Hafni Bachtiar
Bagian Ilmu Kesehatan Masyarakat Fakultas Kedokteran Universitas Andalas

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Pengaruh Pemberian Antibiotik Profilaksis Sefazolin, Seftriakson dan Antibiotik Seftriakson Sebelum dan Sesudah Operasi Terhadap Infeksi Luka Pasca Operasi Marni, Herti; Djanas, Dovy; Bachtiar, Hafni
Andalas Obstetrics And Gynecology Journal Vol 4, No 1 (2020)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.1.77-86.2020

Abstract

Objective : To determine the effect of giving prophylactic antibiotic ceftriaxone and cefazolin and giving ceftriaxone before and after surgery to the risk of postoperative wound infection in postoperative patients.Method: This study was an experimental study with a post test control group design that looked at the differences in the effect of administration of ceftriaxone, cefazolin, and ceftriaxone before and after surgery on the risk of postoperative wound infection. The population in this study were patients planned for surgery in the Obstetric and Gynelologic Departement of Dr. M. Djamil General Hopital, Padang. The number of samples used by 30 people with a group of 10 people each group. The study began in August until the number of samples was fulfilled. Univariate analysis was used to see the frequency, percentage, mean, and standard deviation. Bivariate analysis using Chi-square test with 95% CI (α <0.05) was used to see differences in the effect of the three antibiotic procedures.Results: There were no cases of postoperative wound infection based on the three procedures used. There was no difference in the effect of prophylactic antibiotics in postoperative infections. Conclusion: There was no difference in the effect of the three procedures for prophylactic antibiotics in postoperative infections.Keywords: Prophylactic Antibiotics, Surgical Wound Infections, Cefazolin, Ceftriaxone, Superficial incisional SSI
Correlation of Colony Lactobacillus spp. with The Incident of Overactive Bladder with OBSS Score at Pauh Primary Health Center Padang Gumilar, Rimbun Wahyu; Utama, Bobby Indra; Bachtiar, Hafni
Andalas Obstetrics And Gynecology Journal Vol. 5 No. 1 (2021)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.1.56-62.2021

Abstract

Background : Overactive bladder (OAB) is a group of urgent symptoms, with or without urgent incontinence. Research shows that some Lactobacillus spp. can be a sign of a women bladder’s good health; and found a decrease number of Lactobacillus spp. in patients with OAB. This study aims to assess the correlation of Lactobacillus spp. colony with OAB using the OABSS score at Pauh Primary Health Center, Padang.Method : This research is an analytic study with a cross sectional comparative design. The research was conducted from December 2019 to February 2020 at Pauh Primary Health Center. All women aged 20-40 years who came to Pauh Primary Health Center during the study period were included in the study. Pregnant women, having pelvic abnormalities and a history of other urinary tract diseases or having a history of hypertension and diabetes mellitus were excluded in the study. Numerical data are presented in the form of central tendency. Bivariate analysis was performed using the t-independent test if the data distribution was normal and the Kolmogorov-Smirnov test if the distribution of the data was not normally distributed.Result: There were 42 samples consisting of 21 OAB respondents and 21 normal respondents. The age of the respondents in the OAB group was 28 ± 6.8 years, while the normal group was 32 ± 7.3 years (p> 0.05). The number of Lactobacillus spp colonies in the normal group was higher than the OAB group, namely 16,389,670 ± 74,380,427.9 CU / ml compared to 15,229,634 ± 67,553,932.9 CU / ml (p> 0.05).Conclusion: There was no correlation between the number of Lactobacillus Spp colonies and the incidence of Overactive Bladder. It is necessary to do further research regarding other risk factors associated with the incidence of OAB and the causes of the decrease number of Lactobacillus spp colonies in OAB patients and the presence of other microorganisms, especially pathogenic microorganisms. Keywords: overactive bladder, Lactobacillus, OABSS score
Relationship between Husband's Support, Knowledge Level, and Motivation with IVA Examination Behavior in Women of Childbearing ge in Padang City Putri, Intan Firmana; Ferry, Ferdinal; Bachtiar, Hafni
Andalas Obstetrics And Gynecology Journal Vol. 5 No. 1 (2021)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.1.50-55.2021

