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All Journal JURNAL KIMIA SAINS DAN APLIKASI Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Jurnal Kimia Riset Majalah Kedokteran Sriwijaya JPSriwijaya Biomedical Journal of Indonesia Jurnal Kesehatan Alami Journal (Alauddin Islamic Medical) Journal SRIWIJAYA JOURNAL OF MEDICINE Molekul: Jurnal Ilmiah Kimia Bioscientia Medicina : Journal of Biomedicine and Translational Research Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) World Nutrition Journal Jurnal Triton Jurnal Pengabdian Masyarakat: Humanity and Medicine Bioscientia Medicina : Journal of Biomedicine and Translational Research Conferences of Medical Sciences Dies Natalis Joong-Ki Joong-Ki
Susilawati Susilawati
2Faculty Of Medicine, Sriwijaya University, Palembang, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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UJI POTENSI ANTIPLASMODIUM EKSTRAK BUAH PARE (Momordica charantia L.) TERHADAP Plasmodium falcifarum Susilawati Susilawati; Hermansyah Hermansyah
Molekul Vol 9, No 1 (2014)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (170.755 KB) | DOI: 10.20884/1.jm.2014.9.1.145

Abstract

Malaria masih menjadi salah satu penyakit endemis dan masalah kesehatan utama di Indonesia.  Buah pare (Momordica charantia L.) secara tradisional sering digunakan sebagai obat.   Tujuan dari penelitian ini adalah untuk menguji potensi antiplasmodium in vitro ekstrak buah pare terhadap Palsmodium falciparum sehingga dapat digunakan sebagai obat anti malaria.   Buah pare diekstrak dengan metode maserasi menggunakan pelarut metanol.  Uji aktivitas antiplasmodium dilakukan secara pengamatan mikroskopik pada kultur strain P. falcifarum  3D7. Berdasarkan hasil pengujian, sampel ekstrak metanol buah pare memiliki aktivitas penghambatan terhadap pertumbuhan parasit P. falciparum 3D7. Kekuatan aktivitas antimalaria dengan nilai IC50 = 0,39 µg/mL.
AKTIVITAS LARVASIDA EKSTRAK METANOL BUAH PARE (Momordica charantia L.) TERHADAP LARVA Aedes aegypti Susilawati Susilawati; Hermansyah Hermansyah
Molekul Vol 10, No 1 (2015)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (395.661 KB) | DOI: 10.20884/1.jm.2015.10.1.171

Abstract

Demam berdarah masih menjadi salah satu penyakit endemis dan masalah kesehatan utama di Indonesia. Buah pare(Momordica charantia L.) secara tradisional sering digunakan sebagai obat. Tujuan dari penelitian ini adalah untuk mengetahui efektifitas larvasida ekstrak metanol buah pare (Momordica charantia L.) terhadap larva Aedes aegypti dan mengetahui nilai LC50.  Buah pare diekstrak dengan metode maserasi menggunakan pelarut metanol. Uji efektifitas larvasida dilakukan dengan menghitung jumlah larva uji yang mati setelah terpapar ekstrak buah pare dalam waktu tertentu. Berdasarkan hasil pengujian, sampel ekstrak metanol buah pare memiliki aktivitas larvasida terhadap larvaAedes aegypti. Nilai LC50 ekstrak metanol buah pare untuk tiap waktu pajanan berbeda.
Contamination of Soil Transmitted Helminths (STH) Eggs in Raw Vegetables at Street Food Stalls and Restaurant in Lorok Pakjo Village, Palembang Leo Medianto Faziqin; Dalilah; Dwi Handayani; Chairil Anwar; Susilawati
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 6 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i6.397

Abstract

Background: Infection Soil Transmitted Helminths (STH) is a disease that is a problem in the world, especially in areas with a tropical climate like Indonesia. This infection can be transmitted through consumption of raw vegetables contaminated with STH. This study aims to determine whether there is contamination of STH eggs in raw vegetables at street food stalls and restaurants in Lorok Pakjo Village, Palembang. Methods: This research is a descriptive observational study. Samples in the form of fresh vegetables were collected from 18 street stalls and 14 restaurants in Lorok Pakjo Village, Palembang. Samples were examined using the sedimentation method and observed using a microscope. Results: The results obtained 80 samples consisting of 30 cabbage, 18 basil, 30 cucumber, 1 lettuce, and 1 eggplant. Of the 80 samples, there were 20 (25%) positive samples contaminated with STH eggs consisting of 8 (10%) cabbage samples, 8 (10%) basil samples, 4 (5%) cucumber samples, and no STH contamination was found in lettuce. and eggplant. Of the 20 positive samples of STH contamination, 12 samples came from street vendors consisting of 5 (10.6%) cabbage samples, 6 (12.8%) basil samples, and 1 (2.1%) cucumber samples. While the other 8 samples came from restaurants consisting of 3 (9.1%) cabbage samples, 2 (6%) basil samples, and 3 (9.1%) cucumber samples. Found only eggs of Ascaris lumbricoides infertile decorticate in all samples consisting of 9 eggs on cabbage, 16 eggs on basil, and five eggs on cucumber. Conclusion: There is contamination of eggs Soil Transmitted Helminths in raw vegetables in street food stalls and restaurants in Lorok Pakjo Village, Palembang.
Gene Expression Changes and Anti-proliferative Effect of Noni (Morinda Citrifolia) Fruit Extract Analysed by Real Time-PCR Hermansyah Hermansyah; Susilawati Susilawati
Molekul Vol 12, No 1 (2017)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (674.733 KB) | DOI: 10.20884/1.jm.2017.12.1.333

