usus. Infeksi oleh Escherichia coli adalah penyebab diare terbanyak kedua setelah rotavirus. Resistensi bakteri terhadap antibiotik telah menjadi masalah serius dalam kesehatan masyarakat. Derivat tanaman antibakteri selalu menjadi terapi baru. Terdapat adanya aktivitas antimikroba dari minyak atsiri andaliman (Zanthoxylum acanthopodium) serta komponen aktif penyusunnya. Penelitian ini bertujuan untuk mengetahui hasil daya hambat ekstrak buah andaliman dibandingkan kontrol positif serta menentukan diameter zona hambat ekstrak buah andaliman (Zanthoxylum acanthopodium) terhadap Escherichia coli. Desain penelitian ini adalah penelitian eksperimental murni, dengan rancangan post-test control group. Penelitian ini menggunakan bakteri Escherichia coli yang diberikan ekstrak buah andaliman dengan 6 kelompok. Konsentrasi 25% (K1), konsentrasi 50% (K2), konsentrasi 75% (K3), konsentrasi 100% (K4), kontrol negatif dengan akuades (K5), dan kontrol positif dengan gentamicin (K6), kemudian dilihat daya hambatnya dengan mengukur diameter zona hambat dengan metode difusi sumuran. Hasil rerata diameter zona hambat yaitu K1 0 mm, K2 0 mm, K3 0 mm, K4 7,25 mm, K5 0 mm, dan K6 30 mm. Hasil analisis menunjukkan p: 0,000. Analisis dilanjutkan dengan uji post hoc dan ditemukan kelompok yang memiliki perbedaan bermakna yaitu K1, K2, K3, K4 dengan K6. Efek antibakteri ekstrak buah andaliman (Zanthoxylum acanthopodium) terhadap Escherichia coli kurang signifikan.
Edukasi dan Sosialisasi Pencegahan Stunting Melalui Gerakan Gemar Konsumsi Telur Bersama Orang Tua dan Siswa PAUD Anggrek Putih Bandar Lampung Septinova, Dian; Hartono, Madi; Apriliana, Ety; Selawati, Diyah; Hermawan, Alan; Legowo, Ahmad Bambang; Agustin, Nur Aini; Nugraha, Ega; Rito, Hardiansyah Faisal
Jurnal Pengabdian Fakultas Pertanian Universitas Lampung Vol. 2 No. 2 (2023): Jurnal Pengabdian Fakultas Pertanian Universitas Lampung Vol 2 No 2, September
Publisher : Agriculture Faculty, Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpfp.v2i2.7874

Abstract

Angka stunting di Bandar Lampung pada 2022 sudah di bawah 20%.  Namun, angka tersebut masih di bawah target pemerintah Kota Bandar Lampung, yaitu maksimal 14% pada 2024.  Kegiatan pengabdian ini bertujuan membantu pemerintah Bandar Lampung untuk menurunkan kasus stunting dengan (1) meningkatkan pengetahuan dan kesadaran  wali murid Pendidikan Anak Usia Dini (PAUD) Anggrek Putih tentang stunting dan pencegahannya; (2) pengetahuan tentang teknik pengolahan dan penyajian telur; (3) menanamkam kebiasaan dan gemar mengonsumsi telur setiap hari pada anak-anak usia dini.  Pengabdian dilakukan dengan menggunakan metode (1)  penyuluhan dan diskusi pada orang tua murid, (2)  kampanye gemar makan telur pada siswa PAUD, dan (3) Evaluasi.  Kegiatan pengabdian diikuti oleh 41 wali murid dan 50 siswa PAUD. Seluruh materi kegiatan disampaikan dengan baik oleh narasumber dan disimak serta diikuti dengan sangat antusias oleh wali murid dan siswa PAUD.  Pihak sekolah PAUD Anggrek Putih menyambut baik kegiatan ini dan berharap akan ada kelanjutan dari kegiatan ini. 
Faktor-faktor yang Berhubungan dengan Kejadian Carpal Tunnel Syndrome (CTS) pada Pekerja Pembuat Cobek Putra, Muhammad Ferdiansyah; Mayasari, Diana; Apriliana, Ety
Jurnal Penelitian Perawat Profesional Vol 6 No 3 (2024): Juni 2024, Jurnal Penelitian Perawat Profesional
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jppp.v6i3.2429