Abstract

Background: Cancer is the second leading cause of death in the world. Cervical cancer is in the 9th position out of 35 types of cancer causing the most deaths in the world. Cervical cancer is the second highest type of cancer after breast cancer in women, which affects more than 1.4 million women worldwide. Every year more than 460,000 cervical cancer incidents occur and about 231,000 women die from the disease.Objectives: This study aims to determine the relationship between husband's support, level of knowledge and motivation, with the behavior of IVA examination in fertile aged women in the city of Padang.Methods: This research is an analytic observational study with  cross-sectional comparative study approach that looks at the relationship between knowledge, motivation, and husband's support with IVA examination behavior in women of childbearing age.Results: The percentage who did not perform IVA examination was higher among respondents with low motivation compared to those with high motivation, namely 54.7% versus 45%. Statistically this difference was not significant (p> 0.05). The number of respondents who did not perform IVA examinations was higher for respondents with less husband's support, namely 32 respondents (42.1%) and more than half of respondents who did IVA examinations, namely 44 respondents (57.9%) who received less support from their husbands. Statistically this difference was significant (p <0.05).Conclusion: There is a relationship between the level of knowledge and the behavior of the IVA examination, there is no relationship between motivation and the behavior of the IVA examination and there is a relationship between the level of knowledge and the behavior of the IVA examination.Keywords: IVA, women of childbearing age, education
Differences of Magnesium Level Between Normal Pregnancy and Preeclamsia Pradipta, Rengga; Sriyanti, Roza; Bachtiar, Hafni
Andalas Obstetrics And Gynecology Journal Vol. 5 No. 1 (2021)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.1.63-68.2021

Abstract

Background: Preeclampsia is a multi-organ disorder that occurs in pregnant women with high blood pressure which is still difficult to predict. Until now, many theories have put forward the causes of preeclampsia, one of which is much debated is the lack of nutrition in pregnant women which can lead to preeclampsia. Several studies suggest that there is a relationship with the lack of micronutrient intake, especially magnesium, which causes preeclampsia, especially in developing countries. Magnesium deficiency is one possible factor causing severe preeclampsia. Magnesium plays a role in normal neuromuscular function, regulation of calcium, potassium and transport of sodium in the membrane as a regulation of the activation of ATP. Magnesium also plays a role in blood pressure regulation. Magnesium deficiency can lead to endothelial malfunction, hypertension and failure of the cardiovascular system. The role of magnesium is in enzyme reactions that bind to anaerobic glucose metabolism, the krebs cycle, fatty acid oxidation and reactions between coenzyme and fatty acids. Magnesium deficiency will result in changes to the nerves, muscles and blood vessels.Methods: Analytical observational study with cross sectional design in 17 women with preeclampsia and 17 normal pregnant women who met the inclusion and exclusion criteria. Research subjects were collected at Dr M Djamil Padang General Hospital, November 2019 to January 2020. Magnesium levels were checked by enzymatic methods. The difference in the mean magnesium preeclampsia and normal pregnancy was analyzed using independent t test.Results: Mean magnesium in preeclampsia was lower than normal pregnancy (1.61 ± 0.59aµg / ml vs 2.20 ± 0.18, p = 0.001).Conclusion: Mean magnesium level in preeclampsia was significantly lower than normal pregnancy..Keywords: Average levels of magnesium, magnesium, preeclampsia, normal pregnancy
The Effect of Oral Albumin Intake on Serum Albumin Levels in Preeclamsia Patients With Hypoalbuminemia in RSUP Dr. M. Djamil Padang Fitriansyah, Irwin; Djanas, Dovy; Bachtiar, Hafni
Andalas Obstetrics And Gynecology Journal Vol. 5 No. 1 (2021)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.1.69-81.2021

Abstract

Introduction : Albumin main function is maintaining the plasma colloid oncotic pressure. Preeclampsia cause a decrease in serum albumin in the pregnant woman. Low albumin levels increase mortality, longer wound healing and longer hospital stays. The intake of oral albumin is expected to be effective in increasing the level of albumin in the blood.Objective : To determine the effect of freeze dryer method intake compared to liquid snakehead fish extract in patients with preeclampsia and hypoalbuminemia.Material and methods : Using pre and post-test control group design.The total sample was 38 patients with severe preeclampsia with hypoalbuminemia, divided into control and intervention groups. Control was given the intake of liquid snakehead fish extract, in the intervention was given the Freeze dryer method. The research data were analyzed using the Mann Whitney test method and the Wilcoxon test.Results : In the intervention group the mean pretest albumin level was 2.66 ± 0.17 gr / dl and on the 4th day it was 3.13 ± 0.16 gr / dl (p = 0.000). In the control group the mean pretest albumin level was 2.72 ± 0.15 gr / dl and on the 4th day it became 3.06 ± 0.14 gr / dl (p = 0.000). On the 4th day after treatment, the increase in serum albumin levels in the intervention group was 0.47 ± 0.19 gr / dl; whereas in the control group was 0.34 ± 0.10 gr / dl with a value of p = 0.031 (p <0.05).Conclusion : The freeze dryer method (freeze dryer method ) for the Cork Fish Extract resulted in a higher increase in albumin levels than the liquid snakehead fish extract.Keywords: Preeclampsia, Hypoalbuminemia, freeze dryer method of Snakehead Fish Extract
The Relationship Between Magnesium Level in Pregnancy with Gestational Diabetes Mellitus Ambelina, Syntia; Djanas, Dovy; Bachtiar, Hafni
Andalas Obstetrics And Gynecology Journal Vol. 5 No. 1 (2021)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.1.102-111.2021