Abstract

To elucidate the anti-proliferative effect of noni (Morinda citrifolia) fruit extract for a Saccharomyces cerevisiae model organism, analysis of gene expression changes related to cell cycle associated with inhibition effect of noni fruit extract was carried out. Anti-proliferative of noni fruit extract was analyzed using gene expression changes of Saccharomyces cerevisiae (strains FY833 and BY4741).  Transcriptional analysis of genes that play a role in cell cycle was conducted by growing cells on YPDAde broth medium containing 1% (w/v) noni fruit extract, and then subjected using quantitative real-time polymerase chain reaction (RT-PCR).  Transcriptional level of genes CDC6 (Cell Division Cycle-6), CDC20 (Cell Division Cycle-20), FAR1 (Factor ARrest-1), FUS3 (FUSsion-3), SIC1 (Substrate/Subunit Inhibitor of Cyclin-dependent protein kinase-1), WHI5 (WHIskey-5), YOX1 (Yeast homeobOX-1) and YHP1 (Yeast Homeo-Protein-1) increased, oppositely genes expression of DBF4 (DumbBell Forming), MCM1 (Mini Chromosome Maintenance-1) and TAH11 (Topo-A Hypersensitive-11) decreased, while the expression level of genes CDC7 (Cell Division Cycle-7), MBP1 (MIul-box Binding Protein-1) and SWI6 (SWItching deficient-6) relatively unchanged. These results indicated that gene expression changes might associate with anti-proliferative effect from noni fruit extract. These gene expressions changes lead to the growth inhibition of S.cerevisiae cell because of cell cycle defect.
DOMINO CLINICAL CARDS TRAINING TO IMPROVE LECTURERS' ABILITIES IN CLINICAL REASONING LEARNING MEDIA Irfannuddin Irfannuddin; Eka Febri Zulissetiana; Susilawati Susilawati; Mailan Alexander
Conferences of Medical Sciences Dies Natalis Vol. 3 No. 1 (2021): Conference of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sri
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (425.391 KB)

Abstract

Medical practitioners sometimes perform inappropriate decisions and procedures. In making decisions, doctors may take a poor thinking called cognitive and representative bias.One matrix approach that can be developed to build learners' clinical reasoning is the domino game method. Domino card games (DCC) are a form of visual learning that can increase student learning motivation. DCC media is carried out in the form of competitive games. However, DCC is part of collaborative and peer learning methods. Collaborative learning is a method in which learners collaborate with each other. This method is considered to increase learning motivation. Collaboration makes them understand their learning process. The process of collaboration makes them internalize knowledge with critical thinking skills. Peer learning is the learning activity of a group of students from a similar social group. Peer learning activities can be in peer tutoring, peer assessment, or game and simulation forms. Peer learning tutoring can improve the quality of learning efficiently.DCC is an alternative instrument that can be developed to improve clinical reasoning skills. Through this training, some lecturers have been able to compile and develop DCC prototypes. Furthermore, they can apply according to their respective fields of knowledge.
Sungkai Leaf Potential as Herbal Medicine Sadakata Sinulingga; Fatmawati Fatmawati; Subandrate Subandrate; Irfannudin Irfannudin; Susilawati Susilawati; Rini Yana
Conferences of Medical Sciences Dies Natalis Vol. 3 No. 1 (2021): Conference of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sri
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (291.582 KB)