Abstract

Prevalensi kejadian CTS pada penduduk umum diperkirakan 5% pada wanita dan 0,6% pada laki-laki. Pekerja pembuat cobek merupakan pekerjaan dengan risiko CTS. Penelitian ini bertujuan mengetahui faktor-faktor yang berhubungan dengan kejadian CTS pada pekerja pembuat cobek di Desa Jojog Kabupaten Lampung Timur. : Penelitian analitik observasional dengan pendekatan cross sectional. Responden terdiri dari 86 pekerja pembuat cobek dengan teknik total sampling. Penelitian ini menggunakan data primer berupa kuesioner. Analisis yang digunakan adalah chi-square. Hasil penelitian menunjukkan mayoritas responden berusia ≥40 tahun (72,10%), berjenis kelamin laki-laki (70,90%), berstatus gizi normal (68,60%), durasi kerja ≥8 jam (68,60%), masa kerja ≥4 tahun (76,70%), postur kerja pergelangan tangan level risiko tinggi (64,00%), paparan getaran (73,25%), gerakan berulang (74,41%) dan mengalami kejadian CTS (76,70%). Terdapat hubungan antara usia (p = 0,0001), durasi kerja (p = 0,002), masa kerja (p = 0,0001), postur pergelangan tangan (0,0001), paparan getaran (0,007), gerakan berulang (0,001) dengan kejadian CTS, sedangkan jenis kelamin (0,073) dan status gizi (0,692) tidak berhubungan dengan kejadian CTS. Terdapat hubungan antara usia, durasi kerja, masa kerja. postur kerja pergelangan tangan, paparan getaran dan gerakan berulang dengan kejadian CTS pada pekerja pembuat cobek di Desa Jojog Kabupaten Lampung Timur.
Penatalaksanaan secara Komprehensif Pasien Laki-Laki Usia 20 Tahun dengan Skizofrenia melalui Pendekatan Kedokteran Keluarga Saputra, Wahyu Agung Dwi; Apriliana, Ety; Jausal, Anisa Nuraisa
Jurnal Penelitian Perawat Profesional Vol 6 No 3 (2024): Juni 2024, Jurnal Penelitian Perawat Profesional
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jppp.v6i3.2593

Abstract

Skizofrenia termasuk dalam empat besar masalah kesehatan yang dihadapi dunia saat ini. Hal ini sesuai dengan data Organisasi Kesehatan Dunia (WHO) yang memperkirakan 280 juta orang menderita depresi, 301 juta orang menderita gangguan kecemasan, 40 juta orang menderita penyakit bipolar, dan 24 juta orang menderita skizofrenia. Tujuan penelitian ini untuk menerapkan pelayanan kedokteran keluarga berdasarkan evidence based medicine pada pasien dengan mengidentifikasi faktor risiko, masalah klinis, serta tatalaksana pasien berdasarkan kerangka penyelesaian masalah dengan patient centered, family approach dan community oriented. Studi yang dilakukan adalah sebuah laporan kasus. Kunjungan rumah, pemeriksaan status mental, dan autoanamnesis dan alloanamnesis digunakan untuk mengumpulkan data primer. Data sekunder didapat dari rekam medis pasien. Diagnostik holistik pertama, prosedur, dan kesimpulan kunjungan menjadi dasar penilaian. Hasil penelitian ini yaitu berupa intervensi dengan menggunakan media poster dan mengajak pasien bersosialisasi. Pemahaman yang lebih mendalam tentang penyakit dan perubahan perilaku yang mempengaruhi kemanjuran pengobatan adalah salah satu hasil yang dicapai. Kesimpulan penelitian ini adalah pengobatan keluarga telah digunakan untuk mendiagnosis dan merawat pasien dengan cara patient centered,family approach, dan community oriented.
EDUKASI TENTANG RISIKO INFEKSI PARASIT USUS PADA PERILAKU OPEN DEFECATION SEBAGAI UPAYA MENINGKATKAN PENCAPAIAN OPEN DEFECATION FREE YANG MENUNJANG PENINGKATAN DERAJAT KESEHATAN ANAK INDONESIA Mutiara, Hanna; Lisiswanti, Rika; Ramadhian, Muhammad Ricky; Islami, Suryadi; Apriliana, Ety; Fatriyadi, Jhons
BESIRU : Jurnal Pengabdian Masyarakat Vol. 1 No. 2 (2024): BESIRU : Jurnal Pengabdian Masyarakat, Februari 2024
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/480vf954