Abstract

Introduction : Magnesium is one of important micronutrients in pregnancy. Pregnant women needs higher magnesium intake than non-pregnant women at similar age. Decreased blood and cellular magnesium level was related to insulin resistance.Objective : To determine relationship between mean magnesium level in pregnant women with incidence of gestational diabetes mellitus.Methods : This was quantitative analytic study using cross sectional comparative design conducted in 8 Primary Health Care in Padang and 5 General Hospital in West Sumatra. This study was done from December 2019 until March 2020. Total sample collected was 36 samples consisted of 18 pregnant mother with gestational diabetes mellitus and 18 control sample with normal pregnancy, both were in gestational age between 24-28 weeks. Statistical analysis was done using independent sample T-test.Results : Mean magnesium level of pregnant mother with gestational diabetes mellitus was 1.85 ± 0.12 mg/dL, while in control sample was 2.10 ± 0.15 mg/dL. Statistical result using independent sample T-test showed significant correlation between mean magnesium level and incidence of gestational diabetes mellitus with p <0.001 (p value <0.05)Conclusion : Magnesium level during pregnancy is related to gestational diabetes mellitus incidence.Keywords: magnesium level, pregnant women, gestational diabetes mellitus
Correlation Between Levels of Interleukin-6 in Peritoneal Fluid With Degree of Pain, Adhesion, and Endometriosis Fertility Index Score in Endometriosis Prima, Angga Trifianda; Hendry, Dedy; Bachtiar, Hafni
Andalas Obstetrics And Gynecology Journal Vol. 5 No. 2 (2021)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.2.193-205.2021

Abstract

Introduction : Endometriosis is a benign gynecological disorder characterized by the presence of endometrial tissue and stroma outside the uterine cavity. Several theories have been proposed to explain the occurrence of endometriosis, one of which is the theory of inflammation. Endometriosis lesions can produce inflammatory cytokines, resulting in their increased levels in the peritoneal fluid. This process causes disruption in pelvic anatomy, ovarian function, prostaglandin production and growth factor production that causes pain, adhesions and infertility. Interleukin-6 (IL-6) is an important and potential inflammatory cytokine in assisting the diagnosis of endometriosis. These cytokines act as activating macrophages that can stimulate endometrial cell proliferation and modulate the secretion of other cytokines such as IL-10, IL-13 and TNF-α which augments the inflammatory process. High levels of IL-6 in the peritoneum are relatedto advanced endometriosis associated with pain, severe pelvic adhesions and embryotoxic effects leading to infertility. The effect of IL-6, both local and systemic, on the growth of endometriosis lesions and its associated symptoms is great that this cytokine is considered an important marker.Objective : This study aims to determine the relationship between local inflammatory factors (IL-6 in peritoneal fluid) obtained during laparoscopy with the degree of pain, the degree of adhesions and the correlation with the Endometriosis Fertility Index (EFI) score in endometriosis patients.Material and methods : This is a quantitative analytic research with a cross sectional study design which was conducted on 22 patients with endometriosis. Prior to the laparoscopy, historical factor (EFI score) was recorded and an assessment of the pain scale was performed by filling out a questionnaire. Intraoperatively, the peritoneal fluid was obtained. If the peritoneal fluid was found, it was taken directly with a volume of 3-5 cc using 10 cc syringe. If no fluid was found, peritoneal rinsing was performed using 0.9% NaCl fluid, then 3-5 cc fluid was aspirated using a 10 cc syringe. Subsequently, an examination was carried out using the RayBio Human IL-6 ELISA Kit. During the laparoscopy procedure, the degree of adhesion of the pelvic organs was assessed by looking at the shape and how the adhesions can be separated. Surgical factor (EFI score) was assessed intraoperatively to obtain data for the least function score, AFS endometriosis score and AFS total score. Statistical analysis was performed using paired t test and correlation test.Results : The mean age of the respondents was 34.86 ± 6.11 years, 81.8% were nulliparous, 100% were married, 100% experienced both primary and secondary infertility and 81.8% had no prior pregnancy history. In the study, it was found that IL-6 levels of peritoneal fluid were higher in patients with the degree of severe pain (P <0.05) compared to moderate with the results of 32.58 ± 7.31 pg/ml and 25.39 ± 2.70 pg/ml. IL-6 levels were found to be higher in grade three adhesions than grade two (P <0.05) with results of 32.78 ± 6.65 pg/ml and 23.86 ± 2.18 pg/ml. The mean peritoneal fluid IL-6 levels were 30.75 ± 7.01 pg/ml and the mean EFI score was 4.09 ± 2.09. The correlation of IL-6 levels in peritoneal fluid with EFI score showed a value of r = -0.448 which had moderate strength and a negative pattern, indicating that the higher the IL-6 level of peritoneal fluid, the lower the EFI score (P <0.05).Conclusion : There is a relationship between IL-6 levels of peritoneal fluid in endometriosis with the degree of pain and the degree of adhesion, where IL-6 levels were found to be higher in the degree of severe than moderate pain (P <0.05), higher in third degree adhesions than second degree ( P <0.05). There was a correlation between IL-6 levels of peritoneal fluid with EFI score (P <0.05) with a negative pattern of moderate strength analysis results (r = -0.448).Keywords: Endometriosis, Interleukin-6, Degree of Pain, Degree of Adhesion, Endometriosis Fertility Index Score
Factors Related to the Success of IVF Program in Morula BMC Clinic Padang Dewi, Nurmala Sari; Hendri, Dedy; Bachtiar, Hafni
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 1 (2022)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.50-57.2022