Abstract

Indonesia is a tropical country that has biodiversity. One of the biodiversity in Indonesia is the availability of many medicinal plants. The Indonesian Ministry of Health has released a formulary of Indonesian medicinal plants in 2017. One of the plants that has medicinal properties is the sungkai plant. Sungkai plants grow in most parts of Indonesia, including South Sumatra. This plant is also often planted in the yard as a shade. Empirically, sungkai leaves have been used as medicine by various tribes in Indonesia. People use boiled water from sungkai leaves or crushed sungkai leaves as herbal medicine. The phytochemical content of sungkai leaves includes alkaloids, flavonoids, triterpenoids, steroids, phenols and saponins. The results of various studies show that sungkai leaves have benefits as anti-fever, antimalarial, antibacterial and antioxidant. Sungkai leaves also have the ability to increase endurance, so they can be used to fight infectious diseases including Covid19. Sungkai leaves can be used for herbal medicine either as a preventive or therapeutic agents. Further development for the use of Sungkai plants as medicine needs to be done to assess side effects and therapeutic effects more efficiently.
Hubungan Laju Filtrasi Glomerulus dengan Derajat Anemia pada Penderita Penyakit Ginjal Kronik Dian Natalia; Susilawati; Safyudin
Sriwijaya Journal of Medicine Vol. 2 No. 3 (2019): Vol 2, No 3, 2019
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v2i3.52

Abstract

Penyakit ginjal kronik (PGK) adalah proses patologis yang mengakibatkan penurunan progresif fungsi ginjal yang ditandai dengan penurunan laju filtrasi glomerulus. Penyakit ginjal kronik dapat mengakibatkan terjadinya anemia dan osteodistrofi renal. Anemia merupakan komplikasi penyakit ginjal kronik yang paling sering terjadi. Penelitian ini dilakukan untuk mengetahui hubungan laju filtrasi glomerulus dengan derajat anemia penderita PGK di RSUP Dr. Mohammad Hoesin Palembang. Penelitian ini merupakan penelitian analitik observasional dengan pendekatan cross sectional. Sampel penelitian ini adalah pasien yang didiagnosis penyakit ginjal kronik di RSUP Dr. Mohammad Hoesin Palembang dan tercatat di rekam medik tahun 2017 yang memenuhi kriteria inklusi dan eksklusi. Dari 214 pasien, didapatkan 55,1% penderita PGK adalah laki-laki dan 35% berumur 50-59 tahun. Berdasarkan derajat PGK didapatkan 79,4% penderita PGK memiliki derajat 5 dan berdasarkan derajat anemia didapatkan 94,9% penderita PGK mengalami anemia derajat sedang dan berat. Nilai cutoff LFG dan kadar Hb pada seluruh sampel didapatkan nilai < 8,56 mL/min/1,73m2, pada laki-laki < 8,1 mL/min/1,73m2, dan pada perempuan < 9,43mL/min/1,73m2. Hasil analisis menggunakan uji Chi-square menunjukkan bahwa LFG memiliki hubungan yang signifikan dengan derajat anemia (p=0,000). Terdapat hubungan yang signifikan antara laju filtrasi glomerulus dan derajat anemia pada penderita penyakit ginjal kronik di RSUP Dr. Mohammad Hoesin Palembang maka laju filtrasi glomerulus merupakan faktor risiko dari derajat anemia.
Hubungan Akreditasi Sekolah, Asal Sekolah, Jalur Penerimaan Mahasiswa dan Tempat Tinggal dengan Indeks Prestasi Kumulatif Mahasiswa M.Rizki Alkautsar; Susilawati; Mutiara Budi Azhar
Biomedical Journal of Indonesia Vol. 4 No. 3 (2018): Vol 4, No 3, 2018
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Proses pembelajaran merupakan kegiatan utama dalam dunia pendidikan, termasuk di Perguruan Tinggi (PT). Keberhasilan proses pembelajaran dipengaruhi oleh faktor internal dan faktor eksternal. Untuk mengukur keberhasilan dalam pembelajaran di universitas menggunakan Indeks Prestasi Kumulatif. Tujuan objektif dari penelitian ini adalah menentukan hubungan akreditasi sekolah, asal sekolah, jalur penerimaan, dan tempat tinggal dengan IPK mahasiswa PSPD angkatan 2014 FK Unsri. Jenis penelitian ini adalah observasi analitik dengan desain potong lintang. Responden dalam penelitian ini adalah seluruh mahasiswa PSPD Angkatan 2014 FK Unsri yang memenuhi kriteria inklusi sebanyak 216 mahasiswa. Data diambil dari Sub-bagian Akademik berupa data IPK dan jalur penerimaan dan Unit Bimbingan Konseling Mahasiswa (UBKM) berupa data asal sekolah dan tempat tinggal sedangkan data akreditasi sekolah diperoleh dari web resmi Kementrian Pendidikan dan Kebudayaan. Analisis data bivariat menggunakan uji Chi-Square bila memenuhi syarat. Bila tidak memenuhi syarat maka digunakan uji alternatif yaitu kolmogorov-smirnov. Berdasarkan analisis bivariat, tidak terdapat hubungan akreditasi sekolah (A dan B) dan asal sekolah (kota dan kabupaten) dengan IPK dengan nilai p= 1,000, tidak terdapat hubungan asal sekolah (Palembang dan luar Palembang) dengan IPK dengan nilai p= 0,843, dan tidak terdapat hubungan tempat tinggal (bersama orang tua dan kos) dengan IPK dengan nilai p=0,730 sedangkan berdasarkan analisis bivariat terdapat hubungan jalur penerimaan (SNMPTN, SBMPTN, dan USM) dengan IPK dengan nilai p= 0,000. Terdapat hubungan jalur penerimaan dengan IPK Mahasiswa PSPD Angkatan 2014 FK Unsri.Namun, tidak terdapat hubungan akreditasi sekolah, asal sekolah dan tempat tinggal dengan IPK Mahasiswa PSPD Angkatan 2014 FK Unsri.
Pendampingan deteksi mandiri sindrom metabolik melalui pemeriksaan IMT, obesitas sentral, tekanan darah, dan pemeriksaan kadar kolesterol Susilawati Susilawati; Puji Rizki Suryani; Rara Inggarsih; Masayu Farah Diba; Septi Purnamasari
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 1 No 3 (2020): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V1I3.4