Abstract

Sustainable Development Goals (SDGs) have set 17 development goals that must be achieved by 2030. One of the goals is to ensure a healthy and prosperous life for all communities. This health-related component is related to access to clean water and sanitation to create a healthy environment and will reduce the risk of transmission of various infectious diseases, especially diarrhea. Diarrhea is currently one of the biggest killers of toddlers in Indonesia. This disease is an environmental-based disease that is closely related to the practice of open defecation. Diarrhea can be caused by several etiologies, including intestinal parasitic diseases.  One of the targets set out in the SDGs related to healthy sanitation is access to achieving stop open defecation behavior. Stichting Nederlandse Vrijwilligers (SNV) in April 2022 stated that of the 9 million residents in Lampung, around 1 million people do not have access to a toilet or still practice open defecation. Of the 15 city districts in Lampung Province, only five regions have implemented ODF. The aim of this activity is to make an effort to improve children's health status, in particular increasing knowledge about the risk of intestinal parasite infection in open defecation behavior. This is expected to increase motivation and practice to stop open defecation so that it can increase the achievement of open defecation free in Indonesia, especially Lampung Province. It is hoped that this will improve the level of health, especially for Indonesian children who are the nation's next generation.
Faktor Risiko Personal dan Lingkungan dalam Kejadian Demam Tifoid Kurniawan, Diva Ardhana; Apriliana, Ety; Sutarto, Sutarto; Himayani, Rani
Medula Vol 14 No 11 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i11.1328

Abstract

Typhoid fever is one of the infectious diseases that has a fairly high morbidity and mortality rate, especially in developing countries, especially in Indonesia. Typhoid fever is an infectious disease caused by the bacteria Salmonella typhi. This disease can be transmitted through consuming water or food contaminated with urine and feces from typhoid fever sufferers, for example, water that will be used for drinking, cooking, or washing food ingredients. There are more serious clinical symptoms, such as high fever or hyperthermia, remittent fever, and decreased level of consciousness that can lead to coma or delirium. Further complications such as dehydration and acidosis can also occur, which have negative impacts in cases of typhoid fever. The purpose of this review article is to determine what personal and environmental risk factors are present in the occurrence of typhoid fever. The method used in this study is a review article with specific research of various articles found, then combined and a summary conclusion is drawn. The journals used have been published for the past 5 years (2019-2024). The results and conclusions show that several personal and environmental risk factors in the occurrence of typhoid fever include age, gender, personal hygiene, and clean water sources.
Manuver Epley dan Brandt-Daroff Dalam Penatalaksanaan Benign Paroxysmal Positional Vertigo (BPPV) Hafidah, Hazima Hasna; Marcellia, Selvi; Apriliana, Ety
Medula Vol 14 No 10 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i10.1383