Abstract

Introduction: Infertility is the failure of a couple to get pregnant 12 months after having regular sex without contraception. One in seven couples even have to be treated using Assisted Reproductive Technology (TRB). The most widely used TRB is In Vitro Fertilization (IVF). In general, the success rate is in the range of 40-50%. In Indonesia, there are 32 clinics providing IVF program with a success rate of 30-40%. The success rate of IVF is influenced by multi variables that affect directly or indirectly including age, Antral Follicle Count (AFC), Anti Mullerian Hormone (AMH), basal Follicle Stimulating Hormone (FSH), number of egg cells, egg quality, sperm quality, embryo quality, and endometrial thickness. Objectives: This study aims to determine the factors associated with the success of IVF programMethods: This study used a cross-sectional analytic study design which was conducted on 77 medical records of patients undergoing IVF program at Morula Clinic BMC Padang from January 2018-December 2020. All data were then analyzed using univariate, bivariate and multivariate analysis with appropriate statistical test; Results: The average age of the study subjects was (33.4 ± 3.93) years, the average length of infertility was (6.73 ± 3.69) years, the most used antagonist protocols (88.16%), with the most common causes of infertility being factors sperm (48.9%) and overweight BMI (36.4%). From the bivariate analysis, it was found that the factors related to the number of eggs were age (r = -0.349), AFC (r = 0.471), FSH (p 0.02), and AMH (p < 0.01) with the dominant factor being AMH. Egg quality was related to AFC (p 0.007) and FSH (p 0.002), with the dominant factor being AFC. Embryo quality correlated with egg quality (p < 0.01). Meanwhile, the success of implantation was dominantly related to the embryo quality factor (0.034); Conclusion: The most dominant factor to the success of IVF program is the quality of the embryo.Keywords: IVF, IVF success
The relationship delay in referral with maternal mortality Dr. M. Djamil central general hospital Padang Hasjmy, Ibnu Razi Mulya; Ferry, Ferdinal; Bachtiar, Hafni
Andalas Obstetrics And Gynecology Journal Vol. 6 No. 1 (2022)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.71-81.2022

Abstract

Introduction: Maternal mortality is maternal death during pregnancy, childbirth, and 42 days after delivery. Maternal Mortality Rate (MMR) is the number of maternal deaths per 100,000 live births. There was an increase in MMR in Indonesia on 2012 compared to 2007 which is 228 per 100,000 population. There were 17 maternal deaths at Dr. M. Djamil Hospital throughout 2019. Delay in referral can cause death for both mother and infantObjectives: This study aims to determine the relationship between delay in referral and maternal mortality in obstetric emergencies that came to the emergency unit at Dr. M. Djamil Hospital, Padang.Methods: This study used a cross-sectional comparative study design conducted on 90 pregnant women who visited Dr. M. Djamil Padang Hospital from January - February 2021. All data were then analyzed using univariate and bivariate analysis with appropriate statistical tests.Results: The mean age of the study subjects was 25.34 ± 5.99 years old with 12.21% of sample were nullipara, 21.27% primipara, 61.83% multipara, and 4.58% grande multipara. From the questionnaire, 54.3% were late to refer. From the medical records, it was found that in the group who died, 94.5% experienced a delay in referral and bivariate analysis showed a relationship between late referral and maternal mortality (p = 0.000).Conclusion: There is a significant relationship between late referral and maternal mortality at Dr. M. Djamil Central General Hospital PadangKeywords: Maternal Mortality Rate; late referrals; pregnant women
EFEK SUPLEMEN KAPSUL JAHE MERAH TERHADAP REFLUX LARINGOFARINGEAL: Red Ginger and LPR Asyari, Ade; Julianda, Wahyu; Aliska, Gestina; Bachtiar, Hafni; Octavia, Tri Aryanti; Diflayzer, Diflayzer
Oto Rhino Laryngologica Indonesiana Vol. 54 No. 2 (2024): VOLUME 54, NO. 2 JULY - DECEMBER 2024
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v54i2.690