Abstract

The shift in eating patterns generally in urban communities where the composition of food consumed tends to be higher in fat and low in fiber. Bad sleep quality due to heavy work, is also a risk factor for various health problems such as hypertension, obesity, insulin resistance and dyslipidemia; we call it metabolic syndrome. Many studies have shown that the number of morbidity and mortality due to metabolic syndrome increases significantly. Community service activities in the form of counseling about raising public awareness about metabolic syndrome, especially people in the village of Talang Petai. Aim of this activity is to increase awareness to carry out prevention and health care activities through dietary arrangements, sleep patterns, increasing physical activity, and immediately check into a health service if there are signs and symptoms of disease. The results of this activity, there is an increase in public knowledge about the dangers and how to promote and prevent metabolic syndrome. Henceforth, it needs to be done continuous community service activities so that health status can be increased.
Upaya peningkatan kesadaran preventif terhadap diabetes mellitus pada generasi milenial Riana Sari Puspita Rasyid; Susilawati; Arwan Bin Laeto; Rara Inggarsih; Masayu Farah Diba
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 1 No 2 (2020): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V1I2.5

Abstract

Efforts to increase preventive awareness of non-communicable diseases in millenials. Diabetes mellitus is a non-communicable disease that causes metabolic disorders. The etiology of diabetes mellitus is including heredity, viruses that cause pancreatic beta cell damage, diet, obesity, activity patterns, environment and sleep habits. Community service activities aim to increase adolescent knowledge of the prevention of non- communicable diseases, especially diabetes mellitus. Activities carried out in the form of counseling about the signs and symptoms of general symptoms and risk factors for non-communicable diseases and its complications, independent analysis of sleep quality, body mass index), measurement of upper arm circumference and analysis of blood glucose levels. The results of this activity obtained an increase in adolescent insight about non-communicable diseases (especially diabetes mellitus) and increase knowledge about promotive and preventive from this diseases. Continuous service activities are needed to be carried out to the adolescents so that public health can improve.
Co-Authors Alfian Hasbi Annisa Amelia Anwar, Chairil Ardesy Melizah Kurniati Ardesy Melizah Kurniati Arwan Bin Laeto Chairil Anwar Dalilah Dalilah Dalilah Dasril Basir Dian Dwita Maizur Dian Natalia Dwi Handayani Dwi Handayani Dzakiyah Dzakiyah Eka Febri Zulissetiana Eliza Syafni Eny Rahmawati Fahira Anindita Fatmawati Fatmawati Fatmawati Febriana Ayu Shavira Geo Vanda Geo Vanda Gita Dwi Prasasty Gita Dwi Prasasty Gita Dwi Prasasty Hamzah Hasyim Heni Yohandini Hermansyah Hermansyah Hermansyah Herwin Purnomo Husna Syafira Muthmainnah Irfannuddin Irfannuddin Irfannudin Irfannudin Irfannudin Irfannudin Jefri Liasta Leo Medianto Faziqin Liniyati D Oswari M.Rizki Alkautsar Mailan Alexander Marieska Verawaty Masayu Farah Diba Masayu Farah Diba Masayu Farah Diba Miksusanti Miksusanti Muhamad Umar Harun Mutiara Budi Azhar Natasha Hutagalung Opel Berlin Oswari, Liniyanti D Pramoe Wibowo Puji Rizki Suryani Puji Rizki Suryani Rahman Irpan Pahlepi Rara Inggarsih Riana Sari Puspita Riana Sari Puspita Rasyid Rina Sopiana Rini Yana Rujito Agus Suwignyo Sadakata Sinulingga Safyudin Septi Purnamasari Sisi Melansi Subandrate Sutari Sutari Syafrianto Syafrianto Syofyanengsih Syofyanengsih Titin Kusuma Tri Hari Irfani Tri Suciati Tri Suciati