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Helmi Arifin
Universitas Andalas
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Indonesian Journal of Multidisciplinary Science

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Analyzing ACEI-Furosemide and ARB-Furosemide Drugs Combination on Hypertension and Chronic Kidney Disease Patients Hesti Effendi; Helmi Arifin; Nasrul Zubir
Indonesian Journal of Multidisciplinary Science Vol. 2 No. 4 (2023): Indonesian Journal of Multidisciplinary Science
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (890.82 KB) | DOI: 10.55324/ijoms.v2i4.407

Abstract

The purpose of this study was to compare the efficacy of ACE-inhibitor + Furosemide and ARB + Furosemide in lowering creatinine, urea, and blood pressure in individuals with hypertension and chronic renal disease. This is a retrospective study in which data were extracted from the medical records of patients with hypertension and chronic kidney disease in the Internal Medicine Ward of the General Hospital dr. M. Jamil Padang in West Sumatera. A 2-by-3 ANOVA hypothesis test design was utilized. The hypothesis was evaluated using an alpha value of 0.05. The results demonstrated that the ARB + Furosemide combination was superior to the ACE-Inhibitor + Furosemide combination by 86.2%. In addition, this study demonstrated that the medication combinations ACE inhibitor plus furosemide and ARB plus furosemide were equally efficient in lowering creatinine, urea, and blood pressure in individuals with hypertension and chronic renal disease. The researchers found that antihypertensive medicines, including the ACE-Inhibitor + Furosemide combination and the ARB + Furosemide combination, can be administered at levels determined by the patient's clinical situation. Also, while selecting a pharmacological combination between an ACE inhibitor and furosemide or an ARB and furosemide, it is important to consider the adverse effects of the drugs. For instance, it is preferable to combine ARB with Furosemide.
Co-Authors -, Risfaheri ., Nirwanto Agustini, Tiara Tri Akmal M. Hanif Almahdy Almahdy Ariadi, Aried Aried Ariadi Aried Eriadi Arina Widya Murni Asram Ahmad Barmitoni Barmitoni Benny Benny Bobbi Hemriyantton Candra Syuryani Dahlyanti, Rina Delladari Mayefis Deni Kurniati Deswinar Darwin Dewi Eka Putri Dian Ayu Juwita Diana Idrifa Dwisari Dillasamola Eddy Duarto Elisma Elisma Elisma Elisma Elka Elka Ella Handalia Endang Purwati RN Erlina Rustam Fajrian Aulia Putra Fathul Jannah Feni Efrianti Fitri Maya Sari Gina Sonia Harto H. Havizur Rahman Havizur Rahman Hengki Afdhal Henny Lucida Heppy Riyono Hesti Effendi Hidayat, Zoni Hidayati Hidayati Hilmarni Hilmarni Ifora Ifora Ira Oktaviani Rz Jaka Perdana Leli Sriyani Machdawaty Masri Masitah Masitah Menkher Manjas Meri Andani Meri Susilawati Merry C, Ann Murni, Yulia Nasrul Zubir Nela Andriani Nelfa Yulianti Nelwati, Nelwati Netty Suharti Nirwanto . Nirwanto Nirwanto Nofiza, Welli Novi Priyoka Putra Novika Maulina Octy Aisyahharma Rahimatul Uthia Rahimatul Uthia Rahman, Havizur Rahmi Yosmar Rahmi Yulia Nesia Randika Fransiska Raveinal Raveinal Raveinal Raveinal RAVEINAL RAVEINAL Rella Silvia Reni Trevia Ria Irawati Rina Dahlyanti Ririn Anjelin Risfaheri - Rizky Yulion Rosa Julia Wijaya Rostin Rostin Rusdi Rusdi Rusdi Saputra, Harry Saputra, Harry Satrina Chania Sinata, Novia Solly Aryza Sri Ana Setianingsih Sri Oktavia Sri Oktavia Suci Ahda Novitri Suhatri Suhatri Sumanti, Titi Sumaryati Syukur Surya Dharma Susi Handayani Tesa Inmerka Alwi Titi Sumanti Vivi Resviana Wesnawati, Wesnawati Widya Kardela Wildra Martoni Yulia Murni Yuliana Arsil Yuni Andriani Zet Rizal Zet Rizal ZK Abdurahman Baizal Zoni Hidayat