Abstract

Background: Ginger (Zingiber officinale) is a popular rhizome plant that used as a cooking and medicinal ingredient. Ginger contains many active compounds, such as phenolic and terpenes. Ginger has an anti-inflammatory effect through active ingredients, including diarylheptanoids, oleoresin, gingerol, shogaol and zingerone. Ginger powder is often used as a remedy for gastric acid reflux. In laryngopharyngeal reflux, there is a damage to the laryngopharyngeal mucosa due to irritation of gastric acid and pepsin. Purpose: To analyze the effect of red ginger powder capsule supplementation (Zyngiber officinale var. rubrum) on laryngopharyngeal reflux. Method: Non-randomized control trial study with a pretest-posttest control group design in laryngopharyngeal reflux. The patients were divided into two groups, where each group was examined for Reflux Symptom Index (RSI) and Reflux Finding Score (RFS). The intervention group was given red ginger powder capsules and lansoprazole, while the control group was given lansoprazole only; then a month later, both groups were examined for RSI and RFS finding score. Data were analyzed statistically with a computer program and were declared significant if p<0.05. Result: There was a significant difference between RSI and RFS in the intervention group, and there was no significant difference between RSI and RFS in the control group. Meanwhile, there were significant differences in RSI and RFS between the control and intervention groups. Conclusion: There was a significant difference between the reflux symptom index and reflux finding score between the intervention group and the control group. Keywords: red ginger, Zingiber officinale var. rubrum, laryngopharyngeal reflux, reflux symptom index, reflux finding score ABSTRAK Latar belakang: Jahe (Zingiber officinale) merupakan tanaman rimpang yang populer digunakan sebagai bahan masakan dan obat. Jahe mengandung banyak senyawa aktif, seperti senyawa fenolik dan terpena. Jahe memiliki efek anti-inflamasi melalui kandungan aktifnya, antara lain diarylheptanoida, oleoresin, gingerol, shogaol dan zingeron. Bubuk jahe sering digunakan sebagai pengobatan pada kasus refluks asam lambung. Pada kelainan refluks laringofaring, terjadi kerusakan pada mukosa laringofaring akibat iritasi asam lambung dan pepsin. Tujuan: Menganalisis pengaruh suplementasi kapsul serbuk jahe merah (Zingiber officinale var. rubrum) terhadap refluks laringofaring. Metode: Menggunakan metode non-randomized control trial, dengan pendekatan pretest-posttest control group design pada refluks laringofaring. Pasien dibagi menjadi dua kelompok, dan masing-masing kelompok diperiksa indeks gejala refluks, dan skor temuan refluks. Pada kelompok intervensi diberikan kapsul serbuk jahe merah dan lansoprazole, sedangkan pada kelompok kontrol diberikan lansoprazole saja; selanjutnya, satu bulan kemudian dilakukan pemeriksaan indeks gejala refluks dan skor temuan refluks. Data dianalisis secara statistik dengan program komputer dan dinyatakan signifikan jika p<0,05. Hasil: Terdapat perbedaan yang signifikan antara indeks gejala refluks dan skor temuan refluks pada kelompok intervensi, dan tidak terdapat perbedaan yang signifikan antara indeks gejala refluks dan skor temuan refluks pada kelompok kontrol. Sementara itu, terdapat perbedaan yang signifikan pada indeks gejala refluks dan skor temuan refluks antara kelompok kontrol dan intervensi. Kesimpulan: Terdapat perbedaan yang signifikan antara indeks gejala refluks dan skor temuan refluks antara kelompok intervensi dan kelompok kontrol. Kata kunci: jahe merah, Zingiber officinale var. rubrum, refluks laringofaring, indeks gejala refluks, skor temuan refluks