Abstract

Benign Paroxysmal Positional Vertigo (BPPV) is the most common cause of vertigo with a case prevalence of 1.6% globally. It is characterized by recurrent episodes of vertigo due to changes in head position. BPPV disease is caused by the transfer of otoconia to the semicircular canal, stimulating the vestibulocochlear nerve resulting in symptoms of vertigo, nystagmus, and becoming more sensitive to head movement. The impact is significant on the physical, psychological, and quality of life aspects of the patient. This literature review discusses the mechanism, effectiveness, and success rate of Epley and Brandt-Daroff maneuvers. Data were obtained from relevant literature with data sources coming from Pubmed, NCBI, and Google Scholar.  The results of the literature review showed that the Epley maneuver has high effectiveness with a cure rate of up to 92% within one week and a significant reduction in sequelae, especially in the modified Epley maneuver. In addition, the Brandt-Daroff maneuver proved to be effective for self-treatment at home with gradual improvement of vertigo symptoms. Both methods have advantages, such as the flexibility of the Brandt-Daroff maneuver and quick results in the Epley maneuver, but have certain limitations in patients with comorbid conditions. The conclusion of this literature review shows that the Epley maneuver is the first choice in the treatment of BPPV due to its higher effectiveness, while the Brandt-Daroff maneuver can be used as an alternative.
Co-Authors Adisti, Fransiska Afifah, Syafira Hasna Agustin, Nur Aini Ahmadi, Peni Alvinasyrah, Alvinasyrah Alvista, Valentina Nancy Ambarwati, Yuli Andi Setiawan Arafah, Aisyah Putri Arai, Masayoshi Ari Wahyuni Aspita Laila Bayu Anggileo Pramesona Betta Kurniawan, Betta Carolia, Imelda Dian Isti Angraini Dian Septinova Dwi Indria Anggraini Dyah Wulan Sumekar Rengganis Wardani Efrida Warganegara Efriyan Imantika Fitria Saftarina Frauprades, Kaltihennah Oktavia Giska Tri Putri Hafidah, Hazima Hasna Hanna Mutiara, Hanna Helmi Ismunandar Hendra Tarigan Sibero Hermawan, Alan Ildha Rosendy Kurnianda Indri Windarti Intanri Kurniati Irawati, Nur Ayu Virginia Islamy, Suryadi Janar Wulan, Anggraini Jausal, Anisa Nuraisa Jhons Fatriyadi Suwandi John Hendri Juliasih, Ni Luh Gede Ratna Karima, Nisa Kartika, Juspeni Khairun Nisa Kurniawan, Diva Ardhana Kurniawaty, Evi Legowo, Ahmad Bambang Madi Hartono Marcellia, Selvi Mayasari, Diana Muatiara, Hanna Muhammad Aditya, Muhammad Muhammad Ricky Ramadhian Muhammad Yusran Novi Nurhayati, Novi Novita Carolia Nugraha, Ega Nurul Utami Oktafany, Oktafany Oktaryona Trisera Puspita, Ratna Dewi Putra, Muhammad Ferdiansyah Qonita, Adzrok Rahel, Clara Arta Uli Rahmadian, M. Ricky Ramadhana Komala Rani Himayani Rasmi Zakiah Oktarlina Ratna Dewi Puspita Sari Ratna, Maya Ganda Reni Zuraida Rika Lisiswanti Rito, Hardiansyah Faisal Rodiani, Rodiani Sabila, Ghina Salsabila, Nafila Khansa Saputra, Kurnia Hadi Saputra, Wahyu Agung Dwi Sari, Merry Indah Selawati, Diyah Septia Eva Lusina Septiani, Linda Setiawan, Gigih Shinta Dewi, Brigitta Shinta Nareswari, Shinta Sihaloho, San Maulina Silitonga, Yona Arisena Magdalena Sinaga, Herman Fransiskus Sofyan Musyabiq Wijaya Suharmanto Suryadi Islami Susianti, Susianti Sutarto Sutarto Suwandi, Jhosn Fatriyadi SYAIFUL BAHRI Tengku Riza Zarzani N Tri Umiana Soleha Tugiyono Tugiyono Utari Gita Mutiara WAWAN ABDULLAH SETIAWAN, WAWAN ABDULLAH Widyastuti Widyastuti Yusran